LOCUS       NM_001098674            4000 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus ERCC excision repair 6 like, spindle assembly
            checkpoint helicase (Ercc6l), mRNA.
ACCESSION   NM_001098674 XM_228546
VERSION     NM_001098674.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4000)
  AUTHORS   Hou,G., Lu,Z., Bi,Y., Deng,J. and Yang,X.
  TITLE     ERCC6L is a biomarker and therapeutic target for non-small cell
            lung adenocarcinoma
  JOURNAL   Med Oncol 39 (5), 51 (2022)
   PUBMED   35150321
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4000)
  AUTHORS   Xie,Y., Yu,J., Wang,F., Li,M., Qiu,X., Liu,Y. and Qi,J.
  TITLE     ERCC6L promotes cell growth and invasion in human colorectal cancer
  JOURNAL   Oncol Lett 18 (1), 237-246 (2019)
   PUBMED   31289493
REFERENCE   3  (bases 1 to 4000)
  AUTHORS   Biebricher,A., Hirano,S., Enzlin,J.H., Wiechens,N., Streicher,W.W.,
            Huttner,D., Wang,L.H., Nigg,E.A., Owen-Hughes,T., Liu,Y.,
            Peterman,E., Wuite,G.J.L. and Hickson,I.D.
  TITLE     PICH: a DNA translocase specially adapted for processing anaphase
            bridge DNA
  JOURNAL   Mol Cell 51 (5), 691-701 (2013)
   PUBMED   23973328
REFERENCE   4  (bases 1 to 4000)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 4000)
  AUTHORS   Xu,Y., Chen,X. and Li,Y.
  TITLE     Ercc6l, a gene of SNF2 family, may play a role in the teratogenic
            action of alcohol
  JOURNAL   Toxicol Lett 157 (3), 233-239 (2005)
   PUBMED   15917148
  REMARK    GeneRIF: Characterization of the mouse Ercc6l ortholog.
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000021.1.
            
            On Sep 25, 2012 this sequence version replaced XM_228546.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.434368.1,
                                           SRR26360181.2351154.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-137               JAXUCZ010000021.1  71301050-71301186   c
            138-4000            JAXUCZ010000021.1  71285380-71289242   c
FEATURES             Location/Qualifiers
     source          1..4000
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq22"
     gene            1..4000
                     /gene="Ercc6l"
                     /gene_synonym="RGD1565734"
                     /note="ERCC excision repair 6 like, spindle assembly
                     checkpoint helicase"
                     /db_xref="GeneID:317252"
                     /db_xref="RGD:1565734"
     exon            1..137
                     /gene="Ercc6l"
                     /gene_synonym="RGD1565734"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..3762
                     /gene="Ercc6l"
                     /gene_synonym="RGD1565734"
                     /EC_number="3.6.4.12"
                     /note="excision repair cross-complementing rodent repair
                     deficiency complementation group 6-like; excision repair
                     cross-complementing rodent repair deficiency
                     complementation group 6 - like; excision repair
                     cross-complementation group 6-like"
                     /codon_start=1
                     /product="DNA excision repair protein ERCC-6-like"
                     /protein_id="NP_001092144.1"
                     /db_xref="GeneID:317252"
                     /db_xref="RGD:1565734"
                     /translation="MEASQGLAEVGTLSPQLAESYLRYSQEAKEAAKNGDLEEALKLF
                     NLAKDIFPTKKVISRIQKLQEALEQLAEEEDDEFTDVCNSGLLLYRELYEKLFEHQKE
                     GIAFLYSLYKNGRKGGILADDMGLGKTVQIIAFLSGMFDASLVNHVLLIMPTNLINTW
                     VKEFAKWTPGMRVKTFHGSSKNERIRNLTRIQQRNGVVITTYQMLLNNWQQLASFNGQ
                     AFVWDYVILDEAHKIKSASTKSAVCARAVPASNRLLLTGTPIQNNLQELWSLFDFACQ
                     GSLLGTLKTFKMEYENPIIRAREKDATPGEKALGFKMSENLMEIIKPYFLRRTKEEVH
                     MKKADKPEVRPGEKNSGVEDICEMLSLTRKNDLIVWIRLVPLQEEIYRKFVSLDHIKE
                     LLMETRSPLAELGVLKKLCDHPRLLSARACHLLNLGTVTFSAEDENEQEDASNMGSID
                     HLSDNALMQESGKMIFLMALLERLQDEGHQTLVFSQSRQILNIIERLLKNKHFKTLRI
                     DGTVTHLWEREKRIQLFQQNKEYSVFLLTTQVGGVGLTLTAASRVVIFDPSWNPATDA
                     QAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYFTKQ
                     ELKELFTVGDLLNSATQMQLQCLHAAQRKSDEKLDEHIAYLHSLGIAGISDHDLMFTC
                     DLSVKEELDMLEDAQYIQHRVQKAQFLVESESQNTKERPSEENWLKAQEFPSQQRKKG
                     NKPQPQPSRLLANPTQVEAISSQMASISIYDQSTESEPQELSEAHDVTSLQGDQHHFE
                     STSDAGTIASLPQGAESIGGVWTDSLLSPAKGFAADNEAVQKNELQASPGQEALSENL
                     GSFHYLPRQSSKADLEPNLDVQDSVVLYHQSPTANENQNLESNEPMIEISDDLSASPS
                     ALQGAQAMEAQLELKKDPLESPPQYECDFNLFLEDSADTRQNLSSKFLEHVEKENSLQ
                     RPAGNSGEESAHNLSLDSSNKIDEESEVITVKTKNKARRILSDDEDEEDAFKDTSTNS
                     FSVSPLTFSSVKHFDASTPQNDSNPSRRFFSPKIPDDVNTSLHPRRSLASRRSLINVV
                     LDDMEDMEERLDTSSEEESEPELSEDSNEEAVACTEEQRSGATLASGNKHSSLTESEP
                     TSPAPQSSPCAPEPSSSDPLLDPPQDPAVEAANDYESLVARGKELKECGKTQEALNCL
                     VKALDIKSADPEVMRMTLSLYKQLNT"
     exon            138..4000
                     /gene="Ercc6l"
                     /gene_synonym="RGD1565734"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgggagcga gcgaaattca agcgcgactt ggagaatccg gtttccttgg ctttctagtt
       61 tcctgggcca tggaggcttc ccaaggttta gcggaagtgg ggactttgag cccacaactg
      121 gctgagagtt acctgagata ttcgcaagaa gccaaagaag cagctaagaa tggagatctg
      181 gaagaagcac tgaaactttt caatttggca aaggacattt ttcccaccaa gaaggtgatc
      241 agcagaatcc agaaactaca ggaagctttg gagcagttgg cagaagaaga agatgatgaa
      301 tttacagatg tgtgcaactc cggcttgctg ctttaccgag agctctatga gaaactcttt
      361 gagcaccaga aagaaggcat cgcttttctc tatagcctgt ataagaatgg aagaaaaggg
      421 ggcatcttag cagatgatat gggattgggg aaaactgttc agatcattgc tttcctgtca
      481 ggtatgtttg atgcttcact tgtgaatcat gtgctattga tcatgccaac caatctcatt
      541 aatacatggg tcaaagaatt tgccaagtgg actccaggaa tgagagtcaa aacctttcat
      601 ggctctagca agaatgaacg cattagaaac ctgacccgga ttcaacagag gaatggtgtt
      661 gtgatcacta cctaccaaat gttactcaat aattggcagc aacttgcaag ctttaatgga
      721 caagcatttg tttgggacta tgtcatcctt gatgaagccc ataagatcaa aagtgcctct
      781 accaagtcag cagtatgtgc ccgagcagtt cctgcaagta atcgtctcct tctcacagga
      841 acaccaatcc agaataatct gcaagaactg tggtccctgt ttgattttgc ttgccaaggc
      901 tccttgttag gaacattaaa aacttttaaa atggagtatg aaaatcctat tattagggca
      961 agagagaagg atgctacccc tggggaaaaa gccttgggat ttaagatgtc tgaaaactta
     1021 atggaaatta taaaacccta ttttctaagg aggaccaaag aagaagtgca catgaaaaag
     1081 gcagacaagc cagaggtcag acctggtgaa aagaattcag gcgtcgaaga catttgtgag
     1141 atgctttccc ttaccaggaa aaatgattta attgtttgga tacgtcttgt gcctttacaa
     1201 gaggaaattt ataggaagtt tgtgtcttta gaccacatca aggagttgtt aatggagaca
     1261 cgctcacctc tggctgagct gggtgtctta aagaagctct gtgaccatcc taggctgcta
     1321 tctgcacgag cttgtcattt gctgaatcta gggactgtca cattctctgc ggaggatgaa
     1381 aatgagcaag aagatgcctc aaatatgggc agcattgatc acttaagtga caatgcactg
     1441 atgcaggagt ctggaaaaat gatattctta atggccctgc tagagaggct tcaagatgaa
     1501 ggacatcaga ctctggtgtt ttcccagtcg aggcaaattc tcaacatcat tgagcgtctc
     1561 ttaaagaaca agcactttaa gacattgcga attgatggca cagttactca tctttgggaa
     1621 cgagaaaaaa gaattcagtt attccagcaa aataaagaat actcagtttt tctacttacc
     1681 actcaagtag gtggtgttgg actgacactg actgcagcat ctagagttgt catttttgac
     1741 cctagctgga accctgcaac tgatgctcaa gctgtggata gagtttaccg aattggacaa
     1801 aaagagaatg ttgtggttta tcggctaatc acttgtggaa ctgtagagga aaagatatat
     1861 agaagacagg ttttcaagga ctcgttgatc agacaaacta ctggtgataa gaagaatcca
     1921 ttccgctatt tcaccaaaca ggagctaaag gagctcttca cagttgggga tctgctgaac
     1981 tctgcaaccc agatgcagct tcagtgtctg catgctgctc agcggaaatc tgatgagaaa
     2041 ctcgatgagc atatcgccta cctacactcg ctgggcatag caggaatctc agaccacgat
     2101 ttgatgttca cctgtgatct gtctgttaaa gaagagcttg acatgctaga agacgctcag
     2161 tacattcaac acagagttca gaaagctcag ttccttgttg aatctgagtc tcaaaataca
     2221 aaggaaagac caagtgagga gaactggctc aaagcacagg aatttccttc tcaacagagg
     2281 aagaaaggta acaaacccca gcctcagcct tcacgccttc tggctaatcc tacgcaggta
     2341 gaggctatca gttctcaaat ggccagtata agcatttatg atcagtctac agagagtgag
     2401 ccccaagagc tctctgaggc acatgatgtc acttcactgc aaggtgatca gcaccacttc
     2461 gaaagtacat ctgatgctgg cactatcgct tctttacccc agggggctga aagtataggg
     2521 ggagtttgga ctgactcctt attgagccct gcaaaaggtt ttgcagctga caatgaagcc
     2581 gtgcagaaga atgaattaca agcatcacct gggcaagagg ccctgtcaga gaacctggga
     2641 agttttcatt atttacctag acagtccagc aaggctgatc ttgagccaaa tttagatgta
     2701 caggatagtg tggttttata tcaccaaagt cccacagcaa atgaaaatca aaacctagaa
     2761 tcaaatgaac ccatgattga aatatctgat gatttgtcag catccccgag tgcactgcag
     2821 ggtgctcaag caatggaggc ccagttggaa ttgaaaaagg accctttaga atcaccacca
     2881 cagtatgagt gtgacttcaa tcttttcctg gaagactctg cagacactag acaaaatctc
     2941 tccagcaaat ttttggaaca tgttgagaaa gaaaatagct tgcaaaggcc tgcaggtaac
     3001 tccggggaag agtcagcaca taatctcagt ttggattctt ctaataaaat tgatgaagaa
     3061 tcagaagtga ttactgtgaa aaccaaaaac aaagctagaa ggatcctctc agatgatgaa
     3121 gatgaagaag atgcctttaa agatacttcc acaaattcat ttagcgtctc tcccttaaca
     3181 ttctcatctg tcaaacactt tgatgcttca actccccaaa atgacagtaa tccatctcga
     3241 aggttcttct cacctaaaat acctgatgat gtgaacacat ccttacatcc taggaggtct
     3301 ctggcttcta ggaggtctct gatcaatgtg gttttagatg acatggaaga tatggaggaa
     3361 aggcttgata ccagtagcga ggaggaaagt gaaccagagc tttcagaaga cagcaatgaa
     3421 gaagccgtag cctgcactga agagcagcgt tccggggcaa cactggcttc aggaaacaag
     3481 cacagcagcc tgaccgagtc tgagcctact tctccagccc cacaaagctc tccctgtgcc
     3541 cctgaacctt catcaagtga ccctttgctt gatcctcccc aggatccggc agtggaggct
     3601 gctaatgact atgagagtct tgtagctcgt gggaaagaac tgaaagagtg tgggaagaca
     3661 caggaggctc tcaactgctt agttaaagca cttgatataa aaagtgcaga tcctgaggtc
     3721 atgcgcatga ctctgagttt gtataagcaa cttaacactt gaaaacttta tagcctattt
     3781 cttacatcta aaatgaaatt gaatataaat gttttgctca gtagttcttc ccttgaatat
     3841 ttcatttttt ccctttaggc atactttgca aactttcaga ggtgttactt ttaattgata
     3901 ttacctaaag tttttgtgaa gctattgcgg ctatttttac tctgaaaagg accatcttgt
     3961 ctgttagctc agttctgaaa attaaagtga cttttctcaa
//
