LOCUS       NM_001163156            6792 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ETS variant transcription factor 1 (Etv1),
            transcript variant 1, mRNA.
ACCESSION   NM_001163156
VERSION     NM_001163156.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6792)
  AUTHORS   Shekhar,A., Lin,X., Lin,B., Liu,F.Y., Zhang,J.,
            Khodadadi-Jamayran,A., Tsirigos,A., Bu,L., Fishman,G.I. and
            Park,D.S.
  TITLE     ETV1 activates a rapid conduction transcriptional program in rodent
            and human cardiomyocytes
  JOURNAL   Sci Rep 8 (1), 9944 (2018)
   PUBMED   29967479
  REMARK    GeneRIF: A cardiomyocyte-autonomous, ETV1-dependent pathway that is
            responsible for specification of rapid conduction zones in the
            heart was identified and ETV1 is sufficient to promote a
            His-Purkinje system transcriptional and functional program upon
            ventricular myocytes.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6792)
  AUTHORS   Yang,L., Fox,S.A., Kirby,J.L., Troan,B.V. and Hinton,B.T.
  TITLE     Putative regulation of expression of members of the Ets variant 4
            transcription factor family and their downstream targets in the rat
            epididymis
  JOURNAL   Biol Reprod 74 (4), 714-720 (2006)
   PUBMED   16394217
  REMARK    GeneRIF: The data suggest that ETV4 family members regulate their
            own expression, and that they regulate transcription of a subset of
            genes that are dependent upon testicular luminal fluid factors.
REFERENCE   3  (bases 1 to 6792)
  AUTHORS   Firlej,V., Bocquet,B., Desbiens,X., de Launoit,Y. and
            Chotteau-Lelievre,A.
  TITLE     Pea3 transcription factor cooperates with USF-1 in regulation of
            the murine bax transcription without binding to an Ets-binding site
  JOURNAL   J Biol Chem 280 (2), 887-898 (2005)
   PUBMED   15466854
REFERENCE   4  (bases 1 to 6792)
  AUTHORS   Pastorcic,M. and Das,H.K.
  TITLE     Ets transcription factors ER81 and Elk1 regulate the transcription
            of the human presenilin 1 gene promoter
  JOURNAL   Brain Res Mol Brain Res 113 (1-2), 57-66 (2003)
   PUBMED   12750007
REFERENCE   5  (bases 1 to 6792)
  AUTHORS   Arber,S., Ladle,D.R., Lin,J.H., Frank,E. and Jessell,T.M.
  TITLE     ETS gene Er81 controls the formation of functional connections
            between group Ia sensory afferents and motor neurons
  JOURNAL   Cell 101 (5), 485-498 (2000)
   PUBMED   10850491
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB547717.1, JAXUCZ010000006.1, BC168860.1, CB718897.1 and
            BQ195622.1.
            
            On Sep 11, 2014 this sequence version replaced NM_001163156.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760389
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                CB547717.1         1-37
            38-4048             JAXUCZ010000006.1  61404308-61408318
            4049-4611           CB547717.1         38-600
            4612-4706           BC168860.1         583-677
            4707-5234           CB718897.1         4-531
            5235-6139           BC168860.1         1137-2041
            6140-10150          JAXUCZ010000006.1  61404308-61408318
            10151-10761         BQ195622.1         54-664              c
            10762-10763         JAXUCZ010000006.1  61408942-61408943
            10764-10802         BQ195622.1         1-39                c
FEATURES             Location/Qualifiers
     source          1..6792
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q21"
     gene            1..6792
                     /gene="Etv1"
                     /note="ETS variant transcription factor 1"
                     /db_xref="GeneID:362733"
                     /db_xref="RGD:1312007"
     exon            1..120
                     /gene="Etv1"
                     /inference="alignment:Splign:2.1.0"
     exon            121..252
                     /gene="Etv1"
                     /inference="alignment:Splign:2.1.0"
     CDS             208..1641
                     /gene="Etv1"
                     /note="isoform a is encoded by transcript variant 1; ets
                     variant gene 1"
                     /codon_start=1
                     /product="ETS translocation variant 1 isoform a"
                     /protein_id="NP_001156628.1"
                     /db_xref="GeneID:362733"
                     /db_xref="RGD:1312007"
                     /translation="MDGFYDQQVPYVVTNSQRGRNCTEKPTNVRKRKFINRDLAHDSE
                     ELFQDLSQLQETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSELGSA
                     CSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNTAHTPK
                     PDRAFPAHLPPSQSIPDSTYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEP
                     NIPFPPQGFKQEYHDPVYEHTTMVGGAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIY
                     MRQESFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGS
                     LQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRS
                     LRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPL
                     SHFDESMTYMPEGGCCNPHPYNEGYVY"
     exon            253..340
                     /gene="Etv1"
                     /inference="alignment:Splign:2.1.0"
     exon            341..388
                     /gene="Etv1"
                     /inference="alignment:Splign:2.1.0"
     exon            389..442
                     /gene="Etv1"
                     /inference="alignment:Splign:2.1.0"
     exon            443..572
                     /gene="Etv1"
                     /inference="alignment:Splign:2.1.0"
     exon            573..761
                     /gene="Etv1"
                     /inference="alignment:Splign:2.1.0"
     exon            762..1009
                     /gene="Etv1"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1078
                     /gene="Etv1"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1147
                     /gene="Etv1"
                     /inference="alignment:Splign:2.1.0"
     exon            1148..1317
                     /gene="Etv1"
                     /inference="alignment:Splign:2.1.0"
     exon            1318..1419
                     /gene="Etv1"
                     /inference="alignment:Splign:2.1.0"
     exon            1420..6778
                     /gene="Etv1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgaattcag ctctgtcaga ggcgctttcg gcttccaagg ggaagtgctg ggcaataatt
       61 aatgttttta ttaaatttgg agggaatttt ttgcagccgt tcgcctagcg tggccttcag
      121 gttgatagaa gtccagatcc cgaggaaatc tgcagctaaa tgctcaaaat ataaaacact
      181 gagctagtat ttgagaagag gagcagaatg gatggatttt atgaccagca agtgccttac
      241 gtggtcacca acagtcagcg tgggagaaac tgtaccgaga aaccaacaaa tgtcaggaaa
      301 agaaaattca ttaacagaga tctggctcat gattcagaag aactctttca agatctgagt
      361 cagttacaag aaacatggct tgctgaagct caggtacctg acaatgatga gcagtttgtg
      421 ccagactatc aggccgaaag tttggctttt catggcctac cactgaaaat caagaaagaa
      481 ccccacagcc catgttcaga actcgggtct gcttgcagcc aagagcagcc ctttaaattc
      541 agctatggag aaaagtgcct gtacaatgtc agtgcctatg atcagaagcc acaagtggga
      601 atgaggccct ccaatccccc aacaccatcc agcactccag tgtccccact acatcatgca
      661 tctccaaaca cagctcatac tccgaaacct gaccgggcct tcccagctca cctcccgcct
      721 tcccagtcca taccagacag cacctacccc atggaccaca gatttcgccg ccagctttct
      781 gaaccctgta actctttccc tcctttgcca acaatgccaa gggaagggcg tcctatgtac
      841 caacgccaga tgtctgagcc aaacatcccc ttcccaccac aaggcttcaa gcaggagtac
      901 cacgacccag tctatgaaca taccaccatg gttggcggtg cagccagcca aagctttccc
      961 cctcctttga tgatcaaaca ggaacccaga gactttgcat atgattcaga agtgcctagc
     1021 tgccactcca tttatatgag gcaagaaagc ttcctggctc atccaagcag aacagaaggc
     1081 tgcatgtttg agaagggtcc caggcagttc tatgatgaca cctgtgtcgt cccggagaag
     1141 ttcgatgggg acattaagca agagccagga atgtaccggg aaggtcccac gtaccagagg
     1201 cgaggatcgc ttcagctctg gcagtttctg gtagctcttc tggatgaccc ttcaaattct
     1261 cattttattg cctggactgg gcgaggcatg gaatttaaac tgattgagcc tgaagaggtg
     1321 gcccgacgtt ggggcattca gaagaacagg ccagctatga actatgacaa acttagccgt
     1381 tctctccgct attattatga gaagggaatc atgcaaaagg tggctggaga aagatatgtc
     1441 tacaaatttg tgtgtgaccc ggaagccctt ttctccatgg cctttccgga taatcagcgc
     1501 cccctgctga agacggacat ggaacgtcac atcaacgaag aggacacggt gcccctgtct
     1561 cactttgatg agagcatgac ctacatgcca gaagggggct gctgcaaccc ccacccttac
     1621 aacgaaggat acgtgtacta acctaacagt caagcaaggc accccgtgct tcgccttttt
     1681 ttttttttca agatacagag aatctccgaa ttctcttaca atgtttgttt tatttctgtt
     1741 gtttgtattt tactttttaa ataataatac aaaagggggc ttttcctgtt gcattattct
     1801 atggtctgcc atggactgcg cactttattt gagggtgggt gggaataatc tagacattca
     1861 ttctttgtaa caggaagatg gtgggtgaac gggcagaggg agctgaggga ttccttttta
     1921 cttaggcttg ggatggggtc ctacaggttt tctgtatgat gaagctatat catgtttgtt
     1981 cgatttctta ataacgtaag ataattttcc ctgggtatct acggtacagt tgatttcacg
     2041 ttgtgtaaat atcttcttgg agaccatttg ccttgggcat ttccccatca gtactgagtc
     2101 tctgcaggtg tacaaaaaaa aaaaaaaaat ctactgtaaa tggcagtttc atgttagaaa
     2161 tgactgtttt tgcacctctt gtaaaaaaaa gaaaaaagaa tatttagcaa ttgcatttgt
     2221 tgttctttct gtttcatact gctttacaga tgacttgtag agaatgacca taaatgtggg
     2281 caattctctc agaagttgag taatccccat aactgtaaat gagggccaca gttttggact
     2341 ctggctctaa ctgagtcaca ggccagtagc attacatgga tctggtgtca tcttgctgtt
     2401 ttggtactac aagtactgtc ttttaaatat gttgatgccc atttcactta aataatgaca
     2461 ttcatgatcc tttggaatct tcatgtaagt gttaaagctg ggatcacaat gaagcaaaaa
     2521 agaaaaaaga aaaaaaaatg acctgtctcc tttcactatc ttcagtacat aaatacatta
     2581 tttaatcaat aagaattaac tgtactaaat cacatattat gctgttctag ttacagccat
     2641 cactctttaa gaaaaatatc cactacacta aataggtact atagtaattt ttagacatgg
     2701 taccattgat atgcatctaa atgtttcact gctgtgttct gttgataaca tatataaata
     2761 ttagataatg ctaatgcttc tgctgctgtc ttttctgtaa tattctcttt catgctgaat
     2821 ttactatgac catttataag caatgcagtt aactacagat agcatttcag gacaaaatag
     2881 atgagtcaaa ccatttattg cttaaaaaat agcttacacc acggttacgc tctaagcagc
     2941 ttttatgcac attgacaaat gaagagtgag cctgggcttg ctaaaggaaa ctgtggaaac
     3001 ttttgtaact tttggtgaaa tgcaacattg tttatggact gttaaagagt atgaggaagt
     3061 cgatgtgtga cgtaagtgct ggcactgatg ctgtccttca tctcctttgg acacgcctgt
     3121 aaatgtgatt ggattgtacg gaagaaaaat tcaaacatct gagatttcaa tgtttcggcc
     3181 ttgtttccat tttgtttgat tgtttgtttg ttttattgta cactctaaaa caacagcatt
     3241 gaacatgggc catgtggttt cattcactct gaaaatcata aggaaatggt gtcttaagac
     3301 cccgcccccc ccaagtagct gcttaccaga tccaagcaaa gaaaatgaat tgtgttcact
     3361 ctgttactat tctggaagaa caactttcat aaagaatcta caggaaaacg ttactgctta
     3421 gaataccctt aaagcccaag taaagggagc atttcagcag cacaagaagg aaattgagaa
     3481 gatgagccct cagcatcctt tagcccatgt tctgcagatc acagttgttt ctgtaacaca
     3541 acagttcctt cattctccac acgcacaaat cgacactatc cacatgctcc ataaatattc
     3601 tgatccctgc agatctcttt tataaatgat ttcattgact gtgctgcatg tgtttccctt
     3661 agcccttcac gggctgataa gtatgcctta aaaatcagga cagccaccat gatcatgtgg
     3721 ctacttacag cacttggaat taaatgactt tctaagtaac cagtgaaata tttatcggat
     3781 agacacccga gatatatgat tgagctcttg gtaaaataga taaattctaa gtgtgtcttt
     3841 aaatgtaaat catatagagg agtcttttct ttgtctatag ttcttccccc tgccctttta
     3901 atattcttgt tctagtcagt cagagagaaa gattcagact ctaagttgtt ctaaaggatg
     3961 aaaagaagaa agatgttaat tttgatgtat aagaacaagt atatttcttg ttgcaatagg
     4021 cagtgtttaa atggactatg taagtcatca gctagcatta agtattccta ataataaaaa
     4081 tttcaaagta taatatcata tactttagaa aaatgaaagg ttttatattc tgatttcttt
     4141 cttttttttt tcagattgac taaaaattct agtcactgat gtttgcaaga ttattgcatt
     4201 ttgtatttca actgcattgg ataccaagca tagaaattag tgaagccatc tttttctttt
     4261 caggttataa aagaaatgta aagctatatc cactagtgtg tgctatctct agttgaagat
     4321 gtgcatatac ccgacaacgt cataaaacaa agaatgttac cttccaaata agttatgaga
     4381 aattattttc ctaggggtgc ttcaaaatca aaatccacat aactgagtgt gtagtatttc
     4441 ttcaagcccc agaagccttg cttcctctag atgctataac aaactgctca gacttgagta
     4501 actatacaaa tttacaatct tggaggtcag aatttcaaag tcagccttaa agggctaaaa
     4561 ccaagatgct aggaacacca ccaccttttg aaggctccag tgaggccttg tttcttccat
     4621 tttctgggga tgtcagtatt tcttcactcc tactaacaac atttcaattt tgcctccctt
     4681 ttttcctgcg gtcacagatc cttctagatt cctgcaagga cacttttttt agggataatt
     4741 acactttttt tagggataat tttagggata attacaggtt aatcttcccc tcttgccatt
     4801 catgcttatg tgccatttgt ccctttgaac agagaagcat tcataggttc ctgggtttat
     4861 gatgtggcta tggggaaaat ctgggaaagg tttcttatcc tgctttattc agtttcccac
     4921 acagccaaag accccagaga gcaaaatgct aattgattaa ttcatgggca aaaagttcta
     4981 agattagtat gtgtgaagga gaattgtcat ttatcattca gattacctcc ccttactttg
     5041 cataaatacc ttttaaaaaa ctcggcatga aaattctcct attccagtaa atcatctggg
     5101 ttatcacatc aaacctttat atgttttaaa tatccttcct ctcatagtta aacatgttac
     5161 gataggaaaa ataaccaacc tgtgaaaact gcaatagcac cgctaaaatg atgctcgtgc
     5221 catattacgt tttcaaaaag catttgcttc tttatcatga gtgagttcgt tctccatgat
     5281 tgtcagatct gcaagtgata actactaatt cactaagaat aataaacaga atatgctctt
     5341 cttaattaaa ggaacaatcc taaaacctga ctcgatttct ttttatattg cagcaaaaaa
     5401 aatatttctt gactgaaatc acagtttttg aactagatta tagacttcta aattgaatca
     5461 cgttttcaac cattcagcct ttccagatta tataatgatg aaacatattg gaaaacaaaa
     5521 acagttgaat gccagttgag tccttaattt tctttccttt cctttttttt tttttttaat
     5581 ctgaaacaaa caagagattt tccaggcaca gtttggcatg gcgaagaaac attaaaagtg
     5641 ggggaaaaaa agggggggaa gaatcaattt atagaaggca attgcaagaa gcatttcgta
     5701 gaagccaagt tccttaaaga tgtttatgtt ccatttaata ctaaagagat aggtgctgcc
     5761 cgggagggtg gagagaggat gactgctttg tgttcttcgg aaagctgacc acatttagtg
     5821 agaactgaac tgctattttt aggactttat tttattttct taactgagac taacttagaa
     5881 cctttaaaaa aaatatggaa aagtatagtt aagaaggaaa atccggctag actagtgggt
     5941 gcctttacag aaatattgat gattttggaa tgttcaatga aaatgcatat ataatagctg
     6001 tggtttaaga atccatatat aaggtaggtt ttcttttcac atataaactc caatactctt
     6061 acttagttct atttgaaaat taagttacta tggggaggaa tttcttttaa gtttgcttgg
     6121 ttgtattaaa attataatta cagttcgaga aaacgttatg aaattcatgt ggtgatagca
     6181 aattaaatat gctcaaaatt taagtctaaa ataaaagccc agaaattgaa aatattgggt
     6241 tgtcttgatc actcagaatg gtggcgcatt cagaccctgt gaatggcatc tcagtgttgc
     6301 cagcctctta atgagctaaa gtttgaataa tttatgactg aactgtaata attctgcact
     6361 gcagtccttt ctccttcctc tcattttctg aaggattcag atatcatgat acttaataca
     6421 tttttccagt tgtgttccaa tttctttaga catatttcat taaatctcaa gaaatgtgtt
     6481 gaggaggaat aaaagcagaa tttggggacc caacaagagc atgtggcttg tctatactgc
     6541 cgctactgtg actcgatttg tctaatgagg tgacaaacta gcaaatgtca ttgtgtttga
     6601 gatgtcagga gatcacgagt agattcctaa cttgggcata gctgtgttct tgatttagct
     6661 tctcgtgata agaattccta ttgcaattat gttttgctga acccgtgttt tggttggttg
     6721 cttggtctta cctttggaac actctttgta ggtaaataaa gcaccattta aaacaacaaa
     6781 aaaaaaaaaa aa
//
