LOCUS       NM_001008317            1411 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus endoplasmic reticulum protein 44 (Erp44), mRNA.
ACCESSION   NM_001008317 XM_216396
VERSION     NM_001008317.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1411)
  AUTHORS   Holbrook,L.M., Watkins,N.A., Simmonds,A.D., Jones,C.I.,
            Ouwehand,W.H. and Gibbins,J.M.
  TITLE     Platelets release novel thiol isomerase enzymes which are recruited
            to the cell surface following activation
  JOURNAL   Br J Haematol 148 (4), 627-637 (2010)
   PUBMED   19995400
REFERENCE   2  (bases 1 to 1411)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   3  (bases 1 to 1411)
  AUTHORS   Breuza,L., Halbeisen,R., Jeno,P., Otte,S., Barlowe,C., Hong,W. and
            Hauri,H.P.
  TITLE     Proteomics of endoplasmic reticulum-Golgi intermediate compartment
            (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies
            ERGIC-32, a new cycling protein that interacts with human Erv46
  JOURNAL   J Biol Chem 279 (45), 47242-47253 (2004)
   PUBMED   15308636
REFERENCE   4  (bases 1 to 1411)
  AUTHORS   Anelli,T., Alessio,M., Mezghrani,A., Simmen,T., Talamo,F., Bachi,A.
            and Sitia,R.
  TITLE     ERp44, a novel endoplasmic reticulum folding assistant of the
            thioredoxin family
  JOURNAL   EMBO J 21 (4), 835-844 (2002)
   PUBMED   11847130
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001008317.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY158662.1, FQ211910.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676787 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-130               JAXUCZ010000005.1  67406078-67406207   c
            131-203             JAXUCZ010000005.1  67369042-67369114   c
            204-243             JAXUCZ010000005.1  67366758-67366797   c
            244-359             JAXUCZ010000005.1  67362227-67362342   c
            360-544             JAXUCZ010000005.1  67345848-67346032   c
            545-660             JAXUCZ010000005.1  67344585-67344700   c
            661-718             JAXUCZ010000005.1  67338835-67338892   c
            719-835             JAXUCZ010000005.1  67328911-67329027   c
            836-947             JAXUCZ010000005.1  67325759-67325870   c
            948-1089            JAXUCZ010000005.1  67324738-67324879   c
            1090-1192           JAXUCZ010000005.1  67315499-67315601   c
            1193-1411           JAXUCZ010000005.1  67313245-67313463   c
FEATURES             Location/Qualifiers
     source          1..1411
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q22"
     gene            1..1411
                     /gene="Erp44"
                     /gene_synonym="BWK4; Txndc4"
                     /note="endoplasmic reticulum protein 44"
                     /db_xref="GeneID:298066"
                     /db_xref="RGD:1309176"
     exon            1..130
                     /gene="Erp44"
                     /gene_synonym="BWK4; Txndc4"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..1294
                     /gene="Erp44"
                     /gene_synonym="BWK4; Txndc4"
                     /note="thioredoxin domain containing 4 (endoplasmic
                     reticulum); endoplasmic reticulum resident protein 44"
                     /codon_start=1
                     /product="endoplasmic reticulum resident protein 44
                     precursor"
                     /protein_id="NP_001008318.1"
                     /db_xref="GeneID:298066"
                     /db_xref="RGD:1309176"
                     /translation="MNPTVFLSLPDLRCSLLLLVTSIFAPITAEIASLDSENIDEILN
                     NADVALVNFYADWCRFSQMLHPIFEEASDVIKEEYPDKNQVVFARVDCDQHSDIAQRY
                     RISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSNPVHEIQSLDEVTNLDRSK
                     RNIIGYFEQKDSDNYRVFERVASILHDDCAFLSAFGDLSKPERYSGDNLIYKPPGRSV
                     PDMVYLGSMTNFDVTFNWIQDKCVPLVREITFENGEELTEEGLPFLILFHMKEDTESL
                     EIFQNEVARQLISEKGTINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGD
                     FKDVLIPGKLKQFVFDLHSGKLHREFHHGPDPTDTAPGEQDQDVASSPPESSFQKLAP
                     SEYRYTLLRDRDEL"
     exon            131..203
                     /gene="Erp44"
                     /gene_synonym="BWK4; Txndc4"
                     /inference="alignment:Splign:2.1.0"
     exon            204..243
                     /gene="Erp44"
                     /gene_synonym="BWK4; Txndc4"
                     /inference="alignment:Splign:2.1.0"
     exon            244..359
                     /gene="Erp44"
                     /gene_synonym="BWK4; Txndc4"
                     /inference="alignment:Splign:2.1.0"
     exon            360..544
                     /gene="Erp44"
                     /gene_synonym="BWK4; Txndc4"
                     /inference="alignment:Splign:2.1.0"
     exon            545..660
                     /gene="Erp44"
                     /gene_synonym="BWK4; Txndc4"
                     /inference="alignment:Splign:2.1.0"
     exon            661..718
                     /gene="Erp44"
                     /gene_synonym="BWK4; Txndc4"
                     /inference="alignment:Splign:2.1.0"
     exon            719..835
                     /gene="Erp44"
                     /gene_synonym="BWK4; Txndc4"
                     /inference="alignment:Splign:2.1.0"
     exon            836..947
                     /gene="Erp44"
                     /gene_synonym="BWK4; Txndc4"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1089
                     /gene="Erp44"
                     /gene_synonym="BWK4; Txndc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1090..1192
                     /gene="Erp44"
                     /gene_synonym="BWK4; Txndc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1193..1411
                     /gene="Erp44"
                     /gene_synonym="BWK4; Txndc4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcccagccc ttttctagcc cggtccagtc ccagcagcca cctcctgacc ccgccgtcga
       61 ccccatcgtt accatgaatc ctaccgtctt cctgtcttta ccagacctca gatgctcctt
      121 gctactcctg gtaacttcga tttttgcacc tataacagct gaaatagcaa gtcttgattc
      181 agagaatata gatgaaattt taaataatgc tgatgttgct ttagtaaatt tttatgctga
      241 ctggtgtcgt ttcagccaga tgttgcatcc aatttttgag gaagcatctg atgtcattaa
      301 ggaagaatat ccagataaaa atcaagtagt gtttgccaga gttgattgtg atcagcactc
      361 tgatatagcc cagaggtaca ggataagcaa atacccaacc ctgaaattat ttcgtaatgg
      421 aatgatgatg aagagagaat acaggggcca gcgatcagtg aaagcgcttg cagactacat
      481 caggcaacag aaaagtaacc ccgtccacga gattcagagt ctagatgaag tcaccaatct
      541 tgatcgcagt aagagaaata tcattggata ctttgagcag aaggattcag ataattacag
      601 agtttttgaa agagtagcaa gtattttgca tgatgactgt gccttccttt ctgcttttgg
      661 agatctttca aaaccagaaa ggtacagtgg agacaattta atctacaaac caccggggcg
      721 ttctgtgcca gacatggtgt acttgggatc tatgacaaat tttgatgtaa ctttcaactg
      781 gattcaagat aaatgtgtcc ctcttgtccg agaaataaca tttgaaaatg gagaggaatt
      841 gacagaagaa ggactgcctt ttctcattct cttccacatg aaggaggata cagaaagttt
      901 agaaatattc cagaatgaag tagcccggca gttgataagt gaaaaaggta caataaattt
      961 cttacatgca gattgtgaca aatttagaca tcctcttctc catatccaga agactccagc
     1021 agattgccct gtcatagcca ttgacagctt taggcatatg tatgtctttg gagactttaa
     1081 ggatgtatta attcctggaa aactcaagca gtttgtattt gacctacatt ctggaaaact
     1141 acacagagaa ttccatcatg gacctgaccc aactgataca gccccaggag agcaagacca
     1201 ggatgtagcg agcagtcctc ctgagagctc cttccagaag ctggcgccca gcgaatatag
     1261 gtatacttta ttgagggatc gagatgagct gtaaaaactc aagaacacca cagcctttca
     1321 acagcagcac aggctgacgt ggtggaaata gtaaacctat attttcataa ttctatgtgt
     1381 atttttattt tgaataaact gaaagaagtt t
//
