LOCUS       XM_006227975            4408 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ER membrane-associated RNA degradation
            (Ermard), transcript variant X5, mRNA.
ACCESSION   XM_006227975
VERSION     XM_006227975.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006227975.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006227975.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4408
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4408
                     /gene="Ermard"
                     /gene_synonym="RGD1309374; RGD1562376"
                     /note="ER membrane-associated RNA degradation; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 9 ESTs, 2 long SRA reads, 5 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 41 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:361485"
                     /db_xref="RGD:1309374"
     CDS             454..2112
                     /gene="Ermard"
                     /gene_synonym="RGD1309374; RGD1562376"
                     /codon_start=1
                     /product="endoplasmic reticulum membrane-associated RNA
                     degradation protein isoform X4"
                     /protein_id="XP_006228037.1"
                     /db_xref="GeneID:361485"
                     /db_xref="RGD:1309374"
                     /translation="MKLASCLERALGDVFLLIGNECPFLLRDLLASAELAHVFGHAVM
                     DVLKVFIGSPCGLNLRNVLWHGFASPQDIPPKYCSALLLLTAGLGQLLKSYLHHTKVQ
                     LAHRPFVTLTNLEDVIVFPGVTDKVLSALETVMTKSSFLLKIMLPYWELAVSKFKSHR
                     FADCTMLLLSQLEAGLRRVFATVNKCPDRLLTAESTILYTTFDEILAKHMSDGSINQL
                     PCFLGEPAMDFLWDFLNYQEGPRIRDRLSHGEINIREFPKAAASQLLTFCLVLLLRFT
                     EEDTLSELKEEAAIQLLVSLAERYRSRCHPAFQLQKQVLSCEKSLRMWPVLPLPEECC
                     QEAGRSEGNSEACACNSLISKILCELCHYLPASACAINGLDGLPSEKWSQLLNELCNT
                     RIPTLFCPKIVLEVLVVLRGISSQCQRVSDQVIASLQLRHRQWVEHTLRSRQRQNYVR
                     MLSSVGLLCPVLSLILLLLALELVSVHAVHGKDAQERQQYLRFLKLILQYTENLVAYT
                     SRQKNKWNEAVSLTRAVLLRIWTFSEKKQMLIHLTKNTNKVDTG"
ORIGIN      
        1 cgcgcgagtc atcagaaagc gccccgacct gagcggaagc gatggaggta gggcggggcg
       61 ctgggtccta tcactcacct aattttaaca ggggattcca ttaccacatg cctttctcct
      121 ttagtgcatg acttgatttg taaccttggg tttgaactca ctgaaatttg tgatatcaat
      181 agcattgtaa cccaaaatgg tgaagtacgc tggaaagcaa ttacagaccg tgtgagctat
      241 gcagaattag ggcacagtct ggactacagg caaagtgtgc agcgcttggg tcctgtgtgt
      301 gaggccatcc atctacacat ctcatctctg agcagagcac agtttgaaac tcagtattca
      361 ccatggtacc agtggacaac ttctccagag ctgtttcttg aaatatacga tgccttggag
      421 agctcgcagt ctgctgccat ctccctcagc gtgatgaaac tagcttcctg tctggaacga
      481 gccttaggcg atgtattttt actgattggg aatgagtgtc cctttctcct aagagatctt
      541 cttgcatctg cagagcttgc acatgtcttt ggacatgctg tgatggacgt actaaaagtc
      601 ttcatcgggt ctccctgtgg actcaacctg agaaacgtct tgtggcatgg ctttgcttcc
      661 cctcaagata ttcctccaaa atactgttca gccttgttgc tgttgacagc aggactgggt
      721 cagttactga agagttacct tcaccacaca aaagtccagt tggcacatcg accttttgta
      781 acactcacaa acctagagga tgtgattgtt tttcctggtg tgactgacaa ggtactctca
      841 gcgttagaga cagtgatgac gaaatccagc tttctattaa aaatcatgtt gccatattgg
      901 gagctggcag tgagcaagtt taagtcgcac aggtttgccg actgcaccat gctgttgctg
      961 tcacagctag aagctggact caggagagtt tttgctacag ttaataaatg tcctgataga
     1021 ctgctcacag ctgagtcaac aattctatat accacgttcg atgaaatact agcaaaacac
     1081 atgagtgatg gtagcatcaa ccagcttccg tgtttcctgg gggagcctgc catggacttc
     1141 ttgtgggatt tcctgaacta tcaggagggt cctcgtatcc gggatcgttt aagccacggg
     1201 gagatcaaca tacgtgaatt tcccaaagca gcagcaagcc agctgctcac attctgcctg
     1261 gtgctcctgc tcagattcac tgaggaggac acactgtcag aactaaagga ggaagcagca
     1321 atacagttgc tggttagtct tgcagaacgt tacaggtctc gctgccatcc agctttccag
     1381 ctgcaaaaac aggtgctgag ctgtgagaaa agcctcagga tgtggcctgt gctgcctttg
     1441 ccagaagagt gctgtcagga agcaggcaga tcggaaggta attcggaagc atgtgcctgc
     1501 aactctttaa ttagcaagat tctgtgtgag ctctgccact acctgcctgc gagtgcctgc
     1561 gctataaatg gcttggacgg tcttccctca gagaagtggt cccagctgct caatgaactc
     1621 tgtaacacac gcattcctac actgttctgc cccaaaattg ttctagaagt tctggttgtg
     1681 ctccgaggca tcagctccca atgccagcgc gtatctgacc aggtcatcgc ctctttgcag
     1741 ctgagacaca ggcaatgggt ggagcacacg ttgcgctcta ggcagcgtca gaactatgtg
     1801 cgcatgctca gcagtgttgg acttttgtgt cctgtgcttt ccctgatttt gttgctcctt
     1861 gcactggaat tggtcagtgt tcatgctgtt catggtaaag atgctcagga acgacagcag
     1921 tatctgaggt tcttaaaact gatcctccaa tacactgaga acctagtggc ctataccagc
     1981 cgacagaaga acaaatggaa tgaagccgtc agtctcacac gtgcagtttt gttgagaatt
     2041 tggacgttca gtgagaagaa acaaatgtta atacatttaa ccaaaaacac aaataaagtt
     2101 gacacaggct gacacgcttt ctgtcagaat tgtcatctac gtgtttccac acagaagaaa
     2161 aggcttcaca tccagcacaa ttaagaaaca cataccatgg tagtgcatga gtgaggccag
     2221 gtgatagaag tttagagcct tcttttctcc ttacgtctta gtagaggaag cagttgcatg
     2281 atacatgtac aaattcaagg ttctgaaaaa tcttgagttg atgattcttg ttgattgaag
     2341 gtgctacctg tatggcccca gccaattgcc aagtgtactt aaaaacaagg ctcaccctgg
     2401 cctgcagtac ctgtagggct gctcagggct gaccaggtct atgaaggaaa tagagaacag
     2461 aagacacaga aagcacatgt agaggttctg aaagataatg aaataaacgg aatgacttct
     2521 tcagcatgta gtcttcggta ctgtctccct gttccatcag gacaagctgc ttggtgaaca
     2581 ccactccgga actctctagg ttttccaaca ggatctgaga gcaaaaagaa ccagagctgg
     2641 gggccatgct atggagactg gtgggagatc tcaggaagct gacatcccac agaggctctg
     2701 ccctgtataa ggcctggttc aatcctggat caagagattc ctcaactcct gtgagtgact
     2761 tctgccagtg gcctctaaaa gatacgaatc attctaagag tctgcctaga aaagaaaaca
     2821 gaagcacaga ggccagccag aaggaaggtt ggcagtgcag acccgatgct agagaagtga
     2881 gcatgctcca tagtttacca ggcttgaggg cttgtctttg tctgtgcagt gttgatgctg
     2941 accctgccat cacacacctc atctaactga catgagggaa ggaaaagcgc tgcagcagat
     3001 gctttgctct gtccctacaa tatcaacaga tgccagcttt tcttgtccct cgtggaccat
     3061 gatgggaagt gatttggatt ctctgttaca ttgagatgtg tatgtgtgat gtgtgtatgt
     3121 tgctatgtgc atatcttcac tgtatgtgtc taacattcca acaattcccc agccttacat
     3181 gagttaacca ttgggaaaat ggtggccagc ctcaagtcct cacctgaagt cccagttgaa
     3241 agtagttttt ggttctgcca ggtgagccct ttacctgtgg atctgaacct ggcacaggta
     3301 gcgcttttgt taaccgttct ggagtttgcc aaaggtatgt atcccaacgg gatcggagtg
     3361 cttgtggggc ttctttctag ctttacttcc cgagggaatc tcaggaaccc atgttaagga
     3421 gaagtcacct tggaatgcaa tgatgctgga tttggaatta tagaacctcc taggtccatt
     3481 tcctgattgt gttttctcta gtcagacaca gggcggcgct cttcactaag taatctgaca
     3541 gctgtgtggg aagccgtcgc ctgtgaattc tcaggactcc aggaaaatga attctttcct
     3601 gttcatctgg ccacagagag gtagatccag ggtgacaaga gtggggagtg accgctggca
     3661 cccggccact ggggctgtgg ggcattgtgt gcacctgaag gctcggcctt ccgttcattt
     3721 aattctgtat tgatgaaagg catgagcaat cacagtctga aatctgttcc atcttcatga
     3781 gggaagattg gggttgtact gtgtgaatta atccctttgg gggagacatc agcatggcta
     3841 gtggtggtga caggagaata agggaggtag caaggtcact attaaccaac caccaatcac
     3901 catactgctg atgggggagg ggaacccttt gtctaaagga actgattgag ctttgcagag
     3961 gaaggggtgc agacctgcag tggagactgg cttctaacca ctcgctcggt ctccccagct
     4021 gcagtcagaa gtcacacctg gacaccacag tcagtcagcc aacactctgc caaagcaggg
     4081 cgcccttgtg ggattggctc ttagggacta acaaagaaaa ttctttacaa cagataaaag
     4141 ggagtgtctg tggtttggtt tacagcccta ctaagtaatt ttaatgaaac taaatcactg
     4201 tggtacctcc agagtttggg ttttggagga accagtttct ctgtgggctg tgtctggatt
     4261 gtagagagcc catgtgaatt aactgggacc gattaagata agtcttggat tgcatcagat
     4321 gttctccaaa taagaccctg gatgtataca ggatgtcccc ttgacacatc aattaattaa
     4381 tcggaaatga aatatgctca attcaaaa
//
