LOCUS       NM_001082574            2286 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus FAST kinase domains 3 (Fastkd3), mRNA; nuclear
            gene for mitochondrial product.
ACCESSION   NM_001082574 XM_001058032 XM_214418
VERSION     NM_001082574.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2286)
  AUTHORS   Boehm,E., Zornoza,M., Jourdain,A.A., Delmiro Magdalena,A.,
            Garcia-Consuegra,I., Torres Merino,R., Orduna,A., Martin,M.A.,
            Martinou,J.C., De la Fuente,M.A. and Simarro,M.
  TITLE     Role of FAST Kinase Domains 3 (FASTKD3) in Post-transcriptional
            Regulation of Mitochondrial Gene Expression
  JOURNAL   J Biol Chem 291 (50), 25877-25887 (2016)
   PUBMED   27789713
REFERENCE   2  (bases 1 to 2286)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 2286)
  AUTHORS   Simarro,M., Gimenez-Cassina,A., Kedersha,N., Lazaro,J.B.,
            Adelmant,G.O., Marto,J.A., Rhee,K., Tisdale,S., Danial,N.,
            Benarafa,C., Orduna,A. and Anderson,P.
  TITLE     Fast kinase domain-containing protein 3 is a mitochondrial protein
            essential for cellular respiration
  JOURNAL   Biochem Biophys Res Commun 401 (3), 440-446 (2010)
   PUBMED   20869947
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CK359441.1 and
            BC079475.1.
            
            On or before Mar 11, 2007 this sequence version replaced
            XM_001058032.1, XM_214418.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760400,
                              SAMN16676786 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-242               CK359441.1         1-242
            243-2286            BC079475.1         1-2044
FEATURES             Location/Qualifiers
     source          1..2286
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p11"
     gene            1..2286
                     /gene="Fastkd3"
                     /gene_synonym="RGD1309729"
                     /note="FAST kinase domains 3"
                     /db_xref="GeneID:290946"
                     /db_xref="RGD:1309729"
     exon            1..19
                     /gene="Fastkd3"
                     /gene_synonym="RGD1309729"
                     /inference="alignment:Splign:2.1.0"
     exon            20..1474
                     /gene="Fastkd3"
                     /gene_synonym="RGD1309729"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..2019
                     /gene="Fastkd3"
                     /gene_synonym="RGD1309729"
                     /note="FAST kinase domain-containing protein 3,
                     mitochondrial"
                     /codon_start=1
                     /product="FAST kinase domain-containing protein 3,
                     mitochondrial precursor"
                     /protein_id="NP_001076043.1"
                     /db_xref="GeneID:290946"
                     /db_xref="RGD:1309729"
                     /translation="MAFTLRRAFCHMSVFWMPGAVVALKIHPANNVQKAVRDCLRVWF
                     CSLQPDLFRVRFYHAYCKSFHSENGNDLHPVGEPWFSQAQVWNQPEQTLKNEDEEMLS
                     RRLNSFASFEEVLSFIHTLDTLPVTLASAALLRICEIGKRDDEQRLPKEVLENRVFQA
                     LCLRCERDPSHLTNAVLVTVLQSLVIDPQSSLVLSLVAECQRRLRRGSLEVHHLCVLG
                     ESLARLQGASCEILKLVICQLQSENLETFAPEDIVSVYRILQACPEEVDKHQTFLNTV
                     NNFSLSIVSYLSPKSISHVLTALVALDQTHARPLLIKLGKSVVRYIPRFTNEELRQVL
                     EAFVYFGHSDRFFTEALEQHVAAQCFSLDPAVASSVMEYCSRKRILSKPIFDVVAEIF
                     VCQSEKFSPSQISELIEPFGKLNYLPPNAPALFRKVENVLFAHLRHFPPKMLLRLLHS
                     CSLIERHPVNFMSKIFSPFFLQRLQGKESYLDRLSLAQMTQLFLTSVLECPFYKGPKL
                     LPKYQVKSFLTPCCSLETPMDLHLYKSVVIGLIDLLGSRLYFASKVLTPYYYTIDVEI
                     KLDEDGFVLPFTVDEDVHTRVALCIDGPQRFCLGSKHLLGKEAIKQRHLRLLGYQVVQ
                     VPYHELELLTSRLELVDYLQRKLFSQSSTVHW"
     exon            1475..1560
                     /gene="Fastkd3"
                     /gene_synonym="RGD1309729"
                     /inference="alignment:Splign:2.1.0"
     exon            1561..1735
                     /gene="Fastkd3"
                     /gene_synonym="RGD1309729"
                     /inference="alignment:Splign:2.1.0"
     exon            1736..1805
                     /gene="Fastkd3"
                     /gene_synonym="RGD1309729"
                     /inference="alignment:Splign:2.1.0"
     exon            1806..1920
                     /gene="Fastkd3"
                     /gene_synonym="RGD1309729"
                     /inference="alignment:Splign:2.1.0"
     exon            1921..2264
                     /gene="Fastkd3"
                     /gene_synonym="RGD1309729"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgtggctcgg agccgctcgg ctaagtcacg tgtggtgaac cctatggcat ggcgttcacc
       61 ctgcggaggg ccttttgtca tatgtctgtt ttttggatgc ccggagctgt ggttgctctg
      121 aaaattcacc ctgccaataa tgtccaaaag gcagtcagag attgcctccg tgtttggttc
      181 tgctccctac aacctgatct gttcagggtc agattctatc atgcatactg taaaagcttc
      241 cactcagaaa acggaaatga ccttcatcca gtcggtgagc catggttctc tcaagcacag
      301 gtatggaacc agccagaaca gactcttaaa aatgaggatg aagagatgct ttccaggagg
      361 ctaaacagct tcgcctcctt tgaggaagtg ttgagtttca tccatacact ggacaccctg
      421 cctgtcactc tggcatcagc agctctgctc aggatttgtg agatagggaa aagagatgat
      481 gagcagagac tacccaaaga agtactggaa aaccgcgtct tccaggcttt gtgccttcgc
      541 tgtgagcggg atccctcaca tctgaccaat gctgttttgg tgaccgtttt gcagtctctg
      601 gttatagatc ctcaaagtag cctggtgctg agccttgtgg cagaatgcca gcgccggctg
      661 cgaagaggca gtctggaagt ccaccatctt tgtgttcttg gggaaagtct ggctaggctt
      721 caaggtgcaa gttgtgagat cctgaaactg gttatctgtc aactgcaaag tgaaaatttg
      781 gaaacatttg ctccagagga tatcgtgtcc gtttatagga ttctgcaggc gtgtcctgaa
      841 gaagtagaca aacatcagac atttttaaac accgtaaaca acttctccct ttcaatagtt
      901 tcctacctga gccctaaatc cattagccat gttcttactg ccttagtggc cctggaccag
      961 actcacgcac gcccactgct tataaagctg ggcaagtccg ttgtgagata cattccccgt
     1021 tttactaatg aggagctcag gcaagtcttg gaggcatttg tttattttgg acacagtgac
     1081 aggtttttca cagaggcctt agagcaacat gttgctgccc agtgcttctc cctggacccc
     1141 gccgttgcca gctctgtgat ggagtactgc agtagaaagc ggattctttc caagcccatc
     1201 ttcgatgtag ttgcagagat ttttgtttgt cagtccgaaa agttttcacc aagtcagatt
     1261 tctgaattaa ttgagccatt tggaaaactc aattatttac caccaaatgc ccctgctctg
     1321 tttaggaagg tagaaaatgt gctctttgct catttacgtc attttccacc caagatgcta
     1381 ttgaggcttc ttcactcatg ttcactgatt gagcgccatc cggtcaactt tatgtcaaaa
     1441 atattcagcc cctttttcct tcaacggctg caaggtaaag agtcatattt ggacagactg
     1501 agcctggcac agatgaccca acttttccta acctctgtcc tagagtgtcc tttctataag
     1561 ggccccaaac tccttcctaa atatcaagtg aagtcattcc tcactccatg ctgctccctg
     1621 gagacgccca tggatctcca tctttataag tctgtggtga ttggactgat tgatctttta
     1681 ggatcaagat tgtattttgc ttcaaaagtg ttgacaccct attattatac catagatgtt
     1741 gaaattaaat tagatgaaga tggatttgta ttgccattta cagtggatga ggatgtccat
     1801 acaagggtgg ccctgtgtat tgatggccca cagcgatttt gcttgggcag taaacactta
     1861 cttggaaaag aggccattaa acaaagacac ctgcggttac ttggttacca ggttgttcag
     1921 gttccctatc atgagctgga gctgcttaca tcaagacttg agttggtgga ctatttacaa
     1981 agaaagctct tttctcaaag ctccacagtc cactggtaac agaggaaact ggcttcagga
     2041 ttcacagtga aaaaagattt tatttgtaag agagtttaat ttgtgaatta gccactatat
     2101 ggaaattatg tttacagact tgggatctga aaagggtctg tgtcttttct tataccatgt
     2161 atatgtgtat tggtggtaaa tttgaaatta atttaatggc gtcttagatg ccttcactgc
     2221 agagcaggat cattcaaatg caataaaata atgtaacaag taaaaaaaaa aaaaaaaaaa
     2281 aaaaaa
//
