LOCUS       NM_001024964            2420 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus exocyst complex component 3 (Exoc3), mRNA.
ACCESSION   NM_001024964 XM_341745
VERSION     NM_001024964.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2420)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2420)
  AUTHORS   Mao,L., Takamiya,K., Thomas,G., Lin,D.T. and Huganir,R.L.
  TITLE     GRIP1 and 2 regulate activity-dependent AMPA receptor recycling via
            exocyst complex interactions
  JOURNAL   Proc Natl Acad Sci U S A 107 (44), 19038-19043 (2010)
   PUBMED   20956289
REFERENCE   3  (bases 1 to 2420)
  AUTHORS   Goehring,A.S., Pedroja,B.S., Hinke,S.A., Langeberg,L.K. and
            Scott,J.D.
  TITLE     MyRIP anchors protein kinase A to the exocyst complex
  JOURNAL   J Biol Chem 282 (45), 33155-33167 (2007)
   PUBMED   17827149
REFERENCE   4  (bases 1 to 2420)
  AUTHORS   Cubelos,B., Gimenez,C. and Zafra,F.
  TITLE     The glycine transporter GLYT1 interacts with Sec3, a component of
            the exocyst complex
  JOURNAL   Neuropharmacology 49 (6), 935-944 (2005)
   PUBMED   16181645
REFERENCE   5  (bases 1 to 2420)
  AUTHORS   Vik-Mo,E.O., Oltedal,L., Hoivik,E.A., Kleivdal,H., Eidet,J. and
            Davanger,S.
  TITLE     Sec6 is localized to the plasma membrane of mature synaptic
            terminals and is transported with secretogranin II-containing
            vesicles
  JOURNAL   Neuroscience 119 (1), 73-85 (2003)
   PUBMED   12763070
REFERENCE   6  (bases 1 to 2420)
  AUTHORS   Brymora,A., Valova,V.A., Larsen,M.R., Roufogalis,B.D. and
            Robinson,P.J.
  TITLE     The brain exocyst complex interacts with RalA in a GTP-dependent
            manner: identification of a novel mammalian Sec3 gene and a second
            Sec15 gene
  JOURNAL   J Biol Chem 276 (32), 29792-29797 (2001)
   PUBMED   11406615
REFERENCE   7  (bases 1 to 2420)
  AUTHORS   Ting,A.E., Hazuka,C.D., Hsu,S.C., Kirk,M.D., Bean,A.J. and
            Scheller,R.H.
  TITLE     rSec6 and rSec8, mammalian homologs of yeast proteins essential for
            secretion
  JOURNAL   Proc Natl Acad Sci U S A 92 (21), 9613-9617 (1995)
   PUBMED   7568183
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097993.1.
            
            On Jun 27, 2005 this sequence version replaced XM_341745.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097993.1, SRR8487230.36524.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2420
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p11"
     gene            1..2420
                     /gene="Exoc3"
                     /gene_synonym="rSec6; Sec6; Sec6l1"
                     /note="exocyst complex component 3"
                     /db_xref="GeneID:252881"
                     /db_xref="RGD:621790"
     exon            1..28
                     /gene="Exoc3"
                     /gene_synonym="rSec6; Sec6; Sec6l1"
                     /inference="alignment:Splign:2.1.0"
     exon            29..219
                     /gene="Exoc3"
                     /gene_synonym="rSec6; Sec6; Sec6l1"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..2313
                     /gene="Exoc3"
                     /gene_synonym="rSec6; Sec6; Sec6l1"
                     /note="exocyst complex component Sec6; SEC6-like 1"
                     /codon_start=1
                     /product="exocyst complex component 3"
                     /protein_id="NP_001020135.1"
                     /db_xref="GeneID:252881"
                     /db_xref="RGD:621790"
                     /translation="MCKDSACFSTMKETDLEAVATAVQRVAGMLQRPDQLDKVEQYRR
                     REARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINT
                     IESLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIEQGALLQAHRKLMDLEC
                     SRDGLMCEQYRMDSGNKRDMTLIHGYFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTL
                     LVSVVRIIEREEKIDRRILDRKKQTGFVPPGRPKNWKEKMFAVLDRTVTTRIEGTQAD
                     TRESDKMWLVRHLEIIRKYVLDDLVIAKNLLVQCFPPHYDIFKNLLSMYHQALSIRMQ
                     DLASEDLEANEIVSLLTWVLNTYTSAEMMGNVELAPEVDVNALEPLLSPNVVSELLDT
                     YMSTLTSNIIAWLRKALETDKKDWSKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAA
                     QISEDLKTKVLVLCLQQMNSFLSRYKEEAQLYKEEHLRNRQHPHCYVQYMVAIINNCQ
                     TFKESIISLKRKYLKPETEESLCQSQPSMDGILDAIAKEGCSSLLEEVFLDLEQHLNE
                     LMTKKWMLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHRRVVVEYLRAVMQKR
                     ISFRSAEERKEGAEKMVREAEQLRFLFRKLASGFGEDADGHCDTIVAVAEVIKLTDPS
                     LLYLEVSTLVSKYPDIRDDHIGALLALRGDASRDMKQTIMETLEQGPMQASPNYVPIF
                     QEIVVPSLNVAKLLK"
     exon            220..439
                     /gene="Exoc3"
                     /gene_synonym="rSec6; Sec6; Sec6l1"
                     /inference="alignment:Splign:2.1.0"
     exon            440..1121
                     /gene="Exoc3"
                     /gene_synonym="rSec6; Sec6; Sec6l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1239
                     /gene="Exoc3"
                     /gene_synonym="rSec6; Sec6; Sec6l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1240..1365
                     /gene="Exoc3"
                     /gene_synonym="rSec6; Sec6; Sec6l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1466
                     /gene="Exoc3"
                     /gene_synonym="rSec6; Sec6; Sec6l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1467..1577
                     /gene="Exoc3"
                     /gene_synonym="rSec6; Sec6; Sec6l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1578..1728
                     /gene="Exoc3"
                     /gene_synonym="rSec6; Sec6; Sec6l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1729..1851
                     /gene="Exoc3"
                     /gene_synonym="rSec6; Sec6; Sec6l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1852..2013
                     /gene="Exoc3"
                     /gene_synonym="rSec6; Sec6; Sec6l1"
                     /inference="alignment:Splign:2.1.0"
     exon            2014..2141
                     /gene="Exoc3"
                     /gene_synonym="rSec6; Sec6; Sec6l1"
                     /inference="alignment:Splign:2.1.0"
     exon            2142..2395
                     /gene="Exoc3"
                     /gene_synonym="rSec6; Sec6; Sec6l1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgggaggtg gaagcagctg cgcggatgtg tacctgtggt atgacatgtg caaagattct
       61 gcctgctttt cgactatgaa ggagacagac ctggaggctg ttgcaacagc agtccaaagg
      121 gtggctggga tgcttcagcg cccagaccag ctggacaaag tggagcagta tcgcagaagg
      181 gaggctcgga agaaggcctc tgtggaggcc aggctaaagg ccgcaatcca gtctcaacta
      241 gatggcgtcc gcacaggcct aagccaactg cacaatgcac tgaatgatgt caaggatatc
      301 cagcagtcac tggctgatgt gagcaaggac tggaggcaga gcatcaacac catcgagagt
      361 ctcaaggacg taaaagacgc agtggtgcag cacagccagc tggctgcagc tgtggagaac
      421 ctcaagaaca tattctctgt gcctgagatt gtgagggaga cccaagatct catcgagcaa
      481 ggggctctcc tgcaggccca ccggaagcta atggatctgg agtgctcccg ggatgggcta
      541 atgtgtgagc agtaccgcat ggacagtggg aacaaacggg acatgaccct cattcatggc
      601 tacttcggta gcacacaggg gctctctgac gagctggcca agcagctgtg gatggtgctg
      661 caaagatcgc tggtcactgt ccgccgggat cccaccttgc tggtctccgt ggtcaggatc
      721 attgaaaggg aagaaaaaat tgacaggcgg atacttgatc gaaaaaagca aactgggttt
      781 gttcctcctg gaaggcccaa aaactggaag gaaaaaatgt ttgccgtctt ggacagaact
      841 gtgacgacta gaatcgaagg cacgcaggcg gacaccagag aatctgacaa gatgtggctc
      901 gtgcgccacc tggagatcat taggaagtac gtcctggatg acctcgtcat cgccaagaac
      961 ctgctggtgc agtgcttccc tcctcactat gacatcttta agaacctcct gagcatgtac
     1021 caccaggcct tgagcattcg gatgcaggac ctcgcctcag aggaccttga ggccaacgag
     1081 attgtgagcc tcttgacctg ggtcctaaat acctacacca gtgcagagat gatggggaat
     1141 gtggagctgg ccccagaggt ggacgttaat gccctggaac cgctcctctc accaaacgtg
     1201 gtctctgagc tgctcgacac atacatgtca acactcacgt ccaacatcat tgcctggctt
     1261 cggaaagcac tggagacaga caagaaagac tggagcaaag agacggagcc ggaagcagac
     1321 caggacggct attatcagac gacacttcct gccattgtat tccagatgtt tgaacagaat
     1381 cttcaagttg ctgctcaaat aagtgaagat ttgaaaacaa aggtattagt tttgtgtctt
     1441 cagcaaatga attctttcct aagtagatac aaagaggaag cccagcttta caaagaggag
     1501 cacctgagaa accggcagca cccacactgt tacgtgcagt acatggtcgc catcatcaat
     1561 aactgccaga ccttcaaaga atccatcatc agtctgaaaa gaaaatacct aaaacccgaa
     1621 acagaggaaa gcctgtgtca gagtcagccc agcatggatg ggattctaga tgccattgct
     1681 aaggaaggct gcagcagtct gctagaggag gtcttcctgg atctagagca acatctgaat
     1741 gagctaatga caaagaagtg gatgttagga tcaaatgctg tggacatcat ctgtgtcacc
     1801 gtagaagact acttcaatga cttcgccaaa attaaaaagc catacaaaaa gaggatgaca
     1861 gctgaggcac acaggcgtgt ggtggtggaa tacctgcggg ctgtcatgca gaagcgtatt
     1921 tcctttcgga gtgctgaaga gcgcaaggag ggtgctgaga agatggtcag agaggcggaa
     1981 cagctccgct tcctgttccg gaagctggca tctggatttg gtgaggatgc agatggacac
     2041 tgtgacacaa tcgttgcagt ggcagaggtc attaagctca cggacccgtc tctgctctac
     2101 ctagaagtct caactctggt cagcaaatat ccagacatca gagatgacca tattggtgcg
     2161 ctgctggcac tgcgaggaga cgccagccgg gacatgaagc agaccatcat ggagacactg
     2221 gagcagggcc ccatgcaagc gagccccaac tatgtgccca tcttccagga gattgtggtg
     2281 cccagtctga acgtggcaaa gctccttaag tagccctgtc ctccctgctg tcctgtgtgt
     2341 ctttactttg tggctttcct attgtcactg tattaaaaca aaagtccgtc tcttgaaaaa
     2401 aaaaaaaaaa aaaaaaaaaa
//
