LOCUS       NM_001419594            2262 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus ethanolamine kinase 2 (Etnk2), mRNA.
ACCESSION   NM_001419594
VERSION     NM_001419594.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2262)
  AUTHORS   Flister,M.J., Hoffman,M.J., Reddy,P., Jacob,H.J. and Moreno,C.
  TITLE     Congenic mapping and sequence analysis of the Renin locus
  JOURNAL   Hypertension 61 (4), 850-856 (2013)
   PUBMED   23460292
REFERENCE   2  (bases 1 to 2262)
  AUTHORS   Tian,Y., Jackson,P., Gunter,C., Wang,J., Rock,C.O. and Jackowski,S.
  TITLE     Placental thrombosis and spontaneous fetal death in mice deficient
            in ethanolamine kinase 2
  JOURNAL   J Biol Chem 281 (38), 28438-28449 (2006)
   PUBMED   16861741
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.46394.1,
                                           SRR26643287.28766.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-448               JAXUCZ010000013.1  47363060-47363507
            449-708             JAXUCZ010000013.1  47365041-47365300
            709-831             JAXUCZ010000013.1  47368112-47368234
            832-974             JAXUCZ010000013.1  47372462-47372604
            975-1058            JAXUCZ010000013.1  47373988-47374071
            1059-1204           JAXUCZ010000013.1  47376589-47376734
            1205-1278           JAXUCZ010000013.1  47378039-47378112
            1279-2262           JAXUCZ010000013.1  47380117-47381100
FEATURES             Location/Qualifiers
     source          1..2262
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q13"
     gene            1..2262
                     /gene="Etnk2"
                     /gene_synonym="EKI 2"
                     /note="ethanolamine kinase 2"
                     /db_xref="GeneID:360843"
                     /db_xref="RGD:1305304"
     exon            1..448
                     /gene="Etnk2"
                     /gene_synonym="EKI 2"
                     /inference="alignment:Splign:2.1.0"
     CDS             194..1351
                     /gene="Etnk2"
                     /gene_synonym="EKI 2"
                     /EC_number="2.7.1.82"
                     /note="ethanolamine kinase-like protein"
                     /codon_start=1
                     /product="ethanolamine kinase 2"
                     /protein_id="NP_001406523.1"
                     /db_xref="GeneID:360843"
                     /db_xref="RGD:1305304"
                     /translation="MAVPPSAPVPCSPFYLRRQEACPQCSWSMEEKAVASASCWEPPG
                     PPRAAVPCFAIAVDQDDILPGALRLIRELRPHWKPEQVRTKRFKDGITNKLLACYVEE
                     DMRDCVLVRVYGEWTELLVDRENEIRNFQLLRAHGCAPKLYCTFQNGLCYEYMQGVAL
                     GPEHIREPQLFRLIALEMAKIHTIHANGSLPKPTLWHKMHRYFTLVKDEISPSLSADV
                     PKVEVLEQELAWLKEHLSQLDSPVVFCHNDLLCKNIIYDSDKGHVRFIDYEYAGYNYQ
                     AFDIGNHFNEFAGVNEVDYCRYPAREIQLQWLRYYLEAQKGTAASPREVERLYAQVNK
                     FALASHFFWALWALIQNQYSTINFDFLRYAVIRFNQYFKVKPQVSALEMPK"
     exon            449..708
                     /gene="Etnk2"
                     /gene_synonym="EKI 2"
                     /inference="alignment:Splign:2.1.0"
     exon            709..831
                     /gene="Etnk2"
                     /gene_synonym="EKI 2"
                     /inference="alignment:Splign:2.1.0"
     exon            832..974
                     /gene="Etnk2"
                     /gene_synonym="EKI 2"
                     /inference="alignment:Splign:2.1.0"
     exon            975..1058
                     /gene="Etnk2"
                     /gene_synonym="EKI 2"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1204
                     /gene="Etnk2"
                     /gene_synonym="EKI 2"
                     /inference="alignment:Splign:2.1.0"
     exon            1205..1278
                     /gene="Etnk2"
                     /gene_synonym="EKI 2"
                     /inference="alignment:Splign:2.1.0"
     exon            1279..2262
                     /gene="Etnk2"
                     /gene_synonym="EKI 2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actgtcgcgg cggaccttgg cgatcccggg ccagctgtgc tgcccggctg cgcgccggag
       61 atcggaacag gcagctcgct catgagtcat ggacttcccc tggcccctcc tcgaccactc
      121 ccactccctc tcagggcccc cccgtagggg ctaacgcggg cgcggcggct ccgagggggt
      181 ggggctgctg gggatggctg tgcccccttc agctccagtg ccgtgctcgc ccttttacct
      241 gcggaggcag gaggcttgcc cgcagtgctc atggagcatg gaggagaagg cggtggccag
      301 cgccagttgc tgggagcctc caggcccccc gagggccgcc gtcccgtgct tcgccatcgc
      361 agtggaccag gacgacatcc tccccggtgc tctgcgcctt atccgggagc tgcggccgca
      421 ctggaagccc gaacaagttc ggaccaagcg tttcaaagat ggcatcacca acaagctatt
      481 ggcctgctat gtggaggaag acatgcggga ctgcgtgctg gtccgggtgt acggggagtg
      541 gacagagttg ctggtggacc gggagaatga gatcagaaac ttccaactgc tgcgagcgca
      601 cggctgcgcc cccaaactct actgtacctt tcagaacggg ctatgctacg agtacatgca
      661 gggtgtggcc ctgggaccag agcatatccg agagccccag ctcttcaggt taatcgccct
      721 agaaatggca aagattcaca ccatccacgc caatggcagt ctgcctaagc ccactctctg
      781 gcataagatg caccgctatt tcacgctggt caaggatgag atcagtccca gcctttctgc
      841 agatgtcccc aaggtagagg tgttggaaca ggagctggcc tggctgaagg aacacctgtc
      901 ccagttggat tcccccgtgg tgttctgtca caatgacctg ctctgcaaga atatcatcta
      961 tgacagtgac aaaggccacg tgcgcttcat cgactatgaa tacgcagggt acaactacca
     1021 ggctttcgac attggcaacc atttcaatga gtttgcaggt gtgaatgagg ttgattactg
     1081 caggtatcca gctcgggaga tccagctaca gtggctacgc tattatctgg aggcacagaa
     1141 ggggacagct gcgtccccca gggaggtgga gcggctttac gcacaagtca acaaatttgc
     1201 tctggcatcc catttcttct gggcactctg ggcactcata cagaaccagt attccaccat
     1261 caactttgac ttcctcaggt atgcagtgat ccgattcaac cagtacttta aggtgaagcc
     1321 tcaggtgtca gccttggaga tgccaaagtg accagcctcc tgtttctcca tgccctcttg
     1381 ctgccagaat tgctccccgg ggtacccttc tgccttggag ttggcacact gggacaaggt
     1441 gagcatcttt ggagaaggcc cccccacagt ggatgccaac aaagacctca ctttcctgtt
     1501 tggaggggct gccgagcccc agcgttgcgg ggggatcctc ttcaccctgc caggcttgga
     1561 gaggaagtgc ctgcagatgg ctggggcctg cactgccacc ctgtcgtgag agcacagtgt
     1621 agccagccca ggcttgctag agcttgggct gcctcagtcc gtccttgacc cttcctggca
     1681 ggggagggga agggcttgtt tctacctctg gtgccagcct ccagctgagc catgtatgcc
     1741 ccagtgagag gtgctgagct ccaagccagc aggaagccaa ttcagctgtc atcttggggg
     1801 gagaggtccc agctgcacct gacagttcct ccagcagctg ccttatctga ggctgccaac
     1861 ttctccaagc cagatgccat ccagccaccc cttccctagg tcccctcctc gtgttcctgc
     1921 taggtccctg cagaggagag ggacagagac ctgggagtag gcctggcctt gagtcatggg
     1981 gcaggtacca gagccagcag catcctccac ctctccccct tctattctga acttaacttc
     2041 tggtcttccc attggggaat gaatggtgga aggcaagggg gcaaggccta ggtgccgtga
     2101 ggccagcaca gctgcctggg catgtccaga tgctgacggt gttgtcagtt cagtgtccac
     2161 gtcccagtcc ttacagttcc tgagggggtc cggtataggc ctccactgtg attcatttgt
     2221 agattatcat ggttttctgc attaaaatgt ttgtttcttg ga
//
