LOCUS       NM_001162411            6338 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus Eph receptor A4 (Epha4), mRNA.
ACCESSION   NM_001162411 XM_244186 XR_007714
VERSION     NM_001162411.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6338)
  AUTHORS   Zhao,L., Wang,Z., Chen,H., Du,Y., Ma,W., Tao,Q., Ma,X., Wu,Z. and
            Peng,J.
  TITLE     Effects of lncRNA HOXA11-AS on Sevoflurane-Induced Neuronal
            Apoptosis and Inflammatory Responses by Regulating miR-98-5p/EphA4
  JOURNAL   Mediators Inflamm 2023, 7750134 (2023)
   PUBMED   37064501
  REMARK    GeneRIF: Effects of lncRNA HOXA11-AS on Sevoflurane-Induced
            Neuronal Apoptosis and Inflammatory Responses by Regulating
            miR-98-5p/EphA4.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6338)
  AUTHORS   Zhou,Z.X., Xu,L.J., Wang,H.N., Cheng,S., Li,F., Miao,Y., Lei,B.,
            Gao,F. and Wang,Z.
  TITLE     EphA4/ephrinA3 reverse signaling mediated downregulation of
            glutamate transporter GLAST in Muller cells in an experimental
            glaucoma model
  JOURNAL   Glia 71 (3), 720-741 (2023)
   PUBMED   36416239
  REMARK    GeneRIF: EphA4/ephrinA3 reverse signaling mediated downregulation
            of glutamate transporter GLAST in Muller cells in an experimental
            glaucoma model.
REFERENCE   3  (bases 1 to 6338)
  AUTHORS   Li,J., Dong,W., Gao,X., Chen,W., Sun,C., Li,J., Gao,S., Zhang,Y.,
            He,J., Lu,D., Jiang,R., Ma,M., Wang,X. and Zhang,L.
  TITLE     EphA4 is highly expressed in the atria of heart and its deletion
            leads to atrial hypertrophy and electrocardiographic abnormalities
            in rats
  JOURNAL   Life Sci 278, 119595 (2021)
   PUBMED   33974931
  REMARK    GeneRIF: EphA4 is highly expressed in the atria of heart and its
            deletion leads to atrial hypertrophy and electrocardiographic
            abnormalities in rats.
REFERENCE   4  (bases 1 to 6338)
  AUTHORS   Wang,J.L., Chen,W.G., Zhang,J.J. and Xu,C.J.
  TITLE     Nogo-A-Delta20/EphA4 interaction antagonizes apoptosis of neural
            stem cells by integrating p38 and JNK MAPK signaling
  JOURNAL   J Mol Histol 52 (3), 521-537 (2021)
   PUBMED   33555537
  REMARK    GeneRIF: Nogo-A-Delta20/EphA4 interaction antagonizes apoptosis of
            neural stem cells by integrating p38 and JNK MAPK signaling.
REFERENCE   5  (bases 1 to 6338)
  AUTHORS   Li,J., Ma,N., Chen,J., Yan,D., Zhang,Q. and Shi,J.
  TITLE     EphA4 receptor regulates outwardly rectifying chloride channel in
            CA1 hippocampal neurons after ischemia-reperfusion
  JOURNAL   Neuroreport 30 (14), 980-984 (2019)
   PUBMED   31469726
  REMARK    GeneRIF: n the present study, we demonstrated that EphA4 receptor
            potentiated the activity of outwardly rectifying chloride channel
            in rat hippocampal neurons after ischemia-reperfusion
REFERENCE   6  (bases 1 to 6338)
  AUTHORS   Lai,K.O., Ip,F.C., Cheung,J., Fu,A.K. and Ip,N.Y.
  TITLE     Expression of Eph receptors in skeletal muscle and their
            localization at the neuromuscular junction
  JOURNAL   Mol Cell Neurosci 17 (6), 1034-1047 (2001)
   PUBMED   11414792
REFERENCE   7  (bases 1 to 6338)
  AUTHORS   Ito,M., Yoshioka,K., Akechi,M., Yamashita,S., Takamatsu,N.,
            Sugiyama,K., Hibi,M., Nakabeppu,Y., Shiba,T. and Yamamoto,K.I.
  TITLE     JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein
            that functions as a Scaffold factor in the JNK signaling pathway
  JOURNAL   Mol Cell Biol 19 (11), 7539-7548 (1999)
   PUBMED   10523642
REFERENCE   8  (bases 1 to 6338)
  AUTHORS   Janis,L.S., Cassidy,R.M. and Kromer,L.F.
  TITLE     Ephrin-A binding and EphA receptor expression delineate the matrix
            compartment of the striatum
  JOURNAL   J Neurosci 19 (12), 4962-4971 (1999)
   PUBMED   10366629
REFERENCE   9  (bases 1 to 6338)
  AUTHORS   Moreno-Flores,M.T. and Wandosell,F.
  TITLE     Up-regulation of Eph tyrosine kinase receptors after excitotoxic
            injury in adult hippocampus
  JOURNAL   Neuroscience 91 (1), 193-201 (1999)
   PUBMED   10336070
REFERENCE   10 (bases 1 to 6338)
  AUTHORS   Dottori,M., Hartley,L., Galea,M., Paxinos,G., Polizzotto,M.,
            Kilpatrick,T., Bartlett,P.F., Murphy,M., Kontgen,F. and Boyd,A.W.
  TITLE     EphA4 (Sek1) receptor tyrosine kinase is required for the
            development of the corticospinal tract
  JOURNAL   Proc Natl Acad Sci U S A 95 (22), 13248-13253 (1998)
   PUBMED   9789074
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On or before Jun 24, 2009 this sequence version replaced
            XR_007714.1, XM_244186.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.1256565.1,
                                           SRR26360176.348958.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            NMD candidate          :: translation inferred from conservation
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-147               JAXUCZ010000009.1  86406551-86406697   c
            148-215             JAXUCZ010000009.1  86403336-86403403   c
            216-879             JAXUCZ010000009.1  86398179-86398842   c
            880-1035            JAXUCZ010000009.1  86340457-86340612   c
            1036-1374           JAXUCZ010000009.1  86322195-86322533   c
            1375-1499           JAXUCZ010000009.1  86297521-86297645   c
            1500-1659           JAXUCZ010000009.1  86296158-86296317   c
            1660-1771           JAXUCZ010000009.1  86295009-86295120   c
            1772-1830           JAXUCZ010000009.1  86286445-86286503   c
            1831-1944           JAXUCZ010000009.1  86284884-86284997   c
            1945-2130           JAXUCZ010000009.1  86284192-86284377   c
            2131-2192           JAXUCZ010000009.1  86279998-86280059   c
            2193-2402           JAXUCZ010000009.1  86279342-86279551   c
            2403-2552           JAXUCZ010000009.1  86277324-86277473   c
            2553-2746           JAXUCZ010000009.1  86273976-86274169   c
            2747-2902           JAXUCZ010000009.1  86271410-86271565   c
            2903-3853           JAXUCZ010000009.1  86269628-86270578   c
            3854-6338           JAXUCZ010000009.1  86263982-86266466   c
FEATURES             Location/Qualifiers
     source          1..6338
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q33"
     gene            1..6338
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /note="Eph receptor A4"
                     /db_xref="GeneID:316539"
                     /db_xref="RGD:1560587"
     exon            1..147
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..3017
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /EC_number="2.7.10.1"
                     /note="ephrin type-A receptor 4"
                     /codon_start=1
                     /product="ephrin type-A receptor 4 precursor"
                     /protein_id="NP_001155883.1"
                     /db_xref="GeneID:316539"
                     /db_xref="RGD:1560587"
                     /translation="MAGIFYFILFSFLFGICDAVTGSRVYPANEVTLLDSRSVQGELG
                     WIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEASQNNWLRTDWITREGAQRVYIEIK
                     FTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRESQFGKIDTIAADESFTQVDIG
                     DRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTI
                     TGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEEQNGECQAC
                     KIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLN
                     LISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNG
                     LKTTRVSITDLLAHTNYTFEIWAVNGVSKYNPSPDQSVSVTVTTNQAAPSSIALVQAK
                     EVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPLTS
                     YVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAA
                     FVISRRRSKYSQAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIE
                     KVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNI
                     IHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDM
                     SYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAY
                     RKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQL
                     MLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGPESSRPNTALLDPSSPEFSAVV
                     SVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHMSQDDLARIGITAITHQNKILSSVQAM
                     RTQMQQMHGRMVPV"
     exon            148..215
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            216..879
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            880..1035
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..1374
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            1375..1499
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            1500..1659
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            1660..1771
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            1772..1830
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            1831..1944
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            1945..2130
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            2131..2192
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            2193..2402
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            2403..2552
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            2553..2746
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            2747..2902
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            2903..3853
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
     exon            3854..6338
                     /gene="Epha4"
                     /gene_synonym="RGD1560587"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagcatttat tccactggga tagaagcggt aggagcagcg ttggcaccgg cgaaccatgg
       61 ctgggatttt ctatttcatc ctcttttcgt ttctctttgg aatttgcgac gctgtcaccg
      121 gttctagggt atacccggcg aatgaagtta ctttattgga ttccagatct gttcagggag
      181 agcttgggtg gatagcaagc cctctggaag gagggtggga ggaagtaagc attatggatg
      241 agaaaaatac accgatccga acctaccagg tatgcaacgt gatggaagcc agtcagaaca
      301 actggctgcg aactgactgg atcacccgag aaggggcgca gagggtgtac attgaaatta
      361 agttcactct gagggactgc aacagtcttc cgggcgtcat ggggacttgc aaggagacgt
      421 ttaaccttta ctactatgaa tcggacaacg acaaggagcg cttcatcaga gagagccagt
      481 tcggcaagat cgacaccatc gcagcggatg agagctttac acaggtggac attggggaca
      541 gaatcatgaa gctcaacacc gagatccggg atgtagggcc cctgagcaag aagggttttt
      601 acctggcttt tcaggatgtg ggtgcttgca tcgccctggt gtctgttcgt gtgttctaca
      661 agaagtgtcc cctcaccgtt cgaaatctag cccagttccc cgataccatc actggggctg
      721 atacctcttc cctggtggaa gttcgaggct cctgtgtcaa caactcagaa gagaaggatg
      781 tgccaaaaat gtactgtggg gcagatggtg aatggctggt acccattggc aactgcctat
      841 gcaatgctgg gcacgaggag cagaatggtg aatgccaagc ttgcaaaatt ggatattaca
      901 aagctctctc cacggacgcc acctgtgcca agtgtccacc gcacagctac tctgtctggg
      961 aaggagccac gtcctgcacc tgtgaccgag gctttttcag agctgacaac gatgccgcgt
     1021 ccatgccctg cacccgccca ccatctgctc ccctcaactt gatttctaat gtcaacgaga
     1081 cgtcggtgaa cttggaatgg agcagtcctc agaacacagg tggccgtcag gacatttctt
     1141 acaacgtggt ctgcaagaaa tgtggagctg gggatcccag caagtgtcga ccctgtggaa
     1201 gtggagtcca ctacacgcca cagcagaatg gactcaagac gaccagagtc tccatcactg
     1261 acctcctagc acacaccaat tacacgtttg agatctgggc agtgaatggc gtgtctaagt
     1321 acaaccctag cccagaccag tcagtgtctg tcacagtgac aaccaaccaa gcagcaccat
     1381 catccattgc tttggtccag gctaaagaag ttacaagata cagtgtggct ctggcttggc
     1441 tggaaccaga tcgaccaaac ggagtcatct tagaatatga agtgaaatat tatgaaaagg
     1501 atcagaatga acgaagctat cgcatagttc ggacagctgc caggaacaca gatatcaaag
     1561 gcctgaaccc tttgacttct tacgtcttcc acgtgcgagc caggaccgcc gctggctatg
     1621 gagacttcag cgaacccttg gaagtcacta ccaatacagt gccttcccga atcattggcg
     1681 acggggccaa ctctaccgtc ctgctggtct ccgtctctgg cagtgtagta ctcgtggtca
     1741 ttctcattgc ggcatttgtg atcagccgta gacggagtaa gtacagccaa gcaaagcaag
     1801 aagcagatga agagaagcat ttgaatcaag gtgttagaac atacgtggat ccctttacat
     1861 atgaagaccc caaccaggca gttcgagaat ttgccaaaga aatcgatgcc tcctgcatta
     1921 aaatcgaaaa ggtcattgga gttggcgaat ttggagaagt ctgcagtggg cgtctcaaag
     1981 tgcccggcaa gagagagatc tgtgtggcca tcaagactct gaaagctggt tatactgaca
     2041 agcagaggag agacttcctg agcgaggcca gcatcatggg acagtttgac cacccaaaca
     2101 taatccacct ggaaggcgtt gtcaccaaat gtaaaccagt aatgatcatc acggagtaca
     2161 tggagaacgg ctccttggac gctttcctca ggaagaatga tggccgattt acagtcattc
     2221 agctggtggg catgctccga ggcattggct cggggatgaa gtacttatct gatatgagct
     2281 atgtgcatcg agacctggct gccaggaaca ttctggtaaa cagcaacttg gtctgcaagg
     2341 tgtctgattt cggcatgtcc agggtgcttg aggatgaccc ggaagcagcc tatactacca
     2401 ggggcggcaa gattcccatc cggtggactg caccagaagc aattgcgtat cgtaaattta
     2461 cctcagccag tgacgtctgg agctacggaa tcgttatgtg ggaagtgatg tcatatggag
     2521 agaggccgta ctgggatatg tccaatcaag atgtgatcaa agccatcgag gaagggtacc
     2581 ggctaccccc gccaatggac tgccccattg ccctccatca gttaatgctg gactgttggc
     2641 agaaagagag aagcgacagg cctaaatttg ggcagatcgt caacatgttg gacaaactca
     2701 tccgcaaccc caacagcctg aagaggacag ggccagagag ttccagacca aacacagcct
     2761 tgttagatcc cagctcccct gaattctccg ccgtagtatc agtgggtgac tggctgcagg
     2821 ccatcaaaat ggaccggtat aaggacaact tcacagccgc cgggtacacg acactagaag
     2881 ctgtggttca catgagccag gatgacctgg cgcgaattgg catcaccgca atcacgcacc
     2941 agaataagat tttgagcagc gtccaggcga tgcgaaccca gatgcagcag atgcatggca
     3001 ggatggttcc tgtctgagcc agtaccgaac agactcaaaa ctctcgaata gtttacctca
     3061 tccatgcact ttaattgaag aactgcactt tttttacttc gtcttcgccc tctgaaatta
     3121 aaggaaaaca aacaaacaaa caaacaaaca aaaacacaaa tattatctgc agcgttgctt
     3181 ggtgtaagag attgctgaaa ccgcggggct tgtaatgaat gaccttgatc atcggaatta
     3241 aacccggagc cagtaatttc tcagaagaac tctgtccatc gctggtgtgt aaaatacatg
     3301 tacttatata aataaaactc tgcctctgag tttcgatgct gtattccccg tcagatacgt
     3361 ggcttttcaa gtcaccggaa tcctttctct gtctggaatt tcaacggaag gatttcatct
     3421 gtggcattaa ctacagtcat cactccttac tgggacgaag accctctgtg ccccaggagc
     3481 attgttaaag gactcaatgg tggctgtcag ggcttggttt ataccacaga ggaaaatgca
     3541 ggtgaaaacc acttggccca ttcatgctgc ctcgtcagtg cccaggacac ctggcggatt
     3601 gttaggacaa agaggggtgg gggtggggct agaaagacaa gaaaatggat ttttaaaaaa
     3661 atgcaaactc ccaagcccta ttacccctaa ccggacaaat gaggtttctt tgggctcgag
     3721 gctgtgccat ataaagtctt gtttgggaat gctacaaact tatcataact accttatgga
     3781 tagtgggctg agacaatcct gaatggagaa ttttcacaca cccctttaaa gaggcaactc
     3841 ccaaatttac aagggaatag attctggtat ctcagcctct cagcccttcc tgttgatgac
     3901 ataagccctt ggaagaaaag agaacacacc ctccttggtt ccttctgaat gtttttcttt
     3961 ggcttctctt ctgccagttc tgaggcaaag acacgacaaa acacctgtac ctgaaaagca
     4021 aaagaaatgt gtcaagtccc cttcgcccag gaaaacatca agctttggca gctgttctcc
     4081 agttgcacgg aggaacgtgc gtctcaagac accagctctg cagagccctt gctcccaaac
     4141 tccttgtggt tttatttata cgtatttcca tatttcattc ctgtacgtca ctgctgcatc
     4201 catgtggcag cacgtgacca aatggtacag gttttactat ggacgccagg tcaggcgcca
     4261 ccacgcagaa caaagccagt tccgtaagct gcctccgata agcattgctg aagtgacatt
     4321 ttacccaggg tgtgccattg cagtgataca aatatatttt tttcctagac taaaatatga
     4381 cctgaatatc tcttttgatg tgtgtaaata ggtgtgagtg agtgagtatg tgtgtgtgtg
     4441 tttgtgtgtg tgtgtgtgtg tgtgtgtgct tgcatacgtg tgtgcgtgcg tgacctcatg
     4501 cttagaactg cctgtgaatg ttgtggaatg ctatacctgg agagttctgg tttattacca
     4561 gttcaaagat agagagtcac atgatatacg agacccggag accatgtccg tccccttggg
     4621 aagacagctt ggaaatacta cgtgttcttt atccgtaagt gtaatgtgtc tgtcacattc
     4681 atcctaagaa gcagttcttt ggacagtttt caccccgatg gtggaatgag tttcttgata
     4741 tacacctgac tggccagttc cacaatggag agagaagggg atggaatccg tatagtgacc
     4801 ccggatggag tataagtcgc ctttgtttcc ctgcataaat gaccttgctg aatgcgaaca
     4861 aatatatgca attcatatac tttttggaga tgaacttaga tatgcgtgtc agccttgaga
     4921 tgacgtgtct ggagtaatac tttgtgtccc agtgtcacag aaaaatacat ccatgccagt
     4981 ggctcttgag gttaataatg tagttgggat ggaatggcct ctagcaaatc caggttcccc
     5041 aattacatgt agaaagttct ggtaattaat atgcagctaa ctacttctgc ccttgaaagt
     5101 acatcggtct tctagaatca gagttctggt gtatgaagat tcagtattga caggatatgt
     5161 tataccaaac tccagccagc atactgccat gttacttaac ctgagtggct gccttgctta
     5221 ttccgagcga tggttacaga agctgtgacc atttatataa gctataacat caaatcaggg
     5281 aattaaaaaa aaaaaaaaaa cgggggaaaa attctgaacc atatattgtt gaataagtaa
     5341 agaaaatcac caataaatat ttattgcatt ctgacagggt gtgtgtggca ttgtattctc
     5401 gtaactatgc cagagtgaca aagctaattc accccttttg gggggacctt aatatatttt
     5461 taaagggatg tgcctatgca ttgatgcctg aaaaatatgt gtaaaaaaaa agatgaagtt
     5521 gtacctttga gtggatcatc tttcccaaag gtcaggtggg aggaggtcaa cttccgggtc
     5581 tgtgttcagc tcaggatcga gcgctggtct cgtgagctgg aaggctaaaa tctgttcaaa
     5641 tctactaagc agcttcgagc tgttccctgc accaaatcaa gttgtttcac cacgtgtctg
     5701 caggctctga gttatttttg gcaatctgat aaatgaaatg ttctggtgtg tttaaaagaa
     5761 tagaggaaag gttgtgttcg caacctcatt tctgtgtgtt ctgagacctc ttgtattcat
     5821 ctgtgaaggg tacgtgtatc aatccataca ctcctatagc ctcaatgact tgtctgaaga
     5881 cacttaaatt ttgaccagta aaggaaagtt ctagaagcaa tattttcact cctttagcat
     5941 tgtccaaata acatcaagta ttaataaacg ctgaagagtg tatttatttt gtattactcc
     6001 aagtctgttg gaatatgcaa ggactgtggt tataattaga atgtataagg cataattata
     6061 atttagttca ttctgaaaaa gaagttagcc ggacatctct tgtttcatac atgttccaaa
     6121 ttttgagcaa tcttttgagt tagccataga tttttttcta ttttgttctt atttgtcaag
     6181 gtattttttt cttcccttca tgaactttag gtacacataa cttatgtcat ttatttatgg
     6241 tcttttatac ctagtttgta aagttgtaaa atagcaaact aaatgcaaag agtttgcatt
     6301 tgaaagtaat aaagtagttg ctgtattcaa acctgaaa
//
