LOCUS       NM_001109375            1066 bp    mRNA    linear   ROD 26-OCT-2024
DEFINITION  Rattus norvegicus ES cell expressed Ras (Eras), transcript variant
            2, mRNA.
ACCESSION   NM_001109375 XM_001053996
VERSION     NM_001109375.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1066)
  AUTHORS   Nakhaei-Rad,S., Nakhaeizadeh,H., Gotze,S., Kordes,C., Sawitza,I.,
            Hoffmann,M.J., Franke,M., Schulz,W.A., Scheller,J., Piekorz,R.P.,
            Haussinger,D. and Ahmadian,M.R.
  TITLE     The Role of Embryonic Stem Cell-expressed RAS (ERAS) in the
            Maintenance of Quiescent Hepatic Stellate Cells
  JOURNAL   J Biol Chem 291 (16), 8399-8413 (2016)
   PUBMED   26884329
  REMARK    GeneRIF: findings indicate that ERAS is important to maintain
            quiescence in HSCs.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474078.1.
            
            On Oct 4, 2007 this sequence version replaced XM_001053996.1.
FEATURES             Location/Qualifiers
     source          1..1066
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq12"
     gene            1..1066
                     /gene="Eras"
                     /note="ES cell expressed Ras"
                     /db_xref="GeneID:679682"
                     /db_xref="RGD:1585907"
     exon            1..139
                     /gene="Eras"
                     /inference="alignment:Splign:2.1.0"
     exon            140..1066
                     /gene="Eras"
                     /inference="alignment:Splign:2.1.0"
     CDS             178..861
                     /gene="Eras"
                     /EC_number="3.6.5.2"
                     /codon_start=1
                     /product="GTPase ERas"
                     /protein_id="NP_001102845.1"
                     /db_xref="GeneID:679682"
                     /db_xref="RGD:1585907"
                     /translation="MALPTKSSILDLSPGTQCSRSPEESHEAWAQCKDAGRQLPEYKA
                     VVVGASGVGKSALTIQMTHHCFVKDHDPTIQDSYWKEVALDNGGYILNVLDTAGQDSH
                     RALRDQCLAAGDGVLGVFALDDPSSLDQLQQICSTWNPHHKQPLVLVGNKSDLVSSAG
                     DAHTAAAVLAHKLGAPLVKTSAKTRQGVEEAFALLVHEIQRAQEAVAESSKKTRHHKA
                     VCSCGCSVA"
ORIGIN      
        1 caggggtcgg gcaggtggga gggggcaagc ccacatctcc gccccttgct gccgctgggg
       61 gtagggagca tcctaacccc caactgtccg gtcagatccg cctgctgccc ctcagccgac
      121 tgctactccg ggaacacagc acctgctgtt cacacctctt ccttgagctg cttgggaatg
      181 gccttgccaa caaagtctag catcttggac ctgagccccg gcacacagtg cagcagatcg
      241 ccagaggaga gccacgaggc ttgggcacaa tgcaaagatg ctggcaggca gctaccggag
      301 tacaaggcag tggtggtggg tgcgagcggt gtgggtaaaa gtgctctcac gatccagatg
      361 acccaccact gctttgtgaa agaccatgac cccactatcc aggattccta ctggaaggaa
      421 gtggccctgg acaacggagg ctacattcta aatgtgctag atacagctgg ccaggatagt
      481 caccgggccc tgcgtgacca gtgtttggca gctggtgatg gtgtgctggg tgtctttgct
      541 cttgatgacc cgtcgtctct ggaccaactg cagcagatat gctccacctg gaaccctcac
      601 cacaagcaac ctctggtact cgtgggcaac aagtctgacc tggtgagcag tgctggagac
      661 gcccacaccg ctgcagctgt ccttgctcac aagttgggag cccccttagt gaagacttcc
      721 gccaagacac ggcaaggtgt agaggaagct tttgctctgc tcgtccatga gattcagagg
      781 gcccaggagg ctgttgctga gtcaagcaag aagacccgac accacaaggc cgtgtgtagc
      841 tgtggctgct ctgtagcctg aagaccttag tctagcaaac tgacccgtct catgtcaagg
      901 tgacagttct ctcttgtcac gattcccctc cccgaccaat acctttttat tgccatttgg
      961 tgtgaggagt taggtggtaa catggggtgt cccttgttgg ctgtgttcag tgaaactcta
     1021 tgcaaaatta aataaatgtt ctcaggattc aaagcttcct ctatag
//
