LOCUS       NM_001108409            2789 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus FYVE, RhoGEF and PH domain containing 3 (Fgd3),
            mRNA.
ACCESSION   NM_001108409 XM_001055555 XM_341505
VERSION     NM_001108409.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2789)
  AUTHORS   Pasteris,N.G., Nagata,K., Hall,A. and Gorski,J.L.
  TITLE     Isolation, characterization, and mapping of the mouse Fgd3 gene, a
            new Faciogenital Dysplasia (FGD1; Aarskog Syndrome) gene homologue
  JOURNAL   Gene 242 (1-2), 237-247 (2000)
   PUBMED   10721717
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473977.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001055555.1, XM_341505.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMD00132294, SAMEA5760393
                              [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2789
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..2789
                     /gene="Fgd3"
                     /note="FYVE, RhoGEF and PH domain containing 3"
                     /db_xref="GeneID:361223"
                     /db_xref="RGD:1311725"
     exon            1..62
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
     exon            63..219
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
     exon            220..710
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             270..2300
                     /gene="Fgd3"
                     /codon_start=1
                     /product="FYVE, RhoGEF and PH domain-containing protein 3"
                     /protein_id="NP_001101879.1"
                     /db_xref="GeneID:361223"
                     /db_xref="RGD:1311725"
                     /translation="MELGRSSPTPQEEAISPLGVPDAGLRSSPLGKLQALPFGSGAPQ
                     GAQGSSASAGDSSLGEPSGAMKIPNRDSGIESPSSSVASENFPCEEGSEGSPSPAILG
                     LHPEVAVDSRAPQDNPQEGEDSGVGEDPDPKITPCRPEEDVGSTQCSDPQKLLHIAQE
                     LLHTEEAYVKRLHLLDQVFCAKLTEAGIPPEVTTGIFSNISSIYRFHGQFLLPGLKKR
                     ITEEWDTKPRLGDILQKLAPFLKMYGEYVKNFDRAMGLVSTWTQRSPQFKDVIHTIQK
                     QEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPRDAPDRKDAERSLELISIAADHS
                     NAAIRKMEKMHKLLEVYEQLGGEEDIVNPANELIKEGNIQKLSAKNGTTQDRHLFLFN
                     NVMLYCVPKLRLMGQKFSVREKMDISDLQVQDVVKPNAARTFIITGRKRSLELQTRTE
                     EEKKEWIQIESRKLSSKTRRDKEKPGCKSCGETFNSITKRRYRCKLCGEVICRKCSEF
                     KAENSKQSRVCRECFLEEPLLPTSPSSETPTELKQNAEKPPSVDPRPSLLCGTLNLSD
                     NGTAWSEVWAAIPESDPQVLDLLAGSQAGKLLYSIPLSGCNITVPDPEEGLEAGYVWK
                     LHQGSQTWWLSAPSTKLQQRWLEALSTASRGDTAGDTPGASQPQTPASTDTP"
     exon            711..800
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
     exon            801..937
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
     exon            938..1094
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1095..1233
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1234..1292
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..1439
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1532
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1533..1612
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1613..1643
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1644..1766
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1767..1907
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1908..2048
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
     exon            2049..2789
                     /gene="Fgd3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgggtttttg ttcttgcatg agttcagccc tggaggagac gcagactggt cttggaagaa
       61 ggcaccttct aaacaactcc acttccagtg atctggacaa gacattttaa cagactgttt
      121 tagcctctgt tgggcaactc ccaaccaaag ccccagagga agccggtgcc tgttcattaa
      181 tccctgacag cctcattggg caacagcgtt gggcaacagg aagcccttgg ccagcctcct
      241 agcagagccc agggggtttg actgtgaaga tggaattggg taggagctcc ccaacacccc
      301 aagaagaagc catttcccct cttggggtac ctgatgctgg actcagaagc tccccactag
      361 ggaagcttca agcacttccc ttcgggtcag gagctcccca aggggctcag ggcagctcag
      421 cctcagcagg ggacagctcc ttgggggagc caagtggagc catgaagatc cccaacagag
      481 acagtggaat tgaaagccca tcctccagtg tggccagtga gaacttcccc tgtgaagagg
      541 gcagtgaggg gtctccaagc cctgccatcc tagggctaca ccctgaggta gctgtggaca
      601 gccgggcccc gcaggacaac ccccaggagg gagaagacag tggtgtgggc gaggaccctg
      661 accccaagat caccccgtgt aggcctgagg aggatgtcgg ctcgactcag tgctctgacc
      721 cacagaagct gcttcacatt gcccaggagc tcctgcacac ggaagaagcc tacgtgaagc
      781 ggctgcacct gctggaccag gttttctgtg ccaagctgac agaagcaggg atccctccgg
      841 aagtcaccac gggcatcttc tctaacatct cttctatcta ccgcttccac gggcagttcc
      901 tcctgcctgg actgaagaag aggatcacag aggagtggga tacaaagcct cgtctcggag
      961 acatcctgca gaaactggct ccgttcctga agatgtatgg cgagtacgtc aagaactttg
     1021 acagagcaat ggggctagtg agcacgtgga cccagcgttc tccgcagttt aaggacgtca
     1081 tccacaccat ccagaagcag gaggtgtgcg ggaacttgac cctgcagcat cacatgctgg
     1141 agcctgtgca gagggtcccc cgctatgagc tgctgctcaa ggactactta aagcggctcc
     1201 ccagggatgc cccggaccgg aaggatgctg agaggtcttt ggaactcatc tctatagctg
     1261 ctgaccactc caatgctgcc attaggaaga tggagaaaat gcacaagctc ttagaggtgt
     1321 atgagcagct gggtggggag gaggacatcg ttaacccagc caatgagctg atcaaggagg
     1381 gcaacatcca gaagttatca gccaagaatg gcaccactca ggaccgacac ctcttcttgt
     1441 tcaacaatgt gatgctctac tgcgtaccca aactaaggct catgggccag aagttcagtg
     1501 tacgggagaa aatggacatc tctgatctcc aggtgcaaga tgtcgtgaaa ccaaatgctg
     1561 cccgcacatt catcataaca ggacgaaaaa ggtccctgga gcttcagact cggaccgaag
     1621 aagagaagaa agaatggatt cagatcgagt ccagaaagct gtcctctaaa acaagacgcg
     1681 acaaagagaa gccgggatgt aaaagctgtg gtgagacctt caactccatc accaagagaa
     1741 ggtatcgctg caagctgtgt ggagaggtca tctgtaggaa gtgctctgag ttcaaggcgg
     1801 agaacagtaa gcagagccgt gtctgcagag agtgtttcct ggaggagccc ctgctcccta
     1861 caagtcctag ctctgagact cccaccgagc tcaaacagaa tgcagagaag cctccctctg
     1921 tggatcctcg gcccagcctg ctctgcggta ccctgaatct gtcagacaat ggtacggcct
     1981 ggagtgaggt gtgggcagcc atccctgagt cagatcccca ggtgctagac ctgctggcag
     2041 gcagccaggc tggcaaactg ctgtatagca tcccactctc tggctgtaat ataacagtgc
     2101 ctgaccccga ggaggggctg gaggctgggt atgtgtggaa gctgcatcag ggctcacaga
     2161 cctggtggct gagtgccccc tccacaaagc ttcagcagcg ctggctggaa gctctgagca
     2221 ctgcctcacg cggggacaca gccggggaca ccccaggggc ctcacagccc cagaccccag
     2281 caagcacgga caccccatga gcagagtctc ctactgtcct tcccactacc gtatttggcc
     2341 tgtgttcttt tatgggtgac cttagacgtc cagtgaagga gtgaagaagg actcctatga
     2401 ccactgagga tggaccaagt gcccagagaa gagtagcaat gggcccaaga tcactcaaca
     2461 agtcttagac aagagtcggg cttctggctc caacgccagc actgtggtga gagcatggag
     2521 agctgccact acaaagccaa tggcatccaa gcaggctgag tgatgacgcc agccctcaaa
     2581 ggcacaagga ggccaggtgg gcactgtcca ggggtgatca tgtccatcct ggtatgacat
     2641 cactctggga aaggtagagc tgtctgtggc ctgacctggt ctttgtctgt ctgtacactg
     2701 tgtgacctgg accatgactg ctcctctggg ctctacttct accctgccct ctccggaagc
     2761 attacttgtc tgctattcct gctgagcca
//
