LOCUS       NM_001191718            1864 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus FA complementation group E (Fance), mRNA.
ACCESSION   NM_001191718 XM_228032
VERSION     NM_001191718.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1864)
  AUTHORS   Fu,C., Begum,K. and Overbeek,P.A.
  TITLE     Primary Ovarian Insufficiency Induced by Fanconi Anemia E Mutation
            in a Mouse Model
  JOURNAL   PLoS One 11 (3), e0144285 (2016)
   PUBMED   26939056
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1864)
  AUTHORS   Kim,H., Yang,K., Dejsuphong,D. and D'Andrea,A.D.
  TITLE     Regulation of Rev1 by the Fanconi anemia core complex
  JOURNAL   Nat Struct Mol Biol 19 (2), 164-170 (2012)
   PUBMED   22266823
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1864)
  AUTHORS   Yan,Z., Delannoy,M., Ling,C., Daee,D., Osman,F., Muniandy,P.A.,
            Shen,X., Oostra,A.B., Du,H., Steltenpool,J., Lin,T., Schuster,B.,
            Decaillet,C., Stasiak,A., Stasiak,A.Z., Stone,S., Hoatlin,M.E.,
            Schindler,D., Woodcock,C.L., Joenje,H., Sen,R., de Winter,J.P.,
            Li,L., Seidman,M.M., Whitby,M.C., Myung,K., Constantinou,A. and
            Wang,W.
  TITLE     A histone-fold complex and FANCM form a conserved DNA-remodeling
            complex to maintain genome stability
  JOURNAL   Mol Cell 37 (6), 865-878 (2010)
   PUBMED   20347428
REFERENCE   4  (bases 1 to 1864)
  AUTHORS   de Winter,J.P., Leveille,F., van Berkel,C.G., Rooimans,M.A., van
            Der Weel,L., Steltenpool,J., Demuth,I., Morgan,N.V., Alon,N.,
            Bosnoyan-Collins,L., Lightfoot,J., Leegwater,P.A., Waisfisz,Q.,
            Komatsu,K., Arwert,F., Pronk,J.C., Mathew,C.G., Digweed,M.,
            Buchwald,M. and Joenje,H.
  TITLE     Isolation of a cDNA representing the Fanconi anemia complementation
            group E gene
  JOURNAL   Am J Hum Genet 67 (5), 1306-1308 (2000)
   PUBMED   11001585
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Jul 17, 2010 this sequence version replaced XM_228032.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                JAXUCZ010000020.1  6371153-6371162
            11-299              JAXUCZ010000020.1  6377310-6377598
            300-900             JAXUCZ010000020.1  6378660-6379260
            901-945             JAXUCZ010000020.1  6379849-6379893
            946-1011            JAXUCZ010000020.1  6380140-6380205
            1012-1155           JAXUCZ010000020.1  6380435-6380578
            1156-1279           JAXUCZ010000020.1  6380952-6381075
            1280-1358           JAXUCZ010000020.1  6381254-6381332
            1359-1425           JAXUCZ010000020.1  6383096-6383162
            1426-1551           JAXUCZ010000020.1  6385358-6385483
            1552-1864           JAXUCZ010000020.1  6388054-6388366
FEATURES             Location/Qualifiers
     source          1..1864
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1864
                     /gene="Fance"
                     /gene_synonym="RGD1561045"
                     /note="FA complementation group E"
                     /db_xref="GeneID:309643"
                     /db_xref="RGD:1561045"
     CDS             1..1653
                     /gene="Fance"
                     /gene_synonym="RGD1561045"
                     /note="Fanconi anemia, complementation group E"
                     /codon_start=1
                     /product="Fanconi anemia group E protein"
                     /protein_id="NP_001178647.1"
                     /db_xref="GeneID:309643"
                     /db_xref="RGD:1561045"
                     /translation="MAPGALRPRVSCPPPRLGSPLARPVSDAVASARATPWATLEAPA
                     RLLLQALQAGPEGARRGLGVLRTLGRRAEHFPWDSFLEALGRAEPEVRGPDGRLELTP
                     LLLRLPGVCRKNLMSLLLAVRSSLPESGLRSVLQLDQQGTASTSDAWLHALRELLQRD
                     VGLGVSVEGSSPLTGSCQSHLRDLCGRLGQGGRGLKPALGSDPEPEGRLSQLSGKRRK
                     RTEGETAGPELERSPKRFRGCEEEQEEVVERKEERPKPETSESESDAGGVLPDTEVEA
                     PEARPGVAEAESPAKSVELPKVVQDQVPRLRQLLKALQEGLEGLEEPPVDLQFLHECS
                     PSQMESLCSQLQLPQLPDGGLLQLCSHLLGLTPALSISNASVLARSLFLDRILSLPSS
                     ASRLLRAALTSFCAKYTYAVCRAVLCPLFQDPGIGPVQTELLCSLLKDESLEPDMQVQ
                     ILGQVLELAWREETFLVLQALLERQVEMTSELFSVLMQRLCKEGPAATTSMAYAKLML
                     TVMTKYQASISQQQSLDLAVALEPNTTFLKKSLQAALRHLAR"
     exon            1..10
                     /gene="Fance"
                     /gene_synonym="RGD1561045"
                     /inference="alignment:Splign:2.1.0"
     exon            11..299
                     /gene="Fance"
                     /gene_synonym="RGD1561045"
                     /inference="alignment:Splign:2.1.0"
     exon            300..900
                     /gene="Fance"
                     /gene_synonym="RGD1561045"
                     /inference="alignment:Splign:2.1.0"
     exon            901..945
                     /gene="Fance"
                     /gene_synonym="RGD1561045"
                     /inference="alignment:Splign:2.1.0"
     exon            946..1011
                     /gene="Fance"
                     /gene_synonym="RGD1561045"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1155
                     /gene="Fance"
                     /gene_synonym="RGD1561045"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1279
                     /gene="Fance"
                     /gene_synonym="RGD1561045"
                     /inference="alignment:Splign:2.1.0"
     exon            1280..1358
                     /gene="Fance"
                     /gene_synonym="RGD1561045"
                     /inference="alignment:Splign:2.1.0"
     exon            1359..1425
                     /gene="Fance"
                     /gene_synonym="RGD1561045"
                     /inference="alignment:Splign:2.1.0"
     exon            1426..1551
                     /gene="Fance"
                     /gene_synonym="RGD1561045"
                     /inference="alignment:Splign:2.1.0"
     exon            1552..1864
                     /gene="Fance"
                     /gene_synonym="RGD1561045"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcacctg gggcgctccg accccgagtg tcctgtccgc cgccccgcct cggctctccg
       61 ctggcgaggc cagtgtcgga cgccgtggcc tcggccaggg cgacgccatg ggcgaccctg
      121 gaggcccccg cccgtctcct cctgcaggcg ctgcaggccg gacccgaggg tgcgcggcgc
      181 gggctagggg ttctgcgcac cttgggccgc cgcgctgagc acttcccttg ggatagcttc
      241 ctggaggcgc tgggccgcgc agagcccgaa gtgcggggcc cagatggccg cctggaactg
      301 acgccactgt tgctacggtt gcctggagta tgccggaaga acctgatgtc cttgctgctg
      361 gctgttcgat cctccttacc cgaaagcggc ctccgctctg tgctgcagct tgatcagcag
      421 ggcacagcat ctacctctga tgcctggctc cacgccctca gggagctgct gcaaagggat
      481 gtggggcttg gagtctctgt ggagggatcc tccccattga ccggaagctg tcagtcacat
      541 ctccgggacc tgtgtgggcg gctgggccaa ggtgggaggg ggctgaaacc ggccctgggt
      601 tctgatcctg aaccagaggg cagactctca cagctttctg ggaagcggag gaaaaggacc
      661 gagggagaga ctgccggccc tgagttagag agatccccta aaaggttccg gggttgtgag
      721 gaggaacagg aagaggtggt ggaaagaaag gaagagagac ccaagccaga gacttcggaa
      781 tcagagtcag atgcaggagg cgtgttgcct gatactgaag tcgaggctcc ggaggctcgc
      841 ccgggcgtag cagaggccga gagtccagct aagagtgtgg agctccccaa agttgtccag
      901 gaccaggtgc ccaggctgcg gcagctgctg aaggccttgc aggaggggct ggaggggctg
      961 gaggagcccc cagtggacct gcagtttctt cacgaatgta gtcccagcca gatggagtcg
     1021 ctatgcagcc agctacaact gccccagctc ccggacggag gcctcctgca gctctgcagc
     1081 cacctgctgg gtctcacccc agccctcagc atcagcaatg cctctgtgct ggccaggagc
     1141 ctctttcttg accggatcct ctccctgcca tcctccgcct ccaggcttct cagagctgcc
     1201 ctcacctcct tctgtgccaa gtacacctac gctgtctgca gggctgtcct ctgtcccttg
     1261 ttccaggacc caggcatagg tcctgtgcag acggagttac tgtgttccct cttaaaggat
     1321 gagtccttgg agccagacat gcaggtccag attctggggc aggtcctgga gctggcctgg
     1381 agggaagaga cgttcctggt gttgcaggcg ctcctggagc ggcaggtgga gatgacctcg
     1441 gagctcttca gtgtcttgat gcagaggctc tgcaaagagg ggccggcagc caccacctcc
     1501 atggcctatg ccaagctgat gctgacggtg atgaccaagt accaggccag catctcacag
     1561 cagcagagtc tggacctggc tgtggcccta gagcccaaca ccaccttcct gaagaagtcc
     1621 ctgcaggcag ccctgagaca tctggcccgc tgaccaccca caccccaggc tgtgcagggg
     1681 ccatcttgtc tccacagaga gcagagagga ggccctggct gctcctccac tcctgacaac
     1741 atctcgatcc agggccggtg gaggatgagc gggaatcttt cgcgctcatg tgtgtgttgt
     1801 gacccccttc tgaactgagt aattctgtaa tggttcttaa taaagagaag acagttcatc
     1861 caca
//
