LOCUS       NM_001014143            2896 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus exoribonuclease 1 (Eri1), mRNA.
ACCESSION   NM_001014143 XM_341445
VERSION     NM_001014143.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2896)
  AUTHORS   Henras,A.K., Plisson-Chastang,C., O'Donohue,M.F., Chakraborty,A.
            and Gleizes,P.E.
  TITLE     An overview of pre-ribosomal RNA processing in eukaryotes
  JOURNAL   Wiley Interdiscip Rev RNA 6 (2), 225-242 (2015)
   PUBMED   25346433
  REMARK    Review article
REFERENCE   2  (bases 1 to 2896)
  AUTHORS   Yang,X.C., Torres,M.P., Marzluff,W.F. and Dominski,Z.
  TITLE     Three proteins of the U7-specific Sm ring function as the molecular
            ruler to determine the site of 3'-end processing in mammalian
            histone pre-mRNA
  JOURNAL   Mol Cell Biol 29 (15), 4045-4056 (2009)
   PUBMED   19470752
REFERENCE   3  (bases 1 to 2896)
  AUTHORS   Ansel,K.M., Pastor,W.A., Rath,N., Lapan,A.D., Glasmacher,E.,
            Wolf,C., Smith,L.C., Papadopoulou,N., Lamperti,E.D., Tahiliani,M.,
            Ellwart,J.W., Shi,Y., Kremmer,E., Rao,A. and Heissmeyer,V.
  TITLE     Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA
            processing
  JOURNAL   Nat Struct Mol Biol 15 (5), 523-530 (2008)
   PUBMED   18438418
REFERENCE   4  (bases 1 to 2896)
  AUTHORS   Mullen,T.E. and Marzluff,W.F.
  TITLE     Degradation of histone mRNA requires oligouridylation followed by
            decapping and simultaneous degradation of the mRNA both 5' to 3'
            and 3' to 5'
  JOURNAL   Genes Dev 22 (1), 50-65 (2008)
   PUBMED   18172165
REFERENCE   5  (bases 1 to 2896)
  AUTHORS   Yang,X.C., Purdy,M., Marzluff,W.F. and Dominski,Z.
  TITLE     Characterization of 3'hExo, a 3' exonuclease specifically
            interacting with the 3' end of histone mRNA
  JOURNAL   J Biol Chem 281 (41), 30447-30454 (2006)
   PUBMED   16912046
REFERENCE   6  (bases 1 to 2896)
  AUTHORS   Dominski,Z., Yang,X.C., Kaygun,H., Dadlez,M. and Marzluff,W.F.
  TITLE     A 3' exonuclease that specifically interacts with the 3' end of
            histone mRNA
  JOURNAL   Mol Cell 12 (2), 295-305 (2003)
   PUBMED   14536070
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC089828.1.
            
            On Apr 20, 2005 this sequence version replaced XM_341445.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089828.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2896
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.2"
     gene            1..2896
                     /gene="Eri1"
                     /gene_synonym="RGD1308378; Thex1"
                     /note="exoribonuclease 1"
                     /db_xref="GeneID:361159"
                     /db_xref="RGD:1308378"
     exon            1..223
                     /gene="Eri1"
                     /gene_synonym="RGD1308378; Thex1"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..1165
                     /gene="Eri1"
                     /gene_synonym="RGD1308378; Thex1"
                     /note="3' exoribonuclease; histone mRNA 3'-exonuclease 1;
                     3 ' exoribonuclease; three prime histone mRNA exonuclease
                     1"
                     /codon_start=1
                     /product="3'-5' exoribonuclease 1"
                     /protein_id="NP_001014165.1"
                     /db_xref="GeneID:361159"
                     /db_xref="RGD:1308378"
                     /translation="MEDERGREHGGDAAQQKTPRPECEESRPLSVEKKQRCRLDGKDT
                     DGSKFITSNGGDFSDPVYKEIAMTNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRL
                     KNYYKKQKLMLKESNAVDSYYDYICIIDFEATCEEGNPAEFLHEIIEFPVVLLNTHSL
                     EIEDTFQQYVRPEVNSQLSEFCIGLTGITQDQVDRADAFPQVLKKVIEWMKSKELGTK
                     YKYCILTDGSWDMSKFLNIQCQLSRLKYPSFAKKWINIRKSYGNFYKVPRSQTKLTIM
                     LEKLGMDYDGRPHSGLDDSKNIARIAVRMLQDGCELRINEKLHGGQLMSVSSSLPVEG
                     APAPQMPHSRK"
     exon            224..402
                     /gene="Eri1"
                     /gene_synonym="RGD1308378; Thex1"
                     /inference="alignment:Splign:2.1.0"
     exon            403..613
                     /gene="Eri1"
                     /gene_synonym="RGD1308378; Thex1"
                     /inference="alignment:Splign:2.1.0"
     exon            614..697
                     /gene="Eri1"
                     /gene_synonym="RGD1308378; Thex1"
                     /inference="alignment:Splign:2.1.0"
     exon            698..807
                     /gene="Eri1"
                     /gene_synonym="RGD1308378; Thex1"
                     /inference="alignment:Splign:2.1.0"
     exon            808..922
                     /gene="Eri1"
                     /gene_synonym="RGD1308378; Thex1"
                     /inference="alignment:Splign:2.1.0"
     exon            923..2871
                     /gene="Eri1"
                     /gene_synonym="RGD1308378; Thex1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggagtttgt gtgacggccg ccgcgggaac gtgagcgcgg tagtttttca agggagaaag
       61 gcggcttcgt ggggctcggt ggagtgacag cgagcgtcag cggccatctc ccggcgcgag
      121 aggcggcatg gaggacgagc ggggccggga gcatggcggc gacgcggcgc agcagaagac
      181 gccgcggcca gagtgtgagg agtcccggcc gctgagcgtg gagaaaaagc agcgatgcag
      241 acttgatggc aaagacacag atggatctaa gttcataacc tccaatggcg gtgacttcag
      301 tgacccggtt tacaaagaga ttgcaatgac aaatggttgt atcaacagga tgagcaagga
      361 ggagctcaga gctaaacttt cagaattcaa gcttgaaaca agaggagtca aggatgttct
      421 aaagaagaga ctgaaaaact attacaagaa gcagaagctg atgctgaaag aaagcaacgc
      481 cgtggacagt tactatgact atatttgtat tattgacttt gaggccacct gtgaagaggg
      541 gaacccagcc gagttcctac atgaaattat tgagtttcct gttgttctgt tgaatacaca
      601 cagcttagag atcgaagaca cgtttcagca gtatgtgaga ccagaggtga attctcagct
      661 ttcagagttc tgcattggtc ttactggaat tactcaggat caggtagaca gagccgatgc
      721 tttccctcag gtcctgaaaa aagtaatcga gtggatgaag tcaaaggagt tgggaactaa
      781 gtacaaatac tgcatattaa cagatggttc ctgggatatg agtaagttct taaacatcca
      841 gtgccaacta agcagactca agtacccttc ttttgctaaa aagtggatca atattcgcaa
      901 gtcttacgga aacttttata aggttccaag aagccagacc aaactaacaa taatgcttga
      961 aaaattaggc atggattatg atgggcgacc tcacagtggt cttgatgact ctaagaacat
     1021 tgctagaata gcggttcgga tgcttcagga tggatgtgaa cttcgaatca atgaaaaact
     1081 gcacggagga cagctaatga gtgtgtcctc atccttacca gtagagggcg ctccagcccc
     1141 acagatgccg catagtagaa agtaactacg tttttgtctg gatcagttgc tacaaaggta
     1201 gcaagtgaat gaatctgagc tagtacaacc ttcaagcacc ttaaacgttt cctacagtta
     1261 cagatagatg gtatgtatgc agacattttg tgggagggca caccagatcc tttgtcacca
     1321 gcacttttga tatgagcagt aaccagtcac acacagtaac cagtcccagc ttagaactga
     1381 attttataat gtaaggagtc cgagatgtgt tcctttgctt ttcaggtgga agatttattg
     1441 gttcatgctt tgaacgtcat gtcttactga tactgaaatt taaaatgatt ttctacatta
     1501 ccaccattaa attaaataca ttttttgaaa gtgtggaaag gattgaaagg cagtgtttac
     1561 ccattgaatt ttaagtaaag tgtggtcctt ttaactttgt aagtttgtag gtgaagttaa
     1621 ggggttacca gtgagaggtt tgttccagga atgctgtgtg tgcgtaccag attctccagg
     1681 tgttcaagtt ctgtacttca gatggcataa tgtttatata tcacctgcac atattccccc
     1741 atatatttta atgatctcta ggtagcttat acttaataaa cgataatcct tcagggaata
     1801 atgatcagaa aaaaagtctg caagttggtg tagacacacc catagtgggc ctccctacac
     1861 agcacatgag taagttgctc agccagcccg atctgggaag aaactaagga tctgagacag
     1921 aggtgacagc agctgtcccg tgtgtcactc actctgctcc attcaacaaa gtgctcgctg
     1981 agcagcaaat tcaggtgttt ctttttggaa cattttctgc atatctgtat ctgttcctgt
     2041 gttcaggcca gggaatcatt tctgaaggag cgtaccttga cagcctgaat ttgatcccca
     2101 gaacacacat gatagacaga attaactcaa ggatgtcccc tgattcccaa catgcacacc
     2161 gttggaattg ctcccacata tacatgcata tgtgtccaag taagcaaaat gtaataaagt
     2221 actgggatct catctcataa ctggaaacct tataataggc cataggatct agtttaaagt
     2281 ctagttactg gagagcacag atgactcagt ggttaagatc acttgctgct cctttagaag
     2341 acccaggttc aagtcaaaga atccaacagg cagaacattc ataagcataa aataactaaa
     2401 atactgggca ggggaaatgg ctcagaggtt aagggtgctg gctgctcttt cagaggtcct
     2461 gggttcagtt cctagcataa gtgaatctga ggccatcctg ggccattaat gagaccctga
     2521 ctctaaaaag tgttagtagg aaatacaagt gaaattatga gagctataac ttactaatca
     2581 atgggagatt ctgaaaattt gctcattggc ttccctctcc tttgtgaatg tgccctgctt
     2641 tgcgattgac ttacagctca tggtaaacat ttgttgtatt cagtactgtg aggtgaaatg
     2701 ttttgtgcca tagttattaa acctggcttg tcttagtgag tgaccagtat atattgggaa
     2761 ataattccta tttctaaaat caaactgtgc tctggagata atgatgtaaa actatctaga
     2821 ggctgaaagt atggacttac ggaattaaac ccttctcgcg attttcatgg aaaaaaaaaa
     2881 aaaaaaaaaa aaaaaa
//
