LOCUS       NM_131908                627 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus fibroblast growth factor 6 (Fgf6), mRNA.
ACCESSION   NM_131908
VERSION     NM_131908.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 627)
  AUTHORS   Cai Q, Wu G, Zhu M, Ge H, Xue C, Zhang Q, Cheng B, Xu S and Wu P.
  TITLE     FGF6 enhances muscle regeneration after nerve injury by relying on
            ERK1/2 mechanism
  JOURNAL   Life Sci 248, 117465 (2020)
   PUBMED   32105707
  REMARK    GeneRIF: FGF6 enhances muscle regeneration after nerve injury via
            ERK1/ERK2 activation.
REFERENCE   2  (bases 1 to 627)
  AUTHORS   Sautter NB, Delaney KL, Hausman FA and Trune DR.
  TITLE     Tissue remodeling in the acute otitis media mouse model
  JOURNAL   Int J Pediatr Otorhinolaryngol 75 (11), 1368-1371 (2011)
   PUBMED   21889218
REFERENCE   3  (bases 1 to 627)
  AUTHORS   Ropiquet F, Giri D, Kwabi-Addo B, Mansukhani A and Ittmann M.
  TITLE     Increased expression of fibroblast growth factor 6 in human
            prostatic intraepithelial neoplasia and prostate cancer
  JOURNAL   Cancer Res 60 (15), 4245-4250 (2000)
   PUBMED   10945637
REFERENCE   4  (bases 1 to 627)
  AUTHORS   Kastner S, Elias MC, Rivera AJ and Yablonka-Reuveni Z.
  TITLE     Gene expression patterns of the fibroblast growth factors and their
            receptors during myogenesis of rat satellite cells
  JOURNAL   J Histochem Cytochem 48 (8), 1079-1096 (2000)
   PUBMED   10898801
REFERENCE   5  (bases 1 to 627)
  AUTHORS   Sakuma K, Watanabe K, Sano M, Uramoto I and Totsuka T.
  TITLE     Differential adaptation of growth and differentiation factor
            8/myostatin, fibroblast growth factor 6 and leukemia inhibitory
            factor in overloaded, regenerating and denervated rat muscles
  JOURNAL   Biochim Biophys Acta 1497 (1), 77-88 (2000)
   PUBMED   10838161
REFERENCE   6  (bases 1 to 627)
  AUTHORS   Ornitz DM, Xu J, Colvin JS, McEwen DG, MacArthur CA, Coulier F, Gao
            G and Goldfarb M.
  TITLE     Receptor specificity of the fibroblast growth factor family
  JOURNAL   J Biol Chem 271 (25), 15292-15297 (1996)
   PUBMED   8663044
REFERENCE   7  (bases 1 to 627)
  AUTHORS   Grass S, Arnold HH and Braun T.
  TITLE     Alterations in somite patterning of Myf-5-deficient mice: a
            possible role for FGF-4 and FGF-6
  JOURNAL   Development 122 (1), 141-150 (1996)
   PUBMED   8565825
REFERENCE   8  (bases 1 to 627)
  AUTHORS   deLapeyriere O, Ollendorff V, Planche J, Ott MO, Pizette S, Coulier
            F and Birnbaum D.
  TITLE     Expression of the Fgf6 gene is restricted to developing skeletal
            muscle in the mouse embryo
  JOURNAL   Development 118 (2), 601-611 (1993)
   PUBMED   8223280
REFERENCE   9  (bases 1 to 627)
  AUTHORS   Dinwiddie SH, Reich T and Cloninger CR.
  TITLE     Solvent use and psychiatric comorbidity
  JOURNAL   Br J Addict 85 (12), 1647-1656 (1990)
   PUBMED   2289066
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB079674.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB079674.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760384, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..627
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..627
                     /gene="Fgf6"
                     /gene_synonym="Fgf7b"
                     /note="fibroblast growth factor 6"
                     /db_xref="GeneID:170700"
                     /db_xref="RGD:620130"
     CDS             1..627
                     /gene="Fgf6"
                     /gene_synonym="Fgf7b"
                     /note="fibroblast growth factor 7b"
                     /codon_start=1
                     /product="fibroblast growth factor 6"
                     /protein_id="NP_571983.1"
                     /db_xref="GeneID:170700"
                     /db_xref="RGD:620130"
                     /translation="MALGQRLFITMSRGAGRVQGTLQALVFLGVLVGMVVPSPAGARA
                     NGTLLDSRGWGTLLSRSRAGLAGEISGVNWESGYLVGIKRQRRLYCNVGIGFHLQVPP
                     DGRISGTHEENPYSLLEISTVERGVVSLFGVKSALFIAMNSKGRLYTTPSFQDECKFR
                     ETLLPNNYNAYESDLYRGTYIALSKYGRVKRGSKVSPIMTVTHFLPRI"
     exon            1..346
                     /gene="Fgf6"
                     /gene_synonym="Fgf7b"
                     /inference="alignment:Splign:2.1.0"
     exon            347..450
                     /gene="Fgf6"
                     /gene_synonym="Fgf7b"
                     /inference="alignment:Splign:2.1.0"
     exon            451..627
                     /gene="Fgf6"
                     /gene_synonym="Fgf7b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggccctgg gacagaggct gttcatcact atgtcccggg gagcaggacg tgttcagggc
       61 acgctgcagg ctctcgtctt cttaggcgtc ctagtgggca tggtggtgcc ctcacctgcc
      121 ggcgcccgcg ccaacggcac gctactggac tccagaggct ggggcaccct cttgtccagg
      181 tctcgagctg ggctagctgg agagatttcg ggtgtgaatt gggaaagtgg ctatttggtg
      241 ggcattaagc gacagcggag actctactgc aacgtgggca ttggcttcca cctccaggtg
      301 cctcccgacg gccggatcag tgggacgcac gaggagaacc cctacagcct gctggaaatc
      361 tccacggtag aacggggtgt ggtgagcctc tttggtgtga aaagtgctct cttcattgcc
      421 atgaacagta aaggaagact gtacacaacg cccagcttcc aggacgaatg caagttcaga
      481 gaaaccctcc ttccaaacaa ctacaacgcc tacgagtccg acctgtacag agggacctac
      541 attgcactga gcaaatatgg acgggtaaag cggggcagca aggtgtcccc aatcatgact
      601 gtcactcact tcctccccag gatataa
//
