LOCUS       NM_001107973            2016 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus exonuclease 5 (Exo5), mRNA.
ACCESSION   NM_001107973 XM_001053928 XM_233480
VERSION     NM_001107973.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2016)
  AUTHORS   Sparks JL, Kumar R, Singh M, Wold MS, Pandita TK and Burgers PM.
  TITLE     Human exonuclease 5 is a novel sliding exonuclease required for
            genome stability
  JOURNAL   J Biol Chem 287 (51), 42773-42783 (2012)
   PUBMED   23095756
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473968.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001053928.1, XM_233480.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EV767865.1, FM062200.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132263, SAMD00132264
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2016
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2016
                     /gene="Exo5"
                     /gene_synonym="Dem1; RGD1309802"
                     /note="exonuclease 5"
                     /db_xref="GeneID:313563"
                     /db_xref="RGD:1309802"
     exon            1..520
                     /gene="Exo5"
                     /gene_synonym="Dem1; RGD1309802"
                     /inference="alignment:Splign:2.1.0"
     exon            521..2016
                     /gene="Exo5"
                     /gene_synonym="Dem1; RGD1309802"
                     /inference="alignment:Splign:2.1.0"
     CDS             551..1672
                     /gene="Exo5"
                     /gene_synonym="Dem1; RGD1309802"
                     /note="defects in morphology protein 1 homolog; defects in
                     morphology 1 homolog"
                     /codon_start=1
                     /product="exonuclease V"
                     /protein_id="NP_001101443.1"
                     /db_xref="GeneID:313563"
                     /db_xref="RGD:1309802"
                     /translation="MAETGEEETASAEASGFSDISDSELVEFLDLEDAKESAVSLSKP
                     GPSSELPGKDDKPVSLQNCKRGLDVLSPMDRFHLKYLYVTDLCTQDWCELQMVYGKEL
                     PGSLTPEKAAVLDIGASIHLAKELELHDLVTVPTTTKEDAWAVKFLNILSMVPTLQSE
                     GRIREFPVFGEVEGIFLVGVIDELHYTSKGELELAELKTRRRPVLPLSAQKKKDYFQV
                     SLYKYIFDAMVQGKVTPASLIHHTKLCVDKPLGPSVLRHARQGGVSVKSLGDLMELVF
                     LSLTLSDLPAIDTLKLEYVHQETATTLGTEIVAFEEKEVKSKVRHFVAYWMGRRDPQG
                     VDVEEAWKCRTCDYVDICEWRRSSGMLSSLREPKAKKLK"
ORIGIN      
        1 ggggtgaagg gctaaggggc cgccccttcc aggcacgccc ctccttcctg gttcttgctg
       61 tgtattttgg gctgggcacc acccgagact gagtcttcgc gcgtgggtac accatgggga
      121 caggagctgg gagctgagtg ggaagcacag gtctgcctgc gtggaaggcc tgtaacgagt
      181 caggacgcag aggatgaagg cagtggcagg cagacggaag ctatcagcga ggcagggtct
      241 ccgacctcag gctgcggctg ggaacctgga gggcagaact gaccgcctgg agaccttacc
      301 ctggagaggc cattgttagg agaatttatg acaggcgagc tgttcttgca gcgtgactca
      361 agtggaaata ccataatgtg agggagtggt caggtgaaaa ggacacaagt ccacattcca
      421 tcatagcaag gtcccaagta cctacgcatc tcccctcggc tcgctttgcc attttaattc
      481 atgctcttcc ctgcgaggag ggaaatcaac taaggcccag gtccctactt gttcaatcta
      541 ggaccgtacc atggctgaga ccggggaaga ggagacagca tcagcagaag cctcagggtt
      601 ctcagacata agtgactccg agttagtaga gtttctggac ctggaagatg ccaaagaatc
      661 agctgtttca cttagcaagc ctggcccttc ttctgaactc cctgggaagg atgacaaacc
      721 tgtaagcttg cagaactgta aaaggggatt ggatgtcctg tcacccatgg atagattcca
      781 cttgaagtat ttatatgtca ctgacctgtg tactcaggac tggtgtgagt tgcagatggt
      841 gtatgggaag gaacttcctg gttctttgac acctgagaag gcagctgttt tggacattgg
      901 tgctagcatc cacctagcaa aagaactaga acttcatgac cttgtgacag tccccaccac
      961 cactaaagaa gatgcttggg cagttaagtt tctgaacata ctatcaatgg ttcctaccct
     1021 acagtcagaa gggcgcatca gagagtttcc agtgtttggg gaagtggagg gaatctttct
     1081 tgttggagtg attgatgagt tgcactacac atccaagggg gaactggagc tggctgaact
     1141 caagacacga aggcgccctg tgctccccct gtcagctcag aaaaagaaag actattttca
     1201 agttagtcta tacaaatata tctttgatgc catggtacaa gggaaggtga ctcctgctag
     1261 tctaatccac cacactaaat tgtgtgtaga caagccactg gggccttcag tgctgaggca
     1321 tgccaggcaa ggaggtgtgt ctgtaaaatc tctgggcgac cttatggaac tggttttctt
     1381 atctcttaca ctgtctgatc tcccagctat tgatacccta aaacttgagt atgtccatca
     1441 agagactgcc actacattgg gcacagagat tgtagccttt gaagagaaag aggtgaaaag
     1501 caaggtgcgg cattttgtgg cctactggat gggccgccga gaccctcaag gcgttgatgt
     1561 ggaagaggca tggaagtgtc ggacctgtga ctatgtggac atctgcgagt ggaggaggag
     1621 cagtggaatg ctcagctctt tgagggagcc caaagccaag aagttgaagt gaatgaaggt
     1681 acactttcag agatgttgat cgtttctgtt acaatacacc tgtgtaagag gaccagtctc
     1741 tcagcttggt gttcatggat aatgttgatt atttttatgt ttacaatctt gaataacatt
     1801 ccaacccagg gccaaggata aggaatgagt ggagagatgt ggtgttagag tgaccttgga
     1861 gctttgagat aaattgcaaa gaagatgcac atattgtctg caactaatca ctagtcactg
     1921 tcggctcaag gaagttcttt ggattctgat aaatctttat ttttttcttg ataatttttt
     1981 ttttacattt tttacaataa aaatgaaatg ctatct
//
