LOCUS       XM_006236922            4514 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus fibulin 2 (Fbln2), transcript variant
            X1, mRNA.
ACCESSION   XM_006236922
VERSION     XM_006236922.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jan 17, 2024 this sequence was replaced by
            NM_001100490.1.
            
            On Aug 7, 2014 this sequence version replaced XM_006236922.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4514
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4514
                     /gene="Fbln2"
                     /note="fibulin 2; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 33 ESTs, 5
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 42 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:282583"
                     /db_xref="RGD:628685"
     CDS             290..3955
                     /gene="Fbln2"
                     /codon_start=1
                     /product="fibulin-2 isoform X1"
                     /protein_id="XP_006236984.1"
                     /db_xref="GeneID:282583"
                     /db_xref="RGD:628685"
                     /translation="MLLQESAGVWLALALVTALTLSPSMGVPWQDCTGAECPPLENCI
                     EEALEPGACCATCVQQGCACEGYQYYDCVQGGFVDGRVPAGQSYFVDFGSTECSCPPG
                     GGKISCQFMLCPELPPNCIEAVVVADSCPQCGQVGCVHSGRKYAAGHTVHLSSCRACH
                     CPDAGGELICYQLPGCHGNFSDAEEGDSERQYEDPYSYDQEVAEAEATVAIVNEVQAG
                     AEGPPAALGGGNLPPSSIRVTPWPVALPRPTAAAALGPPAPVQAKARRVTLDIDEEEE
                     EEVEEILATEPPVAGSPGRLDSLPTTSPARPGLPVQEKEAEAKAGPEENLIPEAQATS
                     RSVTQEGAAPLPKSGLAGLSPSLATDSSSEDALKSSSQPTLSTLPPDRAQVSPSPETP
                     EEIPQRPQLLPRSRAEEDTDPNSVHSVPRGDPDGSTKDLVETCCAAGQQWAIDNDECQ
                     EIPENGAQSDVCRIAQRHCCISYLKEKSCVAGVMGAKEGETCGAEDNDTCGVSLYKQC
                     CDCCGLGLRVRAEGQSCESNPNLGYPCSHVMLSCCEGEEPLIVPEVRRPPEPGATPRR
                     VSETEMGSREALSLGTEAELPNSLPGDDQDECLMLPGELCQHLCINTVGSYRCACFPG
                     FELQGDGRTCRPDGGAPQLDTARESAPRSESAQVSPNTIPLPVPQPNTCKDNGPCRQV
                     CRVIGDTAMCSCFPGYAIMADGVSCEDQDECLMGTHDCSWKQFCVNTLGSFYCVNHTV
                     LCAEGYILNAHRKCVDINECVTDLHTCTRAEHCVNTPGSFQCYKALTCEPGYVLTDGE
                     CTDVDECVTGTHNCQAGFSCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLLE
                     PCRSGFSCINTVGSYTCQRNPLVCRRGYHANEEGSECVDVNECETGVHRCGEGQLCYN
                     LPGSYRCDCKPGFQRDAFGRTCIDVNECWISPGRLCQHTCENTPGSYRCSCAAGFLLA
                     ADGKHCEDVNECETRRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGIL
                     CTFRCVNVPGSYQCACPEQGYTMMANGRSCKDLDECALGTHNCSEAETCHNIQGSFRC
                     LRFDCPPNYVRVSETKCERTTCQDISECQTSPARITHYQLNFQTGLLVPAHIFRIGPA
                     PAFAGDTISLTITKGNEEGYFVTRRLNAYTGVVSLQRSVLEPRDFALDVEMKLWRQGS
                     VTTFLAKMYIFFTTVAP"
ORIGIN      
        1 agccagagcc tagagagggg gagtggaaag ggggctcaga gaccaggaca ggagagctca
       61 ggctccaggg cgggttgagc cttgggttgg gtgaagtctt agcaatccaa ggccccgccc
      121 caaggcggga cccgtggggc ggggtctcaa ggcctggctt gtcccgctct tctccacccg
      181 gcgccgcgcg ccaccagggc tctggattca ccgacggcgg gtgcaaggac agactgaccg
      241 cggcgcagct caacacagag cacggagtac agaggcctct tgagacacga tgctgctcca
      301 ggaatctgca ggagtgtggc tggcattggc tctggtcaca gctctgactc tgagcccaag
      361 catgggcgtc ccgtggcagg actgcacagg ggccgagtgt ccaccgctgg agaactgcat
      421 tgaggaggcg ttggagccag gagcctgctg tgctacctgt gtgcagcagg gctgtgcctg
      481 tgagggctac cagtactacg actgtgtaca gggaggtttt gtggatggcc gtgtacccgc
      541 cggccagtcc tactttgtgg actttggcag caccgagtgc tcctgcccac cgggtggtgg
      601 taagatcagc tgccagttta tgctgtgccc tgagctacca cccaactgca ttgaggctgt
      661 ggtagtagct gacagctgcc cgcagtgcgg tcaggtgggc tgtgtccaca gtggccgtaa
      721 gtacgctgct ggccacactg tccacctctc atcctgccgg gcctgccact gtcccgacgc
      781 tggtggtgag ctcatttgct accagcttcc tggttgccat ggtaacttct cagatgctga
      841 ggaaggtgac tctgagaggc aatatgaaga cccttacagc tatgaccagg aggtggctga
      901 ggcagaagct actgtggcca ttgtgaacga ggtccaggca ggtgcagaag gccccccagc
      961 tgctctggga ggtggaaatc tgccaccatc ctccatccga gtaaccccct ggccagttgc
     1021 cctccccaga cccacggcag ctgctgccct gggtcctcca gcacctgtgc aggccaaagc
     1081 caggagagtg acattggaca ttgatgagga agaggaggaa gaagtggagg agatactagc
     1141 caccgaaccg ccagtagcag gtagtcccgg aaggctggac agcttgccca caacatcccc
     1201 agccagacct ggtctccctg tccaggagaa ggaggctgaa gccaaggcag ggcctgagga
     1261 aaacctcatt cctgaggccc aggccacttc tcgaagtgtc acacaggagg gtgctgcacc
     1321 tctgcctaag tcaggcctgg ctggtctcag tccgtctctg gccactgaca gctcttcaga
     1381 ggatgcactg aagtccagca gtcagcccac tctatctaca ctgccacctg accgagccca
     1441 ggtctcaccc tctccagaga cgcctgaaga aataccccag cgtccgcagt tgctacctcg
     1501 atcccgagca gaagaagaca cagaccccaa ctcagtacat tctgtcccca gaggtgatcc
     1561 tgatggctcc accaaggacc tggtcgagac atgctgtgca gcgggccagc agtgggccat
     1621 cgacaatgat gagtgccagg agatccctga gaatggcgcg cagagcgacg tctgcaggat
     1681 agcccagagg cactgctgca tctcctactt gaaagagaag agctgtgtgg ccggcgtcat
     1741 gggggccaag gagggtgaga cctgtggagc cgaggacaat gatacctgtg gggtctccct
     1801 gtacaagcaa tgctgtgact gctgtggcct gggactccgt gtgcgggctg agggccagtc
     1861 gtgtgagtcc aaccccaacc tgggctatcc ctgcagccac gtcatgctct cctgctgtga
     1921 aggcgaggag cctctcatag tgcctgaggt ccgccggcca ccagagcctg gggccactcc
     1981 tcgcagagtt tcagagacgg agatgggaag ccgggaggcc ttgtcactgg gcacagaggc
     2041 tgaactgccc aatagcctgc cgggagatga ccaggatgag tgcctgatgc tccctgggga
     2101 gctttgccag catctttgca tcaacactgt tggctcctac cgctgtgcct gcttccctgg
     2161 attcgagctg cagggtgatg gccgcacctg ccgcccagat ggaggtgccc cacagttgga
     2221 cactgcacga gagtctgcac cgaggtctga gtctgcccag gtatctccca acaccatccc
     2281 cctgccagtg ccacagccca atacctgcaa agacaatggg ccctgccggc aggtgtgtcg
     2341 cgttattggc gacacagcca tgtgctcctg cttccctggc tacgccatca tggcagatgg
     2401 tgtgtcctgt gaagaccaag acgagtgttt gatgggcact cacgattgta gctggaaaca
     2461 gttctgtgtg aacaccctgg gatccttcta ctgtgtcaac cacacagtgc tgtgtgcaga
     2521 gggttatatc ctcaacgcac ataggaagtg tgtggacatc aatgagtgtg tgacggacct
     2581 gcacacgtgc acccgggccg agcactgcgt gaacacgcca ggctccttcc aatgctacaa
     2641 ggctcttacc tgtgagccag gatacgttct cacagatggc gagtgcaccg acgtggacga
     2701 gtgcgtgaca ggcacgcaca actgccaggc aggcttctca tgccagaaca ccaagggttc
     2761 cttctactgc caggcccggc agcgctgcat ggatggcttc ttgcaggatc ccgagggcaa
     2821 ttgcgtagac atcaatgagt gcacatcgtt actggagcct tgccgctcag gattcagctg
     2881 catcaacacg gtgggctcct acacgtgtca gaggaaccca ctggtctgca ggcgtggtta
     2941 ccatgctaac gaggagggct ctgaatgcgt ggatgtgaat gagtgtgaga caggtgtgca
     3001 ccgctgtggt gagggccaat tgtgttacaa cctccctgga tcctaccgct gtgactgcaa
     3061 gcccggcttc cagagggatg catttggcag gacctgcatt gatgtgaatg aatgctggat
     3121 ctcgccgggt cgcctgtgcc agcacacatg tgagaacaca ccgggctcct accgctgctc
     3181 ctgtgctgct ggcttccttt tggctgcaga tggcaagcat tgtgaagatg tgaatgaatg
     3241 cgagactcgg cgctgcagcc aggagtgtgc caacatctac ggctcctatc agtgctactg
     3301 ccgccagggc taccagttgg cagaggatgg gcacacctgc acagacatcg atgagtgtgc
     3361 acagggcgct ggcattctct gtaccttccg ctgtgtcaac gtgcccggga gctaccagtg
     3421 tgcatgccca gagcaggggt acactatgat ggccaacgga aggtcctgca aggacctgga
     3481 tgagtgtgca ctgggcaccc acaactgctc tgaggctgag acctgtcaca acatccaggg
     3541 tagtttccgc tgtctgcgct tcgattgtcc accaaactat gtccgtgtct cagaaacgaa
     3601 gtgcgagcgc accacgtgcc aggatatctc ggagtgtcaa acctcaccag ctcgtatcac
     3661 gcactaccag ctcaatttcc agacaggcct actggtacct gcccatatct tccgcatcgg
     3721 ccctgctccc gcctttgctg gggacaccat ctcactgacc atcaccaagg gtaacgaaga
     3781 gggttacttt gtcacgcgca gactcaacgc ctacactggt gtggtatccc tgcagcggtc
     3841 tgttctggag ccacgggact ttgccctgga cgtagagatg aaactgtggc gccagggctc
     3901 tgtcaccacc ttcctggcca agatgtacat cttcttcacc actgttgccc cgtaaggtga
     3961 catgtcaggc aatccctcca agtggtgggc gtctgggctg tgggcagccg tgccactcct
     4021 aagtggcttt ttgctgtgac tctgtaactt aacttaatca tgctgacctg attggtcttg
     4081 agtctctcca ccttggaggg agggaaatgc accccaacag gcactgagta caggccaagg
     4141 tctcctgagg cgggatgatg gctggcaaac tggaaacagc catagggggc ttctgaatgc
     4201 cactcctcac ctatggctaa agctgacact ccattcctgc ttccactgtg ttcttcaatt
     4261 aaaaaaaatc agctgtgcat ggtagcacag acctttaatc ccagtactgg agaggcagag
     4321 gtaggtagat ttctgggagt tccgggctaa cctggtctac actgggagtt ctaaccggcc
     4381 agagctatat agaccctgtc tcaaaaagga aaaaagaaaa aaaataattt taaaagtttt
     4441 ttttgccgtt gttgtttaat gataagaata gtgcacatac attattaaaa atgatcaaat
     4501 agcacgaaag gtca
//
