LOCUS       NM_001137645            4732 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus FYVE, RhoGEF and PH domain containing 6 (Fgd6),
            mRNA.
ACCESSION   NM_001137645 XM_001080375 XM_576214
VERSION     NM_001137645.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4732)
  AUTHORS   Gaudet P, Livstone MS, Lewis SE and Thomas PD.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473960.2.
            
            On or before Nov 14, 2008 this sequence version replaced
            XM_576214.2, XM_001080375.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4732
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..4732
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /note="FYVE, RhoGEF and PH domain containing 6"
                     /db_xref="GeneID:500824"
                     /db_xref="RGD:1565609"
     exon            1..323
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     CDS             308..4528
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /codon_start=1
                     /product="FYVE, RhoGEF and PH domain-containing protein 6"
                     /protein_id="NP_001131117.1"
                     /db_xref="GeneID:500824"
                     /db_xref="RGD:1565609"
                     /translation="MTSAVELKKPPLAPKPKLVGTNNKSPPPPIAPKPDIGNASVPRL
                     TKTKPAIAPKPKVLTNSDVQDVKDQPSKKLTLNLEEREPELPESTGKFNCKDVGDAHG
                     DYIFPTCSCSSGCTHEPRTRENLCAEQLVLEPLGMKEHLENGKNGESSKRGSRWNSSR
                     EKCRSQSGVVLKASIFEEKLKEVLTQPRSRSPSSSPRKHRCPNKPEMNGDHSCARQVR
                     IEFADTSSSQSSFGKAPHSCHTQPPRDKSQNLQTCQDGSAESLGPFHSCELEGKRGCS
                     GGTSQKSEVQGLGPVEIHLLPYTSKFPTPKPRRTHAARLRRQKHVDTPSESTEEPESS
                     NNGSSCLHEDSLKNNKVSVLHQNALSNQGPVDEVRPGNKKALTRESNSDRQDSVSSQK
                     AVQHETSSFEKVAPSLDTDSSLTSDSTVEDGSDVLPAVDRETAFIQCSPQPLSLPKQV
                     KLACAEQQPTTCNREVSVPQIQKESSSRIVPKKPQRHSLPAAGVLKKAASEELVEKNS
                     SSKETNSEKGLQRNHLQHLGPSNHGMSPSSFDMPNPTSEKPVWKLPHPILPFPGSPEA
                     LKRVTLSLNNEPSISLTKPRAKSLSAVDMDRCSKPCKEPPKKTTFKKLINVKLSIGFI
                     KSDFHKFKSKNCQHGDVSTGHSLGREPKGLENNWQGLATGEEKKSKPIKAYSEENCSL
                     ESQKVKSWSQSSATNGQRAESLDDQMLSRHASCQASSTSDCGPEYENVRHYEEIPEYE
                     NLPFVMARGNPPELGWQNSSSVEDTDVSLYEVEEPYDAPDGQLQLDPRHQPCSSGRCQ
                     DRQDELHLDLPSDEEVINSSDEDDVSSESSKGEPDPLEDKQDEDAGMKSKVHHIAKEI
                     MSSEKVFVDVLKLLHIDFRGAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLK
                     ELEERMLSWAEQQRIADIFVKKGPYLKMYSMYIKEFDKNIALLDEQCKKNSGFATVVR
                     EFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSVDHRDTQDALAVVIEV
                     ANHANDTMKQGDNFQKLMQIQYSLSGHHEIVQPGRVFLKEGILMKLSRKVMQPRMIFL
                     FNDALLYTTPMQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSAS
                     ERDDWLEAISRAIEEYAKKRITFCPSRSLDEDSERKEEVSPLGAKAPIWIPDTRATMC
                     MICTSEFTLTWRRHHCRACGKIVCQACSSNKCGLDYLKGQPARVCELCFQELQKLDHQ
                     LSPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSTMSGYLYRSK
                     GSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVAQVKDEHSDPRVFQLLHK
                     GLLFYVFKADDAHSTQRWIDAFQEGTVL"
     exon            324..2685
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            2686..2824
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            2825..2892
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            2893..2923
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            2924..3075
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            3076..3232
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            3233..3320
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            3321..3371
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            3372..3430
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            3431..3502
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            3503..3571
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            3572..3655
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            3656..3735
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            3736..3838
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            3839..3982
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            3983..4085
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            4086..4213
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            4214..4342
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            4343..4491
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
     exon            4492..4732
                     /gene="Fgd6"
                     /gene_synonym="RGD1565609"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actagatgag gaggggtgcg cgtccgcgaa gtcgcggcta gctcctctcg tgcgcgcgcc
       61 tggcggtcgt cccggagcgc ggcggagcgg cgctcgtgca cgtccccctg tcgctggccg
      121 ctagcgcccg gctccgccag agggtcgcgg gagccggcgt ccgtcctttg tgaggcgctc
      181 aggcggttcg gctggggtgc gggacggaat gtgggcactg cggggacttt tgtctcctgc
      241 tcaaactctg gggagcgtgg actgaactgg agccatggat tgagggcgtg tgctgcgcgg
      301 ggcagtcatg acttctgccg tggagctgaa gaagccacca ttggctccca agcctaagtt
      361 agtggggacc aataataagt caccgcctcc tcctattgcc cctaaaccgg acattggaaa
      421 tgctagtgtt ccacggttga cgaagaccaa accggcaatt gctccaaaac cgaaagtcct
      481 gacaaactca gatgttcaag acgtcaagga tcaaccctca aagaagctca ctttgaacct
      541 ggaggagcgg gagccagaat tacccgagag cactggcaag tttaattgca aagatgtcgg
      601 ggatgcacac ggtgattata ttttcccaac atgttcttgc agttctgggt gtactcatga
      661 gcctaggact cgcgaaaatc tgtgtgcaga gcagcttgtt ttagagcctc tgggaatgaa
      721 agaacattta gagaatggta aaaatggtga gtcctcaaag agggggagca gatggaattc
      781 aagccgtgaa aagtgccgga gccaaagtgg agttgtttta aaggcaagca tcttcgaaga
      841 gaagcttaaa gaggttctca cgcagccgag atcaaggtca cctagtagtt ccccaaggaa
      901 gcacagatgt ccaaataaac cagaaatgaa tggcgaccac agttgcgcca gacaggtcag
      961 aattgagttt gcagacacct cttcttccca gtccagcttc ggaaaagctc ctcacagctg
     1021 ccacacacaa cctcccaggg acaaatctca gaatctccag acttgtcaag atggcagtgc
     1081 tgagagcctt ggtccctttc attcatgtga gctggagggc aaaagagggt gttccggcgg
     1141 aactagtcag aagtcggagg tccaaggtct cggtcctgta gaaatccact tactaccgta
     1201 tacctcaaag tttccaacgc ccaagcccag aaggacacac gctgctcgtc tgcgtcgcca
     1261 gaagcatgta gacactccta gtgaaagcac tgaagagcca gagagctcaa acaatggctc
     1321 ttcttgtctc catgaagata gtttgaaaaa caataaagtc agtgttcttc atcagaatgc
     1381 tttgtctaac cagggaccag tggatgaggt gaggccagga aacaagaagg cattgaccag
     1441 ggagtccaac agtgacagac aggactcagt cagctcacag aaagctgtgc agcatgaaac
     1501 gtcttctttt gaaaaagtgg caccttcttt agatacagat tctagtttga cttctgacag
     1561 cacggtagaa gacggttctg atgtgttacc tgctgtggac agagagactg ctttcataca
     1621 atgcagtcct cagcctttga gcttgcctaa gcaagtcaaa ttagcctgtg ctgaacagca
     1681 gccaactacc tgcaacaggg aggtgtcagt gccccagata caaaaggaat cttcctcgag
     1741 aattgttccc aaaaaacctc aaagacacag cttgcctgcg gcaggggtgc ttaaaaaggc
     1801 tgcatcagag gaactagtag aaaagaactc ttcaagtaag gaaaccaatt cagagaaagg
     1861 tctgcaaaga aaccaccttc aacatttggg tccctcaaac catggcatgt caccgtcatc
     1921 ctttgatatg cccaacccaa cttcagaaaa gccagtatgg aagttacctc atcctattct
     1981 accttttccg gggagcccag aagccttgaa gcgggtcact ttatccttaa ataatgagcc
     2041 ttccatttcc ctaaccaagc caagagcaaa atccttgtct gctgtggata tggacaggtg
     2101 cagtaagcct tgcaaagagc ctccaaagaa aacgactttt aaaaagttga ttaacgtgaa
     2161 gctgtccatt ggtttcataa agagtgattt tcacaaattt aagtcaaaaa actgccaaca
     2221 tggggatgtc tctaccggac attcgctcgg tagagagcca aaagggcttg aaaataattg
     2281 gcaaggtttg gccacaggag aagagaagaa aagtaaaccc ataaaggcat attctgaaga
     2341 aaactgcagc ctggaatctc aaaaggtgaa atcttggagc cagagcagtg caactaatgg
     2401 tcagagagcg gagtctttgg atgaccagat gctctcccgg cacgcatcct gtcaggcctc
     2461 tagtacaagt gactgtgggc cagagtatga aaatgtccgc cattatgagg agataccaga
     2521 gtatgagaac ttgccttttg tcatggctcg agggaaccct ccagaattgg gatggcagaa
     2581 ttccagcagt gtggaggaca cggatgtaag tctgtatgaa gtggaagagc cctatgacgc
     2641 tccagatggc cagctgcaac ttgatccgag acatcagcct tgcagttctg gaagatgcca
     2701 ggacaggcag gatgagctcc atcttgacct gccttctgat gaggaagtca tcaatagttc
     2761 tgacgaagat gacgtcagct ccgagtccag taaaggcgag ccggacccgc tggaggataa
     2821 acaggatgaa gatgctggga tgaaaagcaa agtccatcat attgccaagg agatcatgag
     2881 ctcggagaaa gtgtttgtcg atgtgttaaa acttctgcat attgatttcc ggggtgctgt
     2941 agcccacgcg tccaggcaac tcgggaagcc cgtgattgag gaccggatcc ttaaccagat
     3001 cctgtactac ctgcctcagc tgtatgagct caaccgggat ctcctgaagg aactggagga
     3061 aagaatgctg agctgggctg aacaacagag aattgctgac atctttgtaa agaaggggcc
     3121 atatttaaaa atgtactcca tgtacatcaa agaattcgac aagaacattg cgttgctgga
     3181 tgaacagtgc aagaaaaact ctggattcgc cacggtcgtc agggaattcg agatgagccc
     3241 tcgatgtgcc aacctggccc tgaagcacta cctgctgaag ccagttcaga ggatccctca
     3301 gtataggctg ctgctgacag attatttaaa gaacctccta gaagactctg tagaccacag
     3361 agacacccaa gatgccctag ctgttgtcat agaggtagct aaccatgcca atgacaccat
     3421 gaagcaaggg gacaactttc agaagctcat gcaaattcag tacagcttga gtggacacca
     3481 tgaaatcgtg cagcctgggc gggtgtttct taaagaaggc atcctgatga agctgtctcg
     3541 gaaagtcatg cagccgcgaa tgattttcct gtttaatgat gctctactgt acaccacacc
     3601 catgcagtct gggatgtaca aactgaacaa catgctctcc ttggctggaa tgaaggtcag
     3661 aaaacctacc caggaggcat atcagaacga gttaaagatt gaaagtgtag agcgttcttt
     3721 catcctctca gcaagttctg cctcagaaag agacgactgg ctggaggcca tatccagggc
     3781 tatagaagag tatgccaaga aaagaatcac cttctgcccc agcaggagtc ttgatgagga
     3841 ctcagaaagg aaagaagaag tcagccctct tggggcaaag gctcccatct ggattcctga
     3901 caccagagcc accatgtgta tgatttgcac aagtgaattc accctgacct ggagaagaca
     3961 ccactgcagg gcctgtggga agatcgtgtg ccaagcttgc tcgtccaaca agtgtggctt
     4021 ggattacctg aaagggcagc cggcgagagt gtgcgagctc tgcttccaag agctgcagaa
     4081 actagatcac cagctgtccc ccaggattgg gtctcctgga aatcacaagt ctccttcaag
     4141 tgccttatct tcagtcttac atagcatccc ctcagggagg aaacagaaga aaatccctgc
     4201 tgccctcaaa gaagtgtcag cgaacacaga ggactccacc atgagcggct acctctacag
     4261 atccaagggc agtaaaaagc cgtggaaaca cctatggttc gtcatcaaga acaaagtgct
     4321 ctacacatac gctgcaagcg aggatgtggc agctttggaa agtcagccct tattgggatt
     4381 caccgtcgct caagtcaaag acgagcactc ggatcctaga gtgtttcagc tgctgcacaa
     4441 aggcttgctg ttctacgtgt tcaaggcaga cgacgcccac tccactcaga ggtggataga
     4501 cgcatttcag gagggcacag tattatagcc acactgactg cactgcctct gaggttccaa
     4561 caaggtggag aatggcataa aagctactca aaagccgtgt gaaaacgaac actgccaaga
     4621 caagtccacc caccgtcgtt gtgagataga gtgttttgtt aggtatatac agttcctaaa
     4681 aatgtctttc atgtttgtta tttattaaaa tgttgatgtt tactcgttgg tt
//
