LOCUS       NM_001100862            2390 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus family with sequence similarity 13, member A
            (Fam13a), mRNA.
ACCESSION   NM_001100862 XM_001060651 XM_342702
VERSION     NM_001100862.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2390)
  AUTHORS   Yao,M.Y., Zhang,W.H., Ma,W.T., Liu,Q.H., Xing,L.H. and Zhao,G.F.
  TITLE     microRNA-328 in exosomes derived from M2 macrophages exerts a
            promotive effect on the progression of pulmonary fibrosis via
            FAM13A in a rat model
  JOURNAL   Exp Mol Med 51 (6), 1-16 (2019)
   PUBMED   31164635
  REMARK    GeneRIF: FAM13A expression was downregulated while miR-328
            expression was upregulated in rats with pulmonary fibrosis, and a
            miR-target relationship between miR-328 and FAM13A was observed.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2390)
  AUTHORS   Xie,J., Wu,H., Xu,Y., Wu,X., Liu,X., Shang,J., Zhao,J., Zhao,J.,
            Wang,J., Dela Cruz,C.S., Xiong,W. and Xu,Y.
  TITLE     Gene susceptibility identification in a longitudinal study confirms
            new loci in the development of chronic obstructive pulmonary
            disease and influences lung function decline
  JOURNAL   Respir Res 16 (1), 49 (2015)
   PUBMED   25928290
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On or before May 13, 2010 this sequence version replaced
            XM_342702.4, XM_001060651.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.23286.1,
                                           SRR26643296.13272.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-184               JAXUCZ010000004.1  89485721-89485904   c
            185-226             JAXUCZ010000004.1  89466692-89466733   c
            227-268             JAXUCZ010000004.1  89441928-89441969   c
            269-445             JAXUCZ010000004.1  89438874-89439050   c
            446-632             JAXUCZ010000004.1  89433691-89433877   c
            633-709             JAXUCZ010000004.1  89426113-89426189   c
            710-752             JAXUCZ010000004.1  89425293-89425335   c
            753-897             JAXUCZ010000004.1  89417696-89417840   c
            898-1102            JAXUCZ010000004.1  89409291-89409495   c
            1103-1241           JAXUCZ010000004.1  89408667-89408805   c
            1242-1323           JAXUCZ010000004.1  89407810-89407891   c
            1324-1544           JAXUCZ010000004.1  89406800-89407020   c
            1545-1628           JAXUCZ010000004.1  89406086-89406169   c
            1629-1724           JAXUCZ010000004.1  89399091-89399186   c
            1725-1808           JAXUCZ010000004.1  89397199-89397282   c
            1809-2005           JAXUCZ010000004.1  89393236-89393432   c
            2006-2107           JAXUCZ010000004.1  89392396-89392497   c
            2108-2390           JAXUCZ010000004.1  89388569-89388851   c
FEATURES             Location/Qualifiers
     source          1..2390
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q24"
     gene            1..2390
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /note="family with sequence similarity 13, member A"
                     /db_xref="GeneID:362378"
                     /db_xref="RGD:1309807"
     exon            1..184
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     CDS             156..2234
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /note="family with sequence similarity 13, member A1"
                     /codon_start=1
                     /product="protein FAM13A"
                     /protein_id="NP_001094332.1"
                     /db_xref="GeneID:362378"
                     /db_xref="RGD:1309807"
                     /translation="MACEIMPLRSSQEDERPLSPFYLSAHVSQVSSVSTTGELLERTI
                     RSAVEEHLFDVNSSADQSSEDSEPGPSSASSTPTRQRGHQFKKQDDVWYGQDKELINK
                     ENIPCGLSSCDECILNSQEAERFQDDICEYVGERSKAKRQKSSSRLAELCENHDGHLS
                     TESLSSMQTQETAEPEAVELRSSESKEAERSWRDTQHCESPAMKIQEHPSISDTKQQR
                     NQDDDDQQESFVPDLPQLDLTALCDKTWEEPIPSWQQENVESDEARLSPQAGRLIHQL
                     LDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTP
                     VQLTRRIQTLKKKIRKFEDRFEEERKYRPSHSDKAANPEVLKWTNDLAKFRKQLKETK
                     LKISEEDLTPRTRQRSNTLPKSFGSQLEKEDEKKQELVDKAIRPSVEATLEGILRKLQ
                     EKRMESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKTERQIMKPLYDRYR
                     LVKQILSRASTVPIIGSPSSKRRSPSLQPIIEGETASFFKEIKEQEEGSEDDSSTKPD
                     FTVTLKTDSSAHCFLDQLEDDADGFISPMDDKMPSKCSQDSGLSNLHSASIPELLEYL
                     QEIREEKKMIRKKLHDFEDNFFRQNGRNVQKEDRTPMAEEYNEYKHIKAKLRLLEVLI
                     SKRDADSKSM"
     exon            185..226
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            227..268
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            269..445
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            446..632
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            633..709
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            710..752
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            753..897
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            898..1102
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            1103..1241
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            1242..1323
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            1324..1544
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            1545..1628
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            1629..1724
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            1725..1808
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            1809..2005
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            2006..2107
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
     exon            2108..2390
                     /gene="Fam13a"
                     /gene_synonym="Fam13a1; RGD1309807"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcagtgtaaa tgtggaggca gccgataaat atccttgcct gcagctggag gtggagaggc
       61 agtgtcagct tcatcaggtt gtgtgttccg cgggccctgc acacagggct tgcctggaag
      121 acactcgagg atcccgtgca gattcacaca cgaggatggc ttgtgaaatc atgccgctgc
      181 gaagctcaca ggaagatgaa agacctttat cacctttcta cctgagcgct catgtatccc
      241 aagtcagcag tgtttcaaca actggagaac tcttagaaag aaccatcagg tcagcagtag
      301 aagagcacct ttttgatgtc aacagttctg cagatcaaag ttcagaggac tcagaacctg
      361 gaccatcatc agcatcttct acgcccacaa ggcagcgggg gcatcaattt aagaagcagg
      421 atgatgtttg gtatggtcaa gacaaggagc tcatcaataa ggagaatatt ccctgtggcc
      481 tcagcagctg tgatgagtgt attttgaaca gccaggaagc agaaagattc caggatgata
      541 tttgtgagta cgttggggaa agaagcaaag ccaagcgtca gaaatccagc tccaggcttg
      601 cagagctttg tgagaaccat gatggacacc tgagcacaga aagcctcagt tccatgcaga
      661 ctcaagaaac agctgaaccc gaagctgttg agctgagatc ttctgagagc aaagaagcag
      721 aaagaagctg gagagacact cagcactgtg agagccccgc gatgaagatt caggagcatc
      781 ccagtatatc tgacaccaaa caacagagga atcaggatga tgacgatcag caggagagct
      841 ttgtcccaga tctgccccag ttggacctga cagcattgtg cgataagacc tgggaagaac
      901 ccatcccttc ctggcagcaa gagaatgtag aatctgatga agctcgcctc tccccacagg
      961 ctgggcgcct gattcaccag cttctggatg aggacagtga ccccatgctg tcccccaggt
     1021 tctatgccta tgggcagagc aggcagtacc tggatgacac agaagtacct ccttctcccc
     1081 ccaattccca ttctttcatg aggcggcgaa gctcctcgct tggatcctac gatgatgagc
     1141 aagaggacct gacgcccgtg cagctcacca gaaggatcca gacccttaaa aagaagattc
     1201 ggaagtttga ggataggttt gaagaagaga ggaaatacag accctcccac agtgacaagg
     1261 cagccaaccc tgaggttctg aagtggacaa atgacttggc caaattccgg aaacagctta
     1321 aagaaacaaa attaaagatc tctgaagagg acctcacccc caggacacgg caacgaagca
     1381 atacactccc caagagtttc ggttcccagc tagaaaaaga agatgagaag aagcaagaac
     1441 tggtggacaa agccatcagg cccagcgttg aagctacact ggaagggata ctaaggaagc
     1501 tccaagagaa gcgaatggaa tccagccgtc ctgaggacat taaggatatg accaaggacc
     1561 agattgctaa tgagaaagtg gctctgcaaa aagccctgct ctactacgaa agtatccacg
     1621 ggcggccggt gacaaagact gagcgtcaga ttatgaagcc actatatgat cggtaccgac
     1681 tggtcaaaca gatactgtcc cgggccagca ctgtccccat cattggttcc ccttccagca
     1741 aacggagaag cccttcgctg cagccaatta ttgagggtga aactgcttcc ttcttcaagg
     1801 agataaagga acaagaggag ggatcagaag atgacagctc cacaaagccc gacttcactg
     1861 tcactctgaa aacagacagc agtgcacatt gctttctgga ccaacttgaa gatgacgccg
     1921 atggatttat ttcaccaatg gatgacaaaa tgccatcgaa atgcagccag gactcaggcc
     1981 tttcaaacct ccactctgct tcaatacctg aactcttgga ataccttcag gaaataagag
     2041 aagaaaagaa aatgattcga aagaaacttc atgattttga agacaatttt ttcagacaaa
     2101 atgggagaaa tgtccagaag gaagaccgta ctccaatggc tgaagaatac aatgaatata
     2161 agcacataaa ggcgaagcta cgtttgctgg aggtgctcat cagcaaaaga gacgctgatt
     2221 ccaaatccat gtgaaaggct ggtggtgtgg atgacagttc tcccagaaaa gaacagctct
     2281 ggaaggcagc agccttggag ctgtacttac aaagaaggca atcccctgcc tctgacctat
     2341 cagattgtct ccggcttcca ttgcctgcct tagaaactgc ctgcatggaa
//
