LOCUS       NM_001108338            3794 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus F-box protein 21 (Fbxo21), mRNA.
ACCESSION   NM_001108338 XM_001080075 XM_341091
VERSION     NM_001108338.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3794)
  AUTHORS   Ebstein,F., Lange,N., Urban,S., Seifert,U., Kruger,E. and
            Kloetzel,P.M.
  TITLE     Maturation of human dendritic cells is accompanied by functional
            remodelling of the ubiquitin-proteasome system
  JOURNAL   Int J Biochem Cell Biol 41 (5), 1205-1215 (2009)
   PUBMED   19028597
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1, BC158866.1, CB715798.1, CB615901.1 and
            CB582551.1.
            
            On Oct 10, 2014 this sequence version replaced NM_001108338.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ212189.1, SRR26360172.1246045.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760393 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-35                JAXUCZ010000012.1  44266001-44266035   c
            36-1368             BC158866.1         1-1333
            1369-1616           CB715798.1         272-519
            1617-1989           CB615901.1         197-569
            1990-3224           JAXUCZ010000012.1  44232474-44233708   c
            3225-3794           CB582551.1         31-600              c
FEATURES             Location/Qualifiers
     source          1..3794
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     gene            1..3794
                     /gene="Fbxo21"
                     /note="F-box protein 21"
                     /db_xref="GeneID:360818"
                     /db_xref="RGD:1307346"
     exon            1..281
                     /gene="Fbxo21"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..1905
                     /gene="Fbxo21"
                     /codon_start=1
                     /product="F-box only protein 21"
                     /protein_id="NP_001101808.2"
                     /db_xref="GeneID:360818"
                     /db_xref="RGD:1307346"
                     /translation="MAAVAGDSAMEVVPALAEEAAAEASGPSCLVQLPGEVLEYILCS
                     GSLTALDIGRVSSTCRRLREVCQSSGQVWKEQFRVRWPSLMKHYSPTDYVNWLEEYKV
                     RQKAGLEARKIVASFSKRFFSEHVPCNGFSDIENLEGPEIFFEDELVCILNMEGRKAL
                     TWKYYAKKILYYLRQQKILNNLKAFLQQPDDYESYLEGAVYIDQYCNPLSDISLRDIQ
                     AQIHSIVELVCKTLRGINSRHPSLTFRAGESSMIMEIELQSQVLDAINYVLYDQLKFK
                     GNRMDYYNALNLYMHQVLTRRTGIPISMSLLYLTIARQLGVPLEPVNFPSHFLLRWCQ
                     GAEGATLDIFDYIYIDAFGKGKQLTVKECEYLIGQHVTAALYGVVNVKKVLQRMVGNL
                     LSLGKREGIDQSYQLLRDSLDLYLAMYPDQVQLLLLQARLYFHLGIWPEKVLDILQHI
                     QTLDPGQHGAVGYLVQHTLEHIERKKEEVGVEVKLRSEEKHRDVCYSIGLVMKHKRYG
                     YNCVIYGWDPTCMMGHEWIRNMNVHSLPHGHHQPFYNVLVEDGSCRYAAQENLEYNVE
                     PQEISHPDVGRYFSEFTGTHYIPNAELEIRYPEDLEFVYETVQNIYSAKEDTAE"
     exon            282..417
                     /gene="Fbxo21"
                     /inference="alignment:Splign:2.1.0"
     exon            418..512
                     /gene="Fbxo21"
                     /inference="alignment:Splign:2.1.0"
     exon            513..634
                     /gene="Fbxo21"
                     /inference="alignment:Splign:2.1.0"
     exon            635..781
                     /gene="Fbxo21"
                     /inference="alignment:Splign:2.1.0"
     exon            782..918
                     /gene="Fbxo21"
                     /inference="alignment:Splign:2.1.0"
     exon            919..1055
                     /gene="Fbxo21"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1235
                     /gene="Fbxo21"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1368
                     /gene="Fbxo21"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..1559
                     /gene="Fbxo21"
                     /inference="alignment:Splign:2.1.0"
     exon            1560..1717
                     /gene="Fbxo21"
                     /inference="alignment:Splign:2.1.0"
     exon            1718..3780
                     /gene="Fbxo21"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcgcgcgc tcgcgcagcg gcccctcagg tacgcggaca agatggcggc ggtagcgggg
       61 gacagcgcta tggaggtggt cccggcgctg gctgaagagg ccgcggccga ggcgtcgggc
      121 cccagctgcc tggtgcaact gccaggcgag gtgctggagt acatcctgtg cagcggctcg
      181 ctcacggcgc tcgacatcgg ccgcgtgtcc agcacctgcc gccgcctgcg cgaggtgtgc
      241 cagagcagcg ggcaggtgtg gaaggagcag ttccgggtga ggtggccctc tctgatgaag
      301 cactacagtc ccactgacta cgtcaattgg ttagaggaat ataaagttcg gcagaaagct
      361 gggttagaag cccggaagat tgtagcctcc ttctccaaac ggttcttttc agagcacgtt
      421 ccttgtaacg gcttcagtga cattgagaac cttgagggcc cagagatctt ttttgaggat
      481 gaactggtgt gcatcctaaa catggaagga aggaaagctc tgacctggaa gtactacgct
      541 aagaagattc tctactacct gcggcagcag aaaatcctca acaacctcaa ggctttcctg
      601 cagcagccag atgactacga gtcctatctt gaaggtgccg tttacatcga ccagtactgc
      661 aacccgctct ccgacatcag cctcagagac atccaggccc agatccacag catcgtggag
      721 cttgtgtgca aaaccctccg tggcatcaac agtcgtcacc cgagcctgac cttcagggca
      781 ggcgagtcct ctatgataat ggagatagaa ctccagagcc aagtgctgga cgccatcaac
      841 tatgtcctgt acgaccagct caagttcaaa gggaaccgca tggactacta caatgccttg
      901 aacctctaca tgcaccaggt attgactcgc agaacgggaa tccccatcag catgtctctg
      961 ctctacctga ccatcgcccg gcagctgggc gtccctctgg agcctgtcaa cttcccaagc
     1021 cacttcctgc tgaggtggtg ccaaggcgca gaaggggcaa ccctggacat cttcgactac
     1081 atctacatag atgcttttgg gaagggcaag caactgacag tgaaagagtg tgagtacttg
     1141 attggccagc acgtgacggc agctctctat ggcgtggtga acgtgaagaa ggtgctgcag
     1201 cggatggtgg gcaacctgct gagcctgggc aagagggaag gcattgacca gtcctaccag
     1261 ctcctcagag actccttgga cctgtacctg gcgatgtacc cggaccaggt gcagctcctg
     1321 ctcctgcaag ccaggctcta cttccacctg ggcatctggc cagagaaggt gcttgacatc
     1381 ctccagcaca tccagaccct cgaccccggg cagcacgggg cggtggggta tctagtgcag
     1441 cacacgctag agcacattga gcgcaagaag gaggaggtgg gcgtggaggt gaagctgcgc
     1501 tccgaggaga agcacaggga tgtctgctac tccatcgggc tcgttatgaa gcacaagagg
     1561 tacggctaca actgtgtgat ctacggctgg gaccccacgt gcatgatggg gcacgagtgg
     1621 atccgaaaca tgaatgtgca cagtctgcct cacggccacc atcagccctt ctacaatgtg
     1681 ctggtggagg acggctcctg cagatacgca gctcaagaaa acctggaata caacgtggag
     1741 cctcaggaaa tctcgcaccc agatgtgggg cgctacttct cggagttcac gggcacacac
     1801 tacatcccaa atgcagagct ggagatccgg taccccgagg acctggagtt tgtgtatgag
     1861 acagtgcaga acatttacag tgcaaaggag gacacagccg agtagactca ggggctgtca
     1921 catgtgtgct gctgctgctg ccgctgccgc tgccgctgcc gctgccgcct tctggggaac
     1981 agactcctga aggacgcgtg ctgccccccg gagtcagcac aggacagcca cttcaccagc
     2041 agccctggct gcctccccgg tttagacggt gtgtgttcct ccagccgcag acagcgctgc
     2101 tctccgctac actagtgaat cagttgaaag gcaccgtgtc cagtggcatg gctcgtctgc
     2161 ttgtcccgtg gtgacagtgt gtgacattct gtcttcatga ggtctcacca tccacactct
     2221 gttctctcac ccccttccca tccccgtctc atctaccttg tgtcagcgtc tcttccgata
     2281 gacggttggg ggccatgttt cctcatgtct ggaacacagg ccgctgggtc agggccaccg
     2341 ccctccacct tatgttaggt tgtgctcaga ggaaggcctg gagatggtgt cgtcagagtg
     2401 gtcagtccat ggtttttttt tgctaataca gaaacacaga tttcaagtgt tccttttttt
     2461 tttttttttt ttttaattta aattgagagg acagtgtctc cttcctttct cccccactgg
     2521 gtctgtgcac atctctgcct gttgtgagct tctgtctcgt acattggttc tccgagcaaa
     2581 tgtacagcaa tggcctttcc gagggaagtc ctccacgtcc gagtgctgct ccttttagat
     2641 gactactccc tgtttaaccc taggaatcta ctccagtatc atgagtggat cttaaggcgg
     2701 tcatgggtcc gcttcagcag tgaggcctgc agatcgaatg aaaattcctc ttaaaacttg
     2761 tacctcctgg tccccaaacc aagaaaacag gtctcttcct ctgatcagga aaatgaactg
     2821 aagaagccta accgggaaga cagacttcct gttccctgtc actcctttga gtcacggcca
     2881 gaccctccat tttgagagtg ttgggcttat cggaagagga gtgcatgctt tgggcttcaa
     2941 gctgccagtc tgaaggctcc aggacactga ctcctggatg aggtctagcc tcaggtcacc
     3001 cctggcttct gcctgatgct gtccatgagt gtgaaaggac caaaccttta ccagacccta
     3061 gtgggtcctc agacaagcgg tcccataggt aattacccat tgggccaatg gcacttctgc
     3121 cctgcgttta aaatgccatc attctagtga gtggagcttt agggtctgcc tgccggcctc
     3181 gcctgcctgc cttccgcatg tgaatcctca tccggtccaa gtgagcactc cctccattgt
     3241 ccttcagcag ccccaggatg gccgagggag accatcactt aggcagtctc tagaaggaca
     3301 ggacgctcga ggcttttgca gctgcagagg ttcctgccca gtctgtgcct caccagtcag
     3361 aaccagtcag aggcgggctc gaacttgcat ttggaaattt aactactctg agcatctgcc
     3421 tgaggttggg ggatttacac ctactcattg aaagatgaga gaaccagccc agaggactca
     3481 gacccttgca tcccagttgt aagcagccgc ggagcatgct ggaagtttcc attgctgggt
     3541 ttctgctttg gtttcctttt tccgtagaga gccatcaaag ctgagcagga tggcttccct
     3601 ccctgacctg actgtaaata atgtacgtag actgttttta aatgtgtttc ttcacgaagg
     3661 cttcgtttgg ctgagggagc ctctatcacc cgtgtaagtt ggcatttggg cactttctat
     3721 ttttctaaaa atgtgttttg gatcctgtac tctaataaat cataagtttc tttttaaaaa
     3781 aaaaaaaaaa aaaa
//
