LOCUS       NM_053600               1982 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus fasciculation and elongation protein zeta 2
            (Fez2), transcript variant 1, mRNA.
ACCESSION   NM_053600 XM_342998
VERSION     NM_053600.3
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1982)
  AUTHORS   Spang,N., Feldmann,A., Huesmann,H., Bekbulat,F., Schmitt,V.,
            Hiebel,C., Koziollek-Drechsler,I., Clement,A.M., Moosmann,B.,
            Jung,J., Behrends,C., Dikic,I., Kern,A. and Behl,C.
  TITLE     RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced
            autophagy
  JOURNAL   Autophagy 10 (12), 2297-2309 (2014)
   PUBMED   25495476
REFERENCE   2  (bases 1 to 1982)
  AUTHORS   Fujita,T., Ikuta,J., Hamada,J., Okajima,T., Tatematsu,K.,
            Tanizawa,K. and Kuroda,S.
  TITLE     Identification of a tissue-non-specific homologue of axonal
            fasciculation and elongation protein zeta-1
  JOURNAL   Biochem Biophys Res Commun 313 (3), 738-744 (2004)
   PUBMED   14697253
  REMARK    GeneRIF: FEZ2 plays an important role in the morphological changes
            of various cells by associating with PKCzeta in a
            tissue-non-specific manner
REFERENCE   3  (bases 1 to 1982)
  AUTHORS   Imai,A., Nashida,T. and Shimomura,H.
  TITLE     mRNA expression of membrane-fusion-related proteins in rat parotid
            gland
  JOURNAL   Arch Oral Biol 46 (10), 955-962 (2001)
   PUBMED   11451410
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Dec 14, 2022 this sequence version replaced NM_053600.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB076183.1, SRR26360186.575846.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-261               JAXUCZ010000006.1  22406797-22407057
            262-370             JAXUCZ010000006.1  22411760-22411868
            371-487             JAXUCZ010000006.1  22419888-22420004
            488-629             JAXUCZ010000006.1  22422097-22422238
            630-898             JAXUCZ010000006.1  22424048-22424316
            899-979             JAXUCZ010000006.1  22438361-22438441
            980-1055            JAXUCZ010000006.1  22440550-22440625
            1056-1121           JAXUCZ010000006.1  22442981-22443046
            1122-1982           JAXUCZ010000006.1  22445885-22446745
FEATURES             Location/Qualifiers
     source          1..1982
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q12"
     gene            1..1982
                     /gene="Fez2"
                     /gene_synonym="Zrp"
                     /note="fasciculation and elongation protein zeta 2"
                     /db_xref="GeneID:94269"
                     /db_xref="RGD:619709"
     exon            1..261
                     /gene="Fez2"
                     /gene_synonym="Zrp"
                     /inference="alignment:Splign:2.1.0"
     CDS             11..1138
                     /gene="Fez2"
                     /gene_synonym="Zrp"
                     /note="isoform 1 is encoded by transcript variant 1;
                     zygin-2; zygin II; zygin-related protein types I/II;
                     synaptotagmin interacting protein zyginII"
                     /codon_start=1
                     /product="fasciculation and elongation protein zeta-2
                     isoform 1"
                     /protein_id="NP_446052.2"
                     /db_xref="GeneID:94269"
                     /db_xref="RGD:619709"
                     /translation="MAADGDWQDFYEFQEPAGSVRDQENCNASPEAGAGAHAGGDSFP
                     ALASSLEEKLSLCFRPTSDADPPRAAVRPITERSLLQGDEIWNALTDNYGNVMPVDWK
                     SSHTRTLHLLTLNLSEKGMSDGLPFDTSDEEELREQLDMHSIIVSCVNEEPLFTADQV
                     IEEIEEMMQESPDLEDDETPTQSDRLSMLSQEIQTLKSSSMSSCEERVKRLSVSELNE
                     LLEEIETAIKEYSEELVQQLALRDELEFEKEVENSFISALIEVQNKQKEHKETAKKKK
                     KLKNGSSQNGRNERSHMPGTRFSMEGISNVIQNGLRHTFGNSGGEKQYLTTVIPYEKK
                     NGPPSVEDLQILTKILHAMKEDSEKVPSLLTDYILKVLCPT"
     exon            262..370
                     /gene="Fez2"
                     /gene_synonym="Zrp"
                     /inference="alignment:Splign:2.1.0"
     exon            371..487
                     /gene="Fez2"
                     /gene_synonym="Zrp"
                     /inference="alignment:Splign:2.1.0"
     exon            488..629
                     /gene="Fez2"
                     /gene_synonym="Zrp"
                     /inference="alignment:Splign:2.1.0"
     exon            630..898
                     /gene="Fez2"
                     /gene_synonym="Zrp"
                     /inference="alignment:Splign:2.1.0"
     exon            899..979
                     /gene="Fez2"
                     /gene_synonym="Zrp"
                     /inference="alignment:Splign:2.1.0"
     exon            980..1055
                     /gene="Fez2"
                     /gene_synonym="Zrp"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1121
                     /gene="Fez2"
                     /gene_synonym="Zrp"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1982
                     /gene="Fez2"
                     /gene_synonym="Zrp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agccggcgcg atggcggcag acggggactg gcaggatttc tatgagttcc aggagccggc
       61 cgggagtgtc cgggaccagg agaactgtaa cgcgagcccg gaggctggag cgggggcaca
      121 cgcgggcggc gacagcttcc cggcgctggc ttccagcctg gaggagaagc tgagcctgtg
      181 cttccgcccc acgtcggacg ccgacccccc gcgggcggcc gtgcggccca tcacggagcg
      241 cagcctcttg caaggggacg agatttggaa tgccctgaca gataattatg ggaatgtcat
      301 gcctgtagac tggaagtcgt cccatacgag gaccttgcat ttgcttactc tgaacctctc
      361 agagaaaggg atgagtgatg gccttccctt cgacacctca gatgaggagg agctgaggga
      421 gcagctggat atgcattcaa tcattgtctc ctgtgtcaac gaggagcccc tcttcactgc
      481 agaccaggtt attgaagaaa ttgaagaaat gatgcaggag tcaccagacc tagaagacga
      541 tgagaccccc acacagtcag accggctctc catgctctcc caggagattc agactctcaa
      601 gagctctagc atgagcagct gtgaagagcg agtgaaaagg ctgtcagtgt ctgagctaaa
      661 cgaactgctg gaagaaattg agacggccat taaggagtac tctgaggagc tagtgcagca
      721 gttggccctg agagatgagc tggagtttga gaaggaagtg gagaacagct ttatttctgc
      781 tctgattgaa gtgcagaaca agcagaaaga acacaaggag acagccaaga agaagaagaa
      841 gctcaaaaat ggcagctctc agaatgggag gaatgagaga agtcacatgc caggcacacg
      901 cttcagcatg gaagggatct caaatgtcat tcagaatggc ctccgccaca cctttggaaa
      961 ctcaggtgga gagaaacagt atttgacgac agtcatccct tacgagaaaa agaatggccc
     1021 gccgtctgtg gaagatcttc aaatattaac aaaaattctg catgccatga aggaggacag
     1081 tgagaaagtt ccaagcttgt taacggacta tatactgaaa gttctgtgtc cgacatagag
     1141 cagcggtatg gtgggagccg cttccccttc tgtggactcc aggcttcatg acctatgctg
     1201 ttactctgga acatgctgtc acgactcccg gcttttggag acccagcaca cttgaacttg
     1261 gatttgcaat tcagtattaa tagatcatcc actaatccat cacgttatag cactacgaga
     1321 gcttcagcac tctggaattc tagagatagg atttggtata cataaccatt atgaactggt
     1381 ttctaagtta acagtcaagg agagggaggg atatggactg tgcatgctgt tgtttttgac
     1441 agtgtggctg ttaggttttg agttcctcca tctgaactga ctgaagaact aggttaaagc
     1501 acggggcgag ccaactgtag ctgttcttca gcgagggtga ggatcggtgc ttttagagca
     1561 tcttcagact attacctacc agtattgtcc agaaactgag attcagcgtg gctgctggga
     1621 aacagtgcca cccgccttca ctgctttcgc ctcattgtgg acgcctgacg cggttggaaa
     1681 ctgagttttg taatgtctgc ctgattcacc attgttggca tgcgagccgt taggatgcca
     1741 ttcacaatca ttatgaactt tgggtgtgtc tgtcccgtga agaagtgtat gttgaaaggg
     1801 gttcatgcct ctaaggtgct taaggagctg ctgaggtact gccttttctc atgggtgtgc
     1861 tcggttttat ttacacctat gtgcttttct agaaaaagct gctcatggct gcaacactaa
     1921 tcatgaacac ttttgccagt ttcaatcaaa tcagcggcat ttaataaaac agttcacact
     1981 ta
//
