LOCUS       NM_017126                837 bp    mRNA    linear   ROD 05-DEC-2024
DEFINITION  Rattus norvegicus ferredoxin 1 (Fdx1), mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_017126
VERSION     NM_017126.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 837)
  AUTHORS   Zulkifli,M., Okonkwo,A.U. and Gohil,V.M.
  TITLE     FDX1 Is Required for the Biogenesis of Mitochondrial Cytochrome c
            Oxidase in Mammalian Cells
  JOURNAL   J Mol Biol 435 (23), 168317 (2023)
   PUBMED   37858707
  REMARK    GeneRIF: FDX1 Is Required for the Biogenesis of Mitochondrial
            Cytochrome c Oxidase in Mammalian Cells.
REFERENCE   2  (bases 1 to 837)
  AUTHORS   Maio,N. and Rouault,T.A.
  TITLE     Iron-sulfur cluster biogenesis in mammalian cells: New insights
            into the molecular mechanisms of cluster delivery
  JOURNAL   Biochim Biophys Acta 1853 (6), 1493-1512 (2015)
   PUBMED   25245479
  REMARK    Review article
REFERENCE   3  (bases 1 to 837)
  AUTHORS   Strushkevich,N., MacKenzie,F., Cherkesova,T., Grabovec,I.,
            Usanov,S. and Park,H.W.
  TITLE     Structural basis for pregnenolone biosynthesis by the mitochondrial
            monooxygenase system
  JOURNAL   Proc Natl Acad Sci U S A 108 (25), 10139-10143 (2011)
   PUBMED   21636783
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15535]
REFERENCE   4  (bases 1 to 837)
  AUTHORS   Miller,W.L.
  TITLE     Androgen synthesis in adrenarche
  JOURNAL   Rev Endocr Metab Disord 10 (1), 3-17 (2009)
   PUBMED   18821018
  REMARK    Review article
REFERENCE   5  (bases 1 to 837)
  AUTHORS   Izumi,S. and Mitani,F.
  TITLE     Gonadotropin stimuli increase adrenodoxin immunoreactivity in the
            mitochondria of rat ovarian cells
  JOURNAL   Acta Histochem 107 (4), 269-277 (2005)
   PUBMED   16139340
REFERENCE   6  (bases 1 to 837)
  AUTHORS   Itoh,S., Iemura,O., Yamada,E., Yoshimura,T., Tsujikawa,K.,
            Kohama,Y. and Mimura,T.
  TITLE     cDNA cloning of mouse ferredoxin reductase from kidney
  JOURNAL   Biochim Biophys Acta 1264 (2), 159-162 (1995)
   PUBMED   7495857
REFERENCE   7  (bases 1 to 837)
  AUTHORS   Sagara,Y., Matsunaga,K., Nakamura,K., Aramaki,H., Watanabe,Y.,
            Hara,T., Sekimizu,K. and Horiuchi,T.
  TITLE     Purification and characterization of rat adrenodoxin
  JOURNAL   Biochimie 77 (9), 719-723 (1995)
   PUBMED   8789462
REFERENCE   8  (bases 1 to 837)
  AUTHORS   Rogler,L.E. and Pintar,J.E.
  TITLE     Expression of the P450 side-chain cleavage and adrenodoxin genes
            begins during early stages of adrenal cortex development
  JOURNAL   Mol Endocrinol 7 (3), 453-461 (1993)
   PUBMED   8097866
REFERENCE   9  (bases 1 to 837)
  AUTHORS   Mellon,S.H., Kushner,J.A. and Vaisse,C.
  TITLE     Expression and regulation of adrenodoxin and P450scc mRNA in rodent
            tissues
  JOURNAL   DNA Cell Biol 10 (5), 339-347 (1991)
   PUBMED   1863358
REFERENCE   10 (bases 1 to 837)
  AUTHORS   Hanukoglu,I., Suh,B.S., Himmelhoch,S. and Amsterdam,A.
  TITLE     Induction and mitochondrial localization of cytochrome P450scc
            system enzymes in normal and transformed ovarian granulosa cells
  JOURNAL   J Cell Biol 111 (4), 1373-1381 (1990)
   PUBMED   2170421
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Nov 26, 2020 this sequence version replaced NM_017126.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D50436.1, FN802346.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676788, SAMN16676808
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-261               JAXUCZ010000008.1  61183385-61183645   c
            262-386             JAXUCZ010000008.1  61177336-61177460   c
            387-516             JAXUCZ010000008.1  61169336-61169465   c
            517-837             JAXUCZ010000008.1  61164839-61165159   c
FEATURES             Location/Qualifiers
     source          1..837
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..837
                     /gene="Fdx1"
                     /note="ferredoxin 1"
                     /db_xref="GeneID:29189"
                     /db_xref="RGD:62036"
     exon            1..261
                     /gene="Fdx1"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..631
                     /gene="Fdx1"
                     /note="adrenodoxin, mitochondrial; adrenal ferredoxin"
                     /codon_start=1
                     /product="adrenodoxin, mitochondrial precursor"
                     /protein_id="NP_058822.2"
                     /db_xref="GeneID:29189"
                     /db_xref="RGD:62036"
                     /translation="MAAAPGARLLRAACASVAFRGLDCRRLLVCGTRAGPAIPQWTPS
                     PHTLAEAGPGRPLSVSARARSSSEDKVTVHFKNRDGETLTTKGKVGDSLLDVVIENNL
                     DIDGFGACEGTLACSTCHLIFEDHIYEKLDAITDEENDMLDLAFGLTNRSRLGCQVCL
                     TKAMDNMTVRVPEAVADVRQSVDMSKNS"
     exon            262..386
                     /gene="Fdx1"
                     /inference="alignment:Splign:2.1.0"
     exon            387..516
                     /gene="Fdx1"
                     /inference="alignment:Splign:2.1.0"
     exon            517..837
                     /gene="Fdx1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggacccagg ggacccttgg cactgcgcag gaccccgcgg gacccggaac cttccgacag
       61 ggttatggcg gccgctccgg gcgcccgact cctgcgcgct gcctgcgcct ccgtcgcttt
      121 tcgtggtctg gactgccgtc ggctgctggt ctgcgggacc cgtgcgggac ctgccatccc
      181 tcagtggacc ccgagccccc acacgcttgc agaggccgga cctggccggc cactgagcgt
      241 gtctgcgcgc gcgcggagta gctcagaaga taaggtaaca gtccacttca agaaccgaga
      301 tggtgaaacg ctaacgacca aggggaaagt tggtgactct ctgctagatg ttgtgattga
      361 gaataaccta gatatcgatg gatttggtgc gtgtgagggg actttggctt gctctacctg
      421 tcatcttatc tttgaggacc atatatatga gaagttagat gccattactg atgaagagaa
      481 cgacatgctt gacctggctt ttggactaac aaacaggtca cggctgggct gtcaagtttg
      541 tctgaccaag gctatggaca atatgactgt ccgtgtgcct gaagcagtgg cagatgtccg
      601 acagtctgtt gacatgagca agaattccta agctacaata aaaagaatat tttcattaaa
      661 tttttaccta tttttataat tatttcttag cataattgat tatatggcaa aatatgtagc
      721 tgtgctgtct tagttcagtt ttgtagtact gaaaatttgc agtttttatt ttgattaaat
      781 tattaaaata tcagtctatt agaagacagc tgatacaata aactccttat gtatttt
//
