LOCUS       NM_001109881            2616 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus FCH and double SH3 domains 1 (Fchsd1), mRNA.
ACCESSION   NM_001109881
VERSION     NM_001109881.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2616)
  AUTHORS   Becalska,A.N., Kelley,C.F., Berciu,C., Stanishneva-Konovalova,T.B.,
            Fu,X., Wang,S., Sokolova,O.S., Nicastro,D. and Rodal,A.A.
  TITLE     Formation of membrane ridges and scallops by the F-BAR protein
            Nervous Wreck
  JOURNAL   Mol Biol Cell 24 (15), 2406-2418 (2013)
   PUBMED   23761074
REFERENCE   2  (bases 1 to 2616)
  AUTHORS   Cao,H., Yin,X., Cao,Y., Jin,Y., Wang,S., Kong,Y., Chen,Y., Gao,J.,
            Heller,S. and Xu,Z.
  TITLE     FCHSD1 and FCHSD2 are expressed in hair cell stereocilia and
            cuticular plate and regulate actin polymerization in vitro
  JOURNAL   PLoS One 8 (2), e56516 (2013)
   PUBMED   23437151
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            On Feb 10, 2021 this sequence version replaced NM_001109881.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.62565.1,
                                           SRR26643297.49935.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-46                JAXUCZ010000018.1  30055628-30055673   c
            47-144              JAXUCZ010000018.1  30055277-30055374   c
            145-190             JAXUCZ010000018.1  30054667-30054712   c
            191-258             JAXUCZ010000018.1  30054122-30054189   c
            259-400             JAXUCZ010000018.1  30053667-30053808   c
            401-537             JAXUCZ010000018.1  30053447-30053583   c
            538-601             JAXUCZ010000018.1  30053292-30053355   c
            602-730             JAXUCZ010000018.1  30052298-30052426   c
            731-853             JAXUCZ010000018.1  30051772-30051894   c
            854-949             JAXUCZ010000018.1  30051512-30051607   c
            950-1069            JAXUCZ010000018.1  30050792-30050911   c
            1070-1174           JAXUCZ010000018.1  30050315-30050419   c
            1175-1336           JAXUCZ010000018.1  30050020-30050181   c
            1337-1465           JAXUCZ010000018.1  30049047-30049175   c
            1466-1549           JAXUCZ010000018.1  30048883-30048966   c
            1550-1667           JAXUCZ010000018.1  30048625-30048742   c
            1668-1888           JAXUCZ010000018.1  30048281-30048501   c
            1889-1976           JAXUCZ010000018.1  30047344-30047431   c
            1977-2032           JAXUCZ010000018.1  30045808-30045863   c
            2033-2616           JAXUCZ010000018.1  30045106-30045689   c
FEATURES             Location/Qualifiers
     source          1..2616
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p11"
     gene            1..2616
                     /gene="Fchsd1"
                     /note="FCH and double SH3 domains 1"
                     /db_xref="GeneID:307482"
                     /db_xref="RGD:1308240"
     exon            1..46
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..2098
                     /gene="Fchsd1"
                     /note="FCH and double SH3 domains protein 1"
                     /codon_start=1
                     /product="F-BAR and double SH3 domains protein 1"
                     /protein_id="NP_001103351.1"
                     /db_xref="GeneID:307482"
                     /db_xref="RGD:1308240"
                     /translation="MQPPPRKVKPAQEVKLRFLEQLSILQTRQQREADLLEDIRSYSK
                     QRAAIEREYGQALQKLAGPFLKREGQRSGEVDSRARTVFGAWRCLLDATVAGGQTRLQ
                     ASDRYRDLAGGTGRSAKEQVLRKGTESLQQAQAEVLQSVRELSRSRKLYGQRERVWAL
                     AQEKAADVQARLNRNDHGIFHSRTSLQKLSTKLSAQSAQYSQQLRAARNEYLLNLVAT
                     NAHLAHYYQEELPALLKVLVSELSEYLRDPLTLLGHTELEAAEMILEHARHGGKAASQ
                     VNWEQDVKLFLQGPGVFSPTPPQQFQPAGTDQVHALERGAGGMAEESGLEREVQRWTS
                     RAARDYKIQHHGHRVLQRLELRRQQAPEREAPGVEQRIQEVRENIRRAQVSQVKGAAR
                     LALLQEAGLDVQRWLKPAMTQAQDEVEQERRLSEARLSQRDLSPTAEDAELSDFDECE
                     EAGELFEEPAPPALATRALPCPAHVVFGYQAGREDELTITEGEWLEVIEEGDADEWVK
                     ARNQHGEAGFVPERYLNFPDLSLPESSHGSDNPSGAEPTAFLARALYSYIGQSEEELS
                     FPEGALIRLLPRAQDGVDDGFWRGEFGGHVGVFPSLLVEELLGPPGPPELSDPEQMLP
                     SPSPPSFSPPAPTCALDRSPAPALPSDKVIDCPGPLDMMVPRLRPMRPPPPPPAKAPD
                     PGHPDPLT"
     exon            47..144
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            145..190
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            191..258
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            259..400
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            401..537
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            538..601
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            602..730
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            731..853
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            854..949
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            950..1069
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1070..1174
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1175..1336
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1465
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1466..1549
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1550..1667
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1668..1888
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1889..1976
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1977..2032
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2033..2616
                     /gene="Fchsd1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctggcagcc tttggtggaa tcgcgatgca gccgccgccc cgaaaagtga agccagccca
       61 ggaggtgaaa cttcgctttt tggagcagct gagtatcctt cagacccgac aacagaggga
      121 ggcggatcta ctggaagaca tcagatccta cagcaagcag agggcagcca ttgaacggga
      181 gtatggccag gcactccaga aactggccgg gccattcctg aagagagaag ggcagcgaag
      241 tggggaggta gacagcaggg ctaggacagt gtttggtgcc tggcgctgcc ttctggatgc
      301 cactgtggct ggaggccaaa cccgacttca ggcgtctgac cgatatcgtg acctagcagg
      361 gggtaccggg aggagtgcca aggagcaggt gcttagaaag gggacagaga gcctccagca
      421 agcacaggct gaggtgctac agtccgtccg ggagctgagc cgaagccgga agctctatgg
      481 gcagcgagag cgagtgtggg ccttggcaca ggagaaggca gccgatgtcc aggccaggct
      541 gaaccgaaat gaccatggga tcttccactc tcggaccagc ctccagaaac tgagcaccaa
      601 gctgtccgcc cagtcagccc agtattccca gcagctgaga gcagcccgca acgagtacct
      661 gctaaatttg gtggccacca atgctcacct tgcccattac taccaagagg aattgccagc
      721 actgctcaag gtcctggtaa gtgagctgtc cgagtacttg agggaccccc tgactttgtt
      781 gggacacacc gagctggaag ctgcagagat gatcctggag catgcccgcc atggggggaa
      841 ggcagcttct caggtaaact gggaacagga tgtgaagctg tttcttcagg ggcctggagt
      901 cttttctcca actccacctc agcagttcca gccagcggga actgatcagg tgcatgccct
      961 ggaacgggga gcgggaggca tggctgaaga gagtggcttg gagagagagg ttcagcgctg
     1021 gacaagcagg gctgcccggg actacaagat ccagcatcat gggcatcggg tcctgcagcg
     1081 actggagctg aggcgtcagc aggctccaga gcgagaagct ccaggcgtag aacagaggat
     1141 acaggaagtg agggagaaca tccgacgggc acaggtgagc caagtgaaag gggccgcccg
     1201 gttggccctg ctacaggagg ctggcctcga tgtgcagcgg tggctgaagc cagccatgac
     1261 ccaagcccag gatgaagtgg aacaggagcg acgacttagt gaagctcgac tttcccagag
     1321 ggacctctct cccacagctg aggatgctga gctttctgac ttcgacgaat gtgaggaggc
     1381 tggggagctc tttgaggagc ctgccccacc agccctggcc accagagccc ttccctgccc
     1441 tgcccatgta gtgtttggct atcaggcagg acgtgaggac gagctgacta tcacagaggg
     1501 tgagtggctg gaggtcatag aggaaggaga tgctgatgaa tgggttaagg ctcggaacca
     1561 gcatggtgaa gcaggctttg ttcctgaacg atatctcaac ttcccggatc tctcccttcc
     1621 tgagagcagc catggcagcg acaatccctc aggagcagag cccacagcat tcttggcacg
     1681 tgctctgtac agctacatag gacagagtga agaggagtta agttttcctg aaggggcact
     1741 catccgcctg ttgcccaggg ctcaagatgg agtggacgat ggcttctgga ggggagaatt
     1801 tggggggcat gttggagtct tcccatctct cctggtagag gaactgcttg gtcccccggg
     1861 gccacctgaa ctctctgacc ctgaacagat gctgccatcc ccttctcctc ccagcttctc
     1921 ccctcctgca cccacctgtg ccttggacag atcccctgca cctgctctgc cttctgacaa
     1981 agtcatagac tgccctggac ccctagacat gatggtgcct cgactcaggc cgatgcgtcc
     2041 accacctccc ccaccagcca aagccccgga tcctggtcat cccgatcctc tcacttgaag
     2101 gccaggagtc actgcccttc ggtgatgctg ctgcccctga ctccatgctg acagaagcca
     2161 ccccctcaat ggtctggagc gacataagca aaagctgcag tcttccccga tgtccattct
     2221 cacctccggg ggtagaaatt taccctgttc ccatttctgg gatttgaacc cacaccctcc
     2281 ccgtattgtt ctcctgccat ttctggaagt acccctttga ctttgtgcta tcaccccata
     2341 tctaaggtgg taaaacacca caaaatcttc ggggctggaa cccatctccc aaagccttgc
     2401 atggctctgg ctcatctgtg tcttcacccg gcctctgtgg tcaaccccac cctgaatgtc
     2461 agggtcagta ggcctggggc caggagagga ctttggaagt cagaaggagc tgagccagga
     2521 tgcaaagcaa ctgtaatggt ctgagcggat ttattgacag tgaataaagg gtatgaagtc
     2581 caagacaggg cttgggcctc ttgtgccaag acggca
//
