LOCUS       NM_001107287            4564 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Rattus norvegicus FERM, ARH/RhoGEF and pleckstrin domain protein 1
            (Farp1), mRNA.
ACCESSION   NM_001107287 XM_001078859 XM_224535
VERSION     NM_001107287.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4564)
  AUTHORS   Cheadle,L. and Biederer,T.
  TITLE     Activity-dependent regulation of dendritic complexity by semaphorin
            3A through Farp1
  JOURNAL   J Neurosci 34 (23), 7999-8009 (2014)
   PUBMED   24899721
  REMARK    GeneRIF: This study support that Farp1 signaling is necessary for
            the high extent of arborization of maturing dendrites.
REFERENCE   2  (bases 1 to 4564)
  AUTHORS   Cheadle,L. and Biederer,T.
  TITLE     The novel synaptogenic protein Farp1 links postsynaptic
            cytoskeletal dynamics and transsynaptic organization
  JOURNAL   J Cell Biol 199 (6), 985-1001 (2012)
   PUBMED   23209303
REFERENCE   3  (bases 1 to 4564)
  AUTHORS   Hendrickx,A., Beullens,M., Ceulemans,H., Den Abt,T., Van Eynde,A.,
            Nicolaescu,E., Lesage,B. and Bollen,M.
  TITLE     Docking motif-guided mapping of the interactome of protein
            phosphatase-1
  JOURNAL   Chem Biol 16 (4), 365-371 (2009)
   PUBMED   19389623
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473951.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_224535.4, XM_001078859.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5756307,
                              SAMEA5760384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4564
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q24"
     gene            1..4564
                     /gene="Farp1"
                     /note="FERM, ARH/RhoGEF and pleckstrin domain protein 1"
                     /db_xref="GeneID:306183"
                     /db_xref="RGD:1305346"
     exon            1..193
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..3172
                     /gene="Farp1"
                     /note="FERM, RhoGEF and pleckstrin domain-containing
                     protein 1; FERM, RhoGEF (Arhgef) and pleckstrin domain
                     protein 1 (chondrocyte-derived); FERMRhoGEF (Arhgef) and
                     pleckstrin domain protein 1-like"
                     /codon_start=1
                     /product="FERM, ARHGEF and pleckstrin domain-containing
                     protein 1"
                     /protein_id="NP_001100757.1"
                     /db_xref="GeneID:306183"
                     /db_xref="RGD:1305346"
                     /translation="MGEIEQKPTPASRLGAPENSGISTLERGQKPPPTPSGKLMTVKI
                     QMLDDTQEAFEVPQRAPGKVLFDAVCNHLNLVEGDYFGLEFPDHRKIVVWLDLLKPIV
                     KQIRRPKHVLVKFVVKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLI
                     SHIVQSEIGDFDEALDREHLAKNKYVPQQDALEDKIVEFHHSHIGQTPAESDFQLLEV
                     ARRLEMYGIRLHPAKDREGTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRF
                     LIKLRPDVNSSYQDTLEFLMAGRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRG
                     SSFRFSGRTQKQVLDYVKEGGHKKVQFERKHSKIHSTRSLVSQPTAPNSEVPKQSPQS
                     ASLTFGEGTESPSAQSCQQAKETKVCTLEPGPRQSPALSKSPSGSKAADGTAAAAPPE
                     EEDEEEGGKDGIRPSNPQPPQPSTGSLTGSPHLSELSINSQGGAAPANVTLSPNLSPD
                     NKQASPLISPLLNDQACPRTDDEEEGRRKRFPTDKAYYIAKEVSTTERTYLKDLEVIA
                     SWFQSTVSKEDSMPEALKSLIFPNFEPLHKFHTNFLKEIEQRLALWEGRSNAHIRGDY
                     QRIGDVMLKNIQGMKHLAAHLWKHSEALEALETSIKGSRRLEHFCRDFELQKVCYLPL
                     NTFLLRPLHRLMHYKQVLERLCKHHPPNHADFRDCRAALAEITEMVAQLHGTMIKMEN
                     FQKLHELKKDLIGIDNLVIPGREFIRLGSLSKLSGKGLQQRMFFLFNDVLLYTSRGLT
                     ASNQFKVHGQLPLYGMTIEESEEEWGVPHCLTLRGQRQSIIVAASSRSEMEKWLEDIQ
                     MAIDLAEKSNGPTPELLASSPPDNKSPDEATAADQESEDDLSASRTSLERQAPHRGNT
                     MVHVCWHRSTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVFTNFCLFFYKSHQ
                     DSHPLASLPLLGYSLTIPSESENIHKDYVFKLHFKSHVYYFRAESEYTFERWMEVIRS
                     ATSSASRAHSLSHKESHLY"
     exon            194..298
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            299..341
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            342..420
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            421..518
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            519..633
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            634..781
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            782..877
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            878..1041
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1110
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..1186
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1187..1445
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1446..1633
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1634..1723
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1724..1857
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1858..1939
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1940..2177
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2178..2308
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2309..2377
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2378..2467
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2468..2550
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2551..2663
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2664..2830
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2831..2938
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2939..3090
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
     exon            3091..4564
                     /gene="Farp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcttatataa gctactttca tcatgggaga aatagagcag aagcccaccc cagcatcacg
       61 tctgggggcc ccagagaact cggggatcag caccttggaa cgaggacaga aaccaccgcc
      121 cacaccttca ggaaaactta tgactgtcaa aatccagatg ctggacgaca cccaggaagc
      181 ctttgaagtt ccacaacggg caccagggaa ggtcctcttt gatgctgtgt gcaaccacct
      241 caaccttgtg gagggtgact acttcggcct ggagttccct gaccacagaa agatcgtggt
      301 gtggctggat cttctgaagc ccattgtgaa gcagattcga aggccgaagc acgtgcttgt
      361 taagtttgtt gtgaaattct tcccgcccga ccacacccaa ctccaggaag aactcaccag
      421 gtacctgttc gccctgcagg tgaagcagga cttggctcaa ggcaggctga cgtgtaacga
      481 caccagcgcg gctctcttga tctcgcacat cgtacaatct gagattgggg atttcgacga
      541 agctttggac agagaacact tagcaaaaaa taagtatgta cctcaacagg atgcactaga
      601 agacaaaatc gtggagttcc accacagcca cattggacaa accccggcag agtcagattt
      661 ccagctcctg gaggtggccc gtcgactgga gatgtatgga atccggttac accctgccaa
      721 ggacagggaa ggcaccaaga tcaaccttgc tgtcgccaac actggaattc tagtgtttca
      781 gggcttcacg aagatcaatg cttttaactg ggccaaggtg cggaagctga gcttcaagcg
      841 gaagcgtttc ctcatcaagc tcagacctga cgtgaacagc tcgtaccagg acaccttgga
      901 gttcctgatg gccggtcgag acttctgcaa gtccttctgg aagatatgtg tggaacacca
      961 tgccttcttc agactctttg aagaacccaa gccaaagcca aagccagttc tcttcagccg
     1021 agggtcgtcc ttccggttta gtggtcggac tcagaagcaa gttcttgact acgttaaaga
     1081 aggaggccac aagaaagtgc agtttgaaag aaaacacagc aagatccatt ccactaggag
     1141 ccttgtctca cagcccacag caccgaattc ggaagtgcca aaacagtctc cgcagagcgc
     1201 cagccttacg ttcggtgaag gtaccgagtc tcccagtgcc cagagctgcc aacaagccaa
     1261 ggaaacgaaa gtttgtacct tggagcctgg accgcgccaa agtcccgccc tctctaagag
     1321 cccttcaggg agcaaagctg cggatggaac cgctgctgcg gcaccgcccg aggaagagga
     1381 tgaggaagag ggtggcaagg atggcatccg gccaagtaac cctcagcccc cgcagccaag
     1441 cacaggctcc ctgactggta gccctcacct ttcagagctg tccatcaact cgcagggagg
     1501 agccgcccca gccaacgtga ccctgtctcc caacctgagt cctgacaaca agcaggcctc
     1561 tcccctgatc agcccgctcc tgaacgacca agcgtgccca aggaccgacg atgaagaaga
     1621 gggccggcga aagagattcc caaccgacaa ggcatactac attgctaagg aagtctccac
     1681 cacagaacgc acatacctga aggatcttga ggtcatcgct tcgtggttcc agagcacagt
     1741 cagcaaagag gactccatgc ctgaagcttt gaaaagtctc atatttccaa acttcgaacc
     1801 tttgcacaag ttccacacca attttctgaa ggagattgag cagcgtctcg ccctgtggga
     1861 aggccgctca aacgcccaca tcagaggaga ttaccaaaga atcggggacg tcatgctgaa
     1921 gaacattcag ggcatgaagc acctggcggc ccacctctgg aagcacagcg aggccttgga
     1981 ggccctggag acctccatca agggctcccg gcggctggaa cacttctgcc gagacttcga
     2041 gttgcagaag gtgtgttacc tgccgctcaa caccttcctc ctgcgcccgc tgcaccggct
     2101 catgcactac aagcaggtcc tggagaggct gtgcaagcat caccctccga accatgccga
     2161 cttcagggac tgcagagctg cgctggcaga gatcacagag atggtggcac agctgcacgg
     2221 taccatgatc aagatggaga acttccagaa gctgcatgag ctcaagaagg atctgattgg
     2281 cattgacaat cttgtgatcc caggaaggga gttcatccgc ctgggtagcc tcagcaagct
     2341 ctccgggaag gggcttcaac agcgcatgtt cttcctgttc aacgatgtct tgctgtatac
     2401 cagccgggga ctgacggcat ctaatcagtt taaagtccac ggacagctcc cgctctatgg
     2461 catgacgatc gaggagagtg aggaggagtg gggcgtaccc cactgcctga ccctgcgggg
     2521 ccagcggcag tccatcatcg tggccgccag ttcccgatca gagatggaaa aatggctgga
     2581 ggacatccag atggccattg acctggctga gaaaagcaat gggcccaccc ccgaactcct
     2641 cgccagcagc ccccctgaca acaagtcccc ggatgaagcc acagctgctg accaggagtc
     2701 agaagacgac ctgagcgcct ctcggacctc gctggagcgc caggcccctc accgtggcaa
     2761 caccatggtg cacgtgtgct ggcatcgcag caccagcgtc tccatggtgg acttcagcat
     2821 tgccgtggag aaccagctct ctgggaactt gctgagaaag ttcaagaaca gcaatggctg
     2881 gcagaagctg tgggtggtat tcaccaactt ctgcctgttc ttctacaaat cacaccagga
     2941 cagtcacccc ctcgccagtc taccgctgtt gggctactca ctcaccattc cctcagagtc
     3001 tgagaacatc cacaaggact acgtgttcaa gctgcacttc aagtcccacg tgtactactt
     3061 cagggctgaa agcgaataca catttgaaag gtggatggaa gtgatccgaa gtgccaccag
     3121 ctcggcctct cgggcccaca gcctgagtca caaagaatct cacctgtact gacggctgga
     3181 cacgcccact ggacacgccc actgccgcac catccatggc tgctttcctg gaggatacct
     3241 tgaaatccag caaaatccat acctgtgtga gcacaccgat ggtctgcagt ggttctcgcc
     3301 cacctccctt tacaggccaa tatccaaaca ttgtcttttc cagtactagt ctctttggac
     3361 agcctttccc tccaggccta gggcatggga gggcttgtct tgccattcct tctccagggg
     3421 cactttagct tgtgccagca ttgacacagt gtcatcaaga gtgccaaacg actgcagtac
     3481 atccagcgca gggccccatg ccccttcacc gtgtcagaga agacatggcg agtgggcttt
     3541 tcacctacag actgcggctt tccaaacgga tttccccagt gtttgcaaca cacagcgcag
     3601 tcttaagtaa atgagatcat ttttggattt catttttttc cagtctttct acttttataa
     3661 taggacatcc gtaggactca cttttctgga ataagcaatt tgtggagtac tccattccac
     3721 taaaggggtt ggctccaggg agaccctggt tgccataccc acttccttgg tggaagttga
     3781 ccaaactgtt tgtgattact atttacaaaa atgtagtggg gttgttttct gtggagaagc
     3841 agatacccag tggaatacgt gggcgtcacc gccctgcgtg tggcgtgttc agtggggact
     3901 cctaggccgt gatgttttgc tgtctgtttc acaagcatga gaaggtgtat gtcgttgact
     3961 ggggccattt gtgctgttac attttggggc attgagtgag cttcttggag aagcactgta
     4021 tggaaatggt acgtaatccc aaccctggtg attggcccca actccccgca aggccgtggt
     4081 ttggtttgaa cccgcacatt ctctaatagt atctattgtg cctgtcttca agtctttctc
     4141 tttttatact cattccttct gggcacgggg tacagacagg atgacagccc acatcctgga
     4201 cagactcctc tgggggacct ggttgccaaa cactacctga gcctcccagt ggaaaaatgt
     4261 ttgcttgttc tctagggtgg ctgggtggct gccattccct tcatgcacag agcctgctat
     4321 aatgcaagct ggccaggtca gcagtcccct ctccctgtgc cctacacccc agcaagggcc
     4381 ttcttacctg aaaacagacc caacgttgag ggtttgcggc tggtgtcaga gactcacatg
     4441 gatgaggagt aagatgtgtc aatcatttgc cttacaatgt accagatggt tctaagtact
     4501 aacaaaaggg aataaaaata cctcaagcca cgatccagca cacacagtct gaggcaaaac
     4561 cacc
//
