LOCUS       NM_001107556            5250 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus family with sequence similarity 53, member B
            (Fam53b), mRNA.
ACCESSION   NM_001107556 XM_001054307 XM_219439
VERSION     NM_001107556.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5250)
  AUTHORS   Kizil C, Kuchler B, Yan JJ, Ozhan G, Moro E, Argenton F, Brand M,
            Weidinger G and Antos CL.
  TITLE     Simplet/Fam53b is required for Wnt signal transduction by
            regulating beta-catenin nuclear localization
  JOURNAL   Development 141 (18), 3529-3539 (2014)
   PUBMED   25183871
REFERENCE   2  (bases 1 to 5250)
  AUTHORS   Lau NC, Seto AG, Kim J, Kuramochi-Miyagawa S, Nakano T, Bartel DP
            and Kingston RE.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   3  (bases 1 to 5250)
  AUTHORS   Girard A, Sachidanandam R, Hannon GJ and Carmell MA.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001054307.1, XM_219439.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5250
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..5250
                     /gene="Fam53b"
                     /gene_synonym="RGD1310799"
                     /note="family with sequence similarity 53, member B"
                     /db_xref="GeneID:309060"
                     /db_xref="RGD:1310799"
     exon            1..231
                     /gene="Fam53b"
                     /gene_synonym="RGD1310799"
                     /inference="alignment:Splign:2.1.0"
     exon            232..490
                     /gene="Fam53b"
                     /gene_synonym="RGD1310799"
                     /inference="alignment:Splign:2.1.0"
     CDS             413..1693
                     /gene="Fam53b"
                     /gene_synonym="RGD1310799"
                     /codon_start=1
                     /product="protein FAM53B"
                     /protein_id="NP_001101026.1"
                     /db_xref="GeneID:309060"
                     /db_xref="RGD:1310799"
                     /translation="MVMILRRSLINQGADSVAHRTFIPELHTPKMSQGPTLLSCGIME
                     NDRWRDLDRKCPLQIDQPSASIWECLPEKCQDGSLWHQEAVTACAVTSLIKDLNINDH
                     NGNPSAPPSKRQCRSLSFSDEMSSCRTSWRPLGSKVWTPVEKRRCYSGGSVQRYSNGV
                     SPMQRSSSFSLPARANGLSSPCHQSSLHHRFGGQPCRGAPGSAPCGRVGDSWSPDPHP
                     VGGGRLDLQRSLSCSHEQFSFPEYCPPSANSTPASTPELARRSSGLARSRSQPCVLND
                     KKIGVKRRRPDEVQEQRPSLDLAKMAQNCQTFSSLSCLNMGVDEHSSQSPFALVSSTR
                     SWTALLSASSPGGRTPAGTPVPEPVPEPVPHSFDDQFTGQEDLSCDESDGCSLDEDCC
                     RKGEPATAWRDRGACRNSLCSLDGELDIEQIENN"
     exon            491..542
                     /gene="Fam53b"
                     /gene_synonym="RGD1310799"
                     /inference="alignment:Splign:2.1.0"
     exon            543..1321
                     /gene="Fam53b"
                     /gene_synonym="RGD1310799"
                     /inference="alignment:Splign:2.1.0"
     exon            1322..5250
                     /gene="Fam53b"
                     /gene_synonym="RGD1310799"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctgtgccct ttgggtgtct cttccaaccc cttagggttt gctcatcagc actgattcct
       61 gaggtaggat tgggcagtga acctcctgtt catttaattc ctaggaaggc tagcaaaggc
      121 cttggcccat tcaaggaaag ggagaagaca gattgggcct ggctgaggtt acattggccc
      181 aaaggtgagc tgcaataatg tagcaaaagg atgccatggc cagactagaa ggttgttgac
      241 ttcttttggc ccttcccaga gggccttgtc accagtctga gcaactgatg gggagctgtt
      301 tccgatgaca tcactcccca ggatgctcaa gtatcactgt taatcaagtc tgcccacctg
      361 aagatggcct gtacccaacc tgggatgcag cccagtgcct gaggtcctta ccatggtgat
      421 gatcctaagg agaagcctca tcaaccaggg agctgactct gtagcacaca ggaccttcat
      481 ccctgaactg cacacgccaa agatgagtca aggacctacc ctcctctcct gcggaattat
      541 ggaaaatgac agatggcgag acctggatag aaaatgccct cttcagattg accagccaag
      601 cgccagcatc tgggaatgtc tgcctgaaaa gtgtcaggat ggctctctgt ggcaccagga
      661 ggcggtgact gcctgtgcag tgaccagtct aatcaaagac ctcaacataa atgaccacaa
      721 tgggaacccc tcagctcctc ccagtaaacg ccagtgccgg tcactatcct tctctgatga
      781 gatgtccagt tgccggacgt catggcggcc cttggggtcc aaagtctgga ctcccgtgga
      841 gaagagacga tgctacagcg gaggcagtgt ccagcgctac tccaatggtg tcagccccat
      901 gcagcggagc tctagcttca gcctccctgc ccgggctaat gggctctctt caccttgcca
      961 ccagtcaagc ctgcaccacc gctttggggg acaaccctgc cgaggagcgc caggctccgc
     1021 cccttgtggg cgggtggggg atagctggag cccagaccca caccctgtgg gagggggccg
     1081 gctggacctg caaaggtctc tctcctgctc acatgagcag ttttccttcc cagaatactg
     1141 tcccccctca gccaacagca cacctgcctc aacgccagag ctggcaagac gctccagtgg
     1201 gcttgcccgc agccgctccc agccgtgtgt ccttaatgac aagaagatcg gtgtgaaacg
     1261 gcggcgtcca gacgaagtgc aggagcaaag accttcgcta gaccttgcca agatggcaca
     1321 gaactgtcag accttcagca gcctcagttg cctgaacatg ggggtggacg agcacagctc
     1381 tcagagcccc tttgccctcg tcagcagtac ccgatcctgg accgcattgc tctcagcctc
     1441 cagcccaggg ggcaggactc ccgctgggac cccagttcct gagcctgttc cggagcctgt
     1501 cccccactcc tttgatgacc agtttacggg ccaggaggac ctatcctgtg atgagtcaga
     1561 tggctgcagt ctggatgagg attgctgcag gaagggggag ccggccacag cctggcggga
     1621 caggggagcc tgcaggaaca gcctctgctc tctggacggc gagctggaca ttgagcagat
     1681 agagaacaac tgagggccat ggccatggtc tggggaggag gctttcctct aggcactcca
     1741 gaggggctcc tggctcctgg gtctggcaaa agctccccga aaaaggagcc cagccatttt
     1801 ccaaggaacc agccagcacc ctgcagtgcc caaatttgtg aaggcaactt ggctacacct
     1861 cacaggcagc agctggcctc ccaccagttc catggaacta ctgtagccta aaaacaggtt
     1921 ttcggtttgg tctcctcctc tttgctcctt atggagtgct gggtagccac tctccagcag
     1981 ggctgggcca gctgcatcct tcaagcaggg tgctagggac ctgagcaccc ttatagcccc
     2041 gctcaggttc ctcctgagga gttacccaaa gcctccttta tttagtttac tccgtgcctt
     2101 ctctcccagg tctccctggc ccaggcttgg aaaggttcgg gagacacctc ttgtagtgac
     2161 agcagaccgt gtggccttaa tccatttggg gcactggcag ggattctggg ataatccatg
     2221 tcccattttt cgggatcagg ggataggtta gggatgacca gaagccatcc atactgggta
     2281 ggcattcagt ggttgtgttg actgaaaggt gggcctgtca gctctcccac ggcaccaaga
     2341 atcacccaca tctctgccac ctcaggggct gccttggcaa ggctggcatt ggtagccttc
     2401 ctactgtctc cagtccctga gtgctgagct cagtggattc agttatgtat agagatgtca
     2461 gtgacaagat gacctcttca tagtgtcctc aggatctaca ggcaggtgca ggagtcttgg
     2521 ccctgtgtac attcctgggc agaggggtgt ctgctgcatg cttgccggct agccactctg
     2581 caggcttccc tctgtagcag tcatgttggg ggcctggaag cctccgctgc attcctggca
     2641 catggttgct tgttcacaga cactgctggc tttaatgaaa gcataccgcc attggcttca
     2701 agacacccca tcccaccccc cagtccactg atgtgagccc agccctgagg ctctcctctg
     2761 caggcccagc cacagcatgg cttgaatcac actcctgcgt gcagctcctc actcccagcg
     2821 taattcccag agggcatcca ttcaggcagc tccctcagtc ctccctgcag acatgctaca
     2881 gggctctgca ctttgggact ctggctttta gcaaacttgg catcttctgc agacaatagc
     2941 aagtgggctg gcttacacaa gtggcttgtt ttcccatacg gctaaaagta actggtgcat
     3001 tctcttgggt tctcggacat gtgatctagg cacgtttgta gttgctctgc tgtgcctacc
     3061 ctcgaggttt catcctctgc tggctgagcc caaatggttg ttacctttct cctaaagacc
     3121 tcagtgggaa tcctttgttt aaactttaat ttgtctattc accagaagaa cagaggctca
     3181 agttctgatg tataggcaac atttctttaa aatcagaccc aaaggtacag aaagccccgc
     3241 actccaataa ccccaggtca ggtagcctgg tgagtacatg tggtggtggt agggggtcca
     3301 gatggcctag ggggcactaa aaaggcaaag tagaaagcta gtgaatgcat gacatagaac
     3361 cctgccgggt gggtcacaga gggaggtagt taagagggtg tggggtgtat acaccagtgc
     3421 cctgttcccc agagagccca cagtggatga ttttgttatc tgaaataact tcatcatgct
     3481 taaagccatc cccaaggaaa agagaggctg ggccctgtcc cctggtctgc ttcacatagc
     3541 ctgctaaggc caaagcatag gccggttgcc agctgcctcc cctggggact ggggccaggg
     3601 gctcctggtg gcaggtgtgt gtcctaaggc tgttgcgtgg atgacttaat cttagactag
     3661 gtcccttgag cctggtggct gaaggacaaa caggaacttg ctgagtgaca gcttatcttt
     3721 ccttcctgcc tctaggagac tgttcccctg ggcagaaatg ttccaaacct ggggtaggca
     3781 ttggcccttt ctaacttcct caggcttctc ttgactgccc ctgtctggct aaggcctcag
     3841 cccaagcccc cagcaaaagc agccagaaaa gatggcggta gcttttctgt ccagtgtgtt
     3901 catttgctga tgttcttttc atcaagcaaa gcagattttg tctaaaaggt ttctagtcac
     3961 tattagcagt cacgtgaccc agacaagacc cactcatgga ccccactcac tggcccctca
     4021 cctctcgtct tggatatcct agaggaaggt tcacctgaga ggtcgccctg gctcccatat
     4081 actcggcacc acaggcagca ggcagactgg cttgcctcac tgggatccct ggcttcagtg
     4141 caggcaacag caaatgccat cccctcgaga ggctgagggt gggcttgttc gctcactcgt
     4201 ccaggcagcc tgaaggtcca gagcatccac cgaagccaac tgggacccaa cagggcctct
     4261 gagcacatga ctcccggtca ctccagaggc cgccaccgac acagttgctg ggaacctgac
     4321 ctgagttcag ggcagcagcc tagacagttt acatgactgc ccactcttgc cttactcatg
     4381 cgtggtgaag gtaaaagctg gccagcacct cggcctccag taggcctgta acttgctctg
     4441 cccacacatg cagatgcata ttctcagaaa gccttacttt aaaaaatttt ttttttcttt
     4501 ttgtagcagg gaagttttct aaatttgtat gcaggaagaa aagttaaata aaagaaaggt
     4561 ccacattaaa caggaaatgc ccccacccca atttctagat gagtctccta tgcagatcaa
     4621 tggccatact tttttatggg ttcattcaat gtccacagca gttagaactc acccctggat
     4681 cctgcacccc atttccactg atgtggttaa aattacttga atgatggcca cttaaaaata
     4741 taagccaggt gccagggctc agggaccctc tgcccataca gcccctgatg ctgctccttg
     4801 ccatacccat gccactggtc cagccccgcc ccgccccgcc ccaccccgcc ccccagtgct
     4861 accctgaagg aggaagggaa agatacttta aattgcaggc tgttggggct ctttaggcta
     4921 ggtagggtag cctgacagta gcatagtctc attggcaaat gaagtgcgtt gtcagtgttg
     4981 cgggggtgcc caggggtcag ggacagatgg gcctgcaggc tgtgctaggg ccacgtgtgc
     5041 tcagcggtac tgtttcaggc agtgtggtga acggagggtg cggtggtcag gcccccacca
     5101 ggacggcagc ccatgctggg tcttctcact agcaccgcac accactgcct gccttccccc
     5161 acaggccgcg actgtcttgc actacagccg ctctagtctc aggaatttgc ttgttacttt
     5221 tactgtgtaa ataaagcttc ctggttcaac
//
