LOCUS       NM_001134834            1243 bp    mRNA    linear   ROD 04-AUG-2024
DEFINITION  Rattus norvegicus fumarylacetoacetate hydrolase domain containing
            2A (Fahd2a), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001134834 XM_001081101 XM_215851
VERSION     NM_001134834.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1243)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 1243)
  AUTHORS   Pagliarini,D.J., Calvo,S.E., Chang,B., Sheth,S.A., Vafai,S.B.,
            Ong,S.E., Walford,G.A., Sugiana,C., Boneh,A., Chen,W.K., Hill,D.E.,
            Vidal,M., Evans,J.G., Thorburn,D.R., Carr,S.A. and Mootha,V.K.
  TITLE     A mitochondrial protein compendium elucidates complex I disease
            biology
  JOURNAL   Cell 134 (1), 112-123 (2008)
   PUBMED   18614015
REFERENCE   3  (bases 1 to 1243)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Apr 23, 2021 this sequence version replaced NM_001134834.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166933.1, SRR22399481.822248.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760393,
                                           SAMN06621351 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-167               JAXUCZ010000003.1  135118487-135118653 c
            168-418             JAXUCZ010000003.1  135115939-135116189 c
            419-635             JAXUCZ010000003.1  135114441-135114657 c
            636-695             JAXUCZ010000003.1  135112705-135112764 c
            696-855             JAXUCZ010000003.1  135112301-135112460 c
            856-964             JAXUCZ010000003.1  135110984-135111092 c
            965-1052            JAXUCZ010000003.1  135110795-135110882 c
            1053-1243           JAXUCZ010000003.1  135110480-135110670 c
FEATURES             Location/Qualifiers
     source          1..1243
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q36"
     gene            1..1243
                     /gene="Fahd2a"
                     /gene_synonym="Fahd2; RGD1563674"
                     /note="fumarylacetoacetate hydrolase domain containing 2A"
                     /db_xref="GeneID:296131"
                     /db_xref="RGD:1563674"
     exon            1..167
                     /gene="Fahd2a"
                     /gene_synonym="Fahd2; RGD1563674"
                     /inference="alignment:Splign:2.1.0"
     exon            168..418
                     /gene="Fahd2a"
                     /gene_synonym="Fahd2; RGD1563674"
                     /inference="alignment:Splign:2.1.0"
     CDS             174..1115
                     /gene="Fahd2a"
                     /gene_synonym="Fahd2; RGD1563674"
                     /EC_number="5.3.2.2"
                     /note="fumarylacetoacetate hydrolase domain-containing
                     protein 2; fumarylacetoacetate hydrolase domain-containing
                     protein 2A"
                     /codon_start=1
                     /product="oxaloacetate tautomerase Fahd2a, mitochondrial"
                     /protein_id="NP_001128306.1"
                     /db_xref="GeneID:296131"
                     /db_xref="RGD:1563674"
                     /translation="MLGSGRRRLLSTLLQVQKRPCQPCRNMRLVQFQAPHLEEPHVGL
                     ESGIGGGVVDLNTFDPALPKTMVQFLERGETALSVARRALAAQLPLIPRSQVTFLAPV
                     TRPDKVICVGLNYADHCQEQNVRVPKNPIIFSKFSSSIVGPYDSIILPPESKEVDWEV
                     EMAVVIGKKGKHIKATDVMAYVAGFTVAHDVSARDWQMRNGKQWLLGKTFDTFCPLGP
                     ALVTKDTIADPHNLKISCRVNGEIVQSSNTNQMVFKTEDLIAWVSQFVTLYPGDILLT
                     GTPPGVGMFRKPPVFLKKGDEVQCEIEELGVIINKVV"
     exon            419..635
                     /gene="Fahd2a"
                     /gene_synonym="Fahd2; RGD1563674"
                     /inference="alignment:Splign:2.1.0"
     exon            636..695
                     /gene="Fahd2a"
                     /gene_synonym="Fahd2; RGD1563674"
                     /inference="alignment:Splign:2.1.0"
     exon            696..855
                     /gene="Fahd2a"
                     /gene_synonym="Fahd2; RGD1563674"
                     /inference="alignment:Splign:2.1.0"
     exon            856..964
                     /gene="Fahd2a"
                     /gene_synonym="Fahd2; RGD1563674"
                     /inference="alignment:Splign:2.1.0"
     exon            965..1052
                     /gene="Fahd2a"
                     /gene_synonym="Fahd2; RGD1563674"
                     /inference="alignment:Splign:2.1.0"
     exon            1053..1243
                     /gene="Fahd2a"
                     /gene_synonym="Fahd2; RGD1563674"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tggcgactgc gggtgggggt gggggtgcta tttcccttgg agaagagtta agtgcttgct
       61 tgctacgctc ctggctgtgg cttctctgcc cgcccctctc gacctgcagc cttgcaggca
      121 tcggctcact gcacagggag ccgggtgggt ccggccacag caaacaggct ttgatgctgg
      181 gctctggtag aaggaggttg ctgtcaactc tgctgcaggt tcagaagagg ccctgtcaac
      241 cctgcagaaa tatgagactg gtacagttcc aggcacctca cctggaagag cctcacgtgg
      301 gcctagagtc agggattggt gggggagttg tagacctaaa cacctttgac ccagcgctcc
      361 ccaagacaat ggtgcagttc ctggagcggg gagagactgc cctttcggtg gcaagaagag
      421 ccctggctgc ccagttgcca ctcatccctc ggtcacaggt gaccttctta gcccctgtca
      481 cccggccaga caaggtgata tgtgtgggct tgaattatgc agaccactgt caagaacaga
      541 acgtgcgggt gcccaagaat cccatcatct tcagcaagtt ctccagctcc atcgtggggc
      601 cctatgacag catcatcctc ccaccagaga gtaaggaagt tgactgggag gtggagatgg
      661 ccgtggtcat tgggaagaaa ggcaaacaca tcaaggccac agatgtcatg gcttacgtgg
      721 ctggcttcac tgtggctcat gatgtgagtg ctcgggactg gcaaatgaga aatggaaagc
      781 agtggttact gggaaaaact tttgatactt tctgccccct gggccctgcc ttggttacca
      841 aggataccat agcagatcca cacaatctaa agatctcctg tcgagtgaat ggggagattg
      901 tccagagcag caacaccaac cagatggtgt tcaagactga agatctgata gcctgggtct
      961 cccagtttgt cactctgtac ccaggggaca ttctcctgac tgggactcct ccaggtgttg
     1021 gcatgtttag gaagcctcct gtctttctca agaagggtga tgaagtccag tgtgagattg
     1081 aagagcttgg tgtcatcatc aacaaggtgg tgtgatggtg tcctgtaagc actggacttg
     1141 acaccaggca gaacttgtgc tcccacccag ctcactgctg gccctgccta cttaaggctg
     1201 ctcttaggta ggccatggga ataaattttc tctcaaagtt gca
//
