LOCUS       NM_001399819            1903 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus F-box and leucine-rich repeat protein 12
            (Fbxl12), transcript variant 1, mRNA.
ACCESSION   NM_001399819 XM_006242639
VERSION     NM_001399819.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1903)
  AUTHORS   Ebstein,F., Lange,N., Urban,S., Seifert,U., Kruger,E. and
            Kloetzel,P.M.
  TITLE     Maturation of human dendritic cells is accompanied by functional
            remodelling of the ubiquitin-proteasome system
  JOURNAL   Int J Biochem Cell Biol 41 (5), 1205-1215 (2009)
   PUBMED   19028597
REFERENCE   2  (bases 1 to 1903)
  AUTHORS   Winston,J.T., Koepp,D.M., Zhu,C., Elledge,S.J. and Harper,J.W.
  TITLE     A family of mammalian F-box proteins
  JOURNAL   Curr Biol 9 (20), 1180-1182 (1999)
   PUBMED   10531037
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Nov 9, 2022 this sequence version replaced NM_001399819.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.712672.1,
                                           SRR26360190.563107.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676809 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-394               JAXUCZ010000008.1  27457379-27457772   c
            395-467             JAXUCZ010000008.1  27457200-27457272   c
            468-1903            JAXUCZ010000008.1  27453042-27454477   c
FEATURES             Location/Qualifiers
     source          1..1903
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     gene            1..1903
                     /gene="Fbxl12"
                     /note="F-box and leucine-rich repeat protein 12"
                     /db_xref="GeneID:313782"
                     /db_xref="RGD:1305528"
     exon            1..394
                     /gene="Fbxl12"
                     /inference="alignment:Splign:2.1.0"
     CDS             309..1289
                     /gene="Fbxl12"
                     /note="isoform 1 is encoded by transcript variant 1;
                     F-box/LRR-repeat protein 12"
                     /codon_start=1
                     /product="F-box/LRR-repeat protein 12 isoform 1"
                     /protein_id="NP_001386748.1"
                     /db_xref="GeneID:313782"
                     /db_xref="RGD:1305528"
                     /translation="MATLFDLPDLVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLW
                     RHVDLTLYTMRPKVMWHLLRRYMASRLHSLRMGGYLFSGSQAPQLSPALMRALGQKCP
                     NLKRLCLHVADLSMVPITSLPSTLRTLELHSCEISMIWLQKEQDPTVLPLLECIVLDR
                     VPAFRDEHLQGLTRFRALRSLVLGGTYRVTETGLDSSLQELSYLQRLEVLGCTLSADS
                     TLLAISRHLRDVRKIRLTVGGLSAQGLVFLEGMPVLESLCFQGPLITPEMPTPAQIVS
                     SCLTMPKLRVLEVQGLGWEGQEAEKVLCKGLPHCLVIVRACPKESMDWWM"
     exon            395..467
                     /gene="Fbxl12"
                     /inference="alignment:Splign:2.1.0"
     exon            468..1903
                     /gene="Fbxl12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttcgtcttc ccctggcctg gccacgcctc gtgccccctc ctctcccaag ccacatctag
       61 gttttcctat ttccagttcc atccgctagt caagctagtc aggcctagtc agtctctagt
      121 ctggtcctcc aaacggtcgt caggccgcgc cagtacagtc ctggggcctc aggcactttc
      181 ctaggaaggt agggatcctc ggcaggcctc ggaaagtcgc gccggtttgg ccagtccggc
      241 cacctcagca ccctccaggg agcgcggcct cccggccacc ggaaacggaa gcgcgcgacg
      301 gctggaccat ggcgacgctg tttgacctcc cagacttggt gctcttggag atcttctctt
      361 acctccctgt ccgggaccgg atccgcatct ccagggtctg tcaccgctgg aagaggctag
      421 tggatgaccg gtggctgtgg cgacacgtcg acctgacgct ctacacgatg cggccgaaag
      481 tcatgtggca cctcctgcgc cggtacatgg cgtcccggct ccactcgttg cgcatgggcg
      541 gctacctatt ctctggctct caggccccac agctgtcccc tgccttgatg cgggccctgg
      601 gccagaaatg ccccaacctg aagcgcctgt gcttgcatgt ggctgacctg agtatggtgc
      661 ctatcaccag cctgcctagc acactgagga ccctggagct gcacagctgc gaaatctcga
      721 tgatctggtt gcagaaagag caggacccca cggtgctgcc actgctggaa tgcatcgtgc
      781 tagaccgagt gccggccttc cgtgatgagc accttcaggg ccttacccgc ttccgagccc
      841 tgcgctcgct ggttctgggt ggcacctacc gggtcactga gaccgggcta gattccagcc
      901 tgcaggagct gagctacctg caaaggctgg aggtgctggg ctgcaccctg tcagcagaca
      961 gcaccttgct ggccatcagc cgccacctcc gagatgtgcg caagattcgg ctgaccgttg
     1021 gaggcctctc agctcagggc ctggtgttcc tggagggaat gccggtcctg gagagtttgt
     1081 gcttccaggg tccccttatc accccagaaa tgcccacacc cgctcagatt gtgtcctcct
     1141 gcctcaccat gcctaagctc agagtgcttg aggtgcaggg gctgggctgg gagggccagg
     1201 aagcagagaa ggtcctgtgc aagggcctgc cccactgcct agttatcgtc agagcttgtc
     1261 ccaaagaatc catggactgg tggatgtgag ggcatcaccc gtccgtctct gggacctatc
     1321 ctaacattga aagtgacttt ccaagcaaac tgaagcatgt aaattaatga gggactgagg
     1381 tctcaaggaa aggaagctag gaccttgggg cttcctgagc tggggttatc tgtaatctgg
     1441 gtgacctcag acttgtctta caagagtctg gaaggcccag ttcacacatt taggaatagg
     1501 catcatagct acctcatgat tcatttttaa gtccttaccc tcctttttcc ccccagtacc
     1561 tgaggatcaa acccatgacc ttaggtatgg tagacaagca gtattgtgct gctgagccac
     1621 actggagccc tgggaagcct taacagaccc cacaagaccc ttatagaggg tcatttcagg
     1681 aatggtcagg tgagggtgaa gggggttcag ggctctaagg tctgtctggt ttctcccttc
     1741 atggttgaga ggcatggagg tcgggcaggg gagccaggtg gctggactgt cctagttttc
     1801 taaaaggttc tcaatcatat ttactgtgtt ttatatcctg cctttttcat gttttctaca
     1861 gcatatacta ttttactatt aaagaaaaag gatgtttttc aaa
//
