LOCUS       NM_001107796            2253 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus family with sequence similarity 83, member D
            (Fam83d), mRNA.
ACCESSION   NM_001107796 XM_001068199 XM_230807
VERSION     NM_001107796.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2253)
  AUTHORS   Wang,D., Han,S., Peng,R., Wang,X., Yang,X.X., Yang,R.J., Jiao,C.Y.,
            Ding,D., Ji,G.W. and Li,X.C.
  TITLE     FAM83D activates the MEK/ERK signaling pathway and promotes cell
            proliferation in hepatocellular carcinoma
  JOURNAL   Biochem Biophys Res Commun 458 (2), 313-320 (2015)
   PUBMED   25646692
REFERENCE   2  (bases 1 to 2253)
  AUTHORS   Cipriano,R., Miskimen,K.L., Bryson,B.L., Foy,C.R., Bartel,C.A. and
            Jackson,M.W.
  TITLE     Conserved oncogenic behavior of the FAM83 family regulates MAPK
            signaling in human cancer
  JOURNAL   Mol Cancer Res 12 (8), 1156-1165 (2014)
   PUBMED   24736947
REFERENCE   3  (bases 1 to 2253)
  AUTHORS   Wang,Z., Liu,Y., Zhang,P., Zhang,W., Wang,W., Curr,K., Wei,G. and
            Mao,J.H.
  TITLE     FAM83D promotes cell proliferation and motility by downregulating
            tumor suppressor gene FBXW7
  JOURNAL   Oncotarget 4 (12), 2476-2486 (2013)
   PUBMED   24344117
REFERENCE   4  (bases 1 to 2253)
  AUTHORS   Santamaria,A., Nagel,S., Sillje,H.H.W. and Nigg,E.A.
  TITLE     The spindle protein CHICA mediates localization of the
            chromokinesin Kid to the mitotic spindle
  JOURNAL   Curr Biol 18 (10), 723-729 (2008)
   PUBMED   18485706
REFERENCE   5  (bases 1 to 2253)
  AUTHORS   Sauer,G., Korner,R., Hanisch,A., Ries,A., Nigg,E.A. and Sillje,H.H.
  TITLE     Proteome analysis of the human mitotic spindle
  JOURNAL   Mol Cell Proteomics 4 (1), 35-43 (2005)
   PUBMED   15561729
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474005.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_230807.4, XM_001068199.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EV779527.1, SRR8487230.83956.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2253
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..2253
                     /gene="Fam83d"
                     /gene_synonym="RGD1565583"
                     /note="family with sequence similarity 83, member D"
                     /db_xref="GeneID:311598"
                     /db_xref="RGD:1565583"
     exon            1..498
                     /gene="Fam83d"
                     /gene_synonym="RGD1565583"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..1782
                     /gene="Fam83d"
                     /gene_synonym="RGD1565583"
                     /codon_start=1
                     /product="protein FAM83D"
                     /protein_id="NP_001101266.1"
                     /db_xref="GeneID:311598"
                     /db_xref="RGD:1565583"
                     /translation="MAARCELLDDLPAACLSPCGPPNPTELFSEARRLALEQLLAGGP
                     NAWDAFLRRERLGRFLNTDEVREVLGAAERPGEDGAVVTEESFGSSHDCSSGTYFPEQ
                     SDLEPPALELGWPSFYRGAYRGATRVEAHFQPRGAGAGGPYGCKDALRQQLRSAREVI
                     AVVMDVFSDIDIFRDLQEICRKRGVAVYILLDQALLSHFLDMCMDLKVHPEQEKLMTV
                     RTITGNIYYARSGTKVVGKVHEKFTLIDGIRVATGSYSFTWTDGKLNSSNLVILSGQV
                     VEHFDLEFRILYAQSEPISSKLLSNFQISGKFDHLADQKPQSKEPTLGNLLRIRLARL
                     SSTPKKTGLDPEVPPKDRDKTKRHDSETSTISDEDYFCSHKDQLEESKVVDAATQTEP
                     GEEMAAVSLSEVGTQTSSSMMCAGTQTTVVTRAASSQATVWSKSTTTQTEADESFLPQ
                     GAQSKEESPASKMSVSRSSSLRSSSSVSSQGSLASSVSSHVSLSGTDLHTPGYPKYLG
                     LGTPHLDLCLRDSFRNLSKERQVHFTGIRSRLTQMLTVLSRRTLFTEHYLSYSPGSFT
                     RASTNLVSVRDIALYPPYQ"
     exon            499..666
                     /gene="Fam83d"
                     /gene_synonym="RGD1565583"
                     /inference="alignment:Splign:2.1.0"
     exon            667..791
                     /gene="Fam83d"
                     /gene_synonym="RGD1565583"
                     /inference="alignment:Splign:2.1.0"
     exon            792..2253
                     /gene="Fam83d"
                     /gene_synonym="RGD1565583"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtggatcgg ttctgggcac cgccatggct gctcgctgcg agttgttaga cgaccttccc
       61 gcggcctgcc tgtctccgtg cggtccgccc aaccccacgg agctgttcag cgaggcgcgg
      121 cgcctggctc tcgagcagct gctggccggc ggccccaacg cctgggatgc cttcttacgg
      181 cgcgagcggc tgggccgctt cctcaacacc gacgaggtgc gtgaggttct gggcgccgcc
      241 gagcggccgg gcgaggacgg cgcggtggtg accgaggaat cgttcggatc ctctcacgac
      301 tgctcgtcgg gcacctactt tccggagcag tcggacctgg aacctccggc gttggagctc
      361 ggctggccct ccttctaccg gggtgcctac cgcggtgcca cgcgtgtcga ggctcatttc
      421 cagccccgcg gcgcgggcgc aggcggcccg tacggctgca aggatgcact acgccagcag
      481 ctgcgctccg cccgagaggt gattgctgtg gtaatggacg ttttctcaga catcgacatc
      541 ttccgagacc tgcaggagat ctgtaggaaa cggggggtgg ctgtgtacat ccttctggac
      601 caggctctgc tctcccactt tttggacatg tgcatggatc tgaaagttca tcctgagcag
      661 gaaaagctga tgacggtgcg gaccattaca ggaaatatct actatgcaag gtcaggaaca
      721 aaggttgttg ggaaggttca tgagaagttc acactgattg acggaattcg ggtggcaacg
      781 ggctcttaca gttttacctg gaccgacggc aagttaaaca gcagtaactt ggtaattctg
      841 tctggccaag tggttgaaca ctttgatctg gagttccgga tcctgtacgc ccagtcagag
      901 cccatcagct ccaaactcct gtccaacttc cagatcagtg gcaagtttga ccatctggct
      961 gaccaaaagc cacagtcgaa ggagcccaca ctgggcaatc tgctgcgtat caggctggcc
     1021 agactctcaa gtactcccaa gaagaccggc ctggacccag aggtgccgcc aaaggacaga
     1081 gacaaaacca agcgccacga ttctgagact tccaccatca gtgatgaaga ctatttctgc
     1141 agccacaagg accagctaga ggagagcaag gtggttgatg ctgctaccca aacagagcca
     1201 ggagaagaga tggctgcagt aagcctgagc gaggtgggaa ctcagactag ttccagcatg
     1261 atgtgtgctg ggacccaaac cacagttgtc accagggcag cgagctccca ggccacagtg
     1321 tggtccaagt ccaccaccac gcagactgaa gctgacgaga gcttccttcc tcagggtgcc
     1381 cagtctaaag aagagtcacc ggcatccaag atgtcggtgt caaggtcttc cagtttgagg
     1441 tcatcctcct ctgtgtcttc ccagggctca ctggcaagct cggtcagctc ccatgtttcc
     1501 ctgtcaggca ctgatctgca cactcccgga taccccaagt acctgggtct gggcacgccc
     1561 catctggatc tgtgcctgag ggactccttc agaaacttga gtaaagagcg gcaggtccac
     1621 ttcactggca tcaggtcccg gctcacccag atgctcaccg tgctctcaag gagaacgctc
     1681 ttcacagagc actacctcag ctacagtcct gggagcttca ccagagcgtc caccaacctg
     1741 gtttctgtga gggacatagc actctatcct ccctatcagt gactgctgga ctcagccagc
     1801 cctctatccc tgccccacag agcctcacat tcttgtcctc agctcccttc tttcacctga
     1861 cactggggcc acctttgcct ttgattctgc agcactgttt gatattttta ttttttgttc
     1921 tgtcgaagcc atctattggt ttaaacacta taggtacttt tcccccattt gcacaatttt
     1981 aatattctat cattacatag gtgttttaag gttggtttga gagatatcgt tttgtatgtg
     2041 cgtgttctct gacttaatgc tttgagtcac cactgttttt taaaatcaga atcatattta
     2101 aaagttaaac actattgttc cttaactgac tttctcttga atatctgtgt tcatagtatt
     2161 aaatgagtat agacaacttt ttgtttgctc ttctttctgg caaccctggt ctttatctct
     2221 aaggatgtgt cataaataaa tgtaccatat agg
//
