LOCUS       NM_001271134            4034 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus family with sequence similarity 168, member B
            (Fam168b), mRNA.
ACCESSION   NM_001271134 XM_001073605
VERSION     NM_001271134.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4034)
  AUTHORS   Mishra,M., Lee,S., Lin,M.K., Yamashita,T. and Heese,K.
  TITLE     Characterizing the neurite outgrowth inhibitory effect of Mani
  JOURNAL   FEBS Lett 586 (19), 3018-3023 (2012)
   PUBMED   22771904
  REMARK    GeneRIF: Considering the protein structure of Mani obtained via a
            series of bio-computational studies, we propose a
            Cdc27-Mani-APC-related signalling pathway may be involved in CNS
            axon regeneration.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Sep 1, 2012 this sequence version replaced XM_001073605.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643291.25184.1,
                                           SRR26643288.37082.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760393,
                                           SAMEA5760433 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-171               JAXUCZ010000009.1  44534354-44534524   c
            172-252             JAXUCZ010000009.1  44528530-44528610   c
            253-333             JAXUCZ010000009.1  44518548-44518628   c
            334-476             JAXUCZ010000009.1  44508335-44508477   c
            477-654             JAXUCZ010000009.1  44508061-44508238   c
            655-784             JAXUCZ010000009.1  44506636-44506765   c
            785-4034            JAXUCZ010000009.1  44502584-44505833   c
FEATURES             Location/Qualifiers
     source          1..4034
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q21"
     gene            1..4034
                     /gene="Fam168b"
                     /note="family with sequence similarity 168, member B"
                     /db_xref="GeneID:690188"
                     /db_xref="RGD:1583985"
     exon            1..171
                     /gene="Fam168b"
                     /inference="alignment:Splign:2.1.0"
     exon            172..252
                     /gene="Fam168b"
                     /inference="alignment:Splign:2.1.0"
     CDS             183..767
                     /gene="Fam168b"
                     /note="protein FAM168B; mani"
                     /codon_start=1
                     /product="myelin-associated neurite-outgrowth inhibitor"
                     /protein_id="NP_001258063.1"
                     /db_xref="GeneID:690188"
                     /db_xref="RGD:1583985"
                     /translation="MNPVYSPGSSGVPYANAKGIGYPAGFPVGYAAAPAYSPNMYPGA
                     NPTFQTGYTPGTPYKVSCSPTSGAVPPYSSSPNPYQTAVYPVRSAYPQQSPYAQQGTY
                     YTQPLYAAPPHVIHHTTVVQPNGMPATVYPAPIPPPRGSGVTMGMVAGTTMAMSAGTL
                     LTAHSPTPVAPHPVTVPTYRAPGTPTYSYVPPQW"
     exon            253..333
                     /gene="Fam168b"
                     /inference="alignment:Splign:2.1.0"
     exon            334..476
                     /gene="Fam168b"
                     /inference="alignment:Splign:2.1.0"
     exon            477..654
                     /gene="Fam168b"
                     /inference="alignment:Splign:2.1.0"
     exon            655..784
                     /gene="Fam168b"
                     /inference="alignment:Splign:2.1.0"
     exon            785..4034
                     /gene="Fam168b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggtgtctg cgcagcgtcg gcggtagcgg gggccgcggc gaggcgggcg ggaggcagcg
       61 cgggcctagc ggtcagccgc aaccgagcgt cgtctgggca ctgcccgtcg ccgagccaca
      121 cgccgtgccg gctcgggccg gcgcgcgccg gtcccggagg cgcaggctac ctacttgaag
      181 tcatgaatcc tgtttatagc cctgggtctt ctggggttcc ctatgcaaat gccaaaggaa
      241 ttggatatcc agctggtttc cctgtgggct atgcagcagc tcctgcctat tctcctaaca
      301 tgtaccctgg agcgaaccct accttccaaa caggttacac tcctggcaca ccttacaaag
      361 tgtcctgttc cccaaccagt ggggctgtgc cgccatactc ctcctccccc aatccttacc
      421 agacggctgt gtacccagtg agaagtgcct atccccagca gagcccatac gcccagcaag
      481 gcacgtacta cacacaacct ctgtatgcag cacctcctca cgtcattcac cacaccacag
      541 tggtgcagcc caatggcatg ccagcgaccg tctaccctgc tcccatccct cctcctagag
      601 gcagcggggt caccatgggc atggttgctg ggaccacaat ggccatgtca gcaggtaccc
      661 tgctgactgc tcattctcca actcctgtag cccctcaccc agtcactgtc cccacatacc
      721 gagccccagg aacacccacc tacagctatg tgcccccgca gtggtgatca ccctgcaaat
      781 taatatgtga ggatggagct gtgcagtcac ttcattgagt cccacagctg gtgctgcagg
      841 ccttgtgcct ccaaccagga ctttcttctt aatgctctcg acacttagct aaacatgact
      901 gcgtcccagc ccagcaggtc ccagctcgct agtctccagc taactctgtg ggttggtttt
      961 aaagcaaatc ctgtttgtgg actgcctggc aaatttttta gctaactgta atgataaaaa
     1021 agggagtatt attctattct gaatcatatc tagttgaatg catgtttata aaaacaaaca
     1081 aaaaagcttg ctcaatctac ctgcagtgac tgatgcaaaa cccaaaggac gggaccgtgt
     1141 tctacagcct gtgtcactca cgcacctctg tcatgtatgc tgagtctcag ttacactcgt
     1201 gcaagggatg tcctcactga agcgtcggga gtgctggagg ggactcttag ggtgctgggt
     1261 ttgccagtta tggacataga cttagagttt tcagcagcct ggtttttttg gcactgactg
     1321 actgatcctg gagggagccg cagggactgg gagagaatgt gagcctgcag cagctccaga
     1381 cagcagcagc agcagggata gtagggtccc tgcttcactt cagctggagt gtgctctggg
     1441 aagcaggggt ctacctgaag cttagcagga agtctaggag cgtggtgagc agtccagctg
     1501 gggtgaagcg aggtctgtgt gtcagtagag cagtgtctgc catctgagtt cccactgtct
     1561 gtcttacagg ataatgtctt ttgtatctgt tgggactgtt ggaaaagtcc attgtagaag
     1621 taaactgtct tcctaggagg gaagaagtca aagagaagag gcagccgcac tggaacggtg
     1681 gtgtcttttg ctttatttcg cttagggaac cattcctaat gtcccctgag aataatgagt
     1741 cagctgaaaa tacaggcgct gtgtactctc ccataaagac tgaagctggg tgctgtggag
     1801 cgcgttgtac atggaagact ggttacaagg gaataagtgt atttttaagt tagttcctca
     1861 tgtttcttgt agagaagcag ggctgtgatt atgtctaaaa atgtagaaat aatgtagctt
     1921 gtcttggggt tattcacctg aggatgacct gtcctctgtg attagtaggt gagacctgga
     1981 aagcctgcat aagtggcttt gccactcttc tgtagctgaa ggcacccagt accaagcaca
     2041 tgtggaaagt ggaaaggccg ggcagttctg gaacgcactt gcctgaaagg ctctgtggtg
     2101 ggaaagattt tgagtgcgta cgtaagaaat caagagggtt cttttcacct gaaaatatgc
     2161 ccgacttgaa tctaggagag tgtttctgtt gagtatggac caaaggggca ggacacgagg
     2221 acttttctgg gatctgtcaa gtgggggtgt gctttttatc tccttgttga accccattga
     2281 attgctgggg ctttggaagg ggtgcttgtc tctggcagct aagtcagggc ttccatgtcg
     2341 gtgtggaggt cgcctcagta gcagtcagct tagctagtgg ctgggtcacc tggatattga
     2401 accttcggtg accttacttt tatagtaatg ctctccataa tttttttagc attttatttt
     2461 atgagaagtt tatgaagatt tctgcatgaa tcagtgtgaa cagaaggttt ctcattccca
     2521 gtgtccatga acatagaata tttatggatg agtatgttta attgcttcgt gagcacttaa
     2581 gagagagtgc gtgtgtgtga ctggggtgtg cgtgcgtgtg tgtgtgtgtg tgtgtgtgtg
     2641 tgtgtgtgtg tgtgtgtgtg tgtgtacgcg cacgcgcgca tgcgaatgca tcgggggagg
     2701 gtagcccaag aaagcacaca ctgcacagag atagaaacct ttgctgtggc acatagcttg
     2761 catcgtgctt ctgtgtggga tcccacccct gtggtggatg gtgtgcagtg ctgggagtgt
     2821 tccagtctcc cagactccat agacagaagg tggtgtccag tgaataatca cgatcattgg
     2881 gacaaaggta cctgtgattt ttgcatgtgt ttgaaaaagt ctactcgccc actctcaact
     2941 gagcatagct gtcccctgcc tggaaactcc gcagggagct cccaagtctt tggacctacc
     3001 tgcagctgca cacagtgtgt gcttccacag gccctgggtt ctcaggagaa agaagagcgg
     3061 ggtttctgcc ctcctgctga tcacatcagc ctcacacact tgctctggga ctgtgtaaat
     3121 ggaatgacta tcaacacctc tgattgataa aacccgtctg tgtgtagatc ttttctgtcg
     3181 tgaagccgtc aggtcattgc tgtggagtct gctggtgaaa gatcttagtg aaaacctgag
     3241 cacatggatg gcagtaaact gtcacaggtg gtgactttaa aaacattcag ttctaggaaa
     3301 cttaaggaac agaattggct cagtacagac accccaaaac attgagaaca ttccaagaaa
     3361 gtgctttttc tgtgtatgac attcctgacg agaggtcatc agctgagtcg acaggcaggc
     3421 aggtctgata ctcactgacc tcactgctaa ggatgcgtgg atggatgcat gcatgcatgg
     3481 gtggatggat gcgtggatgg atggatggat ggatgcatgc atggatgcgt ggatggatgc
     3541 gtggatgcgt ggatggatgc atggatgcgt ggatggatgc gtggatggat ggatgcatgg
     3601 atggatgcgt ggatgcatgg atgtgtggat ggatgcgtgg atggatgcat ggatggatgg
     3661 agtatataaa gtttattttc tgttccttcc cttaggctgg ggagctttgt tcctctgctg
     3721 ctgctgtttg cagtttaagg ttgtggagta ctgaacctgt gagctccttg tctcaggaga
     3781 agtaagccca ccgtcaggat taggccagtg aggctgccgg catggaagcg gcctctggag
     3841 ctgttgtctc ttgtggtctt ccttgggaga cctgttgagc ggctgttggc ctgccagttg
     3901 ccattctggg ggtagcggct tctgagtgtt ttgcagaggc agtgttttca gcaggcgggg
     3961 aggtccccag ttctggattg gttgtcgagt gtcctgcctt ccctcagccg tacatctggt
     4021 gtcttactgt atct
//
