LOCUS       NM_001107761            3435 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus exonuclease 3'-5' domain containing 1 (Exd1),
            mRNA.
ACCESSION   NM_001107761 XM_001080847 XM_230476
VERSION     NM_001107761.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3435)
  AUTHORS   Yang,Z., Chen,K.M., Pandey,R.R., Homolka,D., Reuter,M.,
            Janeiro,B.K., Sachidanandam,R., Fauvarque,M.O., McCarthy,A.A. and
            Pillai,R.S.
  TITLE     PIWI Slicing and EXD1 Drive Biogenesis of Nuclear piRNAs from
            Cytosolic Targets of the Mouse piRNA Pathway
  JOURNAL   Mol Cell 61 (1), 138-152 (2016)
   PUBMED   26669262
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473949.1.
            
            [WARNING] On Aug 9, 2024 this sequence was replaced by
            NM_001107761.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_230476.4, XM_001080847.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760389
                              [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3435
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q35"
     gene            1..3435
                     /gene="Exd1"
                     /gene_synonym="Exdl1; RGD1561009"
                     /note="exonuclease 3'-5' domain containing 1"
                     /db_xref="GeneID:311334"
                     /db_xref="RGD:1561009"
     exon            1..749
                     /gene="Exd1"
                     /gene_synonym="Exdl1; RGD1561009"
                     /inference="alignment:Splign:2.1.0"
     exon            750..932
                     /gene="Exd1"
                     /gene_synonym="Exdl1; RGD1561009"
                     /inference="alignment:Splign:2.1.0"
     CDS             800..2488
                     /gene="Exd1"
                     /gene_synonym="Exdl1; RGD1561009"
                     /note="exonuclease 3'-5' domain-like 1; exonuclease 3'-5'
                     domain-containing protein 1"
                     /codon_start=1
                     /product="piRNA biogenesis protein EXD1"
                     /protein_id="NP_001101231.1"
                     /db_xref="GeneID:311334"
                     /db_xref="RGD:1561009"
                     /translation="MDASSDYHFLNQILWRRVKLTLVSGIFEGVLQHVDPNKIVVLKN
                     VKNIESGRSVPGVKMFFGHEILNVELMDEAEGASGEKVNSVSINTERAGMEKMKKEDL
                     NVCEPASPAPEVPTSSLLSDLKYCPSEEEEVTYTVIDQFQQKFGAAMLHIKKQSVLSV
                     AAEGANVCRHGKLCWLQVATNSRVYLFDIFLLGSRAFNNGLQMILEDKRILKVIHDCR
                     WLSDCLSHQYGIMLSNVFDTQVADVLQFSMETGGFLPNCISTLQECLIRHLKVAPKYL
                     LFLEERQKQIQENPEVWLTRPLPPSLLKILALETAYLLPLRLVLLDEVMSDLTTLVDA
                     YLNTYRDGSADRLAGTEPACMELPAELLQLQDFQKQRRERAAKEYRVNAQGLLIRTLL
                     HPKEPGARTVGKEEHIQGFLFCKTSGVDRVPRFICHDSHKDENYLDKESKQTTEKSQI
                     VPPWKEGEKSKPVCGEPAGSEDPRAQSLPPRQAFQSQFSLKEEIEQLLLVENKGALTS
                     SNEDTLVSPSLSQEAWEAPSESSHLPENAVVSALPPCPALEKTDSWISPSLNLF"
     exon            933..1001
                     /gene="Exd1"
                     /gene_synonym="Exdl1; RGD1561009"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1056
                     /gene="Exd1"
                     /gene_synonym="Exdl1; RGD1561009"
                     /inference="alignment:Splign:2.1.0"
     exon            1057..1184
                     /gene="Exd1"
                     /gene_synonym="Exdl1; RGD1561009"
                     /inference="alignment:Splign:2.1.0"
     exon            1185..1243
                     /gene="Exd1"
                     /gene_synonym="Exdl1; RGD1561009"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1330
                     /gene="Exd1"
                     /gene_synonym="Exdl1; RGD1561009"
                     /inference="alignment:Splign:2.1.0"
     exon            1331..1435
                     /gene="Exd1"
                     /gene_synonym="Exdl1; RGD1561009"
                     /inference="alignment:Splign:2.1.0"
     exon            1436..1516
                     /gene="Exd1"
                     /gene_synonym="Exdl1; RGD1561009"
                     /inference="alignment:Splign:2.1.0"
     exon            1517..1660
                     /gene="Exd1"
                     /gene_synonym="Exdl1; RGD1561009"
                     /inference="alignment:Splign:2.1.0"
     exon            1661..1852
                     /gene="Exd1"
                     /gene_synonym="Exdl1; RGD1561009"
                     /inference="alignment:Splign:2.1.0"
     exon            1853..3435
                     /gene="Exd1"
                     /gene_synonym="Exdl1; RGD1561009"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcgtgcccgg aatgaatcag ccgggcggct gctggagtcc aaagggaggc aggccccgcc
       61 cccggaacca gggatgccgc cggccttaaa gcgacaatac cacggtggcg ctagggacag
      121 cacttaaagg gcagtgcggc ctctcctctg tttttagaca aaccagagac agactcccta
      181 gagtagctga caggtttctc acaagactca agcaccagga atctcaccct acaagtgaca
      241 gggattcagg agagaaacaa aacccacaaa accagtggga aaaccctaag gtggatcccc
      301 agagaagttc agctgagatt tatgcactct tcctgctcgc ttccgcacgc tcggtctgtc
      361 tgtctttctg tctctctgtc tctctctgtc tctctctctc tgtctctctc tgtctgtctg
      421 tctctctctc tctctttctc tctctctcat ttctcttcct cctttctcct cacccttttc
      481 tccctctccc actctcactc ccctggtcct aagaatagtg ttgggagtct ccttggcacc
      541 ctcaatcccc cccccaactc cccctcccgc atgcctatgg actgcatctt ttctgtgcct
      601 cttcccctgg ccgtagaggg gcgctgggag ccgcccgggg ttcgcaaggc tattggttgc
      661 atcttttctg cgctctttac cccggccgca gggggcgctg ggagccagct cgaggctgct
      721 cgctgattgg ctcctccaga aagaggcaat gtttggatgc tgaagttgga ctctgaaggc
      781 tactttggaa tgaaaaagca tggatgccag cagtgactac catttcctca accagatttt
      841 gtggagaagg gtgaagctca cactggtgtc tggcatcttt gagggcgtgc tccagcatgt
      901 ggatcctaac aagattgttg tcctgaaaaa cgtgaagaac atagagtcag gccgaagtgt
      961 cccaggagtg aaaatgtttt tcgggcatga gattttgaat gtggaactaa tggatgaagc
     1021 agaaggtgca tcgggagaaa aggtgaactc tgttagcata aatacagaac gagctggaat
     1081 ggagaaaatg aaaaaggaag acttaaatgt atgtgagcct gcctcacctg caccagaggt
     1141 gccaaccagc tctctcctca gtgacctcaa gtactgccca tcagaggaag aggaggtgac
     1201 gtatacggtc attgatcagt tccagcagaa gtttggtgct gcgatgctcc acattaagaa
     1261 gcagagtgtc ctgagtgtcg ctgctgaagg agctaatgtg tgtcgccatg ggaaactctg
     1321 ttggcttcag gtagccacaa acagccgagt ttacttgttt gatattttcc ttctgggaag
     1381 ccgtgctttc aacaatggac ttcagatgat cttagaagac aagagaatct taaaggttat
     1441 ccacgattgt cgctggctgt ctgattgcct gtctcatcag tatggaatca tgctgagcaa
     1501 tgtctttgac acacaggtag ccgatgtcct tcagttttct atggaaacgg gtggctttct
     1561 tccaaactgt atcagtactt tgcaggagtg tttaatcaga caccttaaag ttgcccccaa
     1621 ataccttttg tttttagaag agagacagaa acagattcag gaaaatccag aagtatggct
     1681 gacaagaccc cttccaccct ctttattgaa aatcttggcc ctggaaacag cctacctgct
     1741 tccccttcgg ctggtgctcc tggatgaggt gatgtcagat ttgaccacac tggtggatgc
     1801 gtacctgaac acctaccggg atgggtctgc agaccggctt gccggcacag agcctgcgtg
     1861 tatggagctg cctgcagagc ttcttcaact ccaggacttc cagaagcagc gcagagagag
     1921 agctgcaaag gagtacagag tgaacgcaca gggcctcctc ataaggacgc tgctacaccc
     1981 aaaggagcca ggggctcgca cagtggggaa agaggagcac atccagggtt tcttattttg
     2041 taagacgtct ggtgtagacc gggttcctcg ctttatatgt cacgactctc ataaggatga
     2101 gaattatttg gataaagagt ctaaacaaac cacagaaaag tcacaaatcg tacctccctg
     2161 gaaggaaggc gaaaagagca aaccagtgtg tggggagcca gctgggtcag aagacccgag
     2221 agcccagtcc ctgcctccca gacaggcatt tcagtcacag ttttctttaa aagaggagat
     2281 agaacagttg ctgttggtgg aaaataaagg agctttaaca agctcaaatg aagacactct
     2341 ggtgtcgcct tctctttctc aggaagcctg ggaagcacca agtgaaagct cccatcttcc
     2401 cgaaaatgct gtggtttctg cacttccacc ctgtccagcc ctggagaaga cagattcatg
     2461 gataagtccg tctctaaatc tgttttagga ttgtcactga ggccagagtc cctgtgagtt
     2521 tctcatgggg tcagttggtt aggtctcagc cacaggcttc aggggaaaat ggtggcctta
     2581 ggcttagtgc tgaagcccgc tgtctggatc aggagggtcc taagagcagc aatgggtgag
     2641 gtcattccga ctgtgtgagg aaatagtccc ggtagctgat acggacttct catctttagg
     2701 tttagaggat ttaaagcgaa gctcggctca gcgcctggaa ggatctggtt taggaatgtt
     2761 gcagggcagc tcttgtggtg gcagagagct gggcggctac acacaccacc agttcagcac
     2821 cagcagacag aaggtgtatg cttttatttg tttgggtttg ttctgtttta cctttagatt
     2881 gaagtagatc taaaaacccc ttacatacag gttagaaatg tattttgttg acttcacaag
     2941 taccgctctt ccttaagacc ttatttgagg gctggagaga tggctcagtg gttaagaaca
     3001 ctgactactc ttccaaaggt cgtgagttca aatcccagca accacatggt ggctcacaac
     3061 catctgtaat gagacctgat accctcttct ggtgtctctg aggacagcta cagtgtacac
     3121 agtatatata tataaaatat aataaataaa taaatcttta aaaaaaagac cttggggttg
     3181 gggatttagc tcagtggtag agcatttgcc tagcaagctc aaggccctgg gtttggtccc
     3241 cagctctgaa aaaaaaaaaa aaaaacctta tttgaactgt gcacttttgc acatcacatc
     3301 aggggcagag aacaggtgat gtcactgtgg gggcattccc ccaacttcct ttatatttca
     3361 ttcatcttaa gagagcagag tgctagcttc tttgttgtta tttccttctg gtaaatgtaa
     3421 aatttgagtt cattg
//
