LOCUS       NM_001401233            1024 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus exosome component 1 (Exosc1), mRNA.
ACCESSION   NM_001401233 XM_003749119
VERSION     NM_001401233.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1024)
  AUTHORS   Staals,R.H., Bronkhorst,A.W., Schilders,G., Slomovic,S.,
            Schuster,G., Heck,A.J., Raijmakers,R. and Pruijn,G.J.
  TITLE     Dis3-like 1: a novel exoribonuclease associated with the human
            exosome
  JOURNAL   EMBO J 29 (14), 2358-2367 (2010)
   PUBMED   20531389
REFERENCE   2  (bases 1 to 1024)
  AUTHORS   Liu,Q., Greimann,J.C. and Lima,C.D.
  TITLE     Reconstitution, activities, and structure of the eukaryotic RNA
            exosome
  JOURNAL   Cell 127 (6), 1223-1237 (2006)
   PUBMED   17174896
  REMARK    Erratum:[Cell. 2007 Oct 5;131(1):188-9]
REFERENCE   3  (bases 1 to 1024)
  AUTHORS   Raijmakers,R., Noordman,Y.E., van Venrooij,W.J. and Pruijn,G.J.
  TITLE     Protein-protein interactions of hCsl4p with other human exosome
            subunits
  JOURNAL   J Mol Biol 315 (4), 809-818 (2002)
   PUBMED   11812149
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 4, 2022 this sequence version replaced XM_003749119.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EV763992.1, EV771268.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840110,
                                           SAMN12840115 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                JAXUCZ010000001.1  250694709-250694748 c
            41-156              JAXUCZ010000001.1  250694508-250694623 c
            157-231             JAXUCZ010000001.1  250692808-250692882 c
            232-320             JAXUCZ010000001.1  250688825-250688913 c
            321-354             JAXUCZ010000001.1  250687447-250687480 c
            355-405             JAXUCZ010000001.1  250686555-250686605 c
            406-490             JAXUCZ010000001.1  250685845-250685929 c
            491-1024            JAXUCZ010000001.1  250684750-250685283 c
FEATURES             Location/Qualifiers
     source          1..1024
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..1024
                     /gene="Exosc1"
                     /note="exosome component 1"
                     /db_xref="GeneID:679140"
                     /db_xref="RGD:1591855"
     exon            1..40
                     /gene="Exosc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             10..597
                     /gene="Exosc1"
                     /codon_start=1
                     /product="exosome complex component CSL4"
                     /protein_id="NP_001388162.1"
                     /db_xref="GeneID:679140"
                     /db_xref="RGD:1591855"
                     /translation="MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLTKT
                     SENGALPVVSVMRETESQLLPDVGAVVTCKVSSINSRFAKVHILYVGSTPLKNAFRGT
                     IRKEDIRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSES
                     GVQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT"
     exon            41..156
                     /gene="Exosc1"
                     /inference="alignment:Splign:2.1.0"
     exon            157..231
                     /gene="Exosc1"
                     /inference="alignment:Splign:2.1.0"
     exon            232..320
                     /gene="Exosc1"
                     /inference="alignment:Splign:2.1.0"
     exon            321..354
                     /gene="Exosc1"
                     /inference="alignment:Splign:2.1.0"
     exon            355..405
                     /gene="Exosc1"
                     /inference="alignment:Splign:2.1.0"
     exon            406..490
                     /gene="Exosc1"
                     /inference="alignment:Splign:2.1.0"
     exon            491..1024
                     /gene="Exosc1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtggcaagca tggcaccacc tgtgaggtac tgcatcccgg gcgaacgtct gtgtaacttg
       61 gaggaaggca gcccgggcag cggcacctac acccggcacg gctacatctt ttcgtcgctg
      121 gctggctgcc tgacgaagac cagcgagaat ggcgcgcttc ccgtggtatc agtaatgaga
      181 gagacagagt cccagttact tccagatgtg ggagctgtcg tcacctgtaa ggtctctagc
      241 atcaactcac gttttgccaa agtacacatc ctgtatgtag gatcgacacc acttaaaaat
      301 gcttttcggg gaactatccg caaggaagat attcgagcaa ctgaaaaaga caaggtagaa
      361 atttacaaga gtttccggcc aggtgatata gttttggcca aagttatctc cctaggtgat
      421 gcacagtcca attacctgct gacgactgct gaaaatgagt taggggttgt ggtggcccac
      481 agtgagtcag gtgtccagat ggtccccatc agctggtgtg agatgcagtg ccccaagacc
      541 cacactaaag aattccgaaa agtagccaga gtacagcctg agttcttaca aacctgagct
      601 cactctaccc acagaggggg tccactctct aaaagtacat gtgtgaaaaa agcgataaga
      661 tgccatggtc tttactgagg tacctgcagt cagctggcaa ccatctcctg aaacagtgtg
      721 cccaaaaata gtcatgccgt aatgaacacc caaggctccc gcagctgagg caggaagatc
      781 gttcgtgccc aagtttgagg ccagcctggg ctgcatagta agactctcaa ccaaaagaca
      841 aaaaagaaaa tgtacactat ttgaaacact attttgggga aactgatttt tattctctgg
      901 ctcatgaatc tcatttaaag gcactcaacc aacaaaatca tgtaatattg aaaatacctt
      961 atgcctttat atatgtgtac atatgtattt tgttatgact ggaaaaaatt cttttcattt
     1021 gtta
//
