LOCUS       NM_001107617            2770 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus FYVE, RhoGEF and PH domain containing 2 (Fgd2),
            mRNA.
ACCESSION   NM_001107617 XM_001069919 XM_228047
VERSION     NM_001107617.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2770)
  AUTHORS   Huber,C., Martensson,A., Bokoch,G.M., Nemazee,D. and Gavin,A.L.
  TITLE     FGD2, a CDC42-specific exchange factor expressed by
            antigen-presenting cells, localizes to early endosomes and active
            membrane ruffles
  JOURNAL   J Biol Chem 283 (49), 34002-34012 (2008)
   PUBMED   18838382
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Jan 9, 2008 this sequence version replaced NM_001107617.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582424.1907237.1,
                                           SRR26360194.2469579.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760494
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-244               JAXUCZ010000020.1  7426414-7426657
            245-476             JAXUCZ010000020.1  7429424-7429655
            477-557             JAXUCZ010000020.1  7430348-7430428
            558-706             JAXUCZ010000020.1  7430804-7430952
            707-863             JAXUCZ010000020.1  7432173-7432329
            864-1002            JAXUCZ010000020.1  7432478-7432616
            1003-1061           JAXUCZ010000020.1  7433097-7433155
            1062-1208           JAXUCZ010000020.1  7433358-7433504
            1209-1301           JAXUCZ010000020.1  7433972-7434064
            1302-1381           JAXUCZ010000020.1  7436277-7436356
            1382-1412           JAXUCZ010000020.1  7436447-7436477
            1413-1505           JAXUCZ010000020.1  7437300-7437392
            1506-1637           JAXUCZ010000020.1  7438150-7438281
            1638-1784           JAXUCZ010000020.1  7440580-7440726
            1785-1931           JAXUCZ010000020.1  7441874-7442020
            1932-2770           JAXUCZ010000020.1  7442369-7443207
FEATURES             Location/Qualifiers
     source          1..2770
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..2770
                     /gene="Fgd2"
                     /note="FYVE, RhoGEF and PH domain containing 2"
                     /db_xref="GeneID:309653"
                     /db_xref="RGD:1309840"
     exon            1..244
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
     CDS             180..2147
                     /gene="Fgd2"
                     /codon_start=1
                     /product="FYVE, RhoGEF and PH domain-containing protein 2"
                     /protein_id="NP_001101087.2"
                     /db_xref="GeneID:309653"
                     /db_xref="RGD:1309840"
                     /translation="MEQACAKQDSVCNLVAVFENSRSPGAAPGPHSFEDQPHSPEHQL
                     PLSPEPWEAPPAGEALTSEFRPVSRTYLNSLKNKLSSGAWRKSCQPGASPGPETQEPE
                     EKRVVQELLETEQAYVARLHLLDQVFFQELLREASRSKAFPEDVVKLIFSNISSIYRF
                     HAQFFLPELQRRVDDWTATPRIGDVIQKLAPFLKMYSEYVKNFERAAELLATWMDKSQ
                     PFQEVVTRIQRSEASGSLTLQHHMLEPVQRIPRYELLLKEYVQKLPAQAPDLEDAQRA
                     LDMIFSAAQHSNAAIAEMERLQGLWDVYQRLGLEDDIVDPSNTLLREGPVLKISFRRS
                     DPMERYLVLFNNMLLYCVPRVLQVGAQFQVRTRIDVAGMKVRELTDAEFPHSFLVSGK
                     QRTLELQARSREEMVSWIQACQAAIDQVEKRSETFKAAVQGPQGDTQEPKPQAEELGL
                     RAPQWVRDKMVTMCMRCQEPFNALTRRRHHCRACGYVVCAKCSDYRAELKYDGNRPNR
                     VCLTCYTFLTGNLLPDSKEDKRRGILEKETSAGPDQSVVCSFLQLMGDKSIRSIPRSW
                     CVIPRDDPLVLYVYAAPQDMKAHTSIPLLGYQVTSGPQGDPRVFQLQQSGQQYTFKAE
                     SVELQGRWVRAIKRAASGWTPEGPDEEDMSD"
     exon            245..476
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
     exon            477..557
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
     exon            558..706
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
     exon            707..863
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
     exon            864..1002
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1061
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1062..1208
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..1301
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1381
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1382..1412
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1413..1505
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1506..1637
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1638..1784
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1785..1931
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1932..2770
                     /gene="Fgd2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacttcctct tttatcgctc tgaagatagg aactgcccca gggcagtcag aagagatggg
       61 cagattccag gctgtggtag ccctgcttcc cgcgcaggcc agggagtgct gagggcgctg
      121 accgcttgcc ctcctccctg cttctggggt agctgaggac caccttgcag gctagcagaa
      181 tggagcaagc ctgtgcgaag caggactcag tgtgcaacct ggtggctgtg tttgagaaca
      241 gcaggtctcc gggagcagca cctggacccc atagttttga ggaccagccc catagccctg
      301 aacatcagct gcccctgtcc ccagagcctt gggaggcacc ccctgccggg gaggccttga
      361 cgtctgagtt ccggccagtc agcaggacat atctgaattc cctcaagaat aagctatcga
      421 gtggggcttg gaggaaatcc tgccaacctg gggccagtcc agggccggag actcaggaac
      481 ctgaggagaa gagggtcgtg caggagcttc tggagacgga gcaggcctac gtggctcgcc
      541 tgcacttgct tgaccaggtg ttcttccagg agctgctgag ggaggcgagc cgtagcaagg
      601 ccttccctga ggacgtggtg aagctcatct tctccaatat ctcctccatc taccgtttcc
      661 acgcacagtt cttcctcccg gagctgcaga ggcgcgtgga tgactggaca gccacaccac
      721 gcatcgggga tgtgatccag aaactggccc cctttctgaa aatgtacagc gagtacgtga
      781 agaactttga gcgggcggca gaactgctgg ccacctggat ggacaagtca cagcccttcc
      841 aggaggtggt cacccgcatc cagcgcagtg aggcctccgg cagcctgacc ctgcagcacc
      901 acatgttgga acctgtgcag agaatcccac ggtacgaact gctgctcaag gaatatgtgc
      961 agaagctgcc agcccaggcc ccagacctcg aagatgccca gagagcgctg gacatgatct
     1021 tctcagccgc acagcactcg aacgcagcca ttgctgagat ggagcggctg cagggcctgt
     1081 gggatgtgta ccagcgcctg ggcctggagg atgacattgt ggacccttcc aacaccctgc
     1141 tccgagaggg ccctgttctc aagatctctt tccgccgcag cgacccaatg gagcgctacc
     1201 tggttttgtt caacaacatg cttctgtact gcgtgccccg ggtcctccaa gtgggtgccc
     1261 agttccaggt gaggacccgc atcgacgtgg ctggcatgaa ggtgcgggag ctgacggacg
     1321 ctgagttccc gcactccttc ctggtatccg gcaagcagag aacgttggag ctgcaggccc
     1381 ggtctcgaga ggaaatggtt tcttggatac aggcctgcca ggcagctatt gaccaagtcg
     1441 agaagcgaag tgaaaccttc aaggctgctg tccagggacc tcagggggac acacaggagc
     1501 ccaagccaca ggcagaggag ctgggtctcc gagcacctca gtgggtccga gacaagatgg
     1561 tgaccatgtg tatgcgctgc caggagccct tcaatgccct gactcgtcgg cgtcaccact
     1621 gccgggcttg tggctacgta gtgtgtgcaa agtgttctga ctaccgtgcg gagctgaaat
     1681 atgacggcaa caggcccaac cgagtctgcc tgacctgcta cacgttcctc accggaaacc
     1741 tgctccctga cagcaaggag gacaagaggc gaggcatctt ggagaaagag acctccgcag
     1801 ggcccgacca gagtgtggtg tgcagtttcc tgcagctcat gggggacaag agtatcagga
     1861 gcattccccg gagctggtgt gtgatccccc gggatgaccc gcttgtgctg tatgtctatg
     1921 cagcccccca ggacatgaag gctcacacct ccatcccctt gctgggttat caggtgactt
     1981 cagggcccca gggggaccct cgggttttcc agctgcaaca gtcaggccag cagtacacct
     2041 tcaaggctga gtctgtggag ctgcagggcc gctgggtgag agctatcaag cgtgcggcca
     2101 gcggctggac ccccgaggga cctgacgaag aagacatgtc tgactgactg aaccacagct
     2161 ggctgctcat cgagaacctt gtccatgaca gttttcccac ggctctgtca ttttacccca
     2221 ggctacccct gacccatctg ttgtccatac caagatgatt cgtctgactc tgcatccagc
     2281 agacatgggt cctttccttc aggaaggcac acatgtccca gccggcttgg gggctgaaga
     2341 ctggggagga gggtgtcccc agaccacgct aaaatggaga agtatgacct acgtcgcagt
     2401 ttaatgggta gcgtgccggc ctagcatgca taaaaccctg ggttcattcc tcagcaacat
     2461 aaaccgggca tggtaataca tgccaacact tggatgggta gaggaaggag aacgaaaagt
     2521 cgaggttacc cttggctaca tagttaaggt ctaacatggg ctacatgaga aactcagcgc
     2581 atgcgcactc gcgcaaacac acatacacat caaagtaaaa tatgaaaagt gccagtaacc
     2641 aggaccgtcg gtgccctggt gagggtatga gcctggctgt gagtcggtca cctaggaagc
     2701 tttaaaaggg tccaggggaa aaaagagaca ccaactaact ttgaaattaa acaatgtccc
     2761 tgtctattca
//
