LOCUS       NM_001170335            3711 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus Ets2 repressor factor (Erf), mRNA.
ACCESSION   NM_001170335 XM_001077208 XM_218336
VERSION     NM_001170335.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3711)
  AUTHORS   Jolma,A., Yan,J., Whitington,T., Toivonen,J., Nitta,K.R.,
            Rastas,P., Morgunova,E., Enge,M., Taipale,M., Wei,G., Palin,K.,
            Vaquerizas,J.M., Vincentelli,R., Luscombe,N.M., Hughes,T.R.,
            Lemaire,P., Ukkonen,E., Kivioja,T. and Taipale,J.
  TITLE     DNA-binding specificities of human transcription factors
  JOURNAL   Cell 152 (1-2), 327-339 (2013)
   PUBMED   23332764
REFERENCE   2  (bases 1 to 3711)
  AUTHORS   Papadaki,C., Alexiou,M., Cecena,G., Verykokakis,M., Bilitou,A.,
            Cross,J.C., Oshima,R.G. and Mavrothalassitis,G.
  TITLE     Transcriptional repressor erf determines extraembryonic ectoderm
            differentiation
  JOURNAL   Mol Cell Biol 27 (14), 5201-5213 (2007)
   PUBMED   17502352
REFERENCE   3  (bases 1 to 3711)
  AUTHORS   Sgouras,D.N., Athanasiou,M.A., Beal,G.J. Jr., Fisher,R.J.,
            Blair,D.G. and Mavrothalassitis,G.J.
  TITLE     ERF: an ETS domain protein with strong transcriptional repressor
            activity, can suppress ets-associated tumorigenesis and is
            regulated by phosphorylation during cell cycle and mitogenic
            stimulation
  JOURNAL   EMBO J 14 (19), 4781-4793 (1995)
   PUBMED   7588608
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Dec 19, 2009 this sequence version replaced
            XM_218336.4, XM_001077208.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643287.770.1,
                                           SRR26643299.1625.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760400,
                                           SAMN12840109 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-183               JAXUCZ010000001.1  89966031-89966213   c
            184-418             JAXUCZ010000001.1  89961510-89961744   c
            419-534             JAXUCZ010000001.1  89961047-89961162   c
            535-3711            JAXUCZ010000001.1  89957760-89960936   c
FEATURES             Location/Qualifiers
     source          1..3711
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..3711
                     /gene="Erf"
                     /note="Ets2 repressor factor"
                     /db_xref="GeneID:292721"
                     /db_xref="RGD:1311991"
     exon            1..183
                     /gene="Erf"
                     /inference="alignment:Splign:2.1.0"
     CDS             162..1820
                     /gene="Erf"
                     /codon_start=1
                     /product="ETS domain-containing transcription factor ERF"
                     /protein_id="NP_001163806.1"
                     /db_xref="GeneID:292721"
                     /db_xref="RGD:1311991"
                     /translation="MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQG
                     VIAWQGDYGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRF
                     TYKFNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPR
                     SPPACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPELGAFR
                     GPPLARLPHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLA
                     YTPSPTLSPMYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHY
                     PGLVVPQPQRPDKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAG
                     EKAPGGTDKSSDGSGSGGLAEGAGALAPPPPPPPQIKVEPISEGESEEVEVTDISDED
                     EEDGEVFKTPRAPPAPPKPEPGEAPGAAQCMPLKLRFKRRWSEDCRLEGGGCLSGGPE
                     DEGEDKKVRGDMGPGEPGGPLTPRRVSSDLQHATAQLSLEHRDS"
     exon            184..418
                     /gene="Erf"
                     /inference="alignment:Splign:2.1.0"
     exon            419..534
                     /gene="Erf"
                     /inference="alignment:Splign:2.1.0"
     exon            535..3711
                     /gene="Erf"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gatattaacc cgggaggcgg cggcggggag gggagaggct ctgagaggcg aggccgggtg
       61 cggcggcgag ggcgtcccaa cgggcgcggg acgggacggg gcaacgcggg cgcctggagc
      121 agcggcccgg agtcggggcg ccttgccccg ggccccccag catgaagacc ccagcggaca
      181 cagggtttgc cttcccagat tgggcctaca agccggagtc atcccctggc tcgaggcaga
      241 tccagctgtg gcactttatc ttggagctgc ttcggaaaga ggagtaccag ggcgtcatcg
      301 cctggcaggg agactacggg gaatttgtca tcaaggaccc tgatgaggtg gcccgactct
      361 ggggggtccg caagtgcaaa ccccagatga actacgacaa gctgagccgg gccctgcgct
      421 attactataa caagcgcatt ctgcacaaga ccaaggggaa acggttcacc tacaagttca
      481 acttcaacaa actggtgctg gttaattacc ctttcatcga tgtggggctg gccgggggcg
      541 ctgttcccca gagtgcccct ccagtgccat cgggcggcag ccatttccgc ttccctcctt
      601 cgacgccctc cgaggtgctg tcccccaccg aggatccccg ctctccacca gcttgttctt
      661 catcgtcctc ttctctcttc tccgctgtgg ttgctcgacg cctgggccga ggctctgtca
      721 gcgactgcag tgatggcacc tcagagctgg aggagcctct gggggaggac cccagggcac
      781 gaccacctgg ccctccggag ctgggtgcct tccgagggcc cccgctggcc cgcctcccac
      841 atgatcctgg tgtcttccgt gtctatcctc ggcctcgggg tggtcctgaa cccctaagtc
      901 ccttccctgt gtcacctttg gctgggcctg gctcccttct accccctcaa ctctccccag
      961 ctctgcccat gactcccacc cacctggcct acacaccctc acccacgctg agtcctatgt
     1021 accccagtgg tggcgggggc cctagtggct cagggggggg ttcccacttc tccttcagtc
     1081 cggaggacat gaaacggtac ctgcaggccc acacccaaag cgtctacaac taccacctca
     1141 gtccccgcgc cttcctgcac tatccagggc tggtggtgcc ccagcctcag cgccctgaca
     1201 agtgcccact gccgcccatg gcaccggaga ccccgccggt tccctcctca gcctcgtctt
     1261 cctcttcttc ctcttcatcc ccgttcaagt ttaagctgca gccacccccg ctaggacgcc
     1321 ggcagcgggc agctggagag aaggctccag ggggcactga caagagcagt gatggtagtg
     1381 gctctggtgg gctggccgag ggggcaggcg cattagcccc cccaccgcca ccaccacccc
     1441 agattaaggt ggaacccatc tcagagggcg agtcggagga ggtggaggtg actgacatca
     1501 gtgacgaaga tgaggaagat ggggaggtgt tcaagacccc ccgtgcccca cccgctcccc
     1561 ccaagccaga gcctggagag gcaccagggg cagcccagtg catgcctctt aaactgcgct
     1621 ttaaaaggcg ctggagtgaa gactgtcgcc tggagggggg cgggtgcctc tctgggggcc
     1681 ctgaggatga gggtgaggac aagaaggtgc gtggggacat gggccctggg gagcctgggg
     1741 gacccctcac tcctcggcga gtgagctctg atctccagca cgctacagcc cagctctccc
     1801 tggagcaccg agattcctga gagccgtggg caagggcccg gtgcgccacc cccaactacc
     1861 ccactccccc tgagcttttg ctgccttaac cccccccccc ccagccctgg aggtgagggc
     1921 agctctcttt agtctcctcc ctgcctcctc cctttctcct cccccacatt ttgtataaaa
     1981 ctttgaattt tttttttaat ggtagggtgg gtgggtgccc agagctgggg gctaatctcc
     2041 tcttctctgg gtttctaagt tctgggcaaa gtggtggtgg ggggtgggag ggggggtctt
     2101 aaaggggggg cacctccatt ctggggattt ctatttgaac agaggctttg gccttaaaac
     2161 ccaggaactt ttttattaca atcgtaggaa gtaaagcctt gtctccctcc ctcttctctg
     2221 cctcttacct cgtcctgcct ctccccccct cgtgcccctc ccccagccct aaccctgcct
     2281 tccttgcccc tccaggggct gtgagtgcct gggtttctta taccccataa ggttgcagca
     2341 gaggcaggag ggacaaattt tataaaccaa aaattctgtg gggggtggtg gggtgggggg
     2401 cagaggaagg tgaggggtgc cgcctatggg ccacaaatct ctacaagtgc ctgttcccta
     2461 caccacccca gtactagtcc agtcccttca cacccactcc cagctgctcc taggtctggc
     2521 ccatgggcag gtgggtcaag ggacaggaag ggggggtccc tcaaaaccaa actggaagcc
     2581 cctctctgcc tcccagctgg ggccccaggg gtgggctgga gggttttggt caagccttat
     2641 tctgtattgg gaatggaggg tggggtggga catgaggggg ctgctggaga atgtattcaa
     2701 aacaataaaa ctttggacct ttgcatgtgg taatgcatcc taggtgctgg gtacagccac
     2761 agtatcaaca cagacttggt ttgcttctgg acaggtctag acacctgctt ctatctgtgg
     2821 ccagaaggtc tgactccacc tgaacaggtc agctaggcct ggggagttac tggcctactt
     2881 tcagatgtca caaacctcgg agcggatgat taaggtttct ggctttctct agtcttgtgt
     2941 ttccttgact ggttccttat ctcatctgcc tcttggaccc ttaacatgac cctgctgttc
     3001 ctggctctcc tacctgaatc gcatttgccc tccagctctg gctgctaagc cacacccgtc
     3061 agggccccag ggaaggaagg gtcgtgtatt ttggaccaag gccagcttct tgctcatctc
     3121 cctcaaaatg tacggaagag gctttagtgg tccacacctg taatcccccc agcactggtg
     3181 ttaggaagtt taaggttatg gcctgcctgg accatgtaaa agggaaatgt gtgatcctgc
     3241 ttcggagcct tggacccgga ggcctggagt gtcttgaaat gcagcccttg ggctggagcg
     3301 ccgctcagct ctgtgttcaa gggtgcttcc actcttgaga gaacctcagt tcatttcaga
     3361 gtactttacg tggggtggct catgacagtt ggcaccccca gttccagggg atccagcttc
     3421 tggcacccac acagaattgg catacattta ctcagacaca ttaacaaaaa tattttaaga
     3481 aatttatacc tatgcatatg aacgtttggt ccgtatgcat atccatgtat catgtgctct
     3541 gtgcccaaga tggtcagaaa agggcgtcgg atgtcctgga aggacagaaa gatggtttcg
     3601 aaccgacatg tgggtgctgg gaaccaaccc tgggtcatct gcaagagcag caagtgctct
     3661 tagccaccaa gccatctttc cagccccaat aaaacttatg tcttaaagga a
//
