LOCUS       NP_001012490             480 aa            linear   ROD 23-MAR-2023
DEFINITION  splicing factor ESS-2 homolog [Rattus norvegicus].
ACCESSION   NP_001012490 XP_341014
VERSION     NP_001012490.1
DBSOURCE    REFSEQ: accession NM_001012472.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 480)
  AUTHORS   Jurica MS, Licklider LJ, Gygi SR, Grigorieff N and Moore MJ.
  TITLE     Purification and characterization of native spliceosomes suitable
            for three-dimensional structural analysis
  JOURNAL   RNA 8 (4), 426-439 (2002)
   PUBMED   11991638
REFERENCE   2  (residues 1 to 480)
  AUTHORS   Lindsay EA, Harvey EL, Scambler PJ and Baldini A.
  TITLE     ES2, a gene deleted in DiGeorge syndrome, encodes a nuclear protein
            and is expressed during early mouse development, where it shares an
            expression domain with a Goosecoid-like gene
  JOURNAL   Hum Mol Genet 7 (4), 629-635 (1998)
   PUBMED   9499415
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC089898.1.
            
            On Apr 20, 2005 this sequence version replaced XP_341014.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089898.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q23"
     Protein         1..480
                     /product="splicing factor ESS-2 homolog"
                     /note="DiGeorge syndrome critical region gene 14 homolog;
                     DiGeorge syndrome critical region protein 14; protein
                     DGCR14"
                     /calculated_mol_wt=52527
     Region          37..405
                     /region_name="Es2"
                     /note="Nuclear protein Es2; pfam09751"
                     /db_xref="CDD:430802"
     CDS             1..480
                     /gene="Ess2"
                     /gene_synonym="Dgcr14"
                     /coded_by="NM_001012472.1:4..1446"
                     /db_xref="GeneID:360741"
                     /db_xref="RGD:1308218"
ORIGIN      
        1 mgtpgvsaga lflssasapp rkraageage agvakskqrv ldeeeyiegl qtviqrdffp
       61 dveklqaqke yleaeengdl ermrqiaikf gsalgkisre ppppyvtpat fetpevhpgs
      121 gvlgskprpq grdpedagea geeeekeplp sldvflsryt sednasfqei mevakeksha
      181 rhawlyqaee efekrqkdnl elpsaehqai essqagvetw kykaknslmy ypegvpdeeq
      241 lfkkprqivh kntrflrdpf sqalsrsqlq qaaalnaqhk qgkvgpdgke lipqesprvg
      301 gfgfvatpsp apgmnesplm twgeventpl rvegsespyv drtpgptfki lepgrrerlg
      361 lkmaneaaak nrakkqealr rvtenlaslt pkglspamsp alqrlvsrta skytdralra
      421 sytpsparst hlktpaggpq tptstpapgs atrtpltqdp asitdnllql parrkasdff
//
