LOCUS       NM_001012117            2551 bp    mRNA    linear   ROD 07-JAN-2025
DEFINITION  Rattus norvegicus F-box protein 43 (Fbxo43), mRNA.
ACCESSION   NM_001012117 XM_235375
VERSION     NM_001012117.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2551)
  AUTHORS   Suzuki,T., Suzuki,E., Yoshida,N., Kubo,A., Li,H., Okuda,E.,
            Amanai,M. and Perry,A.C.
  TITLE     Mouse Emi2 as a distinctive regulatory hub in second meiotic
            metaphase
  JOURNAL   Development 137 (19), 3281-3291 (2010)
   PUBMED   20724447
REFERENCE   2  (bases 1 to 2551)
  AUTHORS   Perrard,M.H., Chassaing,E., Montillet,G., Sabido,O. and Durand,P.
  TITLE     Cytostatic factor proteins are present in male meiotic cells and
            beta-nerve growth factor increases mos levels in rat late
            spermatocytes
  JOURNAL   PLoS One 4 (10), e7237 (2009)
   PUBMED   19802389
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2551)
  AUTHORS   Madgwick,S., Hansen,D.V., Levasseur,M., Jackson,P.K. and Jones,K.T.
  TITLE     Mouse Emi2 is required to enter meiosis II by reestablishing cyclin
            B1 during interkinesis
  JOURNAL   J Cell Biol 174 (6), 791-801 (2006)
   PUBMED   16966421
REFERENCE   4  (bases 1 to 2551)
  AUTHORS   Shoji,S., Yoshida,N., Amanai,M., Ohgishi,M., Fukui,T., Fujimoto,S.,
            Nakano,Y., Kajikawa,E. and Perry,A.C.
  TITLE     Mammalian Emi2 mediates cytostatic arrest and transduces the signal
            for meiotic exit via Cdc20
  JOURNAL   EMBO J 25 (4), 834-845 (2006)
   PUBMED   16456547
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC082107.1.
            
            On Feb 11, 2005 this sequence version replaced XM_235375.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC082107.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760434
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2551
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q22"
     gene            1..2551
                     /gene="Fbxo43"
                     /note="F-box protein 43"
                     /db_xref="GeneID:315034"
                     /db_xref="RGD:1310225"
     exon            1..218
                     /gene="Fbxo43"
                     /inference="alignment:Splign:2.1.0"
     exon            219..1722
                     /gene="Fbxo43"
                     /inference="alignment:Splign:2.1.0"
     CDS             287..2281
                     /gene="Fbxo43"
                     /note="endogenous meiotic inhibitor 2"
                     /codon_start=1
                     /product="F-box only protein 43"
                     /protein_id="NP_001012117.2"
                     /db_xref="GeneID:315034"
                     /db_xref="RGD:1310225"
                     /translation="MPQKHSASHRAGSNMGSSAVTVRCPSLPDFGPTSSFKHRGPHEL
                     SETCSFSKKEKDPMLTCEHLETPRLGFPNPAVSPSPRKKSVSLRKEKEESPELCETPK
                     LRRKKCTLRRRLDLTLTLLKGDSDSQSSSLESNISHSLSLEKRLRDSTSGFPKEDNFS
                     PLVTSTVKTEDAISSSQNSRLHFSQHKTSTIDDSKDDCGLFEVECLSPIEGNDFKDSV
                     THFSDSGLSASDENTCPELLGSSGSQTTYGADVTTSVTPVSSLIAKIKFHGSQTLASS
                     AEVRDSLSTPEDSGFCSLSWDKSEDFLSDQEGSFQELQKHRGTPTVGDLVRQPKHPGR
                     LRRLPTLQEQGSQSETDDEMQVAHPSAGVRVGTASGVLESQQGSEEKSGDLTLSFKDL
                     SNTPALQLVCELFMKSKRKRFEQADDQEFSEEREEGKIARLQHVLAGLIGKKMGIERL
                     DILTELQYRNLKHILAMVLDSLTAESLYSAWNVSRNWRGIVAQDKRANRRRKLFIAQL
                     KAKAQGAAVLRVQDAATRLRLLSRLALRSVQAQAQAPNGQNEQAPAQSPWGEVLTPVA
                     SSSLTHLRSKQEQYLKVARTLFTDEALKPCPRCQSPAKYQPHKKRGLCSRLACGFDFC
                     VLCLCAYHGSEDCRRGSAKGRGSRDVLPGSAQSKRNLKRL"
     exon            1723..1825
                     /gene="Fbxo43"
                     /inference="alignment:Splign:2.1.0"
     exon            1826..2032
                     /gene="Fbxo43"
                     /inference="alignment:Splign:2.1.0"
     exon            2033..2526
                     /gene="Fbxo43"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcgggtcgg agagattccg agcgacttga ccttccctgc acgccgccgc tgcccttcca
       61 gtagcagtcg gggcgctgct gggggctccg ttcattgttg aggtttttct cttaagtggt
      121 ggttccttgg catgaacttt aaaggcaaag atgacagatt ttgttatttg gaagcctatt
      181 tactttgaca tgtcttaaga actcaaggtt gactggtgct gcttggatgc acatcacaaa
      241 ggaggaataa acttgtgtct actttgtaaa aacagagagc ttgaagatgc cccaaaagca
      301 ctcagccagc cacagagcag gaagcaacat ggggtcctct gctgtcaccg tcaggtgtcc
      361 cagcctccca gacttcggcc ccacatcctc ctttaagcat aggggccctc acgagctgtc
      421 agagacttgc agctttagta agaaagaaaa agacccaatg ctaacctgtg aacatctgga
      481 aactccacgt ctaggtttcc ctaatcctgc agtatctccc agtccaagaa agaagtctgt
      541 gtccctaagg aaggaaaagg aggaaagccc agaactttgc gagactccta aactcagaag
      601 gaaaaaatgc acactacgca ggaggctaga cttgactttg actcttctga agggggattc
      661 tgattcacaa agcagttctc tggaaagtaa tataagccac agtcttagcc tagaaaaacg
      721 tttgcgagac agcacttcag gtttcccaaa ggaagacaac tttagcccat tggtcaccag
      781 cacagtaaaa accgaggatg cgatttccag cagtcagaac tcaaggctac atttttctca
      841 gcacaagact tccaccattg atgattccaa agacgactgt ggcttatttg aagtggaatg
      901 tctgtctcca atagaaggca atgattttaa agattctgtc acacacttta gtgacagtgg
      961 tttaagtgct agtgatgaga atacatgtcc tgaacttctg ggctcctctg gtagtcaaac
     1021 aacctatggc gcagacgtga ccacatctgt cactccggta agtagtctca tagcaaaaat
     1081 caaatttcat ggaagccaaa cccttgcttc ttcagcagaa gtgagagaca gtctgtcaac
     1141 acctgaagac agtggcttct gctcacttag ctgggacaag tccgaagatt tcctctctga
     1201 ccaagagggc tcgttccaag aacttcaaaa acataggggg acccccacag ttggggacct
     1261 ggtaagacaa ccaaagcatc ctgggaggtt gagaaggctg cccactctcc aggagcaagg
     1321 ctcccagtca gagactgacg atgaaatgca ggtggcccat cccagcgctg gagtgagagt
     1381 gggcactgct tcgggtgtct tggagagtca gcagggctct gaggagaaga gtggggattt
     1441 gactttaagc tttaaggacc tgtcaaatac tccagccttg cagttggtgt gtgagctctt
     1501 tatgaaaagc aagaggaagc ggttcgagca ggcagatgac caggagttct ccgaggagag
     1561 ggaggagggg aaaatcgcca ggctgcagca cgttctcgca ggactgattg gcaagaagat
     1621 gggcatagaa cggctggaca tcctgacaga attacagtat agaaacttga agcatatcct
     1681 agctatggtt ttagattcct tgactgcaga gagtttatac agtgcttgga atgtcagcag
     1741 aaactggcgt ggaattgtgg ctcaggataa aagggcaaac aggaggagga agcttttcat
     1801 cgcacagctg aaagccaagg ctcagggggc tgctgtgtta cgtgtccagg atgctgccac
     1861 tcggctccgg cttctgagtc gcttggcctt aagatcagtg caggcccagg cccaggcacc
     1921 caatggtcag aacgagcagg caccagctca gtccccttgg ggggaagttc tgacaccggt
     1981 agcaagcagt tccctcaccc acctaagaag taaacaggag cagtatttga aggttgccag
     2041 gacactgttt actgacgaag ccttaaagcc gtgcccgagg tgccaatccc ctgctaagta
     2101 tcagccgcat aagaaaaggg ggctgtgcag ccgcctggcc tgtggctttg acttttgtgt
     2161 gttgtgtctg tgtgcttatc atgggtctga agactgtaga agagggtcag caaaggggag
     2221 aggtagcaga gacgttctcc cagggagtgc acaaagcaag cggaacttaa aacgcctctg
     2281 aagagactaa ggaaccactc ccgcgctggc ccgtgttctg tctgacttaa aattatgact
     2341 attttgaaca catgcaaatc ttcccattga taacagatgg tgatttattt cctactttgt
     2401 atatgttata ttgcacacca ttttattttc tttaaagtga tgagttttga aagaatttta
     2461 ttttaccttg tcatatcccc attttaatat tttgatgttt taaataaaga cattttaaga
     2521 ttgttaaaaa aaaaaaaaaa aaaaaaaaaa a
//
