LOCUS       NM_001107603            1346 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus F-box and leucine-rich repeat protein 15
            (Fbxl15), mRNA.
ACCESSION   NM_001107603 XM_001066947 XM_347194
VERSION     NM_001107603.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1346)
  AUTHORS   Cui,Y., He,S., Xing,C., Lu,K., Wang,J., Xing,G., Meng,A., Jia,S.,
            He,F. and Zhang,L.
  TITLE     SCFFBXL(1) regulates BMP signalling by directing the degradation of
            HECT-type ubiquitin ligase Smurf1
  JOURNAL   EMBO J 30 (13), 2675-2689 (2011)
   PUBMED   21572392
  REMARK    GeneRIF: FBXL15 is a key regulator of BMP signalling during
            embryonic development and adult bone formation.
            Erratum:[EMBO J. 2011;30(13):2748]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1346)
  AUTHORS   Ebstein,F., Lange,N., Urban,S., Seifert,U., Kruger,E. and
            Kloetzel,P.M.
  TITLE     Maturation of human dendritic cells is accompanied by functional
            remodelling of the ubiquitin-proteasome system
  JOURNAL   Int J Biochem Cell Biol 41 (5), 1205-1215 (2009)
   PUBMED   19028597
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473986.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_347194.3, XM_001066947.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ235302.1, SRR8487227.72574.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1346
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..1346
                     /gene="Fbxl15"
                     /gene_synonym="RGD1306444"
                     /note="F-box and leucine-rich repeat protein 15"
                     /db_xref="GeneID:309453"
                     /db_xref="RGD:1306444"
     exon            1..344
                     /gene="Fbxl15"
                     /gene_synonym="RGD1306444"
                     /inference="alignment:Splign:2.1.0"
     CDS             292..1194
                     /gene="Fbxl15"
                     /gene_synonym="RGD1306444"
                     /note="F-box only protein 37"
                     /codon_start=1
                     /product="F-box/LRR-repeat protein 15"
                     /protein_id="NP_001101073.1"
                     /db_xref="GeneID:309453"
                     /db_xref="RGD:1306444"
                     /translation="MEPPMEQSGGEQEPGAVRLLDLPWEDVLLPHVLNWVPLRQLLRL
                     QRVSRAFRALVQLHLARLRRFDAAQVGPQIPRAALVRLLRDAEGLQELALAPCHEWLL
                     DEDLVPVLARNPQLRSVALAGCGQLSRRALGALAEGCPRLQRISLAHCDWVDGLALRG
                     LADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDTAVQELARNC
                     PQLEHLDLTGCLRVGSDGVRTLAEYCPALRSLRVRHCHHVAEPSLSRLRKRGVDIDVE
                     PPLHQALVLLQDMAGFAPFVNLQV"
     exon            345..498
                     /gene="Fbxl15"
                     /gene_synonym="RGD1306444"
                     /inference="alignment:Splign:2.1.0"
     exon            499..1004
                     /gene="Fbxl15"
                     /gene_synonym="RGD1306444"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1346
                     /gene="Fbxl15"
                     /gene_synonym="RGD1306444"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caccactcag aggcggctac cggcccgcaa cgaagaccga aagcagtctt cgctcgccgc
       61 tactccagcc tcgggcttca agccctgtag ctgagaagac aactaatggt gcatcactgg
      121 tctgttctgc ctcagtttcg gggtccatcc agaaagcttc ccgataagga ttctcagtga
      181 gaccgcactc gattaaatcg gtctgtctct tcagaccaag gaggcgggtt cgccgcagcc
      241 gcttcaaggc caaagctagt aaagcttact gcgcacgcgc agtatacagc gatggagcca
      301 ccaatggagc agtccggagg ggagcaagaa ccaggagccg tcaggctcct ggacctgccc
      361 tgggaagacg tgctgctccc gcacgtcctg aactgggtcc cgctgcgcca gctgctccgg
      421 ctgcagcgcg tcagtcgcgc cttccgggcg ctcgttcagc tgcacctggc taggctgcgc
      481 cgctttgacg ccgctcaggt gggtccacag attccacggg ccgcactagt ccggctactg
      541 cgagatgctg aggggttgca ggagctggcg ctggctccgt gtcacgaatg gctgttggac
      601 gaggacctgg tgccggtgct ggcacggaat ccacagctac ggagcgtagc actggccggc
      661 tgcggccaac tgagtcgccg agcactcgga gcgctggctg agggctgccc gcgtctgcag
      721 cgcatttcgc tcgctcactg tgactgggtg gacgggctgg cactgcgtgg ccttgctgac
      781 cgctgcccgg ctctggagga gctagacctc accgcctgtc gtcaactcaa ggacgaggcc
      841 atcgtgtacc tggcgcagag acgcggcgcg ggcctccgca gcctctcgtt ggcagtcaac
      901 gccaatgtgg gggacaccgc ggtccaagag ttggctcgaa actgcccgca actcgagcac
      961 ctagacctca ccggctgcct tcgggtcgga agcgacggtg tcaggacact ggcggagtac
     1021 tgcccggcgt tgcgctctct gcgggtgcgg cactgccacc atgtggccga gcccagcctg
     1081 agccgcttgc ggaagcgtgg tgtggacatc gacgtggagc caccgctgca ccaggccctg
     1141 gtgctactcc aggacatggc tggcttcgca ccctttgtca acctacaggt ctgactgact
     1201 ttccttgggt gggagcacag ctggactgtg tagatggagc ttgatactga gccgtaggga
     1261 aactgaactg tggggcctgc ggttgagagg cctgggatag ccctgtccca ccctggaatt
     1321 tcaaataaag agctttttac cccttc
//
