LOCUS       NP_001094241             842 aa            linear   ROD 26-OCT-2024
DEFINITION  ESF1 homolog [Rattus norvegicus].
ACCESSION   NP_001094241 XP_001081317 XP_345441
VERSION     NP_001094241.1
DBSOURCE    REFSEQ: accession NM_001100771.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 842)
  AUTHORS   Pieragostino,D., Agnifili,L., Fasanella,V., D'Aguanno,S.,
            Mastropasqua,R., Di Ilio,C., Sacchetta,P., Urbani,A. and Del
            Boccio,P.
  TITLE     Shotgun proteomics reveals specific modulated protein patterns in
            tears of patients with primary open angle glaucoma naive to therapy
  JOURNAL   Mol Biosyst 9 (6), 1108-1116 (2013)
   PUBMED   23580065
REFERENCE   2  (residues 1 to 842)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (residues 1 to 842)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (residues 1 to 842)
  AUTHORS   Oda,T., Fukuda,A., Hagiwara,H., Masuho,Y., Muramatsu,M.A.,
            Hisatake,K. and Yamashita,T.
  TITLE     ABT1-associated protein (ABTAP), a novel nuclear protein conserved
            from yeast to mammals, represses transcriptional activation by ABT1
  JOURNAL   J Cell Biochem 93 (4), 788-806 (2004)
   PUBMED   15660422
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On or before Nov 22, 2008 this sequence version replaced
            XP_001081317.1, XP_345441.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.1559776.1,
                                           SRR26643289.11030.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..842
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q36-q41"
     Protein         1..842
                     /product="ESF1 homolog"
                     /note="ABT1-associated protein"
                     /calculated_mol_wt=97404
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylserine.
                     /evidence=ECO:0000250|UniProtKB:Q9H501; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Region          54..317
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            75
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            77
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            79
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            82
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            135
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9H501; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            155
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9H501; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            180
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            198
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9H501; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            288
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9H501; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            290
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9H501; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Region          293..827
                     /region_name="COG5638"
                     /note="Uncharacterized conserved protein [Function
                     unknown]"
                     /db_xref="CDD:227925"
     Site            303
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            304
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            305
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Region          534..568
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            605
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9H501; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Region          631..657
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            648
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            654
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Region          674..693
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            686
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Site            726
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9H501; propagated from
                     UniProtKB/Swiss-Prot (Q76MT4.1)"
     Region          785..816
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q76MT4.1)"
     CDS             1..842
                     /gene="Esf1"
                     /gene_synonym="RGD1306067"
                     /coded_by="NM_001100771.2:129..2657"
                     /db_xref="GeneID:366203"
                     /db_xref="RGD:1306067"
ORIGIN      
        1 msskqeimdd qrfrrvskdp rfwempekdr kvkidkrfra mfhdkkfkln yavdkrgrpi
       61 shsttedlkr fydlsdsdsd lsdeeskvld ekrvkekkkq tkketksktp ieekkketkk
      121 tdqkdsinkn dlnnseriqk mknshkspki dsevspkdse eslqsrkkkr dttdlsveas
      181 pkgklrtkdp stsamvksst vsgskakrek qavimakdna grmlheeape edsdsaselg
      241 rdeesegeit sddrasaddd enedeeeeed geeeeeeeee edesddesds gpdlargkgn
      301 vetssededd ladlfpeepg fehawreldk dapradeitr rlavcnmdwd rlkakdllal
      361 fnsfkpkggv vfsvkiypse fgkqrmkeeq iqgpvellsi pedapekdwa sreklrdyqf
      421 krlkyyyavv ecdspetask iyedcdglef esscsfidlr fipdditfdd epkdaasevd
      481 ltaykpkyft saamgtstve itwdetdher ittlnrkfkk delldmdfea ylasssedee
      541 eveeapeged gvsiedgktk ksqkddeeqi akyrqllqvi qekekkgken dmemeikwvp
      601 glkesaeemv knklegkdkl tpweqflekk kekkrlkkkq kalaeeased eipsdvdlnd
      661 pyfaeevkki gikkksmksa kdgatseeet elekqkaema llvmdeeeds kkhfnydkiv
      721 ehqnlskkkk kqlmkkkell eddfevnvsd arfqamytsh lfnldpsdpn fkktkameki
      781 leekarhreq keerliqave raqqdtgkpa qkqpmdpals mliksvknkt eqfqarkkqr
      841 ik
//
