LOCUS       XM_006250425            4909 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus glutamyl-prolyl-tRNA synthetase 1
            (Eprs1), transcript variant X1, mRNA.
ACCESSION   XM_006250425
VERSION     XM_006250425.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051348.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006250425.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006250425.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4909
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4909
                     /gene="Eprs1"
                     /gene_synonym="Eprs"
                     /note="glutamyl-prolyl-tRNA synthetase 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 5 mRNAs, 121 ESTs, 15 long SRA reads, 2 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 133 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:289352"
                     /db_xref="RGD:1310952"
     CDS             156..4715
                     /gene="Eprs1"
                     /gene_synonym="Eprs"
                     /codon_start=1
                     /product="bifunctional glutamate/proline--tRNA ligase
                     isoform X1"
                     /protein_id="XP_006250487.1"
                     /db_xref="GeneID:289352"
                     /db_xref="RGD:1310952"
                     /translation="MAALCLTVNAGNPPLEALLAVEHVKGDVSISVEEGKENLLRVSE
                     SVVFTDTNSILRYLARVAATSGLYGSNLMEHTEIDHWLEFSATKLSSCDVLTSAIKEL
                     NHCLSLRTYLVGNSLTLADLCVWATLKGNAACQEHLRQSKTLVHVNRWYGFLEAQQAF
                     RSVGTKWDASANKATGAPDRKQDIGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAA
                     LLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETI
                     MKYAEKLIEEGKAYVDDTPADEMKAEREQRIESRHRKNPVEKNLQMWEEMKRGSQFGQ
                     SCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTH
                     ALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGW
                     DDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKLRALCKKVID
                     PVAPRYVALLKKEVIPVNILDAQEEMKEVARHPKNPDVGLKPVWYSPKVFIEGADAET
                     FSEGEMVTFINWGNINITKIHKNPDGKITSLDAKLNLENKDYKKTTKITWLAETTQAL
                     PVPAVCVTYEHLITKPVLGKDEDFKQYVNKDSKHEELMLGDPCLKDLKKGDIIQLQRR
                     GFFICDQPYEPVSPYSCKEAPCILIYIPDGHTKEMPTSGSKEKTKVEISKKETGSAPK
                     ERPAAAVSAPCAAAEDAAILYSRVAVQGDAVRDLKAKKAPKEDIDAAVKQLLTLKAEY
                     KEKTGQEYRPGNPPTAAVQTVSTKSPSNTGEYTSLYNKVAAQGELVRKLKAEKAPKAK
                     INDAVECLLSLKAEYKEKTGKEYVPGQLPASQNSHSSPVSNAKPVGSETPEAKLLFDR
                     VACQGEVVRKLKAEKASKDQVDSAVQELLQLKAQYKSLTGIEYKPVSATGAEDKDKKK
                     KEKENKSEKQNKPQKQNDGQGKDSSKSQGSGLSSGGAGEGQGPKKQTRLGLEAKKEEN
                     LAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDAEIKKLGVENCYFPIF
                     VSQGALEKEKNHIADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRD
                     LPIRLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATFEEAADEVLQILELYARVY
                     EELLAIPVVRGRKTEKEKFAGGDYTTTLEAFISASGRAIQGATSHHLGQNFSKMCEIV
                     FEDPKTPGEKQFAYQCSWGLTTRTIGVMIMVHGDNMGLVLPPRVASVQVVVIPCGITN
                     TLSEEDREALMAKCNEYRRRLLGADIRARVDLRDNYSPGWKFNHWELKGVPVRLEVGP
                     RDMKSCQFVAVRRDTGEKLTIAEKEAESKLKGVLEDIQLNLFTRASEDLKSHMVVSDT
                     LEDFQKVLDSGKVAQIPFCGEIDCEDWIKKTTARDQDVEPGAPSMGAKSLCIPFNPLC
                     ELQPGAMCVCGKNPAKFYTLFGRSY"
ORIGIN      
        1 gcaatgacac tagcggtcgc ggcctgtggg gtggagtcaa ggctgcggtg ccttcggtcg
       61 cgcgtacacg ttgcatctcc tagcttcctc ctgaaccccg ttttacgttc gcggcgggga
      121 aaacagcctg acgagtagac tgcagctcct gggagatggc ggcgctgtgc cttacggtga
      181 acgccggaaa ccctccactg gaagctctgc tggcagtgga gcatgtgaaa ggtgatgtca
      241 gcatttctgt ggaagaaggg aaggagaatc ttcttcgggt ttctgagagt gtggtgttca
      301 ctgacacaaa ttcaatcctg cgctacttgg ctagagttgc agctacatct gggctgtacg
      361 gttctaacct gatggagcac acggagattg atcattggtt ggagttcagc gctacaaagt
      421 tgtcttcgtg tgatgtgctg acttcggcaa tcaaggagct taaccattgc ctgtctctga
      481 gaacatacct ggttgggaac tctttgactt tagcagattt atgtgtttgg gccaccctaa
      541 aaggaaatgc tgcatgtcag gagcacttga gacagagcaa aaccctagtc cacgttaacc
      601 gctggtatgg ctttcttgaa gcccagcagg ccttccgttc agttggtacc aagtgggatg
      661 cttcagcaaa caaagctaca ggggcacctg acagaaaaca agatattggg aaattcgtcg
      721 agcttccggg tgcagagatg ggaaaggtga cagtcagatt ccccccagag gctagtggtt
      781 acttacacat tgggcatgca aaggctgctc ttctgaacca gcactaccag gttaacttta
      841 aaggcaaact gatcatgaga tttgatgaca caaacccaga aaaggaaaag gaagattttg
      901 agaaggtcat cttggaagat gttgcaatgc tgcacattaa accagatcag tttacttaca
      961 cttcagatca ttttgaaact ataatgaagt atgcagagaa attaattgaa gaagggaagg
     1021 cctatgtgga cgacactccc gcagacgaga tgaaggcgga gcgtgagcag aggatagagt
     1081 ccagacacag gaagaaccct gttgagaaga atctacaaat gtgggaagaa atgaaaagag
     1141 gaagccagtt tggtcagtcc tgttgcctgc gagcaaaaat tgacatgagt agtaacaatg
     1201 ggtgtatgag ggacccaacc ctttaccgct gcaaaatcca gccccaccca agaactggga
     1261 ataaatacaa tgtttaccca acgtatgact ttgcctgtcc tatagtggac agcattgaag
     1321 gtgttactca tgccttgagg acgacagagt accacgaccg agatgagcag ttttactgga
     1381 ttattgaagc cttaggcata aggaaaccat acatctggga atacagtcgc ttaaatctca
     1441 acaacacagt gctgtccaag agaaagctta cgtggtttgt caatgaagga ctggtagatg
     1501 gatgggatga ccctcggttt cctacagttc gtggagttct gaggagaggg atgacagttg
     1561 agggactgaa gcagttcatt gctgctcagg gctcctcaag gtctgttgta aacatggaat
     1621 gggacaaaat ctgggcgttt aacaaaaagc tgcgagctct ctgtaagaag gttattgacc
     1681 ctgtggctcc aaggtacgtt gcattgctga agaaggaggt gatcccagtg aacatcctgg
     1741 acgcgcagga ggagatgaag gaagtagcca gacatcccaa gaatcctgat gttggtttga
     1801 agcctgtgtg gtatagtccc aaggttttca tagaaggagc tgatgcagag actttctcag
     1861 agggtgaaat ggtcacattt ataaactggg gcaacatcaa cattactaaa atacacaaaa
     1921 atccagatgg aaaaattaca tctctggatg caaaattgaa tttggaaaac aaagactaca
     1981 agaaaacaac taagatcact tggcttgcgg agaccacaca ggctctccct gtcccggcag
     2041 tctgtgtcac ttatgagcac ttgattacaa agccagtgct aggaaaagac gaggacttca
     2101 agcagtacgt caacaaagac agtaagcatg aagaactaat gctaggagat ccctgcctta
     2161 aggatttgaa gaaaggagac atcatacaat tgcagaggcg cggattcttc atatgcgacc
     2221 agccgtacga acctgtcagc ccatatagtt gcaaagaagc cccctgcatc ttgatatata
     2281 tacccgatgg gcacaccaag gagatgccaa catctggatc aaaggaaaag actaaagtgg
     2341 aaatctcaaa aaaggagacc ggctctgctc ctaaggagag acccgcagct gctgtgagtg
     2401 ctccctgtgc tgcagctgag gacgctgcca tcctctacag cagagtggcg gtccagggtg
     2461 atgcggttcg cgacctgaaa gcgaagaaag caccaaagga ggatattgac gcagctgtga
     2521 aacagctttt gactttgaag gctgagtata aagagaaaac tgggcaggag tatagacctg
     2581 ggaacccccc tactgcagca gtgcagactg tttctacaaa gtccccatcc aacaccgggg
     2641 aatacacatc tttatacaat aaagttgctg cccaagggga gctggtccgg aagctgaaag
     2701 ctgaaaaggc tcctaaggct aaaataaatg atgctgtaga atgcttactg tccctgaaag
     2761 ctgagtataa agaaaaaact gggaaggagt atgtacctgg ccaactccca gcatctcaga
     2821 actcacattc aagtcctgtc agcaatgcca agcctgttgg atcagagaca ccggaagcca
     2881 aactgctgtt tgacagagtg gcttgtcaag gagaagtagt tcggaaactt aaagctgaga
     2941 aggcctctaa ggatcaagtg gattcagccg tacaagaact tcttcagctg aaggcacagt
     3001 acaagtcact gacaggaatt gagtataagc ctgtgtctgc tactggggca gaagacaaag
     3061 ataagaagaa gaaagaaaaa gaaaataagt ctgaaaagca gaataagcct cagaaacaaa
     3121 atgatggcca agggaaagac tcttctaaaa gccaaggcag cgggctgtcg tccggtggag
     3181 caggagaagg gcaagggccc aagaaacaga ccagattggg tcttgaagca aaaaaagaag
     3241 aaaatcttgc cgaatggtat tcccaagtca tcacgaagtc agagatgatc gaatactacg
     3301 atgtgagtgg ctgctatatt ctccgaccct ggtcgtactc catctgggaa tccattaagg
     3361 acttctttga cgcggagatc aagaagctcg gcgttgagaa ctgctacttc cccatattcg
     3421 tgtcccaggg cgcactagag aaggagaaga accacattgc tgactttgct cccgaggttg
     3481 cttgggtgac aagatctgga aagacagagc tggcagagcc gattgccatc cgtcctacta
     3541 gtgaaacagt aatgtatcct gcatatgcaa aatgggtgca gtcccacaga gacctgccca
     3601 tcaggctcaa ccagtggtgc aacgtggtgc gctgggagtt caaacaccca caacctttcc
     3661 tccgcactcg ggagttccta tggcaggagg ggcacagcgc ctttgccacc tttgaggagg
     3721 cagctgacga ggtgttacag atcctcgagt tatatgctcg agtgtatgag gagctcttgg
     3781 caatccccgt cgtgagagga aggaagactg agaaggaaaa gtttgcagga ggagactata
     3841 caaccacact agaagccttc atatctgcca gcggacgcgc tatccaggga gcaacatcac
     3901 accatttagg ccagaatttc tccaaaatgt gtgaaatagt ttttgaagat cccaagacac
     3961 caggagaaaa gcagtttgca taccagtgct cctggggcct gacaactcgc actatcggtg
     4021 tgatgatcat ggtccatggg gacaacatgg gcttagtgtt acctccccgt gtagcgtctg
     4081 tccaggtggt agtcattccc tgtggaatca cgaatacctt gtctgaagaa gacagagagg
     4141 ccctgatggc aaaatgcaat gagtacagga gacggctgct cggcgctgac atccgagctc
     4201 gagtcgatct acgagacaac tactcaccag gctggaagtt caaccactgg gagctcaagg
     4261 gtgttccagt cagacttgag gtggggccac gtgatatgaa gagctgtcag tttgtagcag
     4321 tcagacgaga tactggagag aagctgacaa ttgctgaaaa ggaggcggag tctaaactga
     4381 aaggggtttt ggaagacatc cagcttaacc ttttcacaag ggcttctgaa gaccttaaat
     4441 ctcacatggt tgtatcggat acactggaag actttcagaa ggtgctagat tctgggaagg
     4501 ttgcacagat tccattctgt ggggaaattg actgtgagga ctggatcaaa aagacaacgg
     4561 ccagggatca ggatgtggaa cctggtgctc catccatggg agccaaaagc ctttgcattc
     4621 ctttcaaccc tctgtgtgag ctgcagccag gagccatgtg tgtctgtggc aagaatcctg
     4681 ccaagttcta caccttgttt ggtcggagtt actgatggat gaaacagaag cctctcccgt
     4741 ccttttttta aaaccaatga tactaagatc tcagatacag tttttctttt tcatttttta
     4801 aaacttctaa aaaggtcaca aaataaacag ctattcttat gcccaaatta acagtggaaa
     4861 atacttttct gtaaacagcc agggtaataa aaaccatgaa ctaattgta
//
