LOCUS       NM_134331               6863 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus Eph receptor A7 (Epha7), mRNA.
ACCESSION   NM_134331
VERSION     NM_134331.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6863)
  AUTHORS   Li,S., Zhai,J., Xu,B., Liu,J., Chu,W., Wang,D., Geng,X., Chen,Z.J.
            and Du,Y.
  TITLE     Erythropoietin-producing hepatocellular receptor A7 restrains
            estrogen negative feedback of luteinizing hormone via ephrin A5 in
            the hypothalamus of female rats
  JOURNAL   Am J Physiol Endocrinol Metab 319 (1), E81-E90 (2020)
   PUBMED   32396496
  REMARK    GeneRIF: Erythropoietin-producing hepatocellular receptor A7
            restrains estrogen negative feedback of luteinizing hormone via
            ephrin A5 in the hypothalamus of female rats.
REFERENCE   2  (bases 1 to 6863)
  AUTHORS   Li,S., Zhai,J., Liu,J., Di,F., Sun,Y., Li,W., Chen,Z.J. and Du,Y.
  TITLE     Erythropoietin-producing hepatocellular A7 triggering ovulation
            indicates a potential beneficial role for polycystic ovary syndrome
  JOURNAL   EBioMedicine 36, 539-552 (2018)
   PUBMED   30292674
  REMARK    GeneRIF: EPHA7 is a positive upstream factor of C/EBPbeta
            contributing to the transcription and translation of KLF4,
            promoting ovulation via ADAMTS1. We demonstrated the functional
            role of EPHA7 in PCOS, which explains how the loss of EPHA7
            underlies the ovulatory dysfunction.
REFERENCE   3  (bases 1 to 6863)
  AUTHORS   Amegandjin,C.A., Jammow,W., Laforest,S., Riad,M., Baharnoori,M.,
            Badeaux,F., DesGroseillers,L., Murai,K.K., Pasquale,E.B., Drolet,G.
            and Doucet,G.
  TITLE     Regional expression and ultrastructural localization of EphA7 in
            the hippocampus and cerebellum of adult rat
  JOURNAL   J Comp Neurol 524 (12), 2462-2478 (2016)
   PUBMED   26780036
  REMARK    GeneRIF: The cell surface localization of EphA7 was preferentially
            in postsynaptic dendrites in the hippocampus and cerebellum.
REFERENCE   4  (bases 1 to 6863)
  AUTHORS   Beuter,S., Ardi,Z., Horovitz,O., Wuchter,J., Keller,S., Saha,R.,
            Tripathi,K., Anunu,R., Kehat,O., Kriebel,M., Richter-Levin,G. and
            Volkmer,H.
  TITLE     Receptor tyrosine kinase EphA7 is required for interneuron
            connectivity at specific subcellular compartments of granule cells
  JOURNAL   Sci Rep 6, 29710 (2016)
   PUBMED   27405707
  REMARK    GeneRIF: EphA7 regulates gephyrin clustering and the maintenance of
            inhibitory synaptic connectivity via mTOR signaling.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6863)
  AUTHORS   Weiss,A.C., Airik,R., Bohnenpoll,T., Greulich,F., Foik,A.,
            Trowe,M.O., Rudat,C., Costantini,F., Adams,R.H. and Kispert,A.
  TITLE     Nephric duct insertion requires EphA4/EphA7 signaling from the
            pericloacal mesenchyme
  JOURNAL   Development 141 (17), 3420-3430 (2014)
   PUBMED   25139858
REFERENCE   6  (bases 1 to 6863)
  AUTHORS   Matsunaga,T., Greene,M.I. and Davis,J.G.
  TITLE     Distinct expression patterns of eph receptors and ephrins relate to
            the structural organization of the adult rat peripheral vestibular
            system
  JOURNAL   Eur J Neurosci 12 (5), 1599-1616 (2000)
   PUBMED   10792438
REFERENCE   7  (bases 1 to 6863)
  AUTHORS   Janis,L.S., Cassidy,R.M. and Kromer,L.F.
  TITLE     Ephrin-A binding and EphA receptor expression delineate the matrix
            compartment of the striatum
  JOURNAL   J Neurosci 19 (12), 4962-4971 (1999)
   PUBMED   10366629
REFERENCE   8  (bases 1 to 6863)
  AUTHORS   Buchert,M., Schneider,S., Meskenaite,V., Adams,M.T., Canaani,E.,
            Baechi,T., Moelling,K. and Hovens,C.M.
  TITLE     The junction-associated protein AF-6 interacts and clusters with
            specific Eph receptor tyrosine kinases at specialized sites of
            cell-cell contact in the brain
  JOURNAL   J Cell Biol 144 (2), 361-371 (1999)
   PUBMED   9922461
REFERENCE   9  (bases 1 to 6863)
  AUTHORS   Torres,R., Firestein,B.L., Dong,H., Staudinger,J., Olson,E.N.,
            Huganir,R.L., Bredt,D.S., Gale,N.W. and Yancopoulos,G.D.
  TITLE     PDZ proteins bind, cluster, and synaptically colocalize with Eph
            receptors and their ephrin ligands
  JOURNAL   Neuron 21 (6), 1453-1463 (1998)
   PUBMED   9883737
REFERENCE   10 (bases 1 to 6863)
  AUTHORS   Valenzuela,D.M., Rojas,E., Griffiths,J.A., Compton,D.L., Gisser,M.,
            Ip,N.Y., Goldfarb,M. and Yancopoulos,G.D.
  TITLE     Identification of full-length and truncated forms of Ehk-3, a novel
            member of the Eph receptor tyrosine kinase family
  JOURNAL   Oncogene 10 (8), 1573-1580 (1995)
   PUBMED   7731712
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Jun 3, 2021 this sequence version replaced NM_134331.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.22207.1, U21954.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-314               JAXUCZ010000005.1  47771893-47772206
            315-379             JAXUCZ010000005.1  47776125-47776189
            380-1049            JAXUCZ010000005.1  47779661-47780330
            1050-1205           JAXUCZ010000005.1  47830563-47830718
            1206-1541           JAXUCZ010000005.1  47831472-47831807
            1542-1666           JAXUCZ010000005.1  47894466-47894590
            1667-1850           JAXUCZ010000005.1  47897201-47897384
            1851-1959           JAXUCZ010000005.1  47901363-47901471
            1960-2015           JAXUCZ010000005.1  47902078-47902133
            2016-2141           JAXUCZ010000005.1  47906278-47906403
            2142-2327           JAXUCZ010000005.1  47907313-47907498
            2328-2389           JAXUCZ010000005.1  47908037-47908098
            2390-2599           JAXUCZ010000005.1  47909305-47909514
            2600-2749           JAXUCZ010000005.1  47910213-47910362
            2750-2943           JAXUCZ010000005.1  47918732-47918925
            2944-3099           JAXUCZ010000005.1  47919875-47920030
            3100-6863           JAXUCZ010000005.1  47921426-47925189
FEATURES             Location/Qualifiers
     source          1..6863
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q21"
     gene            1..6863
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /note="Eph receptor A7"
                     /db_xref="GeneID:171287"
                     /db_xref="RGD:70957"
     exon            1..314
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     CDS             218..3214
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /EC_number="2.7.10.1"
                     /note="ephrin receptor EphA7; ephrin type-A receptor 7;
                     EPH homology kinase 3; tyrosine-protein kinase receptor
                     EHK-3"
                     /codon_start=1
                     /product="ephrin type-A receptor 7 precursor"
                     /protein_id="NP_599158.1"
                     /db_xref="GeneID:171287"
                     /db_xref="RGD:70957"
                     /translation="MVVQTRYPSWIILCYIWLLGFAHTGEAQAAKEVLLLDSKAQQTE
                     LEWISSPPSGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVEL
                     KFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDL
                     GERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSIIENLAVFPDT
                     VTGSEFSSLVEVRGTCVSSAEEEAENSPRMHCSAEGEWLVPIGKCICKAGYQQKGDTC
                     EPCGRRFYKSSSQDLQCSRCPTHSFSDREGSSRCECEDGYYRAPSDPPYVACTRPPSA
                     PQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMPQQ
                     TGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGVM
                     KERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTLKTKSTSASINNLKPG
                     TVYVFQIRAFTAAGYGNYSPRLDVATLEEASGKMFEATAVSSEQNPVIIIAVVAVAGT
                     IILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPGTKTYIDPETYEDPNRAVHQF
                     AKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCE
                     ASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLR
                     GIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKI
                     PVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLP
                     APMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPSSLKTPLGTCSRPISPL
                     LDQSTPDFTAFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIDDVMSLGITLVG
                     HQKKIMSSIQTMRAQMLHLHGTGIQV"
     exon            315..379
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     exon            380..1049
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1205
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1206..1541
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1542..1666
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1667..1850
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1851..1959
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1960..2015
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     exon            2016..2141
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     exon            2142..2327
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     exon            2328..2389
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     exon            2390..2599
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     exon            2600..2749
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     exon            2750..2943
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     exon            2944..3099
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
     exon            3100..6863
                     /gene="Epha7"
                     /gene_synonym="EHK-3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtctgcagt cggagacttg caggcagcaa acacggtgcg aacgaaccgg aggggggaaa
       61 gagaaatcaa acgaggagca gccggcctgg gacccagaaa gggatcgatg agaggagcgc
      121 aataataaca ataataaccc acttcggagc aaacagcatc taaagagctg cgacccaact
      181 gcagcctaaa aaaaaaaatc aaacctgctc atgcaccatg gttgttcaaa ctcggtaccc
      241 ttcgtggatt attttgtgtt acatctggct gcttggcttt gcacacacgg gggaggcgca
      301 ggctgcgaag gaagtactgt tactggactc gaaagcacaa caaacagaat tggaatggat
      361 ttcctctcca cccagtgggt gggaagaaat tagtggtttg gatgagaact acacaccaat
      421 aagaacatac caggtgtgcc aggtcatgga gcccaaccag aacaactggc ttcggactaa
      481 ctggatttct aaaggcaacg cacaaaggat ttttgtagaa ttgaaattca ccttgaggga
      541 ttgtaatagt cttcccggag tcctgggaac ttgcaaggaa acctttaatt tgtactatta
      601 tgaaacagac tacgacaccg gcaggaatat acgagaaaac ctttacgtta aaatagacac
      661 cattgctgca gatgaaagtt ttacacaagg tgaccttggt gaaagaaaga tgaagctgaa
      721 cactgaggtg agagagattg gacctttgtc caaaaaggga ttctatcttg cctttcagga
      781 tgtaggggct tgcatagcat tggtttctgt caaagtatac tacaagaagt gctggtccat
      841 tattgagaac ttagctgtct ttccagatac agtgactggt tcagaatttt cctccttagt
      901 tgaggtccgt gggacatgtg tcagcagtgc cgaggaagag gcagaaaatt cacccaggat
      961 gcattgcagt gcagaaggag agtggttagt acccattgga aaatgtatct gcaaagcagg
     1021 ctatcagcaa aaaggggaca cttgtgaacc ctgtggccgc aggttctaca aatcttcctc
     1081 tcaggacctt cagtgttctc gttgtccaac ccacagtttc tctgaccgag aaggatcatc
     1141 gaggtgtgaa tgtgaagacg ggtactacag agctccttct gacccaccat acgtcgcatg
     1201 cacgaggcct ccctctgcac cacagaacct tattttcaac atcaatcaaa cgactgtaag
     1261 tttggagtgg agtcctccag ctgacaacgg aggaagaaac gatgtcacct acagaatatt
     1321 gtgtaagcgg tgcagctggg agcagggaga atgtgtacca tgcggaagta acattggata
     1381 catgccccag cagacgggat tagaggataa ctatgtcact gtcatggacc tgcttgccca
     1441 tgcaaattac acgttcgaag ttgaagctgt aaatggagtt tcagacttaa gcagatccca
     1501 gaggcttttt gcagccgtta gcatcaccac tggtcaagca gctccctcgc aagtgagcgg
     1561 agtgatgaag gagagagtgc tgcagcggag tgtggagctt tcctggcagg aaccagaaca
     1621 tcccaacgga gtcatcacgg aatatgaaat caagtattat gagaaagatc aaagagaaag
     1681 gacgtactca acactgaaaa ccaagtccac ctcagcctcc attaataatc tgaaaccggg
     1741 aacagtgtat gtttttcaga tccgggcgtt cactgctgcc ggctatggaa attacagccc
     1801 taggctggat gttgcaacac tagaggaagc ttcaggtaaa atgtttgaag caacagcggt
     1861 gtccagtgaa cagaatcccg tcatcataat tgctgtggtg gctgtagcag ggaccatcat
     1921 cttggtgttc atggtgttcg gcttcatcat tggaagaagg cactgtggtt acagcaaggc
     1981 tgaccaagaa ggggatgaag aactctactt tcattttaaa tttccaggca ccaaaaccta
     2041 cattgaccct gaaacctatg aggacccaaa tagagctgtc catcaattcg ccaaggagct
     2101 agatgcctcc tgtattaaaa ttgagcgtgt gattggtgca ggagaatttg gagaagtttg
     2161 cagtggtcgt ttgaaacttc cagggaaaag agatgttgca gtggctataa aaaccctgaa
     2221 agttggttac acagaaaaac aaaggaggga ctttttatgc gaagcaagca tcatggggca
     2281 atttgaccac ccaaatgtcg tccatttgga aggggttgtt acaagaggga agcctgtcat
     2341 gatcgtgata gagttcatgg agaacggcgc cctggatgca tttctcagga aacatgatgg
     2401 gcaatttaca gtcattcagt tggtaggaat gctgagagga attgcggctg gcatgcgcta
     2461 cttggctgac atgggatacg ttcacaggga ccttgcggct cgcaacattc ttgtgaacag
     2521 caatcttgtt tgtaaagtgt ccgattttgg cctgtcccgg gttatagagg atgaccccga
     2581 agctgtctac acgactactg gtggaaaaat tccagtaagg tggactgccc ctgaagccat
     2641 ccaataccgg aaattcacct cagccagtga tgtgtggagc tatgggattg tcatgtggga
     2701 agtaatgtct tatggagaac gaccttattg ggacatgtcg aatcaagatg tcattaaagc
     2761 gatagaagaa ggttatcgct taccagcacc catggactgc ccagctggtc ttcaccagct
     2821 aatgctggat tgttggcaga aagaacgggc agagaggcca aagtttgagc agatagtcgg
     2881 aattctagac aaaatgattc gaaatccaag cagtctgaaa acacccctgg gaacttgtag
     2941 cagacccata agccctcttc tggaccagag cactcccgac ttcactgcct tctgttcagt
     3001 gggagagtgg ttgcaggcta ttaaaatgga gaggtataaa gacaacttca cagcggcagg
     3061 ttacaactca ctcgagtcgg tggcccggat gaccatcgac gatgtgatga gtttagggat
     3121 cacactggtt ggccatcaaa agaagattat gagcagcatc cagactatgc gggcacagat
     3181 gctgcactta cacggaaccg gcatccaagt gtgacacatc cgcctccctc agtgaggctt
     3241 aagactgcaa gagaacagtt ccggccttca gtatacacat agaatgctgc tagaagacag
     3301 tttgatatac tgggtccttc ctacaataaa gagaagattt tagaagcacc tacagacttg
     3361 aactcctaag tgccaccaga atatacaaaa agggaattta ggatccacca ctggtggcca
     3421 ggaacacagc agagacaata aacaaagtac tacctgaaaa aaacatccca acaccttgag
     3481 ctctcgaacc tcctttttat cttatagact ttttaaaatg tacataaaga atttaagaaa
     3541 gaatatattt gtcaaataaa atcatgatct tattgttaaa aaaatcaatg aaatattttc
     3601 cttaaaatat gtgatttcag actattcttt ttccagaacc atctgtgttg attctgcata
     3661 aggactttgt tttagaaagt tatttgtagc tttggacctt tttagcgtta aatttacgac
     3721 acgtaactac actgggtacc tttgagggaa tctcaaactt aaaggaaaac aaaactacgg
     3781 cacatcgttg aggatatgac tttgtccttc ctggctttgg tatcctggct gtgtcatttt
     3841 gttctgttaa accagtgatg ttttgttatt gtttgcgaat tggcaggtag ttcagaattg
     3901 caagttgcca agagcgctga tattttttaa cgggaatttt tttttctttg taaaaatcag
     3961 acaacatact aacttttcaa tgaaaaagac aaagcaataa tgatccataa atactataag
     4021 gcacttttaa cagattgttt atagagtgat ttactaggca gaatttaata aaaaaaatgt
     4081 caaattttag gtttatgtgt atatgataaa aaggctgagg ctttatctga agaggctggt
     4141 gaaagtgttt ctggaggcag aagctctcca gcgttggctc accccgtcgg agcacatcaa
     4201 gagtttcagt cttgtgacag taagaaattt aggaacatag ttgacctata ttttgtattc
     4261 tttcttgttg aatgcagtcc aaatacaaaa gtaacgaatt cagttttcta ctgttactct
     4321 gaagcaagat cacagggggc agttcacttc tcaccactca cagactaatg tgcagcaaat
     4381 acttctacca ctgcagtgag aagaaagcaa aacagaggta ttttatctat gaacagtcac
     4441 acacacacac acacacacac acacacacac acacacacac acaccccttt taggtcaaaa
     4501 ttcatttacc ccagaaggaa gaagtaaagg gtctggcttt tctgtttcca ctttatttat
     4561 cagaccatat tatttggtta ctgtgttaga atttcataag caataattaa atgtgtcttt
     4621 ataggtattt caggaatgta tacatatttg agtaatgttt ttcaaaagtt agaaaaatca
     4681 tgaactaccc caaaaccgaa ctgttgtact tccaaagaaa attgggctgt ttataacaat
     4741 tttactagag aaagatccca gggatcggtc ctaattggtg ttgtttggta atgtgggcct
     4801 ccacaaacaa acaaacaaaa acaggtaaca cgcgaaatct gtaaatgttc ctttgtaaaa
     4861 cttgtaaatt ttatttatac cgtcttgttt tgtatacaca tttctcagta gtggctccaa
     4921 gtacatgaaa atgcactata tttttctatt ttacttgcag agcttctcaa agaaacaggt
     4981 attttcagtg ctacataatg tgtttttccc acatttagga ccaaagatgg ctatagaaaa
     5041 ctcaaatgga ttgcttccca aacccctccc tatccatttt tgtttttttt tcttttacca
     5101 ctgtacagtg ttatttgata ttttaattta ttttttttga ttgaatagaa aactcatttt
     5161 aatttctcta aaaatgtttt tgtccctaag gaaaacaaaa atctgtaaaa ataattttaa
     5221 ttagcgtaat ccagtcaccc tagacacttc catttgtaat ctttgtaata gactgtaaat
     5281 atatttttgg aactataaca caatgtgctt gagggttatt tttcagtgtg tgcagtgtat
     5341 acaaaagtgt ttatactcag tacagcactt tacaattcta atcagtagcg ttggcctttg
     5401 tgcgaatgag tgcgagcttg agcgagtgtt ctctaattcc gtttggattc tggactcact
     5461 aataatgaag ttcttttctt gttcatagct taaggtgctt attttttcta ttaaaaatta
     5521 aattaacaaa aaagccattc tagaaataga agacgcagta tggtacatgc agacagagtc
     5581 tttcctgctt tttctagtaa tagatttata gttgagtagt ctttcttgag tagaagggca
     5641 gaataaaagt gttttgtttt gttttatttt gtttttaatt ttcttttcaa aaataacttt
     5701 ttccttcagc aatatacctc atctgcctta aattttttac agctctttac agggaaaggg
     5761 gagaagggat gggaaagaca cagcacaata ggaagtggat gattgcatcg tgctctctct
     5821 tttgtaggtt tctttttcta atcaacacta tgatttttga agtacgcgaa cgtgaagcaa
     5881 acatggagag atgaggaatt agcattgtga acctgattgt aatcctctct tccagtaaga
     5941 gatgagacgc tattgcagtg agaatgtaca acttgcttgc accttgaaat cttttttgat
     6001 aattagtgct cagggggagg gaagtagaga aagcaaacgc ccaacagaga attccaaaag
     6061 gacagaacac acaacaggaa gttgcctcct tgctttaatg tagccacctt ttttttatag
     6121 aacaccgccc acccacacca cctggtttgc attcagttct gaaatactta caagtaactt
     6181 gttgcattga gaacgagtct tttctcagca atggatcagg gcctcgtttt ctagactggt
     6241 ggctcatgct tctcagagca ctattggttg aatcatattg tatacttatg taatctacat
     6301 tagctagtac tctttaggac tatattttaa ttgctcctct tcttggtgtt tttaagacaa
     6361 tggaaagggt gtaagtcacc tctcttttat ttaggtaatg ctgatccctc cccttttgtt
     6421 tcctgagcag cccaaaactg tactgctccc ctatgtgcat gttccaatga attactgatg
     6481 tgtatttttt tttccttttt ttgctatatg tggagaaatc atggggaact cggggcgaaa
     6541 tatgcttttt gttggttgaa ttttgtccct ccttgcctaa gaattactac aggggtcatc
     6601 cttttataag gacaaaaata tgcttttgaa cagtgtcttc aatgtatcaa gcacaaataa
     6661 ctctttcttc aacacgaatc ataagtctct ttttaccagc ttaaaataat aaacaagtct
     6721 attagacaat gtaaagaaaa tcctgtctcc agtcattggt gggctccttc acattcctta
     6781 tgctttcctt tcctacctaa gaagattttg tgaaaatagt tctgcggggc tgatcagaat
     6841 atgaataaaa ctgattattc cta
//
