LOCUS       NM_001108637            6321 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus FYVE, RhoGEF and PH domain containing 5 (Fgd5),
            mRNA.
ACCESSION   NM_001108637 XM_001076619 XM_006224993 XM_006236925 XM_342725
VERSION     NM_001108637.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6321)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 6321)
  AUTHORS   Bonaldo,M.F., Lennon,G. and Soares,M.B.
  TITLE     Normalization and subtraction: two approaches to facilitate gene
            discovery
  JOURNAL   Genome Res 6 (9), 791-806 (1996)
   PUBMED   8889548
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1 and BI289075.1.
            
            On or before Sep 4, 2019 this sequence version replaced
            XM_006236925.3, XM_006224993.3, NM_001108637.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments. This RefSeq transcript is based on
            orthologous transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN06621351,
                              SAMN06680436 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-246               JAXUCZ010000004.1  126054210-126054455
            247-2926            JAXUCZ010000004.1  126062452-126065131
            2927-3056           JAXUCZ010000004.1  126099813-126099942
            3057-3115           JAXUCZ010000004.1  126112304-126112362
            3116-3146           JAXUCZ010000004.1  126112454-126112484
            3147-3307           JAXUCZ010000004.1  126124075-126124235
            3308-3467           JAXUCZ010000004.1  126124458-126124617
            3468-3558           JAXUCZ010000004.1  126125131-126125221
            3559-3609           JAXUCZ010000004.1  126127333-126127383
            3610-3668           JAXUCZ010000004.1  126127937-126127995
            3669-3740           JAXUCZ010000004.1  126136045-126136116
            3741-3809           JAXUCZ010000004.1  126137108-126137176
            3810-3893           JAXUCZ010000004.1  126139443-126139526
            3894-3973           JAXUCZ010000004.1  126140930-126141009
            3974-4073           JAXUCZ010000004.1  126142259-126142358
            4074-4211           JAXUCZ010000004.1  126142633-126142770
            4212-4341           JAXUCZ010000004.1  126143220-126143349
            4342-4475           JAXUCZ010000004.1  126144282-126144415
            4476-4604           JAXUCZ010000004.1  126146401-126146529
            4605-4759           JAXUCZ010000004.1  126149684-126149838
            4760-6303           JAXUCZ010000004.1  126150154-126151697
            6304-6321           BI289075.1         1-18                c
FEATURES             Location/Qualifiers
     source          1..6321
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..6321
                     /gene="Fgd5"
                     /note="FYVE, RhoGEF and PH domain containing 5"
                     /db_xref="GeneID:362402"
                     /db_xref="RGD:1305589"
     exon            1..246
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     CDS             234..4796
                     /gene="Fgd5"
                     /codon_start=1
                     /product="FYVE, RhoGEF and PH domain-containing protein 5"
                     /protein_id="NP_001102107.2"
                     /db_xref="GeneID:362402"
                     /db_xref="RGD:1305589"
                     /translation="MHRADSPKPPVAPKPKVTTNPSTPPAKFPASQRPNSFPSPNSMS
                     RGPKPPIAPKPRLAGPSEYGAGVYLNNSLSKCSNGRLLCEDPSLYDGHHSTLNCLELE
                     TDEQYIMVPRAPQRDDALTDRATEKQGFEGEAQEHGTEQTGTERDLAAPDEEAPSRDS
                     EEGVDHALEDEEDCDHDLETDGTPTAPGEGAPSRDGEKGEEDCGQDPGVEEHPMSEEE
                     GEEEEAKECVHNRDDRAPWDGGEPFLNEVVLTHVCSQSPEVPCWEPGLPETPGEVDED
                     SEDICNNTELGKPNQDTGQDTEDASMGSPESEVSPDVQEQEAATDSPEVFEEDSVDAA
                     EGEDQIARDEPPNCEEDTNNRETAAATMQAGEDHGEDGDRVQEDPAEENCQIIPFESD
                     SVEEDCSPTLTENPYELFPTESTSFCNNSGSLAESDKGQESVCKICVEEVPGIGPSLS
                     QGDSLQDGSGEEAPVPEVVVVPENEDPMDDALSSPYVMGVGLLSLGEGAQSDTQAASG
                     TLSGYSTWEEGDSDGGQVPVDRKNIATRARPHSGKVAGHVPETVLEETGPEACSSAMG
                     IRDTGDEVRKIGILPEGKPSESLRALPAKPRAFTLYPRSFSVEGRESPLSMFREPEGA
                     GLDMHRVRRKEDNLSLPGAIGSSGSFSQRSHLPSSGTSTPSSVVDIPPPFDLACITKR
                     PITKSSPSLLIDGDTLEKASKKKKSSFKRFLELTFRKKTESKVHVDMSLSSSRSSSES
                     SYHGPARVLELDRRSLSNSPQLKCHTGKLRASDSPASLIFYRDSKRKGVPFSRTVSRV
                     ESFEDRSRPPFLPLPLTKPRSISFPNADTSDYENIPAMNSDYENIQIPPRRPARTGTF
                     TKLFEEQSRALSTANENDGYVDMSSFNAFESKQQSSEQEAESAYTEPYKVCPISTTPK
                     EDLTSDEEQGSSEEEDNASRDPSLSHKGEGQSRAFVIAQELLSSEKAYVQMLQHLSLD
                     FHGAVLRALENVEQEGREPLAQEELRQGLRELPAICDLHQGILESLEQRLGDCGEGQQ
                     QVADIFLAREQEFEHHAAHILQFDRYLGLLAESCLLSPRLATTVREFEQQSSQGGGQS
                     MKHRMLRVVQRLFQYQVLLTDYLNNLCPDSAEYDNTQSALNLISKVTDRANESMEQGE
                     NLQKLVHIEYSVRGQGDLLQPGREFLKEGTLMRVRGKSRHPRHLFLMNDTLLYTHPQK
                     DGKYRLKSSLPVANMKVSRPVMDKVPYALKIETPESCLTLSASSCAERDEWHYCLSRA
                     LPEDYKTQALAAFHHSVEIRERLGISLGERLPTLVPVTHAMMCMNCGCDFSLTVRRHH
                     CHACGKIVCRNCSRNKYPLKCLKNRMAKVCDGCFRELKLRNGPVPGPIRERPVSMSFP
                     LSSSRFSSGSTFSSVFQSISPSTFKKQKKVPSALAEVAASGEGSAISGYLSRCKSGKR
                     RWKKLWLVIKGKVLYTYLASEDKVAMESIPLLGFTIAPEKEEGSSEVGPVFHLYHKKT
                     LFYSFKAEDSSSAQRWMEAMEDASVL"
     exon            247..2926
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            2927..3056
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            3057..3115
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            3116..3146
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            3147..3307
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            3308..3467
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            3468..3558
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            3559..3609
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            3610..3668
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            3669..3740
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            3741..3809
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            3810..3893
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            3894..3973
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            3974..4073
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            4074..4211
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            4212..4341
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            4342..4475
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            4476..4604
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            4605..4759
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
     exon            4760..6304
                     /gene="Fgd5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaacatcta ggagcgggcg gaggcgcggc cggagcctgg agccccgagc ttgagcggac
       61 gccccgccca acccgagccc cgcgcccagc gcccctcgcc ttaccgcgga gtgctgcgcc
      121 cggggcgggc cgggccgggg cgggcgcggg cgcggtggac tgggcggcag tgggactccg
      181 acagacggac ccgcacagca cgcagcgacc agcctccggc tccgcggtgg aagatgcaca
      241 gagcagattc accaaaacca ccagttgctc ccaagccaaa ggttaccacc aatccttcca
      301 caccaccagc caagtttccc gcctcacaga ggcctaacag tttccccagt cccaactcca
      361 tgtccagggg ccccaaaccc cccattgctc ctaagcccag gttggctggc cccagtgagt
      421 atggagctgg tgtgtacctg aacaacagcc tcagcaaatg cagcaatggg aggctgctct
      481 gcgaggaccc gagcttgtac gatggacacc actccaccct gaactgcttg gagttggaga
      541 ctgatgagca gtacatcatg gtgcccaggg ctccacagag agacgatgcc ctcacagata
      601 gagctactga gaagcagggg tttgaggggg aagcccagga gcatggtacg gagcagacgg
      661 gaactgagag ggacctggca gctccagatg aagaggcacc gagcagagac agtgaggaag
      721 gcgtggacca cgctctggaa gatgaagaag actgtgatca tgatctagag acagatggga
      781 ccccaacggc cccaggtgaa ggagcaccaa gcagagacgg tgagaaaggc gaggaggact
      841 gtggtcagga ccccggtgtg gaggagcatc ccatgagcga ggaggaggga gaagaggagg
      901 aggcgaagga gtgcgtgcac aaccgtgatg acagggcacc ttgggatgga ggggagccct
      961 tcctcaatga ggtcgtcctc acacatgtct gctctcagtc ccctgaagtt ccttgttggg
     1021 agccaggcct tcctgagact cctggggagg tagatgagga tagcgaagac atctgtaaca
     1081 acacagaact cgggaaaccc aatcaggata ctggtcagga cacagaggat gccagcatgg
     1141 gatcccctga gagtgaggta tccccagatg tccaggagca agaggcagca acggacagcc
     1201 ctgaggtctt tgaggaggac tctgtagatg ctgcagaagg tgaggatcag atagcccggg
     1261 acgaaccacc caattgtgaa gaagacacca acaacagaga aactgcagca gccaccatgc
     1321 aggcgggaga ggatcatggg gaggatggag accgtgtgca agaggatcct gctgaggaga
     1381 actgccagat cattcccttt gagagtgaca gtgtggagga ggattgctca cccacactca
     1441 cagagaaccc ctatgagctt ttcccaacag agagcacctc cttctgtaat aacagcggtt
     1501 cccttgctga gtcggacaag gggcaagagt cagtgtgcaa gatctgtgta gaggaggttc
     1561 ctggtattgg cccctcactg agccagggtg attccttgca agatggatct ggagaggagg
     1621 ccccggtccc tgaggtggta gtcgtgccag agaatgagga tcccatggat gacgcgctca
     1681 gcagtcccta cgtgatggga gttggcttgc taagccttgg agagggagca cagtcagaca
     1741 cccaggctgc atcaggcact ctgagtgggt acagtacatg ggaggaaggg gactctgacg
     1801 ggggacaggt tccagtggac aggaagaata ttgccacaag ggcccggcct cactctggga
     1861 aggtggctgg tcacgttcca gaaactgttc tagaagaaac aggaccagaa gcctgttcat
     1921 cagccatggg catcagagat actggtgatg aggtgagaaa gataggtata ttgccggagg
     1981 gaaagccttc tgaatctctc cgggccttgc cagccaagcc cagagcattc actctctacc
     2041 caagatcctt ctctgtagaa ggccgggaga gtcccctgtc catgttccgg gaaccagagg
     2101 gagccgggct ggacatgcac cgtgtgagga ggaaagagga caacctctct ctgccaggtg
     2161 ccattggctc ctccggtagc ttctcacagc gtagccacct gccttccagt ggcacctcca
     2221 caccgtcctc tgtggttgac atcccgcccc ctttcgactt ggcctgcatc acgaagagac
     2281 ccatcactaa aagctcgccc tcactcctga tagatggaga caccttggaa aaagcctcca
     2341 agaagaagaa gtcctccttc aaacgcttcc tggagctgac attcaggaag aagacagaga
     2401 gcaaggtgca cgtggacatg agtctgtcgt cttccaggtc ctcctccgag tccagctacc
     2461 atggtccagc cagggtcctg gaacttgacc gcagaagcct cagcaactca ccccagctca
     2521 agtgccacac aggaaagctc cgggcctctg actctccggc ctccctcatc ttctacaggg
     2581 acagcaagag gaaaggcgtc cccttcagca ggacagtgtc cagagtggag tccttcgaag
     2641 accgctcccg gccgccattt ctgcctctgc ccctcaccaa gccacggtcc atctcatttc
     2701 ccaatgctga cacttcagac tatgagaaca ttccagccat gaactcagat tacgagaaca
     2761 tccagatccc acctcgcagg ccggcgagga cgggcacttt cacaaagctc tttgaagaac
     2821 agagtagagc cctgtccacc gcaaatgaaa acgacggcta cgtggacatg agcagcttca
     2881 atgccttcga gagcaagcag cagagttcag agcaggaagc tgagagcgcc tacactgagc
     2941 cctacaaggt ctgtcccatc tcaacaaccc ccaaagaaga cctcacatca gacgaagaac
     3001 agggaagctc agaggaggag gacaatgctt caagagaccc cagcctctca cacaagggtg
     3061 aaggacagtc tagagccttt gtcatcgctc aggagctgct gtcttcagag aaggcatatg
     3121 tgcagatgct gcagcactta agcctggatt tccatggagc cgtcctgagg gccttggaga
     3181 acgtagagca agagggcaga gagccactgg cccaggagga gctgcggcag ggcctacggg
     3241 agctcccagc tatctgtgac cttcaccagg gcatcctgga gagcctggag cagaggctgg
     3301 gggattgtgg agagggccag cagcaggtgg ccgacatctt cctagcccgt gagcaggagt
     3361 tcgaacatca tgctgcacac atcctgcaat ttgacaggta cctggggctg ctcgctgaga
     3421 gctgcctgct ctcaccccgg ctggccacca ccgtccggga atttgagcag cagagttcac
     3481 aagggggtgg ccagagcatg aaacatcgta tgctgcgtgt agtccagcgc ctcttccagt
     3541 accaagtgct gctcactgat tatttaaaca acctgtgccc ggactcagcc gagtacgaca
     3601 acactcagag tgctctgaat ctcatctcca aagtgacaga cagggctaat gaaagcatgg
     3661 aacaggggga aaacctgcag aagctggtcc acatcgagta cagtgtgcgg ggccaagggg
     3721 acctcctcca gccaggaagg gagttcctga aggaaggaac actgatgagg gtgagaggga
     3781 aaagccgaca cccccggcac ctgttcctga tgaatgacac gctcctgtac acgcaccccc
     3841 agaaggatgg gaagtaccgt ctgaagagct cgctaccagt ggccaacatg aaggtcagtc
     3901 gccctgtgat ggacaaagtg ccctatgctc tgaagatcga aactcccgag tcttgcctga
     3961 cactgtctgc aagctcatgt gccgaaaggg acgagtggca ctactgtctg agcagagccc
     4021 tcccggagga ctacaagact caggcgctgg ctgccttcca ccacagcgtg gagatccggg
     4081 agaggttggg gatcagcctc ggggagaggc tccccaccct ggtgcctgtc acgcatgcca
     4141 tgatgtgcat gaactgcggc tgtgacttct cgctcaccgt gaggcgccac cactgccatg
     4201 cctgtggcaa gattgtgtgc cggaactgct ctcgaaacaa gtacccactg aagtgcctca
     4261 agaacaggat ggccaaggtc tgcgatggct gcttccggga gctgaagctg aggaacgggc
     4321 ccgtccccgg ccccataaga gagcgtccgg tcagcatgag ttttccactg tcctcatccc
     4381 gcttctcctc gggcagcacc ttctcctctg tcttccagag tattagccct tcaactttca
     4441 agaagcagaa aaaagtccct tcggctttgg ctgaggtggc tgcatcagga gagggctctg
     4501 ccatcagcgg ctatttgagc cgctgtaaga gtggcaagcg gcgctggaag aaactctggc
     4561 ttgtcatcaa gggcaaagta ctctacacct acctggccag tgaggacaaa gtggccatgg
     4621 agagcatccc tctgctgggt tttactattg ccccagaaaa ggaggagggc agcagtgaag
     4681 tgggccctgt ttttcatctt tatcacaaga aaaccctgtt ttacagcttc aaagcagagg
     4741 acagcagttc tgctcagagg tggatggagg ccatggaaga tgccagtgtg ttatagcagt
     4801 caccaggcac atggactcac aacaaactcc tacattaaca cgtgaaccct tccagaagct
     4861 actcctgatc tcagcttatc tggatgcatg tgtgggttct gtgtggggct tgacctctct
     4921 cctcaaggtg gaaccccaaa agatatttat agacctcttt tctgcctcca tgttccccag
     4981 ccccaatcac agactgtact cttatctaaa agtgagttaa aatttagtac cttgaagaca
     5041 tggaaaccaa gagaaaaaga catttagcaa catgggcttt ttagtagaaa ctggcttttt
     5101 ctggttttac tcctggtgaa taggaccact ttcaactttt ccgcaatctc aaaatggtgc
     5161 ctcaggtgat gtgggaacca gacagaacgt atcagctgtg catctaagca ctttaccatc
     5221 cggctgagtt gtagcctcca gggctgtgtc ttccaaagga tggacaggag gcagctgcaa
     5281 acggggctag ggattcactt gcagtggaaa gtgactcctg cagccttatt gtcaccctaa
     5341 ggagggaggg gatcgtcttc ccctcctaag atcctactac ttgtactgcc aaagctttgc
     5401 tagagagtga cttcctctct ccaagaatcc tcataccagg actgcccgct aagtcatcac
     5461 agatccctca aacatggaag attgcatctg ctttaagttt ctgtgtgcat tcctgtgtcc
     5521 acactgtaca cactgaccac tctgttgatg ggagtttggc ctctctgtaa cacatatcct
     5581 ctggctgtac catccatgcc atgtttactt tttgagagag gtaaagaaga aagagagaag
     5641 gtgggtcatc agaaagtggt ctgtgctgat ggcttggcca gcgtagaggc actgagcagc
     5701 tggaagacgc tttgcatgct aagctgaacc accttgaagc tggaagatgc tttgcacacc
     5761 tgagcacctg aggctgacag caccatctcc ctctgggcac ctgaggcaga gtcatctcct
     5821 gctggccagt tctttatgct ggatggattt tacaaaatgc aggaggagga acaggattcc
     5881 tcctcactat cctgcagttg gaagaaaaaa aaatgccatc attttctgaa atctcttact
     5941 gcctagtccc ctccaaaaaa agatttttct acaaaactag catctcaagg acttacttac
     6001 attaaatatg ttcagggatt tctttttcta gtttgcagtt cttaatgttt ttgcagtctg
     6061 tgtgtaataa ttcaagttgg atggacagtg ttcctgttca cttcagcatg gattccccct
     6121 agagtcactc acatggggcc gggacaccag ggcccatgaa cctttacaga gtggagctgg
     6181 actcaagaag agtagtcccc tttctttggc ttcattgttt ttttctgtga tttcaattgc
     6241 aggtcaactg tggactgaaa atattaaatg gaaaattcca gaaataaaag tgcatgaatt
     6301 tccaaaaaaa aaaaaaaaaa a
//
