LOCUS       NM_001108157            2199 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus fem-1 homolog B (Fem1b), mRNA.
ACCESSION   NM_001108157 XM_001074110 XM_236321
VERSION     NM_001108157.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2199)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 2199)
  AUTHORS   Shi,Y.Q., Liao,S.Y., Zhuang,X.J. and Han,C.S.
  TITLE     Mouse Fem1b interacts with and induces ubiquitin-mediated
            degradation of Ankrd37
  JOURNAL   Gene 485 (2), 153-159 (2011)
   PUBMED   21723927
REFERENCE   3  (bases 1 to 2199)
  AUTHORS   Nishiyama,A., Xin,L., Sharov,A.A., Thomas,M., Mowrer,G., Meyers,E.,
            Piao,Y., Mehta,S., Yee,S., Nakatake,Y., Stagg,C., Sharova,L.,
            Correa-Cerro,L.S., Bassey,U., Hoang,H., Kim,E., Tapnio,R., Qian,Y.,
            Dudekula,D., Zalzman,M., Li,M., Falco,G., Yang,H.T., Lee,S.L.,
            Monti,M., Stanghellini,I., Islam,M.N., Nagaraja,R., Goldberg,I.,
            Wang,W., Longo,D.L., Schlessinger,D. and Ko,M.S.
  TITLE     Uncovering early response of gene regulatory networks in ESCs by
            systematic induction of transcription factors
  JOURNAL   Cell Stem Cell 5 (4), 420-433 (2009)
   PUBMED   19796622
REFERENCE   4  (bases 1 to 2199)
  AUTHORS   Sun,T.P. and Shieh,S.Y.
  TITLE     Human FEM1B is required for Rad9 recruitment and CHK1 activation in
            response to replication stress
  JOURNAL   Oncogene 28 (18), 1971-1981 (2009)
   PUBMED   19330022
REFERENCE   5  (bases 1 to 2199)
  AUTHORS   Wang,X., Desai,N., Hu,Y.P., Price,S.M., Abate-Shen,C. and Shen,M.M.
  TITLE     Mouse Fem1b interacts with the Nkx3.1 homeoprotein and is required
            for proper male secondary sexual development
  JOURNAL   Dev Dyn 237 (10), 2963-2972 (2008)
   PUBMED   18816836
REFERENCE   6  (bases 1 to 2199)
  AUTHORS   Kamura,T., Maenaka,K., Kotoshiba,S., Matsumoto,M., Kohda,D.,
            Conaway,R.C., Conaway,J.W. and Nakayama,K.I.
  TITLE     VHL-box and SOCS-box domains determine binding specificity for
            Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases
  JOURNAL   Genes Dev 18 (24), 3055-3065 (2004)
   PUBMED   15601820
REFERENCE   7  (bases 1 to 2199)
  AUTHORS   Chan,S.L., Tan,K.O., Zhang,L., Yee,K.S., Ronca,F., Chan,M.Y. and
            Yu,V.C.
  TITLE     F1Aalpha, a death receptor-binding protein homologous to the
            Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase
            substrate that mediates apoptosis
  JOURNAL   J Biol Chem 274 (45), 32461-32468 (1999)
   PUBMED   10542291
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473975.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_236321.3, XM_001074110.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2199
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..2199
                     /gene="Fem1b"
                     /note="fem-1 homolog B"
                     /db_xref="GeneID:315745"
                     /db_xref="RGD:1304569"
     exon            1..501
                     /gene="Fem1b"
                     /inference="alignment:Splign:2.1.0"
     CDS             254..2137
                     /gene="Fem1b"
                     /note="FEM1-beta; feminization 1 homolog b; feminization
                     of XX and XO animals 1B"
                     /codon_start=1
                     /product="protein fem-1 homolog B"
                     /protein_id="NP_001101627.1"
                     /db_xref="GeneID:315745"
                     /db_xref="RGD:1304569"
                     /translation="MEGLAGYVYKAASEGKVLTLAALLLNRSESDIRYLLGYVSQQGG
                     QRSTPLIIAARNGHAKVVRLLLEHYRVQTQQTGTVRFDGYVIDGATALWCAAGAGHFE
                     VVKLLVSHGANVNHTTVTNSTPLRAACFDGRLDIVKYLVENNANISIANKYDNTCLMI
                     AAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEAGHIDIVKELIKWRAAIVVNGH
                     GMTPLKVAAESCKADVVELLLSHADCDRRSRIEALELLGASFANDRENYDIMKTYHYL
                     YLAMLERFQDGDNILEKEVLPPIHAYGNRTECRNPQELEAIRQDRDALHMEGLIVRER
                     ILGADNIDVSHPIIYRGAVYADNMEFEQCIKLWLHALHLRQKGNRNTHKDLLRFAQVF
                     SQMIHLNEAVKAPDIECVLRCSVLEIEQSMNRVKNISDADVHSAMDNYECNLYTFLYL
                     VCISTKTQCSEEDQCRINKQIYNLIHLDPRTREGFTLLHLAVNSNTPVDDFHTNDVCS
                     FPNALVTKLLLDCGAEVNAVDNEGNSALHIIVQYNRPISDFLTLHSIIISLVEAGAHT
                     DMTNKQNKTPLDKSTTGVSEILLKTQMKMSLKCLAARAVRANDINYQDQIPRTLEEFV
                     GFH"
     exon            502..2199
                     /gene="Fem1b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcctggggcc tcgggggcgg ccctgaccgt ccttcttccc gccccggccg ggtcacagtt
       61 gtgcctccag cggcgctcgg ccacctctgt gtctccgccc tcgctgggtc gcgctgctgc
      121 ctgggcgcgg cggcggcgcc ctgttgaatg ggctgtgagg gcccgggtct gaagtgctgg
      181 tggacgcggc ctccgggggc gcaaggcagc agcagcggtg gcgaccaaac gggtgttgga
      241 gttggcggcg gccatggagg gcctggctgg ttatgtgtac aaggcggcca gcgagggcaa
      301 ggtgctcact ctggctgcct tgctccttaa ccggtcagaa agcgatatcc gctacctgct
      361 gggctatgtc agtcagcagg gaggacagcg ctccacaccc ctcatcatcg cagcccgcaa
      421 tgggcacgcc aaggtggtgc gcttgctgtt agaacactac cgtgtgcaga cccagcagac
      481 tggcaccgtc cgcttcgacg ggtatgtcat tgatggtgcc actgctcttt ggtgtgctgc
      541 gggagccgga cattttgaag ttgttaaact tctagtcagc catggagcca acgtgaacca
      601 caccacagtc actaactcaa ctccattgcg ggcagcgtgc tttgatggta gactggacat
      661 tgtgaaatat ttggttgaaa ataatgccaa tatcagcatt gccaacaagt atgacaacac
      721 ctgcctaatg atcgcagcat ataaggggca caccgatgtt gtcagatacc tcttagaaca
      781 gcgtgctgac cccaatgcta aagcacactg tggagccaca gctttgcact tcgcagccga
      841 agctggtcac attgacattg tgaaagaact gataaaatgg cgagccgcaa tagtagtaaa
      901 tggccacggg atgacaccgt tgaaggtagc tgctgaaagc tgtaaagctg atgtcgttga
      961 actgttgctc tctcatgccg attgtgaccg cagaagtcgg attgaagcct tggagctctt
     1021 gggtgcctcc tttgcaaatg accgtgagaa ctatgacatc atgaagacat accactattt
     1081 atatttagct atgttggaga ggtttcagga tggtgacaac attcttgaga aagaggttct
     1141 tccacccatc catgcttatg ggaacagaac tgaatgtagg aacccacagg aattggaggc
     1201 tattcggcaa gacagagatg ctcttcacat ggagggcctt atcgtgcgag aacggatttt
     1261 aggtgctgac aacattgatg tttcccatcc catcatttac agaggggctg tctatgctga
     1321 caacatggag ttcgagcagt gcatcaaatt gtggcttcac gcgctgcacc tcagacagaa
     1381 aggaaataga aatacccaca aggatctgct tcggtttgct caagtcttct cacagatgat
     1441 acacctcaat gaagctgtga aggccccaga catagaatgc gttttgagat gcagtgtctt
     1501 ggaaatagag cagagcatga acagagttaa aaatatctcc gatgctgacg tccacagtgc
     1561 catggataac tatgagtgta acctctatac ctttctgtac cttgtgtgca tctccaccaa
     1621 gacacagtgt agcgaagaag accagtgcag aattaacaag cagatctaca acctgattca
     1681 cctggacccc agaacacggg aaggtttcac cttgctacac ttggccgtca actcgaacac
     1741 accagtcgat gatttccaca ccaatgatgt ctgcagcttt cccaatgcac tggtcacaaa
     1801 gctcctgctg gactgtggtg ctgaggtaaa tgctgtggac aatgagggga acagtgccct
     1861 ccacattatc gtccagtaca acaggcccat cagtgatttt ctgaccttgc actccatcat
     1921 cattagcctt gtggaagctg gagctcatac cgacatgaca aacaagcaga ataaaactcc
     1981 gctagacaaa agtacaactg gggtgtctga aatactactt aaaactcaga tgaagatgag
     2041 cctcaagtgc ctggctgccc gagcagttcg ggctaatgac attaactacc aagaccagat
     2101 cccccggact cttgaagagt ttgttggatt tcattaagtg actggatgtg taaaatcgtt
     2161 taatgtggtg ctaaaaagta aaggacttta atcacagac
//
