LOCUS       NM_001108088            1662 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus epiphycan (Epyc), mRNA.
ACCESSION   NM_001108088 XM_001080536 XM_235083
VERSION     NM_001108088.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1662)
  AUTHORS   Hanada,Y., Nakamura,Y., Ishida,Y., Takimoto,Y., Taniguchi,M.,
            Ozono,Y., Koyama,Y., Morihana,T., Imai,T., Ota,Y., Sato,T.,
            Inohara,H. and Shimada,S.
  TITLE     Epiphycan is specifically expressed in cochlear supporting cells
            and is necessary for normal hearing
  JOURNAL   Biochem Biophys Res Commun 492 (3), 379-385 (2017)
   PUBMED   28864419
REFERENCE   2  (bases 1 to 1662)
  AUTHORS   Nuka,S., Zhou,W., Henry,S.P., Gendron,C.M., Schultz,J.B.,
            Shinomura,T., Johnson,J., Wang,Y., Keene,D.R., Ramirez-Solis,R.,
            Behringer,R.R., Young,M.F. and Hook,M.
  TITLE     Phenotypic characterization of epiphycan-deficient and
            epiphycan/biglycan double-deficient mice
  JOURNAL   Osteoarthritis Cartilage 18 (1), 88-96 (2010)
   PUBMED   19932218
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473960.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_235083.3, XM_001080536.1.
FEATURES             Location/Qualifiers
     source          1..1662
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..1662
                     /gene="Epyc"
                     /gene_synonym="Dspg3"
                     /note="epiphycan"
                     /db_xref="GeneID:314772"
                     /db_xref="RGD:1305904"
     exon            1..29
                     /gene="Epyc"
                     /gene_synonym="Dspg3"
                     /inference="alignment:Splign:2.1.0"
     CDS             21..1100
                     /gene="Epyc"
                     /gene_synonym="Dspg3"
                     /note="dermatan sulphate proteoglycan 3"
                     /codon_start=1
                     /product="epiphycan precursor"
                     /protein_id="NP_001101558.1"
                     /db_xref="GeneID:314772"
                     /db_xref="RGD:1305904"
                     /translation="MKHTRIHIHWSEVNTKDSVCSVTLCHFVKSEPKKSQKMRMAARI
                     VLVLIIIDATLAAPTTELFNYDSEVYDAILEDTGTFYNYEHIPDNQVETEKVAERLSG
                     NRELLTPGPQLGDSQDEDKDEESTPRLIDGSSPQEPEFPGLLGPHTNEDFPTCLLCTC
                     ISTTVYCDDHELDAIPPLPKKTTYFYSRFNRIKKINKNDFASLSDLKRIDLTSNLISE
                     IDEDAFRNLPRLQELVLRDNKIKQLPELPNTLTFIDISNNRLGRKGIKQEAFKDMYDL
                     HHLYITDNSLDHIPLPLPENLQALHLQNNDILEMHEDTFCNVKNLTYVRKALEDIRLD
                     GNPINLSKTPQAYMCLPRLPIGSFI"
     exon            30..119
                     /gene="Epyc"
                     /gene_synonym="Dspg3"
                     /inference="alignment:Splign:2.1.0"
     exon            120..296
                     /gene="Epyc"
                     /gene_synonym="Dspg3"
                     /inference="alignment:Splign:2.1.0"
     exon            297..471
                     /gene="Epyc"
                     /gene_synonym="Dspg3"
                     /inference="alignment:Splign:2.1.0"
     exon            472..630
                     /gene="Epyc"
                     /gene_synonym="Dspg3"
                     /inference="alignment:Splign:2.1.0"
     exon            631..833
                     /gene="Epyc"
                     /gene_synonym="Dspg3"
                     /inference="alignment:Splign:2.1.0"
     exon            834..929
                     /gene="Epyc"
                     /gene_synonym="Dspg3"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1662
                     /gene="Epyc"
                     /gene_synonym="Dspg3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtaatgtgcc accaagacaa atgaaacata ccagaattca tatccattgg tcagaggtaa
       61 ataccaagga ctctgtatgc tcagtcaccc tgtgccactt cgtcaagtcg gagccaaaga
      121 aatctcaaaa gatgagaatg gcagcaagaa ttgtcctggt acttatcatc attgatgcta
      181 cattggctgc accaaccaca gagctcttta actatgactc agaagtgtac gatgccatct
      241 tggaggacac ggggaccttt tataactatg aacacatacc tgacaaccaa gtagagactg
      301 agaaagtggc agagaggctt tctgggaaca gagagctcct cactccaggc ccacagctag
      361 gggacagtca ggatgaagac aaggatgaag aatctactcc cagactgatc gatggatctt
      421 ccccacagga gccagaattc ccaggacttc tgggtccaca caccaatgaa gactttccaa
      481 cctgcctcct gtgtacttgt ataagtacca ctgtatactg tgatgaccat gaacttgatg
      541 ccatccctcc gctgcccaag aagactacgt atttctattc acgcttcaac agaattaaaa
      601 agatcaacaa aaatgacttt gcaagtttaa gtgatttaaa aaggattgat ctgacatcca
      661 atttaatatc agagattgat gaagatgcat tccgaaatct gcctcgcctc caagagctgg
      721 tcctgcgaga caataagata aagcagcttc cagaattgcc aaacactttg acatttattg
      781 atatcagcaa caacagactc ggaaggaaag gcattaagca agaagcattt aaagacatgt
      841 atgatctcca ccatctctat ataacggata acagcttgga ccacattcct ctgccactcc
      901 cagaaaatct gcaggctctt cacctccaga ataatgacat tctggagatg catgaggaca
      961 ctttctgtaa cgttaaaaat ttaacttatg ttcgtaaggc gctagaggat attcgactgg
     1021 atggaaaccc gatcaacctc agcaaaactc ctcaggcata catgtgtcta cctcgtttgc
     1081 ccattggtag ttttatctaa tgttagaatg ttaggcaaac atcagcattg tgatgctttc
     1141 tgtagccaag tgaagcatat ctctcttcag aaacaaactc ggtatatttc cgatgtgtta
     1201 aaaaatgtgg catggttata taaacgataa ggtaagggtg ttaagataaa ataagaattc
     1261 aataacttaa ctaaacatga ttaagtataa attaacaaaa gatatagaca gtaaattagg
     1321 tatatatttg aactagtcat caaatctcat acaatttgaa aattgtagat gttcatgtca
     1381 agataaatat gtaagaaata aaacagttga aatgaatagt ttagaaacgt tgctaagatg
     1441 tagacatgta attaagtttc tttaacctta attatcactg atatatgttt cccacctgat
     1501 tcatttaaga gcacaaggaa agtattaaat gtgtttgaaa aatatgtggt cttgtgaaaa
     1561 agtgtttctt ataatcatag tttgcaagta actgtataca atagcaacac acattcattc
     1621 agtttcttga taaaatttat catttttaag accattaagt ca
//
