LOCUS       NM_001130565            4523 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus family with sequence similarity 83, member H
            (Fam83h), mRNA.
ACCESSION   NM_001130565 XM_001070414 XM_343265
VERSION     NM_001130565.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4523)
  AUTHORS   Xie Y, Meng M, Cao L, Yang J, Ma Q, Huang X, Yu Y, Yang Q, Zou J
            and Du Q.
  TITLE     Amelogenesis imperfecta in a Chinese family resulting from a FAM83H
            variation and the effect of FAM83H on the secretion of enamel
            matrix proteins
  JOURNAL   Clin Oral Investig 27 (3), 1289-1299 (2023)
   PUBMED   36318336
  REMARK    GeneRIF: Amelogenesis imperfecta in a Chinese family resulting from
            a FAM83H variation and the effect of FAM83H on the secretion of
            enamel matrix proteins.
REFERENCE   2  (bases 1 to 4523)
  AUTHORS   Kuga T, Kume H, Kawasaki N, Sato M, Adachi J, Shiromizu T, Hoshino
            I, Nishimori T, Matsubara H and Tomonaga T.
  TITLE     A novel mechanism of keratin cytoskeleton organization through
            casein kinase Ialpha and FAM83H in colorectal cancer
  JOURNAL   J Cell Sci 126 (Pt 20), 4721-4731 (2013)
   PUBMED   23902688
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473950.2.
            
            On or before Jul 28, 2008 this sequence version replaced
            XM_001070414.1, XM_343265.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4523
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..4523
                     /gene="Fam83h"
                     /gene_synonym="RGD1305866"
                     /note="family with sequence similarity 83, member H"
                     /db_xref="GeneID:362937"
                     /db_xref="RGD:1305866"
     exon            1..134
                     /gene="Fam83h"
                     /gene_synonym="RGD1305866"
                     /inference="alignment:Splign:2.1.0"
     exon            135..596
                     /gene="Fam83h"
                     /gene_synonym="RGD1305866"
                     /inference="alignment:Splign:2.1.0"
     CDS             150..3779
                     /gene="Fam83h"
                     /gene_synonym="RGD1305866"
                     /codon_start=1
                     /product="protein FAM83H"
                     /protein_id="NP_001124037.1"
                     /db_xref="GeneID:362937"
                     /db_xref="RGD:1305866"
                     /translation="MARRSQSSSQGDNPLAPGYLPPHYKEYYRLAVDALTEGGQEAYN
                     RFLASEGAPDFLCPEELEHVSRHLQPPQYVSREPPEGAPPDVDMDGSSGTYWPVDSDQ
                     AVPELDLGWPLTFGFQGTEVTTLVQPPPPDSPSIKDEARRMIRSAQQVVAVVMDMFTD
                     VDLLSEVLEAAARRVPVYILLDEMNAQHFLDMADKCRVNLHHVDFLRVRTVAGPTYYC
                     RTGKSFKGHLKEKFLLVDCAVVMSGSYSFMWSFEKIHRSLAHVFQGELVSSFDEEFRI
                     LFAQSEPLVPSAGALARMDAYALTPYSGAGPLVGVPGVGAPTPFSFPKRAHLLFPPPR
                     EEGLGFPSFLDPDRHFLSAFRRDELQRMPGGALEPHTGLRPLARPGEAGPLGELPGPR
                     GFFQSRHLEMDAFKRHSYTAADGAGAVENFAAARQVSRQTFLSHGDDFRFQTSHFQRD
                     QLYQQHYQWDPQFAPARPQGLFEKLRAGRPGFADPDDFALGAGHRFPELGADVHQRLE
                     YVPSSASREVRHGSDPAFGPSPRGLEPSGASRPNLGQRFPCQATLRQGLDTATEAEPE
                     RRGGPEGRAGLRHWRLASYLSGCHGDGGEEGLPMEAEACEDEVLAPGGRDLLPSTFRT
                     PAPFPAKGPKPGSGSGGGDSSEREGPEETGLIKQDSFRSRLNPLIQRSSRLRSSLIFA
                     SQAEGTAGTTAATTEKVQLMHKEQTISETLGPSGEAVRSSASAKVAELLEKYKGPARD
                     PGGAGGAITASSHSKAVVSQAWREEVVAPGGAGAERRSLESCLLDLRDSFAQQLHQEA
                     ERHPGAASLTAAQLLDTLGGTDRLPSRFLSAQGRSLSPQGRDSPPPEGLGTHQLPYSE
                     PKGSPTPAYPERKGSPTPAYPERKGSPTPAYPERKGSPTPAYPERKGSPTPAYPERKG
                     SPTSGFPNRRGSPTTGLMEQKGSPTSTYPDRRSSPVPPVPERRGSPVPPVPERRGSLT
                     FAGESSKTGPTEEVSGGPMEVLRKGSLRLRQLLSPKSERRGEDEVSFPAPQENGQPES
                     PRRPSLSRGDSTEAAAEERGSRVRLASATANALYSSNLRDDTKAILEQISAHGQKHRA
                     VPAPGPAHNSSDVGRPTTAGDLAPDMSDKDKCSAIFRSDSLGTQGRLSRTLPASAEER
                     DRLLRRMESMRKEKRVYSRFEVFCKKEDAGSSAAGDNLADEDTRDSKMGKFVPKILGT
                     FKSKK"
     exon            597..761
                     /gene="Fam83h"
                     /gene_synonym="RGD1305866"
                     /inference="alignment:Splign:2.1.0"
     exon            762..886
                     /gene="Fam83h"
                     /gene_synonym="RGD1305866"
                     /inference="alignment:Splign:2.1.0"
     exon            887..4523
                     /gene="Fam83h"
                     /gene_synonym="RGD1305866"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgggagcgtg aatcaggccg aacgggcggg cgggccgcgg cggggagtgg ctgtcggacg
       61 gaccggaccg cgaggccgct gggcggcggt gggctcctgc tgcccctgtg ccgaaacccc
      121 gctcacctgg ccaggccccc ggccccaaca tggcccgtcg ctcccagagc agctctcagg
      181 gggacaaccc attggcacct gggtacctgc cacctcacta caaagaatat tatcgcctag
      241 cagtggacgc actgactgag ggtgggcaag aagcctacaa ccgcttcttg gcatctgaag
      301 gggcacctga cttcctgtgc cctgaggaac tggaacatgt gagccgtcac ctgcagcccc
      361 cacagtatgt gtcccgggaa ccccctgaag gcgctcctcc tgatgtggac atggacggtt
      421 cctcaggcac ctactggcca gtggactcag accaggctgt gcctgagctg gacctgggct
      481 ggcccctgac atttggcttc caaggcacag aggtcaccac actggtacag ccgccgccac
      541 ctgacagccc cagcatcaaa gatgaagctc ggaggatgat ccgctctgcc cagcaggtgg
      601 tggctgtggt gatggacatg ttcactgacg tggatctgct cagtgaagtg ctagaggctg
      661 ctgcaaggcg agtcccggtc tacattctgc tggatgaaat gaacgcccag catttcctag
      721 acatggccga caagtgtcgc gtcaacctgc accacgtgga tttcctgcgc gtgcgcacag
      781 tggcaggccc tacttactac tgccgcactg ggaagtcttt caagggccat ctgaaggaga
      841 agttcttgct tgtggactgt gctgtagtga tgagcggtag ttatagcttc atgtggtcct
      901 tcgagaaaat tcaccgcagc ctggctcatg tgttccaggg agagctggtc tccagcttcg
      961 atgaagagtt ccgcattctc ttcgcacagt cggagcctct ggtgccctca gctggggcgc
     1021 tagcccgcat ggatgcctat gcgcttactc catactccgg ggctgggccc ctggtgggtg
     1081 tccccggggt tggagcacca acaccttttt ctttccctaa acgggcgcac ctcctgttcc
     1141 caccgcccag ggaagaaggc ctgggcttcc cctctttcct agaccctgac cgccacttcc
     1201 tatcggcatt ccgccgagac gagttgcagc ggatgcctgg gggtgctttg gagcctcaca
     1261 cagggctcag gccactggcg cgtccaggtg aggctgggcc actcggagag ctcccgggcc
     1321 cccggggctt cttccaatca cggcacctgg aaatggatgc cttcaagcgg cacagctata
     1381 cagcagcaga tggagctggg gcagtggaga actttgcagc tgcacggcag gtgtctcgac
     1441 aaacattcct cagtcatggt gatgacttcc gtttccagac cagccacttc caacgggacc
     1501 agctctacca gcagcattac caatgggacc cacaatttgc tcccgcgcgc ccacagggcc
     1561 tctttgagaa gcttcgagca ggccgacctg gctttgcgga ccctgacgac tttgcactag
     1621 gtgctgggca ccgcttccca gaactcggtg ctgatgtaca ccaacgactg gaatatgtgc
     1681 catccagcgc atctcgggag gtgcgccacg gctcggatcc cgcctttgga cccagccccc
     1741 gtggtctgga gcccagtggg gcctcgcgtc ccaatctggg ccagcgtttt ccatgccaag
     1801 caactttgag gcaaggcctg gacaccgcta cggaggcaga gcctgagcgc aggggtggac
     1861 ccgagggccg agctgggctg cgtcactggc gcctggcttc ctacctgagc ggctgccacg
     1921 gtgatggtgg agaggagggt ctacccatgg aggctgaggc ctgtgaagat gaggtgctgg
     1981 ctcctggagg ccgggaccta cttccctcca ccttccgcac tcctgcaccc ttcccagcta
     2041 agggaccaaa gccgggctca ggaagcggtg gtggtgacag ctccgagcga gagggcccag
     2101 aagagacagg cctgattaag caggactcct tccgctcacg cttaaacccg ctcatccagc
     2161 gcagctccag gctgcgctca tcactcatct ttgcgtcaca ggctgagggt actgctggga
     2221 ccacagcagc caccactgaa aaagtacagc tgatgcacaa agagcaaaca atcagtgaaa
     2281 ctctgggccc cagcggagag gctgttcgtt ccagcgcctc agccaaagtg gcggagctac
     2341 tggagaaata caagggccct gcccgagacc ctggcggtgc agggggtgcc atcactgcct
     2401 ccagccacag caaggctgta gtgtcccagg cctggcggga ggaggtggta gcaccaggag
     2461 gagcaggagc tgagcgccgt agccttgaga gttgcttgct agacctgcgc gactcctttg
     2521 cccagcagtt gcaccaagag gcagagcgac acccaggagc cgcttcccta actgctgcgc
     2581 aacttctcga cacgctgggc ggcacagacc gcctgccatc acgcttcctc tctgcccagg
     2641 gccgctcctt gtctccacaa ggtcgagata gccctccgcc agaagggctt gggacacacc
     2701 agctgcctta ttctgagcca aaagggagcc ccactccagc gtatcctgag cgcaagggga
     2761 gccccacacc agcttaccct gagcgcaagg ggagccccac tccagcctac cctgagcgta
     2821 aggggagccc tactccagcc taccctgagc gtaaggggag ccctactcca gcctaccctg
     2881 agcgcaaggg gagccccacg tctggatttc ccaatcggag gggcagccca accacaggat
     2941 tgatggagca gaaggggagt cccacctcga cctacccaga ccgtagaagc agcccggtgc
     3001 ccccagtgcc agagcgcagg ggtagcccag taccccccgt gcccgagcgc agaggcagtc
     3061 tcaccttcgc tggggagtct tcgaagactg ggcctacaga ggaggtgtct ggcggcccca
     3121 tggaagtcct gcgaaagggt tctctccgcc tcaggcagct actgagcccc aaaagtgagc
     3181 ggcgtggaga ggatgaggtc agtttcccag ctccgcagga gaatgggcag cctgagagtc
     3241 cccggcggcc ctcactgagt cgaggtgaca gcacagaggc tgctgcagag gagagaggct
     3301 caagggttcg cctagcttca gctactgcca atgctctgta cagcagcaac ctgagagatg
     3361 acacgaaggc cattctggag caaatcagtg cccatggcca gaagcaccgc gcagtccctg
     3421 ctccaggtcc agcccataac agttctgatg taggtcgccc aacaactgca ggagacttgg
     3481 caccagacat gtctgacaag gacaagtgtt cagccatctt ccgctcagac agcctaggga
     3541 cacaaggccg gctcagtcgc accctgccag ccagtgcaga ggagcgtgac cggctccttc
     3601 gccgcatgga gagcatgcgc aaagagaagc gtgtctacag tcgcttcgaa gtcttctgca
     3661 agaaggaaga cgctggcagt agtgcggcag gagacaactt ggcagatgag gacaccaggg
     3721 acagtaaaat gggcaaattt gttcccaaga tcctgggcac attcaaaagc aaaaagtgat
     3781 ctcctggtct tggaggccag gactctgcat cactgccata ccgtacccac aatgcccatc
     3841 tggagaggtg gctgccaggt cggtgtcaaa gcagtttggg acctggctga caaccacctc
     3901 aactgagctc cacttgaatt cgcctggcta cagcactgcc tcttgttctt ggcttttcca
     3961 cgaggggctc agcccctcca cctggtgcat tttcctgatc ccctccccca cctcagcctc
     4021 caccatctcc tgggctcagg tctactttgg gtcttatttc acctcaggga tctgtctgtc
     4081 tgccttattg tccagttctt caggaactct atcgctttgt gcctcaattc cttcttaagg
     4141 ccttttatct cagggctttt ttctcagggt ttgcagctca cagttcttgg ttccactgcc
     4201 tctggtgaca gcctcctccc accctctcat ctccatctct ctctggaaca caccttgcct
     4261 gttcccgctc tgtctcctcg ctgcctccta gcactttctc agcatctgcc ctcttgctat
     4321 gcggatggca gaattggcct caggcagttt aagggaagag agggacgctg gacaggacag
     4381 accattggaa aatagttgcc aaacacctag agaggcgcct caagacacat ctgccctctc
     4441 cagcaagttt ctgggtagta cctgaagagg agccaagact ggggagcatt ggactttgca
     4501 gtacaataaa ggaatctgaa cag
//
