LOCUS       XM_039100085            4200 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ER membrane-associated RNA degradation
            (Ermard), transcript variant X3, mRNA.
ACCESSION   XM_039100085
VERSION     XM_039100085.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039100085.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4200
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4200
                     /gene="Ermard"
                     /gene_synonym="RGD1309374; RGD1562376"
                     /note="ER membrane-associated RNA degradation; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 11 ESTs, 2 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 34 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:361485"
                     /db_xref="RGD:1309374"
     CDS             120..1904
                     /gene="Ermard"
                     /gene_synonym="RGD1309374; RGD1562376"
                     /codon_start=1
                     /product="endoplasmic reticulum membrane-associated RNA
                     degradation protein isoform X3"
                     /protein_id="XP_038956013.1"
                     /db_xref="GeneID:361485"
                     /db_xref="RGD:1309374"
                     /translation="MEILTGDSITTCLSPLVHDLICNLGFELTEICDINSIVTQNGEV
                     RWKAITDRVSYAELGHSLDYRQSVQRLGPVCEAIHLHISSLSRAQFETQYSPWYQWTT
                     SPELFLEIYDALESSQSAAISLSVMKLASCLERALGDVFLLIGNECPFLLRDLLASAE
                     LAHVFGHAVMDVLKVFIGSPCGLNLRNVLWHGFASPQDIPPKFADCTMLLLSQLEAGL
                     RRVFATVNKCPDRLLTAESTILYTTFDEILAKHMSDGSINQLPCFLGEPAMDFLWDFL
                     NYQEGPRIRDRLSHGEINIREFPKAAASQLLTFCLVLLLRFTEEDTLSELKEEAAIQL
                     LVSLAERYRSRCHPAFQLQKQVLSCEKSLRMWPVLPLPEECCQEAGRSEGNSEACACN
                     SLISKILCELCHYLPASACAINGLDGLPSEKWSQLLNELCNTRIPTLFCPKIVLEVLV
                     VLRGISSQCQRVSDQVIASLQLRHRQWVEHTLRSRQRQNYVRMLSSVGLLCPVLSLIL
                     LLLALELVSVHAVHGKDAQERQQYLRFLKLILQYTENLVAYTSRQKNKWNEAVSLTRA
                     VLLRIWTFSEKKQMLIHLTKNTNKVDTG"
ORIGIN      
        1 gcatcccgga agttggagaa gagcgaagag gagcgagtca tcagagagcg ccgcatcccg
       61 gaaaccgggg aggagggacg cgcgagtcat cagaaagcgc cccgacctga gcggaagcga
      121 tggagatttt aacaggggat tccattacca catgcctttc tcctttagtg catgacttga
      181 tttgtaacct tgggtttgaa ctcactgaaa tttgtgatat caatagcatt gtaacccaaa
      241 atggtgaagt acgctggaaa gcaattacag accgtgtgag ctatgcagaa ttagggcaca
      301 gtctggacta caggcaaagt gtgcagcgct tgggtcctgt gtgtgaggcc atccatctac
      361 acatctcatc tctgagcaga gcacagtttg aaactcagta ttcaccatgg taccagtgga
      421 caacttctcc agagctgttt cttgaaatat acgatgcctt ggagagctcg cagtctgctg
      481 ccatctccct cagcgtgatg aaactagctt cctgtctgga acgagcctta ggcgatgtat
      541 ttttactgat tgggaatgag tgtccctttc tcctaagaga tcttcttgca tctgcagagc
      601 ttgcacatgt ctttggacat gctgtgatgg acgtactaaa agtcttcatc gggtctccct
      661 gtggactcaa cctgagaaac gtcttgtggc atggctttgc ttcccctcaa gatattcctc
      721 caaagtttgc cgactgcacc atgctgttgc tgtcacagct agaagctgga ctcaggagag
      781 tttttgctac agttaataaa tgtcctgata gactgctcac agctgagtca acaattctat
      841 ataccacgtt cgatgaaata ctagcaaaac acatgagtga tggtagcatc aaccagcttc
      901 cgtgtttcct gggggagcct gccatggact tcttgtggga tttcctgaac tatcaggagg
      961 gtcctcgtat ccgggatcgt ttaagccacg gggagatcaa catacgtgaa tttcccaaag
     1021 cagcagcaag ccagctgctc acattctgcc tggtgctcct gctcagattc actgaggagg
     1081 acacactgtc agaactaaag gaggaagcag caatacagtt gctggttagt cttgcagaac
     1141 gttacaggtc tcgctgccat ccagctttcc agctgcaaaa acaggtgctg agctgtgaga
     1201 aaagcctcag gatgtggcct gtgctgcctt tgccagaaga gtgctgtcag gaagcaggca
     1261 gatcggaagg taattcggaa gcatgtgcct gcaactcttt aattagcaag attctgtgtg
     1321 agctctgcca ctacctgcct gcgagtgcct gcgctataaa tggcttggac ggtcttccct
     1381 cagagaagtg gtcccagctg ctcaatgaac tctgtaacac acgcattcct acactgttct
     1441 gccccaaaat tgttctagaa gttctggttg tgctccgagg catcagctcc caatgccagc
     1501 gcgtatctga ccaggtcatc gcctctttgc agctgagaca caggcaatgg gtggagcaca
     1561 cgttgcgctc taggcagcgt cagaactatg tgcgcatgct cagcagtgtt ggacttttgt
     1621 gtcctgtgct ttccctgatt ttgttgctcc ttgcactgga attggtcagt gttcatgctg
     1681 ttcatggtaa agatgctcag gaacgacagc agtatctgag gttcttaaaa ctgatcctcc
     1741 aatacactga gaacctagtg gcctatacca gccgacagaa gaacaaatgg aatgaagccg
     1801 tcagtctcac acgtgcagtt ttgttgagaa tttggacgtt cagtgagaag aaacaaatgt
     1861 taatacattt aaccaaaaac acaaataaag ttgacacagg ctgacacgct ttctgtcaga
     1921 attgtcatct acgtgtttcc acacagaaga aaaggcttca catccagcac aattaagaaa
     1981 cacataccat ggtagtgcat gagtgaggcc aggtgataga agtttagagc cttcttttct
     2041 ccttacgtct tagtagagga agcagttgca tgatacatgt acaaattcaa ggttctgaaa
     2101 aatcttgagt tgatgattct tgttgattga aggtgctacc tgtatggccc cagccaattg
     2161 ccaagtgtac ttaaaaacaa ggctcaccct ggcctgcagt acctgtaggg ctgctcaggg
     2221 ctgaccaggt ctatgaagga aatagagaac agaagacaca gaaagcacat gtagaggttc
     2281 tgaaagataa tgaaataaac ggaatgactt cttcagcatg tagtcttcgg tactgtctcc
     2341 ctgttccatc aggacaagct gcttggtgaa caccactccg gaactctcta ggttttccaa
     2401 caggatctga gagcaaaaag aaccagagct gggggccatg ctatggagac tggtgggaga
     2461 tctcaggaag ctgacatccc acagaggctc tgccctgtat aaggcctggt tcaatcctgg
     2521 atcaagagat tcctcaactc ctgtgagtga cttctgccag tggcctctaa aagatacgaa
     2581 tcattctaag agtctgccta gaaaagaaaa cagaagcaca gaggccagcc agaaggaagg
     2641 ttggcagtgc agacccgatg ctagagaagt gagcatgctc catagtttac caggcttgag
     2701 ggcttgtctt tgtctgtgca gtgttgatgc tgaccctgcc atcacacacc tcatctaact
     2761 gacatgaggg aaggaaaagc gctgcagcag atgctttgct ctgtccctac aatatcaaca
     2821 gatgccagct tttcttgtcc ctcgtggacc atgatgggaa gtgatttgga ttctctgtta
     2881 cattgagatg tgtatgtgtg atgtgtgtat gttgctatgt gcatatcttc actgtatgtg
     2941 tctaacattc caacaattcc ccagccttac atgagttaac cattgggaaa atggtggcca
     3001 gcctcaagtc ctcacctgaa gtcccagttg aaagtagttt ttggttctgc caggtgagcc
     3061 ctttacctgt ggatctgaac ctggcacagg tagcgctttt gttaaccgtt ctggagtttg
     3121 ccaaaggtat gtatcccaac gggatcggag tgcttgtggg gcttctttct agctttactt
     3181 cccgagggaa tctcaggaac ccatgttaag gagaagtcac cttggaatgc aatgatgctg
     3241 gatttggaat tatagaacct cctaggtcca tttcctgatt gtgttttctc tagtcagaca
     3301 cagggcggcg ctcttcacta agtaatctga cagctgtgtg ggaagccgtc gcctgtgaat
     3361 tctcaggact ccaggaaaat gaattctttc ctgttcatct ggccacagag aggtagatcc
     3421 agggtgacaa gagtggggag tgaccgctgg cacccggcca ctggggctgt ggggcattgt
     3481 gtgcacctga aggctcggcc ttccgttcat ttaattctgt attgatgaaa ggcatgagca
     3541 atcacagtct gaaatctgtt ccatcttcat gagggaagat tggggttgta ctgtgtgaat
     3601 taatcccttt gggggagaca tcagcatggc tagtggtggt gacaggagaa taagggaggt
     3661 agcaaggtca ctattaacca accaccaatc accatactgc tgatggggga ggggaaccct
     3721 ttgtctaaag gaactgattg agctttgcag aggaaggggt gcagacctgc agtggagact
     3781 ggcttctaac cactcgctcg gtctccccag ctgcagtcag aagtcacacc tggacaccac
     3841 agtcagtcag ccaacactct gccaaagcag ggcgcccttg tgggattggc tcttagggac
     3901 taacaaagaa aattctttac aacagataaa agggagtgtc tgtggtttgg tttacagccc
     3961 tactaagtaa ttttaatgaa actaaatcac tgtggtacct ccagagtttg ggttttggag
     4021 gaaccagttt ctctgtgggc tgtgtctgga ttgtagagag cccatgtgaa ttaactggga
     4081 ccgattaaga taagtcttgg attgcatcag atgttctcca aataagaccc tggatgtata
     4141 caggatgtcc ccttgacaca tcaattaatt aatcggaaat gaaatatgct caattcaaaa
//
