LOCUS       NM_001008311            1805 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus ermin (Ermn), mRNA.
ACCESSION   NM_001008311 XM_238268
VERSION     NM_001008311.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1805)
  AUTHORS   Ruskamo,S., Chukhlieb,M., Vahokoski,J., Bhargav,S.P., Liang,F.,
            Kursula,I. and Kursula,P.
  TITLE     Juxtanodin is an intrinsically disordered F-actin-binding protein
  JOURNAL   Sci Rep 2, 899 (2012)
   PUBMED   23198089
  REMARK    GeneRIF: Data indicate that juxtanodin is non-globular and
            monomeric in solution.
REFERENCE   2  (bases 1 to 1805)
  AUTHORS   Wang,T., Jia,L., Yang,G., Ji,S., Yao,L. and Zhang,B.
  TITLE     Identification of Juxtanodin promoter and its transcriptional
            regulation during the ATRA-induced differentiation of C6 cells
  JOURNAL   Mol Cell Biochem 350 (1-2), 177-183 (2011)
   PUBMED   21221725
  REMARK    GeneRIF: Nkx2.2 is one of the essential transcription factors
            delivering the specificity of JN promoter in oligodendrocytes.
REFERENCE   3  (bases 1 to 1805)
  AUTHORS   Wang,T., Jia,L., Lv,B., Liu,B., Wang,W., Wang,F., Yang,G., Bu,X.,
            Yao,L. and Zhang,B.
  TITLE     Human Ermin (hErmin), a new oligodendrocyte-specific cytoskeletal
            protein related to epileptic seizure
  JOURNAL   Brain Res 1367, 77-84 (2011)
   PUBMED   20934411
REFERENCE   4  (bases 1 to 1805)
  AUTHORS   Meng,J., Xia,W., Tang,J., Tang,B.L. and Liang,F.
  TITLE     Dephosphorylation-dependent inhibitory activity of juxtanodin on
            filamentous actin disassembly
  JOURNAL   J Biol Chem 285 (37), 28838-28849 (2010)
   PUBMED   20610382
  REMARK    GeneRIF: Specific phosphorylation of JN might serve as an important
            mechanism regulating JN functions.
REFERENCE   5  (bases 1 to 1805)
  AUTHORS   Tang,J., Tang,J., Ling,E.A., Wu,Y. and Liang,F.
  TITLE     Juxtanodin in the rat olfactory epithelium: specific expression in
            sustentacular cells and preferential subcellular positioning at the
            apical junctional belt
  JOURNAL   Neuroscience 161 (1), 249-258 (2009)
   PUBMED   19332107
  REMARK    GeneRIF: These results identify JN as a marker protein for OE
            sustentacular cells, and support the glia-like nature of OE
            sustentacular cells.
REFERENCE   6  (bases 1 to 1805)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   7  (bases 1 to 1805)
  AUTHORS   Brockschnieder,D., Sabanay,H., Riethmacher,D. and Peles,E.
  TITLE     Ermin, a myelinating oligodendrocyte-specific protein that
            regulates cell morphology
  JOURNAL   J Neurosci 26 (3), 757-762 (2006)
   PUBMED   16421295
REFERENCE   8  (bases 1 to 1805)
  AUTHORS   Zhang,B., Cao,Q., Guo,A., Chu,H., Chan,Y.G., Buschdorf,J.P.,
            Low,B.C., Ling,E.A. and Liang,F.
  TITLE     Juxtanodin: an oligodendroglial protein that promotes cellular
            arborization and 2',3'-cyclic nucleotide-3'-phosphodiesterase
            trafficking
  JOURNAL   Proc Natl Acad Sci U S A 102 (32), 11527-11532 (2005)
   PUBMED   16051705
  REMARK    GeneRIF: Juxtanodin is an oligodendroglial protein that promotes
            cellular arborization and 2',3'-cyclic
            nucleotide-3'-phosphodiesterase trafficking.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC086596.1.
            
            On Jun 3, 2007 this sequence version replaced NM_001008311.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086596.1, DQ119821.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760396
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1805
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q21"
     gene            1..1805
                     /gene="Ermn"
                     /gene_synonym="juxtanodin; RGD1308367"
                     /note="ermin"
                     /db_xref="GeneID:295619"
                     /db_xref="RGD:1308367"
     exon            1..390
                     /gene="Ermn"
                     /gene_synonym="juxtanodin; RGD1308367"
                     /inference="alignment:Splign:2.1.0"
     CDS             153..1001
                     /gene="Ermn"
                     /gene_synonym="juxtanodin; RGD1308367"
                     /note="JN; ermin, ERM-like protein"
                     /codon_start=1
                     /product="ermin"
                     /protein_id="NP_001008312.1"
                     /db_xref="GeneID:295619"
                     /db_xref="RGD:1308367"
                     /translation="MTDTPVTLSGSECNGDRPPENGQQPSSQTRKTTDADETQTYYGV
                     EPSLQHLPAKENQEESGNSKGNVLPRGSEDEKILNENTEENLFVVHQAIQDLSLQETS
                     AEDTVFQEGHPWKKIPLNSHNLDMSRQKERIVHQHLEQREDESAAHQATEIEWLGFQK
                     SSQVDILHSKCDEEEEVWNEEINEEDVDECAEDEGEDEVRVIEFKRKYREGSPLKEES
                     LAREDSPLSSPSSQPGTPDEQLVLGKKGDIARNSYSRYNTISYRKIRKGNTKQRIDEF
                     ESMMHL"
     exon            391..483
                     /gene="Ermn"
                     /gene_synonym="juxtanodin; RGD1308367"
                     /inference="alignment:Splign:2.1.0"
     exon            484..1780
                     /gene="Ermn"
                     /gene_synonym="juxtanodin; RGD1308367"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtaaaccttt agaaagaatc ttgccattgc atgtcaggct gagagtttaa ggtttggttt
       61 tagaactgta ggaaccacag cattagagct tatcaaatat ttgctcccat actttctctg
      121 ttgcttcctt aactcagacc taagggaaca tcatgacaga tactcctgtg acactgagtg
      181 gctcggagtg caatggggac agaccacctg agaatggcca acagcctagc agtcaaacca
      241 ggaagacaac tgatgcagat gagacccaga catactatgg ggttgaaccc agtcttcaac
      301 atttacctgc aaaagaaaat caagaagaaa gtggaaacag taaagggaac gtgctgccca
      361 gagggtcgga agatgagaag attctcaatg aaaacacaga ggagaacctc tttgttgttc
      421 accaggccat ccaagatctg tctctccaag aaacaagtgc agaagacaca gttttccaag
      481 aagggcatcc atggaagaag atccctctga acagccataa cctggacatg agtagacaga
      541 aggaaagaat tgtccaccaa catctagagc agagagaaga tgagagcgca gcccaccagg
      601 caactgaaat tgaatggctg gggttccaga aatctagtca agttgacata ttgcattcta
      661 aatgcgatga ggaagaagaa gtttggaatg aagaaataaa tgaggaagat gtcgatgagt
      721 gtgctgagga cgaaggtgaa gatgaagttc gagtaataga atttaagaga aaatacagag
      781 aaggttctcc actaaaagag gaaagccttg caagggagga ctccccacta agcagcccta
      841 gttcccagcc tgggaccccc gatgagcagc tggtgttagg aaagaaggga gatatcgcca
      901 ggaattctta ttccagatac aacacgatat cctatcggaa aatcaggaaa ggtaacacca
      961 aacagagaat tgatgagttt gagtcaatga tgcacttata aactaactgg gactgagaaa
     1021 tgtcaggagc attaaagaga agctaacttc taacttcctt ccactgagat atcttccact
     1081 gccttatttg caagatgtgc aagcttagta tctttttcac cataaagcaa tgtggaaata
     1141 accatagacc aaacacattc tggtaacttc aaaccaacaa gctttaaatt cattcctggg
     1201 tttttgcttt aaaaaacgca taactaatat aggatcaggt aagcattgtc ccagagccta
     1261 gcctggtaga atttgtattt aaaaacagta atagtaagag aggcagtcaa gggaacgagg
     1321 atagtagacg tgattctcat aattcttttg gtgtctttct ttcttcaggc caatgagaag
     1381 cctaaaatta aaccccacct ccattaaaca tggttttata gatcctgttt tttttctttt
     1441 ctatttatta taaaaaaaat attgtatctt aagtaggttt ccttggcatc tactgagtaa
     1501 aaattcagca gatctccttt ctagctgcaa ctgttcagtg aatttcctca ctaaaaggtt
     1561 aagcaattgt cagtcagaat tctgtttgct gagtgctggt cccagcttta tgcttgcaac
     1621 atgaattaaa cccattgcga agttgatcca gagagagcct agatgactgg tgagccacag
     1681 attagagatt tgtattggat ggttttattt tgttactgaa aacaaagtct tgtctagcac
     1741 aatgaaatca ttaaaaataa aaatggcaat tttagcacaa aaaaaaaaaa aaaaaaaaaa
     1801 aaaaa
//
