LOCUS       NM_001107600            1928 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus F-box and WD repeat domain containing 4 (Fbxw4),
            mRNA.
ACCESSION   NM_001107600 XM_001058429 XM_219944
VERSION     NM_001107600.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1928)
  AUTHORS   Ebstein F, Lange N, Urban S, Seifert U, Kruger E and Kloetzel PM.
  TITLE     Maturation of human dendritic cells is accompanied by functional
            remodelling of the ubiquitin-proteasome system
  JOURNAL   Int J Biochem Cell Biol 41 (5), 1205-1215 (2009)
   PUBMED   19028597
REFERENCE   2  (bases 1 to 1928)
  AUTHORS   Sidow A, Bulotsky MS, Kerrebrock AW, Birren BW, Altshuler D,
            Jaenisch R, Johnson KR and Lander ES.
  TITLE     A novel member of the F-box/WD40 gene family, encoding dactylin, is
            disrupted in the mouse dactylaplasia mutant
  JOURNAL   Nat Genet 23 (1), 104-107 (1999)
   PUBMED   10471509
REFERENCE   3  (bases 1 to 1928)
  AUTHORS   Crackower MA, Motoyama J and Tsui LC.
  TITLE     Defect in the maintenance of the apical ectodermal ridge in the
            Dactylaplasia mouse
  JOURNAL   Dev Biol 201 (1), 78-89 (1998)
   PUBMED   9733575
REFERENCE   4  (bases 1 to 1928)
  AUTHORS   Johnson KR, Lane PW, Ward-Bailey P and Davisson MT.
  TITLE     Mapping the mouse dactylaplasia mutation, Dac, and a gene that
            controls its expression, mdac
  JOURNAL   Genomics 29 (2), 457-464 (1995)
   PUBMED   8666395
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473986.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_219944.4, XM_001058429.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760396
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1928
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..1928
                     /gene="Fbxw4"
                     /note="F-box and WD repeat domain containing 4"
                     /db_xref="GeneID:309444"
                     /db_xref="RGD:1306518"
     exon            1..412
                     /gene="Fbxw4"
                     /inference="alignment:Splign:2.1.0"
     CDS             165..1391
                     /gene="Fbxw4"
                     /note="F-box and WD-40 domain protein 4; F-box/WD
                     repeat-containing protein 4-like"
                     /codon_start=1
                     /product="F-box/WD repeat-containing protein 4"
                     /protein_id="NP_001101070.1"
                     /db_xref="GeneID:309444"
                     /db_xref="RGD:1306518"
                     /translation="MAAAAEDGAAAVEPATRPAAGPALWRLPEELLLLICSYLDMRAL
                     GRLAQVCRWLRRFTSCDLLWRPIARASLNSGFTRLGTDLMTSIPVKERVKLSQNWRLG
                     RCRDRILLKWRYSQMPWMQLEDSSLYLSQANFILAYQFRPDGASLNRRPFRVFAGHDE
                     DVCHFVLANSHIISAGGDGKIGVHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDR
                     TAKVWPLASGQLGQCLHTIQTEDRVWSIAISPVLSSFVTGTACCGHFSPLRIWDLTSG
                     QLITHLGSDFPPGAGVLDVMYESPSTLLSCGYDTYVRYWDLRTSARKCVMEWEEPHDS
                     TFYCLQTDGNHLLATGSSYYGLVRLWDRRQRACLHAFPLTSTPLSSPVYCLRFTTRHL
                     YAALSYNLHVLDFENP"
     exon            413..508
                     /gene="Fbxw4"
                     /inference="alignment:Splign:2.1.0"
     exon            509..694
                     /gene="Fbxw4"
                     /inference="alignment:Splign:2.1.0"
     exon            695..827
                     /gene="Fbxw4"
                     /inference="alignment:Splign:2.1.0"
     exon            828..922
                     /gene="Fbxw4"
                     /inference="alignment:Splign:2.1.0"
     exon            923..988
                     /gene="Fbxw4"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1129
                     /gene="Fbxw4"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1271
                     /gene="Fbxw4"
                     /inference="alignment:Splign:2.1.0"
     exon            1272..1928
                     /gene="Fbxw4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggaagaagg gccgagacgc tccgggaggc aggatgaggg cagcgcagag ccagggaagg
       61 aggaatgtag ggttggggcc gggcggcggg aggaccacag cctggagaga gcacaagagc
      121 aggagcgtca ggcgtgcggc ggcatcccgg aaacccagac ggccatggcg gcggcagccg
      181 aggacggggc agcggctgtg gagccggcca cccgtccggc cgcggggccc gcgctctgga
      241 gactgccgga ggagctgctg ctgctcatct gctcctacct cgacatgcgg gccctcggcc
      301 gcctggccca ggtgtgccgc tggctgcggc gtttcaccag ctgcgacctg ctctggcgcc
      361 cgatagcccg ggcctcgctc aactccggct tcacgcggct cggcaccgac ctgatgacca
      421 gcattccagt aaaggaacga gtgaagctgt ctcagaactg gcggctggga cgatgccgag
      481 atcggattct actgaagtgg agatacagtc agatgccttg gatgcagcta gaagactctt
      541 ctctgtacct atctcaggct aatttcatcc tggcctacca gttccgcccg gatggtgcaa
      601 gcttgaaccg tcggcccttc agagtcttcg ctgggcacga tgaggacgtt tgtcactttg
      661 tgctggccaa ctcccatatc atcagtgcgg gaggagatgg gaagatcggt gttcataaga
      721 ttcacagcac cttcactgtc aagtactcag ctcatgaaca ggaggtgaac tgtgtggact
      781 gcaaaggcgg catcattgtg agtggctcca gggacaggac ggccaaggtc tggcctttgg
      841 cctcgggcca gctggggcag tgcttacaca ccatccagac cgaagacaga gtctggtcca
      901 ttgctatcag cccagtactc agctcttttg tgactggaac agcttgttgt gggcacttct
      961 cacctctgag aatctgggac ctcaccagtg ggcagctgat cacacatctg ggcagtgact
     1021 tccccccagg ggctggggtg ctggatgtca tgtatgagtc cccctctaca ctactgtcct
     1081 gtggttatga tacctatgtc cgctactggg acctccgcac aagtgcccgg aaatgtgtca
     1141 tggagtggga ggagcctcat gacagtacct tctactgcct acagacagac ggcaaccacc
     1201 tgctggccac agggtcctcc tactacggtc tcgtgcggct ctgggaccga cgccagcggg
     1261 cttgcctgca tgccttcccg ttgacatcga ccccactcag cagtcctgtg tactgcctgc
     1321 ggttcaccac caggcatctc tatgccgcgc tgtcttacaa cctccacgtc ttagactttg
     1381 aaaacccatg acagaccacc cctgcctatg ggctgcgcaa gtcagctact cagggacctc
     1441 tgcctggcag gtgaagtgac acctccctcc tcttcccatc cctgctgagc tcctgggtct
     1501 ctggccacca tgccctgaca cctgaagcac tgagccctgg acactgaggc cgtctctgac
     1561 gtgggccctc ttgtgctttt ttaggagatg tacttgaact taggtgtaca atagggccag
     1621 gcctgccccc agcccttcac agtactactg cagcctacgg agtgcggtca gaggctctca
     1681 ccatcccaga cagaaagaga cagttgctag aactaaggcc ggtaccagtc gcctcctcag
     1741 tcacatggta acttggccga catcttggag ctgggggctc ctatctgagg tactagtctg
     1801 gttttgcttt gaagttaagg acaaaggaaa cctgtcaggt tggggctctg ggctggctgc
     1861 tccttaggcc agttgtggga gacatgttac cattttaatt tttataaaaa taaaatgtaa
     1921 ttgttcac
//
