LOCUS       NM_001015013            1215 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Rattus norvegicus family with sequence similarity 89, member B
            (Fam89b), mRNA.
ACCESSION   NM_001015013 XM_219519
VERSION     NM_001015013.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Lee,I.C.J., Leung,T. and Tan,I.
  TITLE     Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related
            Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in
            lamellipodial F-actin dynamics
  JOURNAL   J Biol Chem 289 (39), 26989-27003 (2014)
   PUBMED   25107909
  REMARK    GeneRIF: the functional relevance of the LRAP25-MRCK complex in
            LIMK1-cofilin signaling and the importance of LRAP adaptors as key
            determinants of MRCK cellular localization and downstream
            specificities.
REFERENCE   2  (bases 1 to 1215)
  AUTHORS   Kokura,K., Kim,H., Shinagawa,T., Khan,M.M., Nomura,T. and Ishii,S.
  TITLE     The Ski-binding protein C184M negatively regulates tumor growth
            factor-beta signaling by sequestering the Smad proteins in the
            cytoplasm
  JOURNAL   J Biol Chem 278 (22), 20133-20139 (2003)
   PUBMED   12646588
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC093377.1.
            
            On Apr 20, 2005 this sequence version replaced XM_219519.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC093377.1, EV779280.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1215
                     /gene="Fam89b"
                     /gene_synonym="Mtvr2"
                     /note="family with sequence similarity 89, member B"
                     /db_xref="GeneID:309170"
                     /db_xref="RGD:1311544"
     exon            1..408
                     /gene="Fam89b"
                     /gene_synonym="Mtvr2"
                     /inference="alignment:Splign:2.1.0"
     CDS             118..687
                     /gene="Fam89b"
                     /gene_synonym="Mtvr2"
                     /note="protein FAM89B; mammary tumor virus receptor 2"
                     /codon_start=1
                     /product="leucine repeat adapter protein 25"
                     /protein_id="NP_001015013.1"
                     /db_xref="GeneID:309170"
                     /db_xref="RGD:1311544"
                     /translation="MNGLPSTEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERV
                     YSQRSRIHDELSRAARAPDGPRHAAGSANLGSAAGPRRPVNLDSALAALRKEMVGLRQ
                     LDMSLLCQLWGLYESIQDYKHLCQDLSLCQDLSSSLHSDSSYPPDAGLSDDDEPPDAS
                     LPPDPPPLTVPQTHNARDQWLQDAFQISL"
     exon            409..1191
                     /gene="Fam89b"
                     /gene_synonym="Mtvr2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgggcggcgg ctgggctctc tccggaggcc gggccacaga gagcgggtcc tctgggcagc
       61 agtccgcagc aaacgtagga ggggtggagg cggcatcgcg gtccgcgcgg tctggctatg
      121 aacgggctgc cctcaactga ggcgcccggt ggcgcgggct gcgctctggc tgggctcccg
      181 ccgctaccgc gcggcctcag cggccttctt aacgctagtg gtggctcgtg gagggagcta
      241 gagcgtgtct acagccaacg gagccgcatc cacgacgagc tgagtcgtgc cgcccgcgcc
      301 ccggatggtc ctcgccacgc cgcgggctct gccaatttag gctctgcagc gggcccgcgc
      361 cgcccggtta acctcgactc tgcactggcc gcgctgcgca aggaaatggt gggtctgcga
      421 cagctggata tgtccctgct gtgccagctg tggggcctgt atgagtcgat ccaggactac
      481 aagcatctgt gccaagacct gagcttgtgc caggacctgt catcctctct gcactccgac
      541 agctcctacc cacccgatgc cggcctgtct gatgacgatg agcctcctga tgccagcctg
      601 cccccagacc ctccacccct caccgtgccc cagactcaca atgcccgtga ccagtggttg
      661 caggatgcct tccaaatcag cctttgaaaa gctgaggtgg attggaatgc acccacacaa
      721 aaggctcaaa acttgccctt cagcaagtcc ttagtcgaca gtgcctgctc ttttaccggt
      781 accacctcac ctcacttcag gagggcaagg cattataccc atcaggcaaa gcggtcaaga
      841 ttgcagcctc tacccggtgt actgggctaa cacttctccc acatgtgtgc accctagctt
      901 ggccagccct tagtctgacc gtggggccca aagcgtcttg cactcccgtt tgcatctctg
      961 ggactgggat gagtgcctag cttccatctc tttgtcgtct tttgctgcct cttgcagcta
     1021 ctggctcagg ggcatcacta cctgtggccc caggatttca ctgcctggga caagggctcc
     1081 agaacccacc tctgtagcca cccacgacca gaaaggctaa ggtctttatg ctggatattt
     1141 aagtttagcg gtcagttcct ggacagggaa ataaacaatt tcagcattgt aaaaaaaaaa
     1201 aaaaaaaaaa aaaaa
//
