LOCUS       NM_001017485            1743 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus family with sequence similarity 220, member A
            (Fam220a), mRNA.
ACCESSION   NM_001017485 XM_573355
VERSION     NM_001017485.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1743)
  AUTHORS   Ren,F., Geng,Y., Minami,T., Qiu,Y., Feng,Y., Liu,C., Zhao,J.,
            Wang,Y., Fan,X., Wang,Y., Li,M., Li,J. and Chang,Z.
  TITLE     Nuclear termination of STAT3 signaling through SIPAR
            (STAT3-Interacting Protein As a Repressor)-dependent recruitment of
            T cell tyrosine phosphatase TC-PTP
  JOURNAL   FEBS Lett 589 (15), 1890-1896 (2015)
   PUBMED   26026268
REFERENCE   2  (bases 1 to 1743)
  AUTHORS   Andreev,D.E., O'Connor,P.B., Zhdanov,A.V., Dmitriev,R.I.,
            Shatsky,I.N., Papkovsky,D.B. and Baranov,P.V.
  TITLE     Oxygen and glucose deprivation induces widespread alterations in
            mRNA translation within 20 minutes
  JOURNAL   Genome Biol 16 (1), 90 (2015)
   PUBMED   25943107
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC076392.1.
            
            [WARNING] On Jul 24, 2024 this sequence was replaced by
            NM_001017485.2.
            
            On Apr 29, 2005 this sequence version replaced XM_573355.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC076392.1, CK480486.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1743
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12p11"
     gene            1..1743
                     /gene="Fam220a"
                     /gene_synonym="Sipar"
                     /note="family with sequence similarity 220, member A"
                     /db_xref="GeneID:498145"
                     /db_xref="RGD:1561923"
     exon            1..113
                     /gene="Fam220a"
                     /gene_synonym="Sipar"
                     /inference="alignment:Splign:2.1.0"
     exon            114..1716
                     /gene="Fam220a"
                     /gene_synonym="Sipar"
                     /inference="alignment:Splign:2.1.0"
     CDS             193..972
                     /gene="Fam220a"
                     /gene_synonym="Sipar"
                     /note="STAT3-interacting protein as a repressor"
                     /codon_start=1
                     /product="protein FAM220A"
                     /protein_id="NP_001017485.1"
                     /db_xref="GeneID:498145"
                     /db_xref="RGD:1561923"
                     /translation="MRAGRGTLGVCLASVKQSQGGDLDKLACGLKRRSEKRNPSPSDV
                     PSWTDQPVADTHGKSRAMAAASSEMKRDQSKASLILHSGFKALQYLKESMGRNSTPAA
                     SLSMAVVLSSAPSEEHGAGVSGGIGDTLGSDWPAREPRTTDSCGQYLKGEAWVSGWQG
                     HPKVREVGFLRGEPLSAVPKGLGTRSELSYCSELCQLPYTYPYYEALPEDKTRCVSLD
                     HLSPVFSEETVEDEKTLSSTSDGLQIVMGLLALQSSRLTSL"
ORIGIN      
        1 gcaaggggct gacccgtacg ctgctcatct tctttgactt ggcttggcgg ctgcgcatca
       61 actttcccta cctctacatc gtagcttcca tgatgctcaa cgtgcgcctg caggttcata
      121 ttgagatcca ctgaaggcca tccttgaccg ataggcatca ccccggactc gctgcaccag
      181 agggcgcaaa gcatgagggc tgggagaggg accctgggtg tttgcctggc cagtgtgaag
      241 cagtcacaag gaggtgacct ggacaaacta gcatgtggcc ttaagagaag aagtgagaag
      301 aggaacccta gcccctcaga tgtgccttct tggacagacc agcctgtagc agacacccat
      361 ggaaagtcac gggccatggc ggcagcgtcc tcggaaatga agcgtgatca gagcaaggcc
      421 agcctcatac ttcacagcgg cttcaaagcg cttcagtatc tgaaggagtc aatggggaga
      481 aattcaactc cagcagcctc cctaagcatg gctgtggttc tgtcctctgc tccttcagaa
      541 gaacatggag ctggggtgtc cggtggcatc ggggatacac taggaagtga ctggccagca
      601 agagagccca gaaccaccga tagctgtgga cagtacctca aaggagaggc ctgggtgtca
      661 ggatggcaag gccatccaaa agtgagggaa gtgggattcc taagaggtga acccctaagt
      721 gctgtcccca aggggctagg caccagatca gaactgtctt actgctctga gctgtgccag
      781 ctgccataca cttaccccta ttatgaagct ctcccagagg acaagacgag atgtgtgtcc
      841 cttgaccact taagtcccgt gttttcagag gaaacagtag aagatgagaa aactctctca
      901 agtacgtcag atggtctgca gatagtcatg gggttactgg ctctgcaatc ttccagatta
      961 acaagtctct gatgccatag ttcaggtaca agcagaacaa taaaaatagc aaattaattt
     1021 taaagggtgt cttacagttt cttttgcatt aagtccggcg ttcgctgcag ctgttcagtt
     1081 cctgctctga ttgctgagac cgaccagaca cacctcgatg gttgatgcag agggacattt
     1141 tcgagcatgg tttcagtctt tctggaaaga cgccccaaac tgggaaaccc tctcccctgg
     1201 ggaaatgatc gatctacccc cgtataagat cagacaggaa cgaaccattt agcaccgagt
     1261 tcgatattat ggagacccat tctcaagggc tagcatcctc agcctcctgc ctcagctcac
     1321 cttgaccgtc tgacggaagt gccggtctgt aggctgtgcc gtccacttct tgtaagctgt
     1381 acttgggtca tgaagagtct tgtcacttcg gcattgcaca gactctgacc tgcagccaga
     1441 tgtcccttct cacatgctcc tcagctcctg cctgagttgg agtttgtaat ggagaagttg
     1501 caatattaaa tttaggataa ttttaaatta cagaagagtt tgagattttt ctgcggacag
     1561 aacatagatc gcaaatgaag tattttcctt tacccagacc caggacttgt gatttctttt
     1621 acattaagac cccccccccc ctccgcccaa gtaactctcc ctttgtggtt tgttgataac
     1681 tttaataaag gtcactgaat gagtggacat tttaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1741 aaa
//
