LOCUS       NM_001024237            1839 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus phenylalanyl-tRNA synthetase subunit alpha
            (Farsa), mRNA.
ACCESSION   NM_001024237 XM_213840
VERSION     NM_001024237.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1839)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 1839)
  AUTHORS   Finarov,I., Moor,N., Kessler,N., Klipcan,L. and Safro,M.G.
  TITLE     Structure of human cytosolic phenylalanyl-tRNA synthetase: evidence
            for kingdom-specific design of the active sites and tRNA binding
            patterns
  JOURNAL   Structure 18 (3), 343-353 (2010)
   PUBMED   20223217
REFERENCE   3  (bases 1 to 1839)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 1839)
  AUTHORS   Mirande,M., Le Corre,D., Louvard,D., Reggio,H., Pailliez,J.P. and
            Waller,J.P.
  TITLE     Association of an aminoacyl-tRNA synthetase complex and of
            phenylalanyl-tRNA synthetase with the cytoskeletal framework
            fraction from mammalian cells
  JOURNAL   Exp Cell Res 156 (1), 91-102 (1985)
   PUBMED   3880707
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000019.1.
            
            On May 26, 2021 this sequence version replaced NM_001024237.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC094515.1, SRR26360181.1946900.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760433 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-201               JAXUCZ010000019.1  40205623-40205823   c
            202-339             JAXUCZ010000019.1  40203940-40204077   c
            340-438             JAXUCZ010000019.1  40203757-40203855   c
            439-557             JAXUCZ010000019.1  40203550-40203668   c
            558-650             JAXUCZ010000019.1  40201348-40201440   c
            651-779             JAXUCZ010000019.1  40201138-40201266   c
            780-895             JAXUCZ010000019.1  40200945-40201060   c
            896-980             JAXUCZ010000019.1  40197984-40198068   c
            981-1080            JAXUCZ010000019.1  40197794-40197893   c
            1081-1249           JAXUCZ010000019.1  40197524-40197692   c
            1250-1327           JAXUCZ010000019.1  40197355-40197432   c
            1328-1442           JAXUCZ010000019.1  40197092-40197206   c
            1443-1839           JAXUCZ010000019.1  40196255-40196651   c
FEATURES             Location/Qualifiers
     source          1..1839
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q11"
     gene            1..1839
                     /gene="Farsa"
                     /gene_synonym="Farsla"
                     /note="phenylalanyl-tRNA synthetase subunit alpha"
                     /db_xref="GeneID:288917"
                     /db_xref="RGD:1310314"
     exon            1..201
                     /gene="Farsa"
                     /gene_synonym="Farsla"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..1581
                     /gene="Farsa"
                     /gene_synonym="Farsla"
                     /EC_number="6.1.1.20"
                     /note="phenylalanyl-tRNA synthetase alpha chain; pheRS;
                     phenylalanine--tRNA ligase alpha chain; phenylalanine-tRNA
                     synthetase-like, alpha subunit; phenylalanyl-tRNA
                     synthetase, alpha subunit"
                     /codon_start=1
                     /product="phenylalanine--tRNA ligase alpha subunit"
                     /protein_id="NP_001019408.1"
                     /db_xref="GeneID:288917"
                     /db_xref="RGD:1310314"
                     /translation="MADNPVLEQLLRRLEVADGGLDSAELATQLGVEHQAVVGAVKSL
                     QALGEVIEAELRSTKCWELTTEGEEIAREGSHEARVFRSIPLEGLVQSELMQLPSGKV
                     GFSKAMSNKWIRVDKSAADGPRVFRVVDSIEDEVQRRLQQVQAGQAEKLAEKERNELR
                     KRKLLTEVILKTYWVSKGKGFSTSVSKQEAELSPEMISSGSWRDRPFKPYNFSARGVL
                     PDSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDT
                     FFLRDPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYTWKLEEARKNLLRTHTTAASAR
                     ALYRLAQKKPFTPAKYFSIDRVFRNETLDATHLAEFHQIEGVIADHGLTLGHLMGVLR
                     EFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGLPE
                     NVSVIAWGLSLERPTMIKYGINNIRELVGHKVNLQMVYDSPVCRLDIEPRSSKTQEAA
                     "
     exon            202..339
                     /gene="Farsa"
                     /gene_synonym="Farsla"
                     /inference="alignment:Splign:2.1.0"
     exon            340..438
                     /gene="Farsa"
                     /gene_synonym="Farsla"
                     /inference="alignment:Splign:2.1.0"
     exon            439..557
                     /gene="Farsa"
                     /gene_synonym="Farsla"
                     /inference="alignment:Splign:2.1.0"
     exon            558..650
                     /gene="Farsa"
                     /gene_synonym="Farsla"
                     /inference="alignment:Splign:2.1.0"
     exon            651..779
                     /gene="Farsa"
                     /gene_synonym="Farsla"
                     /inference="alignment:Splign:2.1.0"
     exon            780..895
                     /gene="Farsa"
                     /gene_synonym="Farsla"
                     /inference="alignment:Splign:2.1.0"
     exon            896..980
                     /gene="Farsa"
                     /gene_synonym="Farsla"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1080
                     /gene="Farsa"
                     /gene_synonym="Farsla"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1249
                     /gene="Farsa"
                     /gene_synonym="Farsla"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1327
                     /gene="Farsa"
                     /gene_synonym="Farsla"
                     /inference="alignment:Splign:2.1.0"
     exon            1328..1442
                     /gene="Farsa"
                     /gene_synonym="Farsla"
                     /inference="alignment:Splign:2.1.0"
     exon            1443..1839
                     /gene="Farsa"
                     /gene_synonym="Farsla"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtttcccta gtccgtccgg cggcctacac acgttaaatg cgctagggat agccatggcg
       61 gataatcccg tcttggagca gttgctgcgg aggctggagg tagctgatgg cggcctggac
      121 agcgcggagt tggctacgca gctgggcgtg gagcaccagg cagtggtggg cgctgtgaag
      181 agcctccagg ctctgggtga agtcattgaa gccgagcttc gttctaccaa gtgctgggag
      241 ctgactactg agggtgagga gattgcccgg gagggcagcc atgaggcccg tgtgtttaga
      301 agcatccctc tcgagggcct ggtgcaaagt gagctcatgc aactgcccag cggcaaggtg
      361 ggcttcagca aggccatgtc caacaagtgg atccgagtgg acaagagtgc agccgatggg
      421 ccccgggtgt tccgcgtggt ggacagtata gaggatgaag tacagaggcg gctgcagcag
      481 gtccaggcag gccaggctga gaagctggct gaaaaggaaa ggaatgagct ccggaagagg
      541 aagctgctga ccgaagtgat cctgaaaacc tactgggtga gcaagggcaa gggcttcagc
      601 acaagtgtgt ctaagcagga ggccgagctg agcccagaga tgatctccag tggctcctgg
      661 agggaccgac ccttcaaacc ctacaacttc tctgcccgtg gtgtgctccc agacagtggc
      721 cacctgcacc ccttactcaa ggtccgctcc cagttccgac aaatcttctt ggagatgggg
      781 ttcacagaga tgcctacgga caatttcatc gagagctcct tctggaactt tgatgcactc
      841 ttccagcctc agcagcaccc agcgcgtgac caacatgata ctttcttcct gcgagatcca
      901 gccgaggccc tgcagctccc aatggactat gtccagcggg tgaaacggac ccactcccag
      961 ggtggctacg gctcacaagg ctacaagtat acctggaagc tggaagaggc ccggaaaaac
     1021 ctgcttcgca cacataccac agcagccagc gcccgagccc tctaccgttt agcccagaag
     1081 aagccattta caccagccaa gtacttctct attgatcgtg tgtttcggaa tgagacgctg
     1141 gacgccacac acctggccga gttccaccag attgagggtg tgatagctga ccatggtctc
     1201 accctgggcc acctcatggg tgtactgagg gagttcttca ccaagctggg aatcacacag
     1261 ctgcgcttca agccggccta caacccctac acagagccca gcatggaagt gttcagctac
     1321 caccaaggtc taaagaagtg ggttgaagtt ggcaactctg gagtcttccg ccctgagatg
     1381 ctcctgccta tggggctccc tgagaatgtg tctgtcattg cttggggtct ctctctggag
     1441 cgcccaacaa tgatcaaata tggtatcaat aacatccgag agctggtggg ccacaaggtg
     1501 aacctgcaga tggtatacga cagccccgtg tgccgactgg acattgagcc caggtcctca
     1561 aagacacagg aggctgcatg ataacaggct gccccagcga tccctgtcta gtccctgtgc
     1621 atcccgcagc agtgacctag tatttatgag gcctccgtga ggccagctgt cttcctctgc
     1681 ctcacacacc ccaagggtag ggttccaact atgggagcag gttccttgtg gtggctttta
     1741 gtggtctgtg tagtttgctt gtgaggatgg gtttgggccc tacaggttag ctgtttaata
     1801 aagtgggcac gttcccttgg gtggtgcctt ttgttagga
//
