LOCUS       NM_001191812            4522 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus espin-like (Espnl), mRNA.
ACCESSION   NM_001191812 XM_237393
VERSION     NM_001191812.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4522)
  AUTHORS   Ebrahim,S., Avenarius,M.R., Grati,M., Krey,J.F., Windsor,A.M.,
            Sousa,A.D., Ballesteros,A., Cui,R., Millis,B.A., Salles,F.T.,
            Baird,M.A., Davidson,M.W., Jones,S.M., Choi,D., Dong,L.,
            Raval,M.H., Yengo,C.M., Barr-Gillespie,P.G. and Kachar,B.
  TITLE     Stereocilia-staircase spacing is influenced by myosin III motors
            and their cargos espin-1 and espin-like
  JOURNAL   Nat Commun 7, 10833 (2016)
   PUBMED   26926603
  REMARK    Erratum:[Nat Commun. 2017 Aug 14;8:16133. PMID: 28805204]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4522)
  AUTHORS   Lelli,A., Michel,V., Boutet de Monvel,J., Cortese,M.,
            Bosch-Grau,M., Aghaie,A., Perfettini,I., Dupont,T., Avan,P.,
            El-Amraoui,A. and Petit,C.
  TITLE     Class III myosins shape the auditory hair bundles by limiting
            microvilli and stereocilia growth
  JOURNAL   J Cell Biol 212 (2), 231-244 (2016)
   PUBMED   26754646
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Oct 22, 2022 this sequence version replaced NM_001191812.1.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN17050747,
                              SAMN17050753 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-305               JAXUCZ010000009.1  99359578-99359882
            306-496             JAXUCZ010000009.1  99361015-99361205
            497-683             JAXUCZ010000009.1  99362565-99362751
            684-866             JAXUCZ010000009.1  99364709-99364891
            867-998             JAXUCZ010000009.1  99371740-99371871
            999-1113            JAXUCZ010000009.1  99377386-99377500
            1114-1196           JAXUCZ010000009.1  99378764-99378846
            1197-1391           JAXUCZ010000009.1  99379449-99379643
            1392-4522           JAXUCZ010000009.1  99381212-99384342
FEATURES             Location/Qualifiers
     source          1..4522
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q36"
     gene            1..4522
                     /gene="Espnl"
                     /gene_synonym="RGD1562432"
                     /note="espin-like"
                     /db_xref="GeneID:301606"
                     /db_xref="RGD:1562432"
     exon            1..305
                     /gene="Espnl"
                     /gene_synonym="RGD1562432"
                     /inference="alignment:Splign:2.1.0"
     CDS             12..3011
                     /gene="Espnl"
                     /gene_synonym="RGD1562432"
                     /codon_start=1
                     /product="espin-like protein"
                     /protein_id="NP_001178741.1"
                     /db_xref="GeneID:301606"
                     /db_xref="RGD:1562432"
                     /translation="MEAQQALVASKDGDLATLERLFEAGGLRPDITDDLGAGLVHHAT
                     RAGHLDCVKFLVQTAKLPSDQQAHNGATPVHDAAAMGNLAELCWLIRDGGCGLQDQDA
                     SGVSPLHLAARFGHPALVEWLLREGHAATLETLEGALPLHHAAVSGDLTCLKLLTAAH
                     SSGVNQRTCSGASPLYLACQEGHLHLAQFLVKDCGADVRLRALDGMSSLHAAAARGHY
                     SLVVWLVTFTDIGLTARDNEGATALHFAARGGHTPILDRLLLMGAPIMRDSWGGTPLH
                     DAAENGHMECCQTLLSHHVDPFLRDEDGYTAIDLAEYHGHQDCAQFLREMSRPVPVLM
                     TPPPPPFPPPPLLAAGLPLEEERRGDSGLRSPSSAWPAQPVPREPMACTAPLSVTSSA
                     ALQGAEVEPLDSHDGLTTLQLDRLPSGDLDMLVPTQDERGRPIPEWKRQVMVRKLQAR
                     LGADHPPEDQDQSQRQDSGPTPAEQATWRYSQTHQAILGPFGELLTEDDLVYLEKQIN
                     DLQLRRRCQEYESELGRLAAQLQALLPEPLVSITVNSHFLPRAPGLDDEEGPALAPEL
                     EASEEPGKAEPRGQPLPFWCSHIGRLVRSMSLLLKGMNGLAQGEEKPPASVPQDPSKE
                     TMAGPSRSEAQREIQECGVSVRTLRGNFEFAPDLPCASNSGPCELGARPGQCLRGCWS
                     APPQPRGEPMGREPRPGDTEEASDSGISCEEAPSEAGAGPGLDLANLRKERIVMLFLG
                     HWKKSAYTPALRTAACRTLEAQRARSRGPEAASSPRPLSPQPSDSPRLGHLWQQRGII
                     THLLGTWKAIMAHVPARQLRRLSRRARGPLSPEQFLPHVDGAPVPYNSLSLDLFMLGY
                     FQLLECDLPAEERKMRHLLCFEVFEHLGAHGWEAVRAFHKAVTDEVAAGRRAWTDGFE
                     DIKARFFGSSQGPPWDVEPGRKLGLTPLGSLPHAALPGSGPEPASPRLGSNSQQGSFN
                     SGDICGYIDRSFAFWKEKEAEMFNFGE"
     exon            306..496
                     /gene="Espnl"
                     /gene_synonym="RGD1562432"
                     /inference="alignment:Splign:2.1.0"
     exon            497..683
                     /gene="Espnl"
                     /gene_synonym="RGD1562432"
                     /inference="alignment:Splign:2.1.0"
     exon            684..866
                     /gene="Espnl"
                     /gene_synonym="RGD1562432"
                     /inference="alignment:Splign:2.1.0"
     exon            867..998
                     /gene="Espnl"
                     /gene_synonym="RGD1562432"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1113
                     /gene="Espnl"
                     /gene_synonym="RGD1562432"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1196
                     /gene="Espnl"
                     /gene_synonym="RGD1562432"
                     /inference="alignment:Splign:2.1.0"
     exon            1197..1391
                     /gene="Espnl"
                     /gene_synonym="RGD1562432"
                     /inference="alignment:Splign:2.1.0"
     exon            1392..4522
                     /gene="Espnl"
                     /gene_synonym="RGD1562432"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtcagtcag gatggaggca cagcaggcac tggtggcctc caaggacggg gatttggcca
       61 ccttggagcg gctgtttgag gctggtggcc tgagaccaga catcactgat gatttggggg
      121 ctggcctggt gcatcatgcc acccgggctg gtcacctgga ctgtgtcaag ttcctggtac
      181 agacagccaa gctgccgagt gaccagcagg cacacaacgg ggcgacacca gtgcacgatg
      241 cagcagccat gggcaacctg gcagagctgt gctggctcat ccgggacggg ggctgcgggc
      301 tgcaggacca agatgcctca ggtgtctccc cactgcacct ggctgcccgg tttggacacc
      361 cggcactggt ggagtggttg ctgcgtgagg gccatgcagc cacactggag acgctggaag
      421 gggccttgcc gctgcaccac gctgctgtga gtggtgacct gacctgtctg aaactcctga
      481 cagcagccca cagcagtggt gtgaaccagc ggacatgcag tggtgcctct ccactctacc
      541 tggcctgcca agagggccac ctgcatctgg cacagttcct ggtgaaagac tgtggggctg
      601 acgtgcgcct acgagccctg gatggcatga gttcattaca tgctgcggcg gcccgtggcc
      661 actactctct agttgtctgg ctggtcacat tcacagacat cggcctgaca gcacgggata
      721 atgaaggagc cactgccctg cactttgcag ctcgcggggg ccacacgccc attcttgacc
      781 gcctcctgct catgggtgcc cccatcatga gagattcctg gggagggact cccctgcatg
      841 acgcagccga gaatggacac atggagtgct gccagacctt gctctcccac catgtagacc
      901 ccttcctgag ggatgaagat gggtatacgg cgatagacct agcagagtat catggacacc
      961 aggattgtgc ccagttcctg cgggaaatgt ctcggccggt gccagttctg atgacacccc
     1021 cacccccacc attcccacct cctccactgc tggctgcagg actccccctg gaagaagaaa
     1081 gaagagggga ctcgggactc aggagcccct cttcagcctg gcctgctcag cctgtcccaa
     1141 gggaaccaat ggcctgtaca gcccctctga gtgtcacctc ctcagctgcc cttcaggggg
     1201 ctgaggtgga acccctagac tcccatgatg gcctgaccac tctgcagctg gatcggttgc
     1261 cttcaggaga ccttgacatg ctggtgccca cccaggatga gcgaggccgg cccatccctg
     1321 agtggaagcg gcaggtgatg gtgcggaagc tgcaggctcg cctgggtgca gatcatcctc
     1381 cagaagatca ggaccagagt caaaggcagg actcaggccc cacccctgca gaacaggcaa
     1441 cttggaggta ttcgcagact caccaggcca tcctgggccc cttcggggag ctgctgacag
     1501 aagatgacct tgtctacctg gagaaacaga tcaacgacct gcagctccgg cgccgatgcc
     1561 aggagtatga gagcgagctg ggccggctgg cagctcagct gcaggccctc ctgcccgagc
     1621 ccctggtcag catcaccgtc aatagccact ttctgccccg ggctcccggc ctggatgacg
     1681 aggaaggtcc agccctggcg cctgaactcg aagcctccga ggagcccggg aaggcggagc
     1741 ccagagggca gccactgccc ttctggtgca gccacatcgg tcgcctggtg cgcagcatgt
     1801 ccctgctgct gaagggcatg aatgggctgg cacagggcga ggagaagccg cccgcctcgg
     1861 tccctcagga cccaagcaag gagaccatgg ccggcccctc tcggagcgag gcccagcgcg
     1921 agatccagga gtgcggagtg tcagttcgaa ctttgcgggg gaatttcgag tttgccccag
     1981 atctgccctg cgcctcgaac tcgggtccct gtgagctggg ggcgcggccg ggccagtgtc
     2041 tgagaggctg ctggtcggcg ccgccacagc cccgaggtga gccgatggga agggagcccc
     2101 ggccaggcga cacggaggag gccagcgact cgggcatcag ttgtgaggag gccccgtcag
     2161 aggccggcgc cggtccggga ctggacctgg ccaacctgcg caaggaacgc atcgtcatgc
     2221 ttttcctcgg ccattggaag aagtcggcct acacaccggc gctcaggacc gccgcctgca
     2281 ggaccctgga ggctcaacgt gcacgatcca ggggccccga ggccgcgagt agcccccggc
     2341 cgctctcccc gcagcccagc gacagtccca ggctcggcca cctgtggcag cagcgtggca
     2401 tcatcaccca cctgctgggc acctggaaag ccatcatggc gcacgtgccg gcccggcagc
     2461 tgcggaggct gagccgcagg gcgcgcgggc ccctgtcccc cgagcagttc ttgcctcacg
     2521 tggacggggc acccgtgccc tacaacagcc tctcgctgga cctcttcatg ctcggctact
     2581 ttcagctcct ggagtgcgac ctgccagccg aggagcgcaa gatgcggcac ttgctatgct
     2641 ttgaggtttt cgagcaccta ggcgcacacg gctgggaggc cgtgcgagcc ttccataaag
     2701 cagtgaccga cgaggtggcc gcgggccgcc gtgcctggac cgacggtttt gaggacatca
     2761 aagcccgctt tttcggctcc agccagggtc ccccctggga cgtggaaccg ggtcgcaagc
     2821 tgggcctgac acctctcggt tccttgcccc atgctgccct ccctggcagc ggccccgaac
     2881 ctgcatcccc gaggctgggg tctaattctc agcagggcag cttcaacagc ggggacatct
     2941 gtggctacat cgaccgcagc ttcgccttct ggaaggaaaa agaagctgag atgtttaatt
     3001 ttggagaatg actgttcacc tggtgggata ggactctggg ggaagtttgg ggttcctttg
     3061 ttcattcttt atgctccctg gggttcaggt gaagtgggca cagtgatggt tgactcctgt
     3121 ttgtcttcgt ggagatcgga agccatgtcc cgcagaagtc tcttaagcca tggtgtccat
     3181 ctcttctgag cagtgattgg ggtcaaatcc tcacttggga gcacagcccc caggccctca
     3241 agtggtcata tgggtctgag ggtcctgcag ccaaggagct ggtgtcctag caccagggcc
     3301 ctcttgccag tcatgtttcc agcagtcacg tggaagtctg catctttggt ttcaatggct
     3361 cgggtggtct cagctccacc accaccctct ctatacctcc ctttgggcct cagccctggg
     3421 cttgcctcta gtgtttgttt gtttgtttgt ttgtttgttt gtttgtttgt ttgtttgttt
     3481 ctggcaacct cctatctcta aaaccagagg gagtgtgtct agcgtgaaca atctccctga
     3541 cagaagggct tctgtggagg agaccctaaa gccccagcag acaagtggtc ctgccctgat
     3601 tttcctgctt ggcagtcata actgctattg tcattctagc aacatctctc ctctggcact
     3661 gcctggcccc tgggggaagg ctaggagggc cctaagagca gggacaccaa gaatatccat
     3721 ccacgggggg gtgaggagtt cttccaatac aaaggttggt accttctgaa gggaaactgg
     3781 ccttctgtag ctgggaacag cttacagcaa aggaagaaca tagcaggggt ggtcatgtgg
     3841 ccttttgggt ttcaccttcc catgccttgg agattccagg taccatagag aaccacagca
     3901 actaggtgct agagagggag ccctccaggt ggctgactgt aagatggggc tcgattacag
     3961 cttctggtga caggcagaag gatgagtcac cacccacctc atggggccca ggagaactgg
     4021 cctggaaccc ccggaggact ttggggtagt gaccttttga ggagactaca attggtatgg
     4081 aacaggggtc ggcagtccag tctcttgggg cagtcattca caatggggcc cggccatgtc
     4141 caagagtctc ctacagtgtc cccgaatcac cactgggggg agcaggaagc cctaaccttg
     4201 ggctcttgga tggtagtaga aaggctgttg gctggatgga gcagagcctc acagacaagt
     4261 ctaggaaggg gtcccatgga tagggacctc cagggagata aagttggcat ggggcatgga
     4321 ttttggtgct ggaaaagcca caaaaggcag tggtataggt cctgactcca agttgtctcc
     4381 ctcccttgcc caccctggga cctgctctga ggtgacaggg tgaatcctcc tacttggccc
     4441 ttggcttcct ctgtttttag agtctcttca gaagctgacg ctggctgtgt gtttgctaaa
     4501 taaaattgct gtccctggcc gg
//
