LOCUS       NM_001415928            4454 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus F-box and leucine-rich repeat protein 19
            (Fbxl19), mRNA.
ACCESSION   NM_001415928 XM_039078415
VERSION     NM_001415928.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4454)
  AUTHORS   Xu,C., Liu,K., Lei,M., Yang,A., Li,Y., Hughes,T.R. and Min,J.
  TITLE     DNA Sequence Recognition of Human CXXC Domains and Their Structural
            Determinants
  JOURNAL   Structure 26 (1), 85-95 (2018)
   PUBMED   29276034
REFERENCE   2  (bases 1 to 4454)
  AUTHORS   Zhao,J., Wei,J., Mialki,R.K., Mallampalli,D.F., Chen,B.B., Coon,T.,
            Zou,C., Mallampalli,R.K. and Zhao,Y.
  TITLE     F-box protein FBXL19-mediated ubiquitination and degradation of the
            receptor for IL-33 limits pulmonary inflammation
  JOURNAL   Nat Immunol 13 (7), 651-658 (2012)
   PUBMED   22660580
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4454)
  AUTHORS   Ebstein,F., Lange,N., Urban,S., Seifert,U., Kruger,E. and
            Kloetzel,P.M.
  TITLE     Maturation of human dendritic cells is accompanied by functional
            remodelling of the ubiquitin-proteasome system
  JOURNAL   Int J Biochem Cell Biol 41 (5), 1205-1215 (2009)
   PUBMED   19028597
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jan 5, 2023 this sequence version replaced XM_039078415.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-859               JAXUCZ010000001.1  191789428-191790286
            860-1060            JAXUCZ010000001.1  191791397-191791597
            1061-1204           JAXUCZ010000001.1  191792769-191792912
            1205-1291           JAXUCZ010000001.1  191793044-191793130
            1292-1510           JAXUCZ010000001.1  191793210-191793428
            1511-1672           JAXUCZ010000001.1  191793921-191794082
            1673-2184           JAXUCZ010000001.1  191795090-191795601
            2185-2348           JAXUCZ010000001.1  191804243-191804406
            2349-2510           JAXUCZ010000001.1  191804489-191804650
            2511-2729           JAXUCZ010000001.1  191809262-191809480
            2730-4454           JAXUCZ010000001.1  191809590-191811314
FEATURES             Location/Qualifiers
     source          1..4454
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q37"
     gene            1..4454
                     /gene="Fbxl19"
                     /note="F-box and leucine-rich repeat protein 19"
                     /db_xref="GeneID:308999"
                     /db_xref="RGD:1310989"
     exon            1..859
                     /gene="Fbxl19"
                     /inference="alignment:Splign:2.1.0"
     exon            860..1060
                     /gene="Fbxl19"
                     /inference="alignment:Splign:2.1.0"
     CDS             884..2908
                     /gene="Fbxl19"
                     /codon_start=1
                     /product="F-box/LRR-repeat protein 19"
                     /protein_id="NP_001402857.1"
                     /db_xref="GeneID:308999"
                     /db_xref="RGD:1310989"
                     /translation="MSSSSRGPGAGARRRRTRCRRCRACVRTECGDCHFCRDMKKFGG
                     PGRMKQSCLLRQCTAPVLPHTAVCLLCGEAGKEDTVEGEEEKFSLSLMECTICNEIVH
                     PGCLKMGKAEGVINSEIPNCWECPRCTQEGRTSKDAGEGPGRRRADNGEEGANLGGGW
                     KLTEEPPPPPPLPRRKGPLPAGPPPDDVPGPPKRKEREGGNEPPTPRKKVKGGRERHL
                     KKVGGDACLLRGADPGSPGLLPPRVLNPSQAFSSCHPGLPPENWEKPKPPIASAEGPA
                     VPSPSPQREKLERFKRMCQLLERVPDTSSSSSDSDSDSDSSGTSLSEDEAPGEARNGR
                     RPARGSSGEKENRGGRRAIRPGSGGPLLSWPLGPAPPPRPPQLERHVVRPPPRSPEPD
                     TLPLAAGSDHPLPRAAWLRVFQHLGPRELCVCMRVCRTWSRWCYDKRLWPRMDLSRRK
                     SLTPPMLSGVVRRQPRALDLSWTGVSKKQLMWLLNRLQGLQELVLSGCSWLSVSALGS
                     APLPALRLLDLRWIEDVKDSQLRELLLPPPDTKPGQTESRGRLQGVAELRLAGLELTD
                     ASLRLLLRHAPQLSALDLSHCAHVGDPSVHLLTAPTSPLRETLVHLNLAGCHRLTDHC
                     LPLFRRCPRLRRLDLRSCRQLSPEACARLAAAGPPGPFRCPEEKLLLKDS"
     exon            1061..1204
                     /gene="Fbxl19"
                     /inference="alignment:Splign:2.1.0"
     exon            1205..1291
                     /gene="Fbxl19"
                     /inference="alignment:Splign:2.1.0"
     exon            1292..1510
                     /gene="Fbxl19"
                     /inference="alignment:Splign:2.1.0"
     exon            1511..1672
                     /gene="Fbxl19"
                     /inference="alignment:Splign:2.1.0"
     exon            1673..2184
                     /gene="Fbxl19"
                     /inference="alignment:Splign:2.1.0"
     exon            2185..2348
                     /gene="Fbxl19"
                     /inference="alignment:Splign:2.1.0"
     exon            2349..2510
                     /gene="Fbxl19"
                     /inference="alignment:Splign:2.1.0"
     exon            2511..2729
                     /gene="Fbxl19"
                     /inference="alignment:Splign:2.1.0"
     exon            2730..4454
                     /gene="Fbxl19"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggaaggagg aaggagctga ggagggatga gagcggcgac cagggcccgg ggccgaagca
       61 gcgcgaggct aggggagtag gggtgctaag acatcccaac tgcccccacc cccttcctgc
      121 ctctgcccca tcctttcctt ataccctccc attttaggag tggatttatt caaattttat
      181 ttaaatcctt atatcttgag ggtcgcgcgt ttgaacgggg agggcggggg cgcgtgcagg
      241 ctgggggggg cggggccgga gcagcttcct tcacccccct cagcgagccc tgtctctgta
      301 ggtcaggggg ccgcagtaca ggggcggacc caggggaggg gggcaggttg cagcgacccc
      361 cccctccccg ggaaccggcg gtgggcgggg tttgaacccc ggaaacggtg gggggcccct
      421 ggtctttccc tggacccctg ggcagttgga gctgggaagg ggccagttaa gggtcggggg
      481 ctttggggaa aggtgggggt ggggagctga gactcatacc cgggactgag tggggcccgg
      541 gcaaaagctg agcaccctgc gcccaaggag cccccgttgg cctggggggg ctgagggact
      601 gagcccccca gagcaggacc tccccctgga agggccacgc cgcagcccgt gggagggcct
      661 cgcccccggc gctccccatc tccactcgct gctgtcccgg cctccgccgg agggaggggc
      721 cgagcgccct cggggggccg tggaccccgg cgttcagagc gttccgcgcc ccgcgccgcc
      781 cggccccccc gccgccgatg gccgccgacc cgccgggagc tgccgagaag ggagagatgg
      841 ctcccgggac acgtgtgagc cttcggcgtt gctgacgccc ccaatgtcgt cgagcagccg
      901 gggaccgggg gccggagcgc gccgacgccg aacccgctgc cgtcgttgcc gggcctgtgt
      961 tcgaactgag tgcggggact gccatttctg ccgagacatg aagaagttcg gggggcccgg
     1021 gcgcatgaag cagtcgtgcc tgcttcggca gtgcaccgcg cccgtgctcc cacacacggc
     1081 tgtatgcctc ttgtgtgggg aagctgggaa ggaggataca gtggagggag aagaggagaa
     1141 atttagtttg agcctcatgg agtgtacaat ctgcaacgag atcgtccacc ctggctgcct
     1201 gaagatggga aaggctgagg gtgttatcaa ttcagagata cccaactgtt gggagtgccc
     1261 ccgatgtacc caggaaggac ggacaagcaa ggatgcaggt gagggtccag ggcgccgcag
     1321 ggctgacaat ggtgaggaag gcgctaacct agggggtgga tggaagctga cagaggagcc
     1381 gccacctcca ccacccctgc ccagaagaaa gggaccctta cctgctggcc ctccccctga
     1441 cgatgtgcct gggcccccca aacggaagga gagggagggg gggaatgagc cccccacccc
     1501 aaggaaaaag gtgaaaggag gccgagagag gcacttgaag aaggtgggtg gagatgcctg
     1561 cctcctccga ggagcggacc caggcagccc gggccttctg ccccccaggg ttctgaatcc
     1621 gagccaggca ttctcatcct gccaccctgg gctccctccc gagaactggg agaaaccaaa
     1681 gccacctata gcttctgctg agggcccagc agtgccatcc ccatcgccac agagggagaa
     1741 gctggagcgt ttcaagcgta tgtgccagct gctggaacgg gtgcctgata cctcttcttc
     1801 gtcttcggac tcagactctg attcagactc atctggcaca tcacttagtg aggatgaagc
     1861 tcccggggag gcccggaatg ggcggcggcc agcgaggggc agctctggcg agaaggagaa
     1921 ccgtggggga cggcgggcta tacgccctgg cagtggagga ccactgctca gctggcctct
     1981 gggccctgcc ccaccaccac ggcctccaca gttggagcgg catgtagtaa ggcccccacc
     2041 tcgaagcccc gagcctgaca ctctgccttt ggctgctgga tccgaccacc ctcttcctcg
     2101 ggctgcctgg cttcgtgtct tccagcacct tggaccccgg gagctatgtg tctgcatgag
     2161 agtctgccgg acttggagcc gctggtgcta tgacaagcgt ctgtggccta ggatggacct
     2221 aagccggagg aagtcactga ccccacccat gcttagtggg gtggttcgcc gccagccacg
     2281 tgctctggac ctcagctgga caggtgtctc caaaaagcag ctcatgtggc tcctgaaccg
     2341 actgcaaggc ctgcaggagt tggtgctttc tgggtgctcc tggctgtccg tctctgccct
     2401 gggctcagcc ccactgcccg ctctgcggct cttggacctc cgctggattg aagacgttaa
     2461 agactcccag cttcgggagc tgctgctgcc tccaccagac accaaaccag ggcaaacaga
     2521 gagtcgaggt cgactgcagg gggtggcaga acttcgccta gcaggcctgg agctcactga
     2581 tgcctccctg aggctcctat tgcgccacgc tccccaactc agtgccctgg atctgagtca
     2641 ctgcgcccac gtgggggacc ccagtgttca cctcctcacg gctcctactt cccctctccg
     2701 agaaacactg gtgcacctca atctcgctgg gtgccaccgc ctcacggacc actgccttcc
     2761 actgttccgt cgatgcccac gtcttcgccg cctggaccta cgctcctgcc gccagctctc
     2821 acctgaagct tgtgcccggt tggcggcggc cgggccccct ggcccctttc gctgcccaga
     2881 agagaaacta cttctcaagg acagctagtt gggtgcctat gcctccttcc cccaggactc
     2941 aacaagagaa cctggacctc ttgccttcat ttcaccccct gttgggaggc caggttattt
     3001 tcttcatgac ttggcactcc tcagtttaat gacttgggat tcttgcccag gggcttgagc
     3061 cagccttccc ttctcccacc tgcactgata tctctggggg tctttgcttc ccatctctcc
     3121 cttccatctg cttcattgtc cgtccccttg ggggagtggg tcaagaggta ctggggaggt
     3181 gctgagccaa agggatggtg ggaggggcgg tggaggtgca agtcttgagt agggaaaaat
     3241 gaggtgactt ggtatcttgc atacaggata ctggggggag ggctggggga ggtgatggat
     3301 gggtgtgggg agggcagaaa tcagaccaac aagggttcag ggaacaaaga ccagttgggt
     3361 gggatggggg accaaaaagg gaaaccagaa gagcaattgg ggatccgggt gtcaagatag
     3421 ggggctctac aaaccaggaa atgccaggac tgggggctga gagatgagca gatgtggggt
     3481 tagtagaact ctctgtgtgg ggttacctct ctccccttcc ctctacccag atttcagttt
     3541 tcccgacctt gactccttga acgtcactga aaatggcagc tattgcaagg agtaggggcc
     3601 gcgggactac ctgctgttaa gcgtggtggc ccggggagtg gtgaggggta gcccagaccc
     3661 ctgcctggct ctctacacaa tacttgaaca ttcatctgta ctgaagtgtt acttgaaccg
     3721 gggaatctcg gacttggggg agtgtgatgt aaggggacca acttgaccga gactgggcta
     3781 gtgggtaccc agtttggact gtcccacccc cagcgctctt gctttactgt gttgaacagc
     3841 tccacccttc cgacctgagt tgggggtggg ggaatgtcag cttaaagatg ggcaagatgg
     3901 gactcctcca gtttggctct tcccattctt tcatcgtcat ggaaacttgt atcctatttg
     3961 cccagggaac tgccactcct ggttgccatg gaaatagcag ccaatggaca cctccggaaa
     4021 tcagtgctaa gactggaaac ggtccctctt agttgctgtg ggaacttagt aacagactct
     4081 tggcacctcc cctctcccca cccctttcct attgccagtg tgggggtggg gtctcaagag
     4141 cctgagggag gagtcgggtc taggtcccac tcaggccagg ggaaactgga ttgtaccaca
     4201 tgggggtggg ggggagggga atctatccac atacctcagg taacaggaag gtgcgcgggt
     4261 tgggggtggg ggctgggcgg accaaaggca ggaggggggg gcctggggtt ggagaaaggc
     4321 ttgatgatgg ggccgcttgc gggaggggag gaggcacccc ggcaaggggc aagtggggca
     4381 cccagccggg ctggacccct aaccccacaa gtctgtacaa taaggtttgc tataaaactc
     4441 agaatctagc cggg
//
