LOCUS       NM_019198               1710 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus fibroblast growth factor 17 (Fgf17), transcript
            variant 1, mRNA.
ACCESSION   NM_019198
VERSION     NM_019198.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1710)
  AUTHORS   Olsen,S.K., Li,J.Y., Bromleigh,C., Eliseenkova,A.V., Ibrahimi,O.A.,
            Lao,Z., Zhang,F., Linhardt,R.J., Joyner,A.L. and Mohammadi,M.
  TITLE     Structural basis by which alternative splicing modulates the
            organizer activity of FGF8 in the brain
  JOURNAL   Genes Dev 20 (2), 185-198 (2006)
   PUBMED   16384934
REFERENCE   2  (bases 1 to 1710)
  AUTHORS   Xu,J., Lawshe,A., MacArthur,C.A. and Ornitz,D.M.
  TITLE     Genomic structure, mapping, activity and expression of fibroblast
            growth factor 17
  JOURNAL   Mech Dev 83 (1-2), 165-178 (1999)
   PUBMED   10381577
REFERENCE   3  (bases 1 to 1710)
  AUTHORS   Hoshikawa,M., Ohbayashi,N., Yonamine,A., Konishi,M., Ozaki,K.,
            Fukui,S. and Itoh,N.
  TITLE     Structure and expression of a novel fibroblast growth factor,
            FGF-17, preferentially expressed in the embryonic brain
  JOURNAL   Biochem Biophys Res Commun 244 (1), 187-191 (1998)
   PUBMED   9514906
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Sep 13, 2022 this sequence version replaced NM_019198.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB008682.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN17050745 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-594               JAXUCZ010000015.1  52126720-52127313   c
            595-631             JAXUCZ010000015.1  52126507-52126543   c
            632-809             JAXUCZ010000015.1  52123704-52123881   c
            810-916             JAXUCZ010000015.1  52123349-52123455   c
            917-1710            JAXUCZ010000015.1  52121191-52121984   c
FEATURES             Location/Qualifiers
     source          1..1710
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p11"
     gene            1..1710
                     /gene="Fgf17"
                     /gene_synonym="Fgf6b"
                     /note="fibroblast growth factor 17"
                     /db_xref="GeneID:29368"
                     /db_xref="RGD:2607"
     exon            1..594
                     /gene="Fgf17"
                     /gene_synonym="Fgf6b"
                     /inference="alignment:Splign:2.1.0"
     CDS             560..1210
                     /gene="Fgf17"
                     /gene_synonym="Fgf6b"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; FGF-17; fibroblast growth factor 6b"
                     /codon_start=1
                     /product="fibroblast growth factor 17 isoform 1 precursor"
                     /protein_id="NP_062071.1"
                     /db_xref="GeneID:29368"
                     /db_xref="RGD:2607"
                     /translation="MGAARLLPNLTLCLQLLILCCQTQGENHPSPNFNQYVRDQGAMT
                     DQLSRRQIREYQLYSRTSGKHVQVTGRRISATAEDGNKFAKLIVETDTFGSRVRIKGA
                     ESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPR
                     QASRSRQNQREAHFIKRLYQGQLPFPNHAERQKQFEFVGSAPTRRTKRTRRPQSQT"
     exon            595..631
                     /gene="Fgf17"
                     /gene_synonym="Fgf6b"
                     /inference="alignment:Splign:2.1.0"
     exon            632..809
                     /gene="Fgf17"
                     /gene_synonym="Fgf6b"
                     /inference="alignment:Splign:2.1.0"
     exon            810..916
                     /gene="Fgf17"
                     /gene_synonym="Fgf6b"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1710
                     /gene="Fgf17"
                     /gene_synonym="Fgf6b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagccagaat tcgagacccc agccccagct ccgtacctgc agctcattct taaggagatg
       61 agattgcggc atcaaacctg agggcgggag ctgctgaccc tgaggagggg ggagggcaag
      121 gcgcctccct ccctgtgcct gccgctggcc ccccgcactt ctcagagacc agcaggtccg
      181 tgcgggtcag gaataaatca agagagatcg cagggaccag cctcctgata gaggacgctc
      241 tcatagctcc atcctttgcg cccggggacc cctgcccgag gccagtagcc caagagagcg
      301 agtacgccaa tcggaccagc tccggcttcg cagcctcact ggcccggaag gtggacacct
      361 cgcacctcag tctctcaatt acgcctcccc ttcatccccc tctgctagct ttccccttcc
      421 ctccattctt tccatccctg aaaacctgtg gctccgagag accttggctt ctctgggact
      481 ctaccccagg ggcctgccca catccgctcc tgagtttggg gagcagaggg gcaaatcgcc
      541 ccaagaagtc tctccagcga tgggagccgc ccgcctgctg cctaacctta ccctgtgctt
      601 gcagctattg atcctctgct gtcaaacgca gggggagaat cacccgtctc ctaattttaa
      661 ccagtacgtg agggaccagg gcgctatgac tgaccagctg agcaggcggc aaatccgtga
      721 gtaccagctc tacagccgga ccagtggcaa gcacgtgcag gtcaccgggc gtcgcatctc
      781 tgccaccgct gaggatggca acaagttcgc caagctcatc gtggagacag acacattcgg
      841 cagcagagtc cgcatcaagg gggcagagag cgagaagtat atctgtatga acaagagggg
      901 caagctgatt gggaagccga gcgggaagag caaagactgc gtattcaccg agatcgtact
      961 ggagaacaac tacacagcct tccagaacgc ccggcatgag ggctggttca tggctttcac
     1021 ccggcagggc cggcctcgcc aggcctcccg gagccgccag aaccagcgag aggcccactt
     1081 catcaagcgc ctctaccaag gccagctgcc tttccccaac cacgctgaaa ggcagaagca
     1141 gttcgaattc gtgggctccg cccccactcg caggaccaag cgcactcgga ggccccagtc
     1201 ccaaacgtag tcagggaggc cttagtgtgc aaggctgggt agatgcccct caacagcctt
     1261 ccctcttttc tctaactcat ccaaagatgg gggctggggt ggaaggtggg gagccaaact
     1321 ccaaaaggac cccgagggca tgaagtttcc cactgggaag agacagtact tgtgtatccc
     1381 agggtgatca ccattttatg gaacaggttt gaagtcagag gcagacccca ggagaagaaa
     1441 tagggtcccc tgacctacat gcctgcttcc cagcgtctac ctgagataag caggcaggtc
     1501 agcagatttc aggtcttgca caactgtgcc caaatcttgc tctcagaacc tctctaaatc
     1561 tgaataacct aactcttggc cagacagtag ggactgtttt gtttccaaaa acagacagag
     1621 acagaaagaa acaaaagcca gtcacttttc atatttctcg ccccaggcct gccccacccc
     1681 cagccccaga ataaaaccat tttcctgtaa
//
